Mitsuru Kimura

Summary

Publications

  1. doi request reprint Genetics of alcohol dependence
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center, Kanagawa, Japan
    Psychiatry Clin Neurosci 65:213-25. 2011
  2. doi request reprint Gender differences in the effects of ADH1B and ALDH2 polymorphisms on alcoholism
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center, Yokosuka, Kanagawa, Japan
    Alcohol Clin Exp Res 35:1923-7. 2011
  3. doi request reprint Trends in gastrectomy and ADH1B and ALDH2 genotypes in Japanese alcoholic men and their gene-gastrectomy, gene-gene and gene-age interactions for risk of alcoholism
    Akira Yokoyama
    National Hospital Organization Kurihama Medical and Addiction Center, 5 3 1 Nobi, Yokosuka, Kanagawa 239 0841, Japan
    Alcohol Alcohol 48:146-52. 2013
  4. ncbi request reprint ALDH2 promoter polymorphism has no effect on the risk for alcoholism
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center, 5 3 1 Nobi, Yokosuka, Kanagawa 2390841, Japan
    Alcohol Alcohol 41:368-71. 2006
  5. doi request reprint Genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 and liver cirrhosis, chronic calcific pancreatitis, diabetes mellitus, and hypertension among Japanese alcoholic men
    Akira Yokoyama
    National Hospital Organization Kurihama Medical and Addiction Center, Kanagawa, Japan
    Alcohol Clin Exp Res 37:1391-401. 2013
  6. doi request reprint Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center Yokosuka, 5 3 1 Nobi, Kanagawa, Japan
    Alcohol Clin Exp Res 33:799-803. 2009
  7. ncbi request reprint Association study of brain-derived neurotrophic factor gene polymorphism and alcoholism
    Sachio Matsushita
    National Hospital Organization, Kurihama Alcoholism Center, 5 3 1 Nobi, Yokosuka, Kanagawa 239 0841, Japan
    Alcohol Clin Exp Res 28:1609-12. 2004
  8. ncbi request reprint Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders
    Susumu Higuchi
    Institute of Clinical Research, National Alcoholism Center Kurihama Hospital, Yokosuka, Kanagawa, 239 0841, Japan
    Ann N Y Acad Sci 1025:472-80. 2004
  9. ncbi request reprint [Survey of physicians and alcohol-dependent patients in regard to the goals of treatment of alcohol dependence]
    Hitoshi Maesato
    National Hospital Organization, Kurihama Medical and Addiction Center, 5 3 1 Nobi, Yokosuka, Kanagawa 239 0841, Japan
    Nihon Arukoru Yakubutsu Igakkai Zasshi 48:64-9; quiz 70-5. 2013

Collaborators

Detail Information

Publications9

  1. doi request reprint Genetics of alcohol dependence
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center, Kanagawa, Japan
    Psychiatry Clin Neurosci 65:213-25. 2011
    ..Knowledge of the genetic basis of alcohol dependence is growing and leads to a better understanding of the biological mechanisms of addiction, which can help with strategies to prevent and treat this disease...
  2. doi request reprint Gender differences in the effects of ADH1B and ALDH2 polymorphisms on alcoholism
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center, Yokosuka, Kanagawa, Japan
    Alcohol Clin Exp Res 35:1923-7. 2011
    ..This study aimed to clarify gender differences in the effects of ADH1B and ALDH2 polymorphism on the development of alcohol dependence...
  3. doi request reprint Trends in gastrectomy and ADH1B and ALDH2 genotypes in Japanese alcoholic men and their gene-gastrectomy, gene-gene and gene-age interactions for risk of alcoholism
    Akira Yokoyama
    National Hospital Organization Kurihama Medical and Addiction Center, 5 3 1 Nobi, Yokosuka, Kanagawa 239 0841, Japan
    Alcohol Alcohol 48:146-52. 2013
    ..We investigated the trends in gastrectomy and alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) genotypes and their interactions in alcoholics...
  4. ncbi request reprint ALDH2 promoter polymorphism has no effect on the risk for alcoholism
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center, 5 3 1 Nobi, Yokosuka, Kanagawa 2390841, Japan
    Alcohol Alcohol 41:368-71. 2006
    ..To test for the possible association between mitochondrial aldehyde dehydrogenase (ALDH2) promoter polymorphism and alcoholism...
  5. doi request reprint Genetic polymorphisms of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 and liver cirrhosis, chronic calcific pancreatitis, diabetes mellitus, and hypertension among Japanese alcoholic men
    Akira Yokoyama
    National Hospital Organization Kurihama Medical and Addiction Center, Kanagawa, Japan
    Alcohol Clin Exp Res 37:1391-401. 2013
    ..2 allele) and active form of aldehyde dehydrogenase-2 (ALDH2) encoded by ALDH2*1/*1 (vs. *2 allele) increases the risk of alcoholism in East Asians...
  6. doi request reprint Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics
    Mitsuru Kimura
    National Hospital Organization, Kurihama Alcoholism Center Yokosuka, 5 3 1 Nobi, Kanagawa, Japan
    Alcohol Clin Exp Res 33:799-803. 2009
    ..This study aimed to compare personality profiles and clinical characteristics between alcoholics with active and inactive ALDH2...
  7. ncbi request reprint Association study of brain-derived neurotrophic factor gene polymorphism and alcoholism
    Sachio Matsushita
    National Hospital Organization, Kurihama Alcoholism Center, 5 3 1 Nobi, Yokosuka, Kanagawa 239 0841, Japan
    Alcohol Clin Exp Res 28:1609-12. 2004
    ..These lines of evidence suggested that BDNF might play some role in the development of or vulnerability to alcoholism and/or clinical characteristics of alcoholic individuals...
  8. ncbi request reprint Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders
    Susumu Higuchi
    Institute of Clinical Research, National Alcoholism Center Kurihama Hospital, Yokosuka, Kanagawa, 239 0841, Japan
    Ann N Y Acad Sci 1025:472-80. 2004
    ..Possible mechanisms of altered risk for these disorders are discussed...
  9. ncbi request reprint [Survey of physicians and alcohol-dependent patients in regard to the goals of treatment of alcohol dependence]
    Hitoshi Maesato
    National Hospital Organization, Kurihama Medical and Addiction Center, 5 3 1 Nobi, Yokosuka, Kanagawa 239 0841, Japan
    Nihon Arukoru Yakubutsu Igakkai Zasshi 48:64-9; quiz 70-5. 2013
    ..However, as for Alcohol Dependence Scale (ADS), there was no significant relationship with the treatment goal...