Yoonkyung Kim

Summary

Publications

  1. ncbi Systematic investigation of polyamidoamine dendrimers surface-modified with poly(ethylene glycol) for drug delivery applications: synthesis, characterization, and evaluation of cytotoxicity
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892
    Bioconjug Chem 19:1660-72. 2008
  2. ncbi PEGylated dendritic unimolecular micelles as versatile carriers for ligands of G protein-coupled receptors
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Bioconjug Chem 20:1888-98. 2009
  3. ncbi Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA
    Purinergic Signal 5:39-50. 2009
  4. ncbi Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Med Chem 52:2098-108. 2009
  5. ncbi Toward multivalent signaling across G protein-coupled receptors from poly(amidoamine) dendrimers
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Bioconjug Chem 19:406-11. 2008
  6. ncbi Cholesterol inhibits MMP-9 expression in human epidermal keratinocytes and HaCaT cells
    Sangmin Kim
    Department of Dermatology, Seoul National University College of Medicine, Laboratory of Cutaneous Aging Research, Clinical Research Institute, Seoul National University Hospital, Seoul 110 744, Republic of Korea
    FEBS Lett 581:3869-74. 2007

Collaborators

Detail Information

Publications6

  1. ncbi Systematic investigation of polyamidoamine dendrimers surface-modified with poly(ethylene glycol) for drug delivery applications: synthesis, characterization, and evaluation of cytotoxicity
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892
    Bioconjug Chem 19:1660-72. 2008
    ....
  2. ncbi PEGylated dendritic unimolecular micelles as versatile carriers for ligands of G protein-coupled receptors
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Bioconjug Chem 20:1888-98. 2009
    ..The current study demonstrates the feasibility of using short PEG chains in the design of carriers that target ligand-receptor interactions...
  3. ncbi Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA
    Purinergic Signal 5:39-50. 2009
    ..The present study demonstrates the potential of applying the functionalized congener concept to engineer dendrimer-based multivalent ligands for G protein-coupled receptors...
  4. ncbi Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Med Chem 52:2098-108. 2009
    ....
  5. ncbi Toward multivalent signaling across G protein-coupled receptors from poly(amidoamine) dendrimers
    Yoonkyung Kim
    Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Bioconjug Chem 19:406-11. 2008
    ..We envision that our multivalent dendrimer conjugates may improve overall pharmacological profiles compared to the monovalent GPCR ligands...
  6. ncbi Cholesterol inhibits MMP-9 expression in human epidermal keratinocytes and HaCaT cells
    Sangmin Kim
    Department of Dermatology, Seoul National University College of Medicine, Laboratory of Cutaneous Aging Research, Clinical Research Institute, Seoul National University Hospital, Seoul 110 744, Republic of Korea
    FEBS Lett 581:3869-74. 2007
    ..The inhibition of ERK and JNK decreased MbetaCD-induced MMP-9 expression. Therefore, our results suggest that cholesterol regulates MMP-9 expression through ERK and JNK-dependent pathways...