Nayoung Kim

Summary

Publications

  1. pmc Comparison of gastroesophageal reflux disease symptoms and proton pump inhibitor response using gastroesophageal reflux disease impact scale questionnaire
    So Young Jo
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 19:61-9. 2013
  2. pmc Effect of Helicobacter pylori Eradication on Functional Dyspepsia
    Sung Eun Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 19:233-43. 2013
  3. pmc Predictable Marker for Regression of Barrett's Esophagus by Proton Pump Inhibitor Treatment in Korea
    Hyun Jin Jo
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 19:210-8. 2013
  4. pmc Prevalence and risk factors of atrophic gastritis and intestinal metaplasia: a nationwide multicenter prospective study in Korea
    Young Eun Joo
    Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
    Gut Liver 7:303-10. 2013
  5. pmc Cost Effectiveness Associated with Helicobacter pylori Screening and Eradication in Patients Taking Nonsteroidal Anti-Inflammatory Drugs and/or Aspirin
    Hyun Jin Song
    School of Pharmacy, Sungkyunkwan University, Suwon, Korea
    Gut Liver 7:182-9. 2013
  6. pmc Seroprevalence of Helicobacter pylori Infection in Korean Health Personnel
    Hyun Young Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
    Gut Liver 7:648-54. 2013
  7. pmc Long-term follow up Helicobacter Pylori reinfection rate after second-line treatment: bismuth-containing quadruple therapy versus moxifloxacin-based triple therapy
    Min Soo Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, South Korea
    BMC Gastroenterol 13:138. 2013
  8. doi request reprint Prevalence and risk factors of atrophic gastritis and intestinal metaplasia in a Korean population without significant gastroduodenal disease
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, South Korea
    Helicobacter 13:245-55. 2008
  9. doi request reprint Helicobacter pylori infection and development of gastric cancer in Korea: long-term follow-up
    Nayoung Kim
    Departments of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    J Clin Gastroenterol 42:448-54. 2008
  10. doi request reprint Role of intestinal metaplasia subtyping in the risk of gastric cancer in Korea
    Kyung P Kang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Gastroenterol Hepatol 24:140-8. 2009

Collaborators

Detail Information

Publications98

  1. pmc Comparison of gastroesophageal reflux disease symptoms and proton pump inhibitor response using gastroesophageal reflux disease impact scale questionnaire
    So Young Jo
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 19:61-9. 2013
    ....
  2. pmc Effect of Helicobacter pylori Eradication on Functional Dyspepsia
    Sung Eun Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 19:233-43. 2013
    ..BACKGROUNDAIMS: This study evaluated the effect of Helicobacter pylori eradication on functional dyspepsia (FD), and the relationship between the changes of histological gastritis and FD symptom responses...
  3. pmc Predictable Marker for Regression of Barrett's Esophagus by Proton Pump Inhibitor Treatment in Korea
    Hyun Jin Jo
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 19:210-8. 2013
    ..The aim of this study was to determine the regression rate of BE by PPI and predictable markers related to regression...
  4. pmc Prevalence and risk factors of atrophic gastritis and intestinal metaplasia: a nationwide multicenter prospective study in Korea
    Young Eun Joo
    Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
    Gut Liver 7:303-10. 2013
    ..BACKGROUNDAIMS: Atrophic gastritis (AG) and intestinal metaplasia (IM) are premalignant gastric lesions. The aims of this study were to evaluate the prevalence of endoscopic AG and IM and to document the risk factors for these lesions...
  5. pmc Cost Effectiveness Associated with Helicobacter pylori Screening and Eradication in Patients Taking Nonsteroidal Anti-Inflammatory Drugs and/or Aspirin
    Hyun Jin Song
    School of Pharmacy, Sungkyunkwan University, Suwon, Korea
    Gut Liver 7:182-9. 2013
    ..BACKGROUNDAIMS: This study was performed to investigate the cost effectiveness of Helicobacter pylori screening/eradication in South Korean patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and/or aspirin...
  6. pmc Seroprevalence of Helicobacter pylori Infection in Korean Health Personnel
    Hyun Young Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
    Gut Liver 7:648-54. 2013
    ..The aims of this study were to evaluate whether doctors and nurses in a single hospital were at an increased risk of acquiring Helicobacter pylori infection in 2011 and to identify risk factors for H. pylori seroprevalence...
  7. pmc Long-term follow up Helicobacter Pylori reinfection rate after second-line treatment: bismuth-containing quadruple therapy versus moxifloxacin-based triple therapy
    Min Soo Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, South Korea
    BMC Gastroenterol 13:138. 2013
    ..pylori) treatment in high prevalence area of H. pylori. The aim of our study was to evaluate the reinfection rate of H. pylori after second-line treatment that would determine the long-term follow up effect of the rescue therapy...
  8. doi request reprint Prevalence and risk factors of atrophic gastritis and intestinal metaplasia in a Korean population without significant gastroduodenal disease
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, South Korea
    Helicobacter 13:245-55. 2008
    ..pylori virulence factors, and environmental and host factors, in Korean population without significant gastroduodenal disease...
  9. doi request reprint Helicobacter pylori infection and development of gastric cancer in Korea: long-term follow-up
    Nayoung Kim
    Departments of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    J Clin Gastroenterol 42:448-54. 2008
    ..This study was performed to investigate the effect of H. pylori infection on gastric cancer development and to determine to what extent H. pylori eradication is likely to reduce the prevalence of gastric cancer...
  10. doi request reprint Role of intestinal metaplasia subtyping in the risk of gastric cancer in Korea
    Kyung P Kang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Gastroenterol Hepatol 24:140-8. 2009
    ..Intestinal metaplasia (IM) is regarded as a premalignant condition; it is classified into subtypes I, II and III. The aim of this study was to evaluate whether the subtypes of IM were associated with progression to gastric cancer...
  11. doi request reprint Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study
    Cheol Min Shin
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    Int J Cancer 133:2034-42. 2013
    ..pylori eradication decreases aberrant DNA methylation with gene-specific manner. Methylation level in MOS is associated with IM and may be used as a surrogate marker for gastric cancer risk, regardless of H. pylori eradication history...
  12. ncbi request reprint The effects of genetic polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced gastroduodenal diseases in Korea
    Jung Mook Kang
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    J Clin Gastroenterol 43:420-8. 2009
    ..The present study was performed to evaluate whether or not the genetic polymorphisms of IL-6, IL-8, and IL-10 are associated with gastroduodenal disease in the Korean population...
  13. doi request reprint Clinical meaning of pepsinogen test and Helicobacter pylori serology in the health check-up population in Korea
    Hyun Young Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Bundang gu, South Korea
    Eur J Gastroenterol Hepatol 21:606-12. 2009
    ..pylori serology in a Korean population presenting for a health check-up...
  14. ncbi request reprint [Primary antibiotic resistance of Helicobacter pylori strains and eradication rate according to gastroduodenal disease in Korea]
    Jae Yeon Kim
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Korean J Gastroenterol 58:74-81. 2011
    ..This study was performed to evaluate whether the prevalence rates of primary antibiotic resistance in Helicobacter pylori (H. pylori) isolates and the eradication rate of H. pylori could be different between cancer and non-cancer patients...
  15. ncbi request reprint The effect of coffee consumption on the development of hepatocellular carcinoma in hepatitis B virus endemic area
    Eun Sun Jang
    Department of Internal Medicine, Seoul National University College of Medicine, Seongnam si, Korea
    Liver Int 33:1092-9. 2013
    ..To elucidate the relationship between lifetime coffee consumption and the risk of HCC development under the consideration of replication status of HBV...
  16. doi request reprint Bismuth-containing quadruple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate in Korea
    Byoung Hwan Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
    Helicobacter 15:38-45. 2010
    ..The aim of this study was to evaluate the efficacy of bismuth-containing quadruple therapy as second-line treatment for H. pylori infection based on treatment duration...
  17. doi request reprint The discrepancy between genetic polymorphism of p53 codon 72 and the expression of p53 protein in Helicobacter pylori-associated gastric cancer in Korea
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, 300 Gumi dong, Bundang gu, Seongnam, Gyeonggi do 463 707, South Korea
    Dig Dis Sci 55:101-10. 2010
    ..pylori-associated gastroduodenal diseases, but p53 immunostaining did not correlate with those of the p53 genetic polymorphism analysis...
  18. ncbi request reprint [Clinical characteristics of patients diagnosed as peptic ulcer disease in the third referral center in 2007]
    Jin Joo Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, 82 Gumiro 173 gil, Bundang gu, Seongnam 463 707, Korea
    Korean J Gastroenterol 59:338-46. 2012
    ..The purpose of this study was to evaluate the risk factors and general characteristics of Korean patients diagnosed as PUD at a single third referral center...
  19. doi request reprint An epidemiologic study on the incidence and significance of HFE mutations in a Korean cohort with nonalcoholic fatty liver disease
    Sang Hyub Lee
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam si, Geonggi do, Korea
    J Clin Gastroenterol 44:e154-61. 2010
    ..The incidence and significance of HFE mutations (C282Y, H63D, and S65C) in nonalcoholic fatty liver disease (NAFLD) has not been investigated in Korea...
  20. ncbi request reprint Combinations containing amoxicillin-clavulanate and tetracycline are inappropriate for Helicobacter pylori eradication despite high in vitro susceptibility
    Jae Hee Cheon
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Korea
    J Gastroenterol Hepatol 21:1590-5. 2006
    ..The purpose of the present paper was to evaluate the efficacy and tolerability of amoxicillin-clavulanate and tetracycline-based quadruple therapy as an alternative second-line treatment for H. pylori infection...
  21. ncbi request reprint Effects of Helicobacter pylori Infection on gastric mucin expression
    Hyung Min Kang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Clin Gastroenterol 42:29-35. 2008
    ..pylori-associated gastroduodenal diseases. In addition, MUC5AC and MUC6 expressional changes were investigated before and after H. pylori eradication...
  22. doi request reprint Intrafamilial aggregation of gastric cancer: a comprehensive approach including environmental factors, Helicobacter pylori virulence, and genetic susceptibility
    Cheol Min Shin
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    Eur J Gastroenterol Hepatol 23:411-7. 2011
    ..Familial clustering has been reported in gastric cancer (GC). However, the mechanism of the intrafamilial aggregation of GC remains unclear...
  23. ncbi request reprint Helicobacter pylori genotyping findings from multiple cultured isolates and mucosal biopsy specimens: strain diversities of Helicobacter pylori isolates in individual hosts
    Young Sun Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Eur J Gastroenterol Hepatol 21:522-8. 2009
    ..To determine whether the genotypes of virulent genes in Helicobacter pylori isolates and mucosal biopsy specimens differ in individuals, and to investigate whether different isolates from single hosts show strain differences...
  24. ncbi request reprint Second-line treatment for Helicobacter pylori infection: 10-day moxifloxacin-based triple therapy versus 2-week quadruple therapy
    Jung Mook Kang
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea
    Helicobacter 12:623-8. 2007
    ..The aim of this study was to test the efficacy of 10-day moxifloxacin-based triple therapy versus 2-week quadruple therapy for the second-line treatment of Helicobacter pylori infection...
  25. doi request reprint Risk factors for peptic ulcer bleeding in terms of Helicobacter pylori, NSAIDs, and antiplatelet agents
    Jung Mook Kang
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Scand J Gastroenterol 46:1295-301. 2011
    ..This study was performed to identify the risk factors for peptic ulcer bleeding compared with non-bleeding peptic ulcer disease (PUD)...
  26. doi request reprint Gastroprotective action of Cochinchina momordica seed extract is mediated by activation of CGRP and inhibition of cPLA(2)/5-LOX pathway
    Jung Mook Kang
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    Dig Dis Sci 54:2549-60. 2009
    ..Furthermore, CGRP-NO pathway was found to play an important role in these gastroprotective effects of SK-MS10...
  27. doi request reprint Relationship of interleukin-1β levels and gastroesophageal reflux disease in Korea
    Jin Joo Kim
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    J Gastroenterol Hepatol 28:90-8. 2013
    ..The relationship of gastric mucosal IL-1β level and GERD was evaluated in the Korean population...
  28. ncbi request reprint Eradication rates of helicobacter pylori infection with second-line treatment: non-ulcer dyspepsia compared to peptic ulcer disease
    Su Jin Chung
    The Liver Research Institute, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Hepatogastroenterology 54:1293-6. 2007
    ..Therefore, we retrospectively analyzed the difference in eradication rates of a second-line quadruple therapy for NUD and PUD patients...
  29. doi request reprint Change in antibiotic resistance of Helicobacter pylori strains and the effect of A2143G point mutation of 23S rRNA on the eradication of H. pylori in a single center of Korea
    Tae Jun Hwang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    J Clin Gastroenterol 44:536-43. 2010
    ..pylori is not known in Korea. This study was done to evaluate the prevalence of primary antibiotic resistance of H. pylori, and to evaluate the effect of point mutations of 23S rRNA on the rate of eradication of H. pylori...
  30. ncbi request reprint [Diagnosis and treatment guidelines for Helicobacter pylori infection in Korea]
    Nayoung Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Seoul, Korea
    Korean J Gastroenterol 54:269-78. 2009
    ..Herein, Korean College of Helicobacter and Upper Gastrointestinal Research proposes a diagnostic and treatment guideline based on currently available evidence...
  31. ncbi request reprint [The risk factors for colonic diverticular bleeding]
    Seungchul Suh
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul, Korea
    Korean J Gastroenterol 60:349-54. 2012
    ..The purpose of this study was to evaluate the risk factors for colonic diverticular bleeding diagnosed by colonoscopic examination...
  32. doi request reprint The correlation of endoscopic and histological diagnosis of gastric atrophy
    Alisher Eshmuratov
    Department of Internal Medicine, Seoul National University Bundang Hospital, 300 Gumi dong, Bundang gu, Seongnam, Gyeonggi do 463 707, South Korea
    Dig Dis Sci 55:1364-75. 2010
    ..Gastric atrophy is a premalignant condition. The aim of this study was to evaluate the correlation between histological and endoscopic findings of atrophy, and to analyze the affecting factors...
  33. ncbi request reprint Institutional difference of antibiotic resistance of Helicobacter pylori strains in Korea
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Seoul, Korea
    J Clin Gastroenterol 40:683-7. 2006
    ..pylori...
  34. ncbi request reprint Long-term outcomes after Helicobacter pylori eradication with second-line, bismuth-containing quadruple therapy in Korea
    Jae Hee Cheon
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 744, Korea
    Eur J Gastroenterol Hepatol 18:515-9. 2006
    ..To determine the long-term outcomes in terms of Helicobacter pylori and ulcer recurrence after second-line eradication with bismuth-containing quadruple regimens in Korea...
  35. ncbi request reprint Efficacy of moxifloxacin-based triple therapy as second-line treatment for Helicobacter pylori infection
    Jae Hee Cheon
    Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Helicobacter 11:46-51. 2006
    ..Our aim is to evaluate the efficacy and tolerability of moxifloxacin-based triple therapy as an alternative second-line treatment for H. pylori infection...
  36. ncbi request reprint Influence of IL1B polymorphism on CpG island hypermethylation in Helicobacter pylori-infected gastric cancer
    Eun Joo Yoo
    Laboratory of Epigenetics, Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea
    Virchows Arch 456:647-52. 2010
    ..pylori infection and IL1B-511T/T allele...
  37. doi request reprint Clinical outcomes of two-week sequential and concomitant therapies for Helicobacter pylori eradication: a randomized pilot study
    Ji Hyun Lim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Bundang gu, Seongnam, Korea
    Helicobacter 18:180-6. 2013
    ..To investigate which regimen is a reasonable choice for Korean population, we performed two pilot studies with sequential and concomitant therapies...
  38. ncbi request reprint [The trend of eradication rates of second-line quadruple therapy containing metronidazole for Helicobacter pylori infection: an analysis of recent eight years]
    Jeong Hoon Lee
    Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Korean J Gastroenterol 46:94-8. 2005
    ..However, most were limited by short follow-up periods. Hence, we evaluated the efficacy of the metronidazole containing quadruple therapy as a second line treatment from April, 1996 through July, 2004...
  39. doi request reprint Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling
    Nayoung Kim
    Department of Internal Medicine, Seoul National University, Bundang Hospital, Seongnam, Gyeonggi Do, Seoul, South Korea
    J Gastroenterol Hepatol 24:480-7. 2009
    ..However, the specific anti-cancer effects of celecoxib on gastric cancer cells have not been clarified. The present in vitro study was carried out to investigate the mechanism involved in the anti-gastric cancer effects of celecoxib...
  40. doi request reprint Long-term follow up of Helicobacter pylori IgG serology after eradication and reinfection rate of H. pylori in South Korea
    Jung Hoon Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, South Korea
    Helicobacter 13:288-94. 2008
    ..pylori infection rate decreases. The aim of this study was to investigate the long-term follow up of H. pylori IgG, and to evaluate the reinfection rate of H. pylori in Korea...
  41. doi request reprint Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae
    Cheol Min Shin
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    J Pathol 226:654-65. 2012
    ..05). To summarize, among the candidate genes, DNA methylation of MOS may reflect the duration of H. pylori exposure and may be a marker for the development of GC...
  42. ncbi request reprint Higher prevalence of obesity in gastric cardia adenocarcinoma compared to gastric non-cardia adenocarcinoma
    Yuri Cho
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Dig Dis Sci 57:2687-92. 2012
    ..The objective of our research was to evaluate the relationship between obesity and GCA compared to non-cardia adenocarcinoma...
  43. ncbi request reprint Analysis of the 3' variable region of the cagA gene of Helicobacter pylori isolated in Koreans
    Kee Don Choi
    Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Dig Dis Sci 52:960-6. 2007
    ..Seventy-six strains (96.2%) were the East Asian type. In conclusion, there was no significant difference between the number of EPIYA motifs or CagA subtypes and various gastroduodenal diseases in Korea...
  44. doi request reprint Comparison of CpG island hypermethylation and repetitive DNA hypomethylation in premalignant stages of gastric cancer, stratified for Helicobacter pylori infection
    Seog Yun Park
    Department of Pathology, Brain Korea 21 Project for Medical Science, Seoul National University College of Medicine, South Korea
    J Pathol 219:410-6. 2009
    ..pylori infection...
  45. ncbi request reprint Effect of the CYP2C19 polymorphism on the eradication rate of Helicobacter pylori infection by 7-day triple therapy with regular proton pump inhibitor dosage
    Jung Mook Kang
    Department of Internal Medicine and Liver Research Institute, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Gastroenterol Hepatol 23:1287-91. 2008
    ..We investigated whether the CYP2C19 genotype plays a role in the eradication rate of Helicobacter pylori (H. pylori) infection in patients receiving pantoprazole- or esomeprazole-based triple therapy...
  46. doi request reprint Genome-wide DNA methylation profiles in noncancerous gastric mucosae with regard to Helicobacter pylori infection and the presence of gastric cancer
    Cheol Min Shin
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    Helicobacter 16:179-88. 2011
    ..To determine genome-wide DNA methylation profiles induced by Helicobacter pylori (H. pylori) infection and to identify methylation markers in H. pylori-induced gastric carcinogenesis...
  47. doi request reprint Role of Helicobacter pylori infection in aberrant DNA methylation along multistep gastric carcinogenesis
    Cheol Min Shin
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    Cancer Sci 101:1337-46. 2010
    ..pylori. Aberrant methylation of THBD might provide a link between H. pylori infection and development of GC...
  48. doi request reprint Moxifloxacin-containing triple therapy as second-line treatment for Helicobacter pylori infection: effect of treatment duration and antibiotic resistance on the eradication rate
    Hyuk Yoon
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Helicobacter 14:77-85. 2009
    ..We also investigated the effect of treatment duration and antibiotic resistance on the eradication rate of this therapy...
  49. doi request reprint Changes in prevalence of Helicobacter pylori infection after subtotal gastrectomy
    Seungchul Suh
    Department of Internal Medicine, Seoul National University, Gyeonggi Do, Korea
    Hepatogastroenterology 59:646-8. 2012
    ..There have been few reports comparing pre and postoperative prevalence of Helicobacter pylori infection and gastritis in patients with gastric cancer surgery...
  50. doi request reprint Short hairpin RNA induces methylation of hepatitis B virus covalently closed circular DNA in human hepatoma cells
    Hyun Kyung Park
    Department of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
    Biochem Biophys Res Commun 436:152-5. 2013
    ..These results confirm the feasibility of RdDM of HBV cccDNA in human cells. Lentiviral vector-mediated transfer of shRNA may be used as a tool for novel transcriptional modulation by epigenetic modification of HBV cccDNA. ..
  51. doi request reprint Long-term follow-up Helicobacter pylori reinfection rate and its associated factors in Korea
    Min Soo Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, South Korea
    Helicobacter 18:135-42. 2013
    ..The aim of this study is to evaluate the long-term reinfection rate of H. pylori and to investigate its associated risk factors in South Korea...
  52. doi request reprint Prevalence of primary and secondary antimicrobial resistance of Helicobacter pylori in Korea from 2003 through 2012
    Jung Won Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    Helicobacter 18:206-14. 2013
    ..The aim of this study was to estimate the prevalence of primary and secondary resistance of H. pylori isolates to antibiotics and to characterize the risk factors associated with antimicrobial resistance in Korea...
  53. ncbi request reprint [Trial of moxifloxacin-containing triple therapy after initial and second-line treatment failures for Helicobacter pylori infection]
    Jae Hee Cheon
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
    Korean J Gastroenterol 45:111-7. 2005
    ..Bismuth-based, second-line therapy is also associated with failures in more than 20% of cases in Korea. Our aim was to evaluate the efficacy and tolerability of third-line therapy containing moxifloxacin as a rescue in Korea...
  54. doi request reprint The effects of probiotics on PPI-triple therapy for Helicobacter pylori eradication
    Mi Na Kim
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea
    Helicobacter 13:261-8. 2008
    ..This study was performed to evaluate whether the addition of probiotics to proton pump inhibitor (PPI)-based triple therapy increases the likelihood of successful Helicobacter pylori eradication...
  55. ncbi request reprint [The trend of eradication rates of first-line triple therapy for Helicobacter pylori infection: single center experience for recent eight years]
    You Sik Choi
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Yeongeon Dong, Jongno gu, Seoul, Korea
    Korean J Gastroenterol 48:156-61. 2006
    ..However, the recent trend of eradication rates of H. pylori using first-line triple regimens has been rarely issued. Therefore, we aimed to determine the trend of H. pylori eradication rates in single center for recent eight years...
  56. doi request reprint Validation of diagnostic tests for Helicobacter pylori with regard to grade of atrophic gastritis and/or intestinal metaplasia
    Cheol Min Shin
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Helicobacter 14:512-9. 2009
    ..To evaluate the validity of the biopsy-based tests (histology, culture, and urease test) and serology in detecting current Helicobacter pylori infection against a background of atrophic gastritis (AG) or intestinal metaplasia (IM)...
  57. doi request reprint The role of serum pepsinogen and gastrin test for the detection of gastric cancer in Korea
    Jung Mook Kang
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
    Helicobacter 13:146-56. 2008
    ..This study was performed to determine whether serum pepsinogen (PG) and gastrin testing can be used to detect gastric cancer in Korea...
  58. doi request reprint Ethanol potentiates hepatitis B virus replication through oxidative stress-dependent and -independent transcriptional activation
    Bo Young Min
    Department of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
    Biochem Biophys Res Commun 431:92-7. 2013
    ..In conclusion, ethanol enhances transcriptional activity of HBV promoters in human hepatoma cells in an oxidative stress-independent manner; and CYP2E1-mediated oxidative stress potentiates the ethanol-induced transactivation of HBV...
  59. doi request reprint Stomach cancer risk in gastric cancer relatives: interaction between Helicobacter pylori infection and family history of gastric cancer for the risk of stomach cancer
    Cheol Min Shin
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea
    J Clin Gastroenterol 44:e34-9. 2010
    ..pylori) infection and family history of gastric cancer in gastric carcinogenesis...
  60. ncbi request reprint Association between alcohol intake and risk for gastric cancer with regard to ALDH2 genotype in the Korean population
    Cheol Min Shin
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    Int J Epidemiol 40:1047-55. 2011
    ..The relationship between alcohol intake and the risk for gastric cancer is not fully understood. The association between alcohol consumption and the risk for gastric cancer was investigated in the Korean population with the ALDH2 genotype...
  61. doi request reprint Helicobacter pylori-negative gastric cancer in South Korea: incidence and clinicopathologic characteristics
    Hyuk Yoon
    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea
    Helicobacter 16:382-8. 2011
    ..pylori detection rates decrease with the progression of gastric atrophy and intestinal metaplasia. The aim of this study was to evaluate the incidence and clinicopathologic characteristics of HPIN-GC in South Korea...
  62. ncbi request reprint [Clinical significance of incidentally detected eosinophilic esophagitis with pathologic review]
    Youn Mu Jung
    Department of Internal Medicine, Seoul National University Bundang Hospital, Bundang gu, Seongnam, Korea
    Korean J Gastroenterol 55:162-8. 2010
    ..The prevalence is largely unknown. This study was performed to evaluate the detection rate of EE diagnosed based on pathologic criteria and to define the clinical characteristics of EE in Korea...
  63. doi request reprint Prevalence and clinicopathologic characteristics of gastric cardia cancer in South Korea
    Ji Yeon Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, South Korea
    Helicobacter 17:358-68. 2012
    ..However, few studies have been conducted in Asia. The aims of this study were to estimate the prevalence of GCC and to evaluate differences of clinicopathologic characteristics between GCC and GNCC in South Korea...
  64. doi request reprint c-Myc-mediated overexpression of miR-17-92 suppresses replication of hepatitis B virus in human hepatoma cells
    Yong Jin Jung
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
    J Med Virol 85:969-78. 2013
    ..These results demonstrated negative feedback suppression of HBV replication by the miR-17-92 polycistron...
  65. doi request reprint Replicative activity of hepatitis B virus is negatively associated with methylation of covalently closed circular DNA in advanced hepatitis B virus infection
    Jin Wook Kim
    Department of Medicine, Seoul National University Bundang Hospital, Seongnam, South
    Intervirology 54:316-25. 2011
    ....
  66. pmc Effects of coffee, smoking, and alcohol on liver function tests: a comprehensive cross-sectional study
    Eun Sun Jang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 166 Gumi ro, Bundang gu, Seongnam si, 463 707, Gyeonggi Do, Republic of Korea
    BMC Gastroenterol 12:145. 2012
    ..The aim of this study was to elucidate whether drinking coffee, smoking, or drinking alcohol have independent effects on LFTs in Korean health-check examinees...
  67. doi request reprint The clinical outcome of elderly patients with acute pancreatitis is not different in spite of the different etiologies and severity
    Jang Eon Kim
    Division of Gastroenterology, Department of Internal Medicine, Seoul Medical Center, 171 1 Samsung dong, Gangnam Gu, Seoul 135 090, South Korea
    Arch Gerontol Geriatr 54:256-60. 2012
    ..5% vs. 0.7%, p=0.148) were not different between the age-groups. In our study, chronological age had no significant influence on the clinical outcome in spite of the different etiologies and severity of acute pancreatitis...
  68. doi request reprint Hepatocellular carcinoma in older adults: clinical features, treatments, and survival
    Sang Hyub Lee
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam si, Gyeonggi Do, Korea
    J Am Geriatr Soc 59:241-50. 2011
    ..To evaluate the clinical features, treatments, stages, and survival in older adults with hepatocellular carcinoma (HCC)...
  69. pmc Dual Therapy Trial Using Esomeprazole and Amoxicillin as Third-line Rescue Therapy for Helicobacter pylori Infection
    Hyun Kyung Park
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
    Clin Endosc 44:33-7. 2011
    ..The purpose of this study was to evaluate the efficacy and tolerability of dual therapy consisting of esomeprazole and amoxicillin as a rescue therapy for Helicobacter pylori infection...
  70. ncbi request reprint Detection rate of Helicobacter pylori against a background of atrophic gastritis and/or intestinal metaplasia
    Ji Youn Yoo
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, South Korea
    J Clin Gastroenterol 41:751-5. 2007
    ..To evaluate the detection rate of the CLOtest, Giemsa stain, and culture for the diagnosis of Helicobacter pylori organisms in patients with or without atrophic gastritis (AG) and/or intestinal metaplasia (IM)...
  71. doi request reprint Endoscopic self-expandable metallic stent placement in malignant pyloric or duodenal obstruction: does chemotherapy affect stent patency?
    Byung Hyo Cha
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
    Asia Pac J Clin Oncol 9:162-8. 2013
    ..We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy...
  72. doi request reprint Management for CBD stone-related mild to moderate acute cholangitis: urgent versus elective ERCP
    Sang Eon Jang
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 166 Gumi ro, Bundang gu, Seoungnam si, Gyeonggi do 463 707, South Korea
    Dig Dis Sci 58:2082-7. 2013
    ..However, it remains to be determined how early biliary decompression should be performed and elective intervention would be comparable to urgent intervention, in case of mild to moderate choledocholithiasis associated cholangitis...
  73. ncbi request reprint The effects of genetic polymorphisms of IL-1 and TNF-A on Helicobacter pylori-induced gastroduodenal diseases in Korea
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    Helicobacter 11:105-12. 2006
    ..To evaluate whether or not genetic polymorphism of IL-1B, IL-1RN, and TNF-Alpha is an important factor in the different expression of gastroduodenal diseases after Helicobacter pylori infection...
  74. pmc Gastroprotective effect of Cochinchina momordica seed extract in nonsteroidal anti-inflammatory drug-induced acute gastric damage in a rat model
    Ji Hwan Lim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
    Gut Liver 8:49-57. 2014
    ..In this study, we evaluated the gastroprotective effects of SK-MS10 in the nonsteroidal anti-inflammatory drug (NSAID)-induced gastric damage rat model...
  75. pmc Correlation between Endoscopic and Histological Diagnoses of Gastric Intestinal Metaplasia
    Ji Hwan Lim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
    Gut Liver 7:41-50. 2013
    ..Intestinal metaplasia (IM) is a premalignant condition. This study aimed to evaluate the correlation between endoscopic and histological findings of IM...
  76. pmc Pretreatment serum HBsAg-to-HBV DNA ratio predicts a virologic response to entecavir in chronic hepatitis B
    Joon Chang Song
    Department of Internal Medicine, Seoul National University College of Medicine, Seongnam, Korea
    Korean J Hepatol 17:268-73. 2011
    ..In this study we sought to determine whether the VR can be predicted from HBsAg titers in nucleos(t)ide-naive chronic hepatitis B (CHB) patients treated with entecavir...
  77. ncbi request reprint Submucosal saline-epinephrine injection in colon polypectomy: appropriate indication
    Sang Hyub Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital
    Hepatogastroenterology 55:1589-93. 2008
    ..This study was performed to determine the appropriate indications for submucosal saline-epinephrine injection...
  78. doi request reprint Predictive power of serum pepsinogen tests for the development of gastric cancer in comparison to the histologic risk index
    Min Sun Kwak
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
    Dig Dis Sci 55:2275-82. 2010
    ....
  79. ncbi request reprint Age as a clinical predictor of relapse after induction therapy in ulcerative colitis
    Eun Sun Jang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Gumi dong 300, Bundang gu, Seongnam si, Republic of Korea
    Hepatogastroenterology 56:1304-9. 2009
    ..We compared the clinical characteristics between older and younger age groups in South Korea to elucidate the impact of age on relapse in UC...
  80. doi request reprint Chronic hepatitis B, non-Hodgkin's lymphoma, and effect of prophylactic antiviral therapy
    Yeo Myeong Kim
    Department of Internal Medicine, Seoul National University, College of Medicine, Seoul National University Bundang Hospital, Gumi dong 300, Bundang gu, Seongnam si, Gyeonggi Do, Republic of Korea
    J Clin Virol 51:241-5. 2011
    ..Hepatitis B virus (HBV) infection can be associated with non-Hodgkin's lymphoma (NHL), and prophylactic antiviral therapy is recommended for NHL patients with chronic HBV infection who are receiving anticancer chemotherapy...
  81. ncbi request reprint Seroconversion of Helicobacter pylori in Korean male employees
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    Scand J Gastroenterol 40:1021-7. 2005
    ..As no published estimates are available on the seroconversion rate of H. pylori in the Korean population, the purpose of this study was to evaluate the incidence and prevalence of H. pylori infection in male Korean employees...
  82. ncbi request reprint [Recent etiology and clinical features of acute viral hepatitis in a single center of Korea]
    Hyung Min Kang
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
    Korean J Hepatol 13:495-502. 2007
    ..The aim of this study was to investigate the recent etiology and the clinical features of acute viral hepatitis in a single center of Korea...
  83. doi request reprint Hepatic iron, serum ferritin, HFE mutation, and hepatic fibrosis in chronic hepatitis C
    Ji Eon Won
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
    Intervirology 52:239-46. 2009
    ..We studied the status of hepatic iron deposition and its relationship with blood iron indices, liver histology, and HFE gene mutations in Korean patients with chronic hepatitis C (CH-C)...
  84. pmc The Role of CDX2 in Intestinal Metaplasia Evaluated Using Immunohistochemistry
    Byoung Hwan Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
    Gut Liver 6:71-7. 2012
    ..Intestinal metaplasia (IM) has been regarded as a premalignant condition. This study evaluated the role of the transforming factor CDX2 according to the severity and type of IM...
  85. pmc Serum prohepcidin levels in chronic hepatitis C, alcoholic liver disease, and nonalcoholic fatty liver disease
    Sang Hyub Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
    Korean J Hepatol 16:288-94. 2010
    ..Prohepcidin is an easily measurable precursor of hepcidin, which is a key regulator of iron homeostasis. This study investigated the serum prohepcidin levels in patients with various chronic liver diseases with various etiologies...
  86. doi request reprint Lafutidine versus lansoprazole in combination with clarithromycin and amoxicillin for one versus two weeks for Helicobacter pylori eradication in Korea
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
    Helicobacter 13:542-9. 2008
    ..The aim of the present study was to test the efficacy of 7- or 14-day lafutidine-clarithromycin-amoxicillin therapy versus a lansoprazole-based regimen for Helicobacter pylori eradication...
  87. ncbi request reprint Gene expression of AGS cells stimulated with released proteins by Helicobacter pylori
    Nayoung Kim
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoungnam, Gyeonggi Do, Korea
    J Gastroenterol Hepatol 23:643-51. 2008
    ..The present study was performed to evaluate the gene expression of AGS gastric cancer cells stimulated with released proteins by H. pylori...
  88. ncbi request reprint Histologic characteristics of gastric polyps in Korea: emphasis on discrepancy between endoscopic forceps biopsy and endoscopic mucosal resection specimen
    Won Jae Yoon
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul, Korea
    World J Gastroenterol 12:4029-32. 2006
    ..To investigate histological characteristics of gastric polyps in the Korean population...
  89. pmc The Long-term Clinical Efficacy of Biofeedback Therapy for Patients With Constipation or Fecal Incontinence
    Byoung Hwan Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 16:177-85. 2010
    ..There has been a controversy regarding the usefulness of biofeedback therapy for functional constipation or fecal incontinence. This study was performed to investigate the long-term clinical efficacy of biofeedback therapy...
  90. pmc Two Cases of Chronic Idiopathic Intestinal Pseudo-obstruction with Different Clinical Features
    Byoung Hwan Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    J Neurogastroenterol Motil 16:83-9. 2010
    ..In conclusion, CIPO is a difficult disorder with various clinical manifestations and different treatment modalities, therefore individualized diagnostic and therapeutic approaches are needed...
  91. pmc Effect of Low-dose, Enteric Coated Aspirin on Gastrointestinal Bleeding in Patients with Coronary Artery Disease
    Chang Kyu Choi
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    Gut Liver 2:99-104. 2008
    ..This study was performed to determine whether low-dose aspirin and/or clopidogrel can induce gastrointestinal bleeding and gastroduodenal mucosal injury...
  92. doi request reprint Mutations of Helicobacter pylori associated with fluoroquinolone resistance in Korea
    Jung W Lee
    Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi Do, Korea
    Helicobacter 16:301-10. 2011
    ..This study was performed to investigate the distribution of gyrA point mutations and to evaluate the impact of the mutations on second-line H. pylori eradication therapy...