Manuka honey: histological effect on respiratory mucosaShaun J Kilty
Department of Otolaryngology Head and Neck Surgery, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, ON K1Y 4E9, Canada
Am J Rhinol Allergy 24:e63-6. 2010
..The purpose of this study was to determine if the application of manuka honey to respiratory epithelium would result in histological evidence of epithelial injury...
Clinical predictors of peritonsillar abscess in adultsShaun J Kilty
Department of Otolaryngology, The University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada
J Otolaryngol Head Neck Surg 37:165-8. 2008
..The secondary objective was to identify the prevalence of tobacco smoking behaviour in this group of patients with peritonsillitis...
Bacterial biofilms and the pathophysiology of chronic rhinosinusitisDakheelallah Al-Mutairi
Department of Otolaryngology Head and Neck Surgery, Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
Curr Opin Allergy Clin Immunol 11:18-23. 2011
..Lastly, to provide an overview of the current and potential future treatments for bacterial biofilms in CRS...
Socioeconomic status: a disease modifier of chronic rhinosinusitis?Shaun J Kilty
Department of Otolaryngology Head and Neck Surgery, Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada
Rhinology 49:533-7. 2011
..Our purpose was to determine if there is a correlation between socio-economic status (SES) and CRS severity as measured by the LMS, and if there is an association between depression symptoms and the severity of CRS using the LMS...
Methylglyoxal: (active agent of manuka honey) in vitro activity against bacterial biofilmsShaun J Kilty
Department of Otolaryngology Head and Neck Surgery, The Ottawa Hospital TOH, Ottawa, Ontario, Canada
Int Forum Allergy Rhinol 1:348-50. 2011
..The effect of this agent against SA and PA biofilms has yet to be reported. Our objective was to determine the in vitro effect of MGO against biofilms of SA and PA, via in vitro testing of MGO against bacterial biofilms...
Polymorphisms in the SERPINA1 (Alpha-1-Antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical therapyShaun J Kilty
The Department of Otolaryngology, Hôpital Hôtel Dieu de Montréal, Universite de Montreal, Montreal, Quebec, Canada
Am J Rhinol Allergy 24:e4-9. 2010
..This implies a potential genetic predisposition to CRS tied to AAT deficiency. The purpose of this study was to investigate the association between single nucleotide polymorphisms (SNPs) in the SERPINA1 gene and CRS...
Are biofilms the answer in the pathophysiology and treatment of chronic rhinosinusitis?Shaun J Kilty
Department of Otolaryngology Head and Neck Surgery, University of Ottawa, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, Ontario K1Y4E9, Canada
Immunol Allergy Clin North Am 29:645-56. 2009
..Novel, minimally invasive methods of testing for the presence of this form of disease will need to become clinically accessible in order for equally innovative therapies to be widely applicable...
The role of bacterial biofilms and the pathophysiology of chronic rhinosinusitisShaun J Kilty
Pavilion Hotel Dieu, 3840, Rue st urbain, Montreal, Quebec, Canada
Curr Allergy Asthma Rep 8:227-33. 2008
..Lastly, directions for contemporary biofilm research are reviewed and highlighted in terms of their application to chronic rhinosinusitis...
Extracranial complications of endoscopic transsphenoidal sellar surgeryShaun J Kilty
Department of Otolaryngology Head and Neck Surgery, University of Ottawa, Ottawa, Ontario
J Otolaryngol Head Neck Surg 39:309-14. 2010
..To be able to critically evaluate all of the outcomes from this approach, the occurrence of any extracranial complications that result from its performance needs to be established...
Treatment alternatives for chronic rhinosinusitis persisting after ESS: what to do when antibiotics, steroids and surgery failMartin Y Desrosiers
The Department of Otolaryngology, Hopital Hotel Dieu, Universite de Montreal, Montreal, Quebec, Canada
Rhinology 46:3-14. 2008
..Management of these individuals remains uncertain, as recent published guidelines on CRS do not extend to this population...