SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cellsBenjamin L Kidder
EMD Serono Research Institute, Inc, Rockland, Massachusetts, USA
Stem Cells 27:317-28. 2009
..Moreover, Brg1 co-occupied a subset of Oct4, Sox2, Nanog, and PcG protein target genes. These results demonstrate an important role for Brg1 in regulating self-renewal and pluripotency in ES cells...
Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenanceBenjamin L Kidder
EMD Serono Research Institute, Inc, Rockland, MA 02370, USA
Genome Res 20:458-72. 2010
..Through genome-wide mapping and global expression analysis of five TF target genes, our data provide a comprehensive analysis of transcriptional networks that regulate TS cell self-renewal...
Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cellsBenjamin L Kidder
EMD Serono Research Institute, Inc, Rockland, Massachusetts, United States of America
PLoS ONE 3:e3932. 2008
..Altogether, we reveal transcriptional targets of two key pluripotency-related genes in ES cells--Stat3 and c-Myc, thus providing further insight into the ES cell transcriptional network...
HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cellsBenjamin L Kidder
EMD Serono Research Institute, Billerica, MA 01821, USA
Nucleic Acids Res 40:2925-39. 2012
..By mapping HDAC1 targets on a global scale, our results describe further insight into epigenetic mechanisms of ES and TS cells self-renewal...