K L Khanduja

Summary

Publications

  1. ncbi request reprint Enhancement in alpha-tocopherol succinate-induced apoptosis by all-trans-retinoic acid in primary leukemic cells: role of antioxidant defense, Bax and c-myc
    K L Khanduja
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 319:133-9. 2008
  2. doi request reprint Corticosteroids affect nitric oxide generation, total free radicals production, and nitric oxide synthase activity in monocytes of asthmatic patients
    Krishan Lal Khanduja
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 346:31-7. 2011
  3. doi request reprint Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats
    A Prakash
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Phytother Res 22:1511-9. 2008
  4. doi request reprint Quercetin impairs the reproductive potential of male mice
    P Ranawat
    Department of Biophysics, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Andrologia 45:56-65. 2013
  5. doi request reprint Changes in antioxidant defense status in response to cisplatin and 5-FU in esophageal carcinoma
    T Kaur
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Dis Esophagus 21:103-7. 2008
  6. doi request reprint Comparative evaluation of different doses of green tea extract alone and in combination with sulfasalazine in experimentally induced inflammatory bowel disease in rats
    D S Prasad Byrav
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Dig Dis Sci 56:1369-78. 2011
  7. doi request reprint Interplay between oncoproteins and antioxidant enzymes in esophageal carcinoma treated without and with chemoradiotherapy: a prospective study
    Tranum Kaur
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Int J Radiat Oncol Biol Phys 70:563-71. 2008
  8. ncbi request reprint Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat
    R S Rao
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh PGIMER, Chandigarh, India
    Eur Neuropsychopharmacol 18:760-7. 2008
  9. ncbi request reprint Low dose gamma-irradiation differentially modulates antioxidant defense in liver and lungs of Balb/c mice
    P K Avti
    Departments of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Int J Radiat Biol 81:901-10. 2005
  10. ncbi request reprint Effect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in rats
    B Medhi
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Indian J Exp Biol 46:583-90. 2008

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Enhancement in alpha-tocopherol succinate-induced apoptosis by all-trans-retinoic acid in primary leukemic cells: role of antioxidant defense, Bax and c-myc
    K L Khanduja
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 319:133-9. 2008
    ..5%, and 52%, respectively. In conclusion, the data reveal that enhancement of alpha-TS-induced apoptosis by ATRA in leukemic cells was through up regulation of Bax and lipid peroxidation, and down regulation of c-myc and GSH...
  2. doi request reprint Corticosteroids affect nitric oxide generation, total free radicals production, and nitric oxide synthase activity in monocytes of asthmatic patients
    Krishan Lal Khanduja
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 346:31-7. 2011
    ..Corticosteroids controlled asthma appears to have association with NOS, NO(•), and TFRA in systemic monocytes of the patients...
  3. doi request reprint Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats
    A Prakash
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Phytother Res 22:1511-9. 2008
    ..The present study indicates that Manuka honey is efficacious in the TNBS-induced rat colitis model, but these results require further confirmation in human studies...
  4. doi request reprint Quercetin impairs the reproductive potential of male mice
    P Ranawat
    Department of Biophysics, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Andrologia 45:56-65. 2013
    ..In conclusion, the deleterious effects of quercetin on germ cells could be attributed to its pro-oxidant ability that might affect the Sertoli cell functions...
  5. doi request reprint Changes in antioxidant defense status in response to cisplatin and 5-FU in esophageal carcinoma
    T Kaur
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Dis Esophagus 21:103-7. 2008
    ..The antioxidant enzymes in the esophageal carcinoma thus may play an important role in influencing the final outcome upon NAT course...
  6. doi request reprint Comparative evaluation of different doses of green tea extract alone and in combination with sulfasalazine in experimentally induced inflammatory bowel disease in rats
    D S Prasad Byrav
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Dig Dis Sci 56:1369-78. 2011
    ..The present study was conducted to evaluate the effect of green tea in experimentally induced inflammatory bowel disease...
  7. doi request reprint Interplay between oncoproteins and antioxidant enzymes in esophageal carcinoma treated without and with chemoradiotherapy: a prospective study
    Tranum Kaur
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Int J Radiat Oncol Biol Phys 70:563-71. 2008
    ..To analyze p53, bcl-2, c-myc, and cyclooxygenase-2 protein expression changes and examine their relationship with various antioxidant enzymes in esophageal carcinoma patients...
  8. ncbi request reprint Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat
    R S Rao
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh PGIMER, Chandigarh, India
    Eur Neuropsychopharmacol 18:760-7. 2008
    ..Cytokines are rapidly induced in the brain after a variety of stimuli including inflammation. Aim of this study was to produce various inflammatory models and seizure to understand the role of TNFalpha in above mentioned models...
  9. ncbi request reprint Low dose gamma-irradiation differentially modulates antioxidant defense in liver and lungs of Balb/c mice
    P K Avti
    Departments of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Int J Radiat Biol 81:901-10. 2005
    ..To evaluate the effect of low-dose (<50 cGy) whole body ?-irradiation on the antioxidant defense system in the liver and the lungs of mice at various post-irradiation intervals...
  10. ncbi request reprint Effect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in rats
    B Medhi
    Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Indian J Exp Biol 46:583-90. 2008
    ..The results indicate the additive effect of Manuka honey with sulfasalazine in colitis...
  11. ncbi request reprint P53, COX-2, iNOS protein expression changes and their relationship with anti-oxidant enzymes in surgically and multi-modality treated esophageal carcinoma patients
    T Kaur
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    J Chemother 18:74-84. 2006
    ..In addition, we observed a negative trend between p53 expression levels and GPx enzyme levels in both the adjoining and tumor tissue of patients having undergone surgery as main mode of treatment...
  12. ncbi request reprint Stable free radical scavenging and antiperoxidative properties of resveratrol compared in vitro with some other bioflavonoids
    K L Khanduja
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Indian J Biochem Biophys 40:416-22. 2003
    ..Antiradical and antiperoxidative activities of resveratrol may explain its beneficial effects in disease states. Assays exhibited no direct correlation between antiradical and antiperoxidative activities of the phenolics...
  13. ncbi request reprint Melatonin treatment is beneficial in pancreatic repair process after experimental acute pancreatitis
    Shabir Sidhu
    Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Eur J Pharmacol 628:282-9. 2010
    ..Results of melatonin group were comparable to that of positive control, CCK-8 group. Thus melatonin treatment was found to promote the spontaneous regeneration process of pancreatic tissue...
  14. ncbi request reprint Resveratrol - an ingredient of red wine abrogates the reproductive capacity in male mice
    P Ranawat
    Department of Biophysics, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Andrologia 46:650-8. 2014
    ..In conclusion, the deleterious effects of resveratrol on germ cells could be attributed to its pro-oxidant ability leading to testicular tissue damage. ..
  15. ncbi request reprint Effect of exposure to domestic cooking fuels on bronchial asthma
    D Behera
    Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012, India
    Indian J Chest Dis Allied Sci 43:27-31. 2001
    ..It was concluded that exposure to biomass fuel and LPG affect pulmonary function (PEFR) in asthmatics and both types of fuels affect the airway function and symptoms of bronchial asthma in a similar manner...
  16. ncbi request reprint Effects of green tea extract on learning, memory, behavior and acetylcholinesterase activity in young and old male rats
    Tranum Kaur
    Department of Biophysics, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Brain Cogn 67:25-30. 2008
    ..To study the effects of green tea extract administration on age-related cognition in young and old male Wistar rats...
  17. ncbi request reprint Impairment of human sperm motility and viability by quercetin is independent of lipid peroxidation
    K L Khanduja
    Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Andrologia 33:277-81. 2001
    ..This inhibition in sperm motility and viability has been linked with decreased Ca2+-ATPase activity, as there was no effect of quercetin on sperm lipid peroxidation...