Yoav Keynan

Summary

Publications

  1. pmc Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    Emerg Infect Dis 16:1621-2. 2010
  2. pmc Immunogenetic factors associated with severe respiratory illness caused by zoonotic H1N1 and H5N1 influenza viruses
    Jennifer Juno
    Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada R3E 0J9
    Clin Dev Immunol 2012:797180. 2012
  3. ncbi request reprint Infective endocarditis in the intensive care unit
    Yoav Keynan
    Department of Internal Medicine, University of Manitoba, Manitoba, Canada Department of Medical Microbiology, University of Manitoba, Manitoba, Canada Department of Community Health Sciences, University of Manitoba, Manitoba, Canada Electronic address
    Crit Care Clin 29:923-51. 2013
  4. pmc Responses to pandemic ASO3-adjuvanted A/California/07/09 H1N1 influenza vaccine in human immunodeficiency virus-infected individuals
    Deborah Kelly
    School of Pharmacy, Memorial University of Newfoundland and Labrador, NL, St John s, Canada
    BMC Immunol 13:49. 2012
  5. doi request reprint The role of polymorphisms in host immune genes in determining the severity of respiratory illness caused by pandemic H1N1 influenza
    Y Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Man, Canada
    Public Health Genomics 16:9-16. 2013
  6. doi request reprint The microbiology of endophthalmitis: global trends and a local perspective
    Y Keynan
    Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Eur J Clin Microbiol Infect Dis 31:2879-86. 2012
  7. ncbi request reprint Pyogenic liver abscess caused by hypermucoviscous Klebsiella pneumoniae
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada
    Scand J Infect Dis 39:828-30. 2007
  8. ncbi request reprint Acremonium vertebral osteomyelitis: molecular diagnosis and response to voriconazole
    Yoav Keynan
    Department of Medicine, Infectious Diseases Unit, Carmel Medical Center, Haifa, Israel
    Clin Infect Dis 45:e5-6. 2007
  9. ncbi request reprint Molecular identification of Exiguobacterium acetylicum as the aetiological agent of bacteraemia
    Yoav Keynan
    Infectious Diseases Unit, Carmel Medical Center, Haifa, Israel
    J Med Microbiol 56:563-4. 2007
  10. ncbi request reprint Bone marrow and skin granulomatosis in a patient with Bartonella infection
    Yoav Keynan
    Department of Internal Medicine, Infectious Disease Unit, Carmel Hospital, Haifa, Israel
    J Med Microbiol 56:133-5. 2007

Collaborators

Detail Information

Publications34

  1. pmc Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    Emerg Infect Dis 16:1621-2. 2010
    ..We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease...
  2. pmc Immunogenetic factors associated with severe respiratory illness caused by zoonotic H1N1 and H5N1 influenza viruses
    Jennifer Juno
    Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada R3E 0J9
    Clin Dev Immunol 2012:797180. 2012
    ..This paper will summarize known immunogenetic factors associated with susceptibility or severity of both pH1N1 and H5N1 infections and will also identify genetic pathways and polymorphisms of high relevance for future study...
  3. ncbi request reprint Infective endocarditis in the intensive care unit
    Yoav Keynan
    Department of Internal Medicine, University of Manitoba, Manitoba, Canada Department of Medical Microbiology, University of Manitoba, Manitoba, Canada Department of Community Health Sciences, University of Manitoba, Manitoba, Canada Electronic address
    Crit Care Clin 29:923-51. 2013
    ..The medical and surgical management of such patients is complex, and timely decisions are important. ..
  4. pmc Responses to pandemic ASO3-adjuvanted A/California/07/09 H1N1 influenza vaccine in human immunodeficiency virus-infected individuals
    Deborah Kelly
    School of Pharmacy, Memorial University of Newfoundland and Labrador, NL, St John s, Canada
    BMC Immunol 13:49. 2012
    ....
  5. doi request reprint The role of polymorphisms in host immune genes in determining the severity of respiratory illness caused by pandemic H1N1 influenza
    Y Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Man, Canada
    Public Health Genomics 16:9-16. 2013
    ..We will focus on novel and key insights gained through study of ethnic populations that appeared more vulnerable to severe disease during the 2009 H1N1 pandemic...
  6. doi request reprint The microbiology of endophthalmitis: global trends and a local perspective
    Y Keynan
    Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
    Eur J Clin Microbiol Infect Dis 31:2879-86. 2012
    ..Gram-positive bacteria with coagulase-negative staphylococci are the most common causative organisms, reflecting the association with surgical procedures...
  7. ncbi request reprint Pyogenic liver abscess caused by hypermucoviscous Klebsiella pneumoniae
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada
    Scand J Infect Dis 39:828-30. 2007
    ..We describe a case of PLA caused by the hypermucoviscous, K1 capsular serotype of Klebsiella pneumoniae in a Canadian man and highlight the unique features of this increasingly common cause of liver abscess...
  8. ncbi request reprint Acremonium vertebral osteomyelitis: molecular diagnosis and response to voriconazole
    Yoav Keynan
    Department of Medicine, Infectious Diseases Unit, Carmel Medical Center, Haifa, Israel
    Clin Infect Dis 45:e5-6. 2007
    ..The report highlights the role of molecular diagnosis of rare fungal osteomyelitis. The patient was successfully treated with voriconazole...
  9. ncbi request reprint Molecular identification of Exiguobacterium acetylicum as the aetiological agent of bacteraemia
    Yoav Keynan
    Infectious Diseases Unit, Carmel Medical Center, Haifa, Israel
    J Med Microbiol 56:563-4. 2007
    ..The availability of sequence-based methods facilitated rapid identification and expanded the spectrum of diseases attributed to coryneform bacteria and specifically to the genus Exiguobacterium...
  10. ncbi request reprint Bone marrow and skin granulomatosis in a patient with Bartonella infection
    Yoav Keynan
    Department of Internal Medicine, Infectious Disease Unit, Carmel Hospital, Haifa, Israel
    J Med Microbiol 56:133-5. 2007
    ..The clinical presentation included prolonged fever, pancytopenia, rash and hepatitis. Bartonella infection should thus be added to the growing list of entities that produce marrow granulomas and fever...
  11. ncbi request reprint Hyperbaric therapy for bilateral visual loss during hemodialysis
    Yoav Keynan
    Israel Naval Medical Institute, Israel Defence Forces Medical Corps, Haifa, Israel
    Clin Exp Nephrol 10:82-4. 2006
    ..Hyperbaric treatment should be considered, where early administration is possible, for bilateral blindness during hemodialysis...
  12. ncbi request reprint Hyperbaric oxygen in the treatment of sudden deafness
    Liran Domachevsky
    Israel Naval Medical Institute, IDF Medical Corps, P O Box 8040, 31 080, Haifa, Israel
    Eur Arch Otorhinolaryngol 264:951-3. 2007
    ..The pathogenesis of SD may involve a reduction in cochlear blood flow and perilymph oxygenation, making early HBOT a reasonable treatment modality for this condition...
  13. ncbi request reprint Vancomycin-resistant enterococci
    Ethan Rubinstein
    Section of Infectious Diseases, Department of Internal Medicine and Medical Microbiology, University of Manitoba, 543 645 Bannatyne Ave, Basic Medical Building, Winnipeg, Manitoba R3E 0J9, Canada Electronic address
    Crit Care Clin 29:841-52. 2013
    ..Most severe VRE infections will need combination therapy because many of the effective antimicrobial agents, when used alone, have only a bacteriostatic effect...
  14. doi request reprint Are drug clinical trials broadly applicable? The case of staphylococcal bacteraemia
    Yoav Keynan
    Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada
    Int J Antimicrob Agents 34:S35-7. 2009
    ..We chose to evaluate the applicability to general staphylococcal bacteraemia patient populations of clinical trials comparing antimicrobial agents used to treat Staphylococcus aureus bacteraemia...
  15. doi request reprint Staphylococcus aureus bacteremia, risk factors, complications, and management
    Yoav Keynan
    Section of Infectious Diseases, Department of Internal Medicine and Medical Microbiology, University of Manitoba, 543 745 Bannatyne Ave, Basic Sciences Bldg, Manitoba R3E 0J9, Canada
    Crit Care Clin 29:547-62. 2013
    ..The infection is often complicated with several sites of metastatic foci and is nosocomial frequently. New antibiotics to fight MRSA have been introduced and are equivalent or better than vancomycin. ..
  16. doi request reprint HIV controllers are distinguished by chemokine expression profile and HIV-specific T-cell proliferative potential
    Catherine M Card
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada
    J Acquir Immune Defic Syndr 59:427-37. 2012
    ..We performed a comprehensive evaluation of inflammation and T-cell activation in a demographically unique cohort of HIV controllers and noncontrollers...
  17. ncbi request reprint The changing face of Klebsiella pneumoniae infections in the community
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada
    Int J Antimicrob Agents 30:385-9. 2007
    ..In this review we will discuss these two Kp emerging trends...
  18. ncbi request reprint Swimming-induced pulmonary edema: clinical presentation and serial lung function
    Yochai Adir
    IDF Medical Corps, Israel Naval Medical Institute, Haifa
    Chest 126:394-9. 2004
    ..We also report the results of forced spirometry in a subgroup of 37 swimmers...
  19. pmc Invariant NKT cells: regulation and function during viral infection
    Jennifer A Juno
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
    PLoS Pathog 8:e1002838. 2012
    ..We will also highlight recent efforts to harness iNKT ligands as vaccine adjuvants capable of improving vaccination-induced cellular immune responses...
  20. ncbi request reprint Hyperbaric oxygen in the treatment of carbon monoxide poisoning
    Liran Domachevsky
    IDF Medical Corps, Israel Naval Medical Institute, Haifa, Israel
    Clin Toxicol (Phila) 43:181-8. 2005
    ..In the present review, we discuss the conclusions of four randomized controlled studies and propose a hyperbaric oxygen treatment protocol based on these conclusions...
  21. doi request reprint Short-course therapy for severe infections
    Ethan Rubinstein
    Section of Infectious Diseases, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Int J Antimicrob Agents 42:S22-4. 2013
    ..The benefits of short-duration therapy are obvious and may contribute to halting resistance, reduced costs and rational patient management...
  22. pmc Estimated cumulative incidence of pandemic (H1N1) influenza among pregnant women during the first wave of the 2009 pandemic
    Salaheddin M Mahmud
    Department of Community Health Sciences, University of Manitoba, Winnipeg, Man
    CMAJ 182:1522-4. 2010
    ..We estimated the cumulative incidence of pandemic (H1N1) influenza among pregnant women in the province of Manitoba during the first wave of the 2009 pandemic...
  23. doi request reprint Altered dendritic cell-natural killer interaction in Kenyan sex workers resistant to HIV-1 infection
    Hormas Ghadially
    The Lautenberg Center for General and Tumor Immunology, The Hebrew University Hadassah Medical School, Jerusalem, Israel
    AIDS 26:429-36. 2012
    ..They are also involved in the regulation of adaptive immune responses through cytokine secretion and the interaction with antigen-presenting cells. However, their role in HIV infection is only partially understood...
  24. ncbi request reprint Underwater hearing and sound localization with and without an air interface
    Avi Shupak
    Israel Naval Medical Institute, Haifa, Israel
    Otol Neurotol 26:127-30. 2005
    ..Underwater hearing acuity and sound localization are improved by the presence of an air interface around the pinnae and inside the external ear canals...
  25. doi request reprint Quinolones for mycobacterial infections
    Ethan Rubinstein
    Department of Internal Medicine and Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada
    Int J Antimicrob Agents 42:1-4. 2013
    ..The place of the newly developed FQ-related diarylquinoline compound known as bedaquiline in the treatment of drug-resistant TB is unclear; however, human studies suggest that it might be effective for this indication. ..
  26. pmc Legionella pneumophila serotype 1 pneumonia in patient receiving adalimumab
    Terry C Wuerz
    University of Manitoba, Winnipeg, Manitoba, Canada
    Emerg Infect Dis 18:1872-4. 2012
    ..As use of tumor necrosis factor-α inhibitors increase, clinicians should consider their possible association with legionellosis...
  27. ncbi request reprint Epidermodysplasia verruciformis in an HIV-infected man: a case report and review of the literature
    Amit Kaushal
    University of Manitoba, Winnipeg, Canada
    Top Antivir Med 20:173-9. 2012
    ....
  28. pmc Evaluation of influenza-specific humoral response by microbead array analysis
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba
    Can J Infect Dis Med Microbiol 22:25-9. 2011
    ..The benefits of suspension microbead array (MBA) analysis are numerous. The multiplex capabilities of the system conserve time, money and sample, while generating statistically powerful data...
  29. doi request reprint The role of regulatory T cells in chronic and acute viral infections
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada
    Clin Infect Dis 46:1046-52. 2008
    ....
  30. pmc Use of oral miltefosine for cutaneous leishmaniasis in Canadian soldiers returning from Afghanistan
    Yoav Keynan
    Departments of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba
    Can J Infect Dis Med Microbiol 19:394-6. 2008
    ..Their lesions did not improve with fluconazole therapy, and the organism demonstrated in vitro resistance. Oral miltefosine seemed effective...
  31. ncbi request reprint Identification of two novel HLA-C alleles, Cw*070105 and Cw*1408, from East African women
    Yoav Keynan
    Department of Medical Microbiology, University of Manitoba, 730 William Avenue, Winnipeg, Manitoba, Canada
    Hum Immunol 67:359-62. 2006
    ..The second new allele is identical to Cw*1403 except for a nonsynonomous change at codon 21 (CAC-->CGC), changed from histidine to arginine. The new allele has been named by the WHO nomenclature committee as Cw*1408...
  32. ncbi request reprint Pulmonary edema following closed-circuit oxygen diving and strenuous swimming
    Avi Shupak
    Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel
    Aviat Space Environ Med 74:1201-4. 2003
    ..Diving-induced pulmonary edema should be included in the differential diagnosis of acute hypoxemia, sometimes accompanied by acid-base abnormalities, when this is seen in a diver...
  33. pmc Capsular polysaccharide synthesis regions in Klebsiella pneumoniae serotype K57 and a new capsular serotype
    Yi Jiun Pan
    Department of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan
    J Clin Microbiol 46:2231-40. 2008
    ..We conclude that sequences from these two cps regions are very useful in detecting K57 and the new cps genotype...
  34. ncbi request reprint Diabetes mellitus and pyogenic liver abscess: risk and prognosis
    Yoav Keynan
    Clin Infect Dis 45:801. 2007