Research Topics
| Robert W SnowSummaryAffiliation: Kenya Medical Research Institute Country: Kenya Publications
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Detail Information
Publications
The global distribution of clinical episodes of Plasmodium falciparum malariaRobert W Snow
Public Health Group, KEMRI Wellcome Trust Research Laboratories PO Box 43640, 00100 Nairobi, Kenya
Nature 434:214-7. 2005..Without an informed understanding of the cartography of malaria risk, the global extent of clinical disease caused by P. falciparum will continue to be underestimated...
Pediatric mortality in Africa: plasmodium falciparum malaria as a cause or risk?Robert W Snow
Kenya Medical Research Institute Wellcome Trust Collaborative Program, Nairobi, Kenya
Am J Trop Med Hyg 71:16-24. 2004..In conclusion, the disability and death burden due to malaria in African children could be higher than that detectable from cause-specific DALY estimations...
Estimating the needs for artesunate-based combination therapy for malaria case-management in AfricaRobert W Snow
KEMRI Wellcome Trust Collaborative Program, PO Box 43640, Nairobi, Kenya
Trends Parasitol 19:363-9. 2003..Better diagnostics would also be an important consideration for a new ACT policy in Africa...
The risks of malaria infection in Kenya in 2009Abdisalan M Noor
Centre for Geographic Medicine, KEMRI University of Oxford, Kenyatta National Hospital Grounds, Nairobi, Kenya
BMC Infect Dis 9:180. 2009..Here we present a new map of malaria risk for Kenya in 2009...
A world malaria map: Plasmodium falciparum endemicity in 2007Simon I Hay
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute University of Oxford Wellcome TrustCollaborative Programme, Nairobi, Kenya
PLoS Med 6:e1000048. 2009..It is exactly 40 y since the last global map of malaria endemicity was published. This paper describes the generation of a new world map of Plasmodium falciparum malaria endemicity for the year 2007...
The use of artemether-lumefantrine by febrile children following national implementation of a revised drug policy in KenyaCaroline W Gitonga
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Nairobi, Kenya
Trop Med Int Health 13:487-94. 2008..To examine access to, timing and use of artemisinin-based combination therapy among rural Kenyan febrile children before and following the introduction of artemether-lumefantrine (AL) as first-line antimalarial drug policy...
The effect of mobile phone text-message reminders on Kenyan health workers' adherence to malaria treatment guidelines: a cluster randomised trialDejan Zurovac
Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Lancet 378:795-803. 2011..We assessed whether text-message reminders sent to health workers' mobile phones could improve and maintain their adherence to treatment guidelines for outpatient paediatric malaria in Kenya...
Access and barriers to measures targeted to prevent malaria in pregnancy in rural KenyaPriscilla W Gikandi
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Trop Med Int Health 13:208-17. 2008....
Spatial modelling of healthcare utilisation for treatment of fever in NamibiaVictor A Alegana
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, PO Box 43640, 00100 GPO Nairobi, Kenya
Int J Health Geogr 11:6. 2012..Here, empirical household survey data on treatment seeking for fever were used to model the utilisation of public health facilities and define their catchment areas and populations in northern Namibia...
The spatial-temporal clustering of Plasmodium falciparum infection over eleven years in Gezira State, The SudanSamia E Mirghani
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI University of Oxford Wellcome Trust Collaborative Programme, Kenyatta National Hospital Grounds, Nairobi, Kenya
Malar J 9:172. 2010..Here, the space-time clustering of Plasmodium falciparum infections using data from repeat cross-sectional surveys in Gezira State, a low transmission area in northern Sudan, is investigated...
Increasing coverage and decreasing inequity in insecticide-treated bed net use among rural Kenyan childrenAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
PLoS Med 4:e255. 2007..In this study, we present repeat observations of ITN coverage among rural Kenyan homesteads exposed at different times to a range of delivery models, and assess changes in coverage across socioeconomic groups...
The challenges of changing national malaria drug policy to artemisinin-based combinations in KenyaAbdinasir A Amin
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Malar J 6:72. 2007....
Paediatric malaria case-management with artemether-lumefantrine in Zambia: a repeat cross-sectional studyDejan Zurovac
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI Wellcome Trust Collaborative Programme, Nairobi, Kenya
Malar J 6:31. 2007..Improvements in the case-management of uncomplicated malaria two years after the initial evaluation and three years after the change of policy in Zambia are reported...
The magnitude and trend of artemether-lumefantrine stock-outs at public health facilities in KenyaRaymond K Sudoi
Malaria Public Health and Epidemiology Group, KEMRI Wellcome Trust Research Programme, PO Box 43640, 00100 GPO Nairobi, Kenya
Malar J 11:37. 2012..Here, 2010-2011 data are reported from public facilities in Kenya where alarming stock-outs were revealed in 2008...
Why don't health workers prescribe ACT? A qualitative study of factors affecting the prescription of artemether-lumefantrineBeatrice Wasunna
Eastern and Southern Africa Centre of International Parasite Control ESACIPAC KEMRI, P O Box 54840 00200, Nairobi, Kenya
Malar J 7:29. 2008..New national guidelines on the diagnosis, treatment and prevention were developed and disseminated to health workers together with in-service training...
Health worker performance in the management of paediatric fevers following in-service training and exposure to job aids in KenyaBeatrice Wasunna
Malaria Public Health and Epidemiology Group, KEMRI Wellcome Trust Research Programme, Centre for Geographic Medicine Research Coast CGMRC, Nairobi, Kenya Nairobi, Kenya
Malar J 9:261. 2010..In 2007, a new initiative was launched in one part of Kenya to improve malaria case-management through enhanced in-service training and provision of job aids...
Spatial prediction of Plasmodium falciparum prevalence in SomaliaAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, P O Box 43640, 00100 GPO, Nairobi, Kenya
Malar J 7:159. 2008..There is a lack of reliable contemporary malaria maps in endemic countries in sub-Saharan Africa. This problem is particularly acute in low malaria transmission countries such as those located in the horn of Africa...
Promoting the social value of research in Kenya: examining the practical aspects of collaborative partnerships using an ethical frameworkGeoffrey Mbaabu Lairumbi
Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast, Wellcome Trust Research Programme, P O Box 43640, Nairobi, Kenya
Soc Sci Med 67:734-47. 2008....
Health service providers in Somalia: their readiness to provide malaria case-managementAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI, Wellcome Trust Research Programme, Nairobi, Kenya
Malar J 8:100. 2009..The readiness of the public health sector to provide malaria case-management in Somalia, a country where there has been no functioning central government for almost two decades, was investigated...
Age patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensityEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI Wellcome Trust Collaborative Programme, Kenyatta National Hospital Grounds PO Box 43640 00100, Nairobi, Kenya
Malar J 8:4. 2009....
Plasmodium infection, anaemia and mosquito net use among school children across different settings in KenyaCaroline W Gitonga
Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Trop Med Int Health 17:858-70. 2012..To investigate risk factors, including reported net use, for Plasmodium infection and anaemia among school children and to explore variations in effects across different malaria ecologies occurring in Kenya...
The changing limits and incidence of malaria in Africa: 1939-2009Robert W Snow
Malaria Public Health and Epidemiology Group, KEMRI Wellcome Trust Collaborative Programme, Nairobi, Kenya
Adv Parasitol 78:169-262. 2012..One result is a more informed mapped definition of the changing margins of transmission in 1939, 1959, 1979, 1999 and 2009...
Progress towards implementation of ACT malaria case-management in public health facilities in the Republic of Sudan: a cluster-sample surveyTarig M Abdelgader
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
BMC Public Health 12:11. 2012..Three years after the launch of the strategy a health facility survey was undertaken to evaluate case-management practices and readiness of the health facilities and health workers to implement a new malaria case-management strategy...
Insecticide-treated net coverage in Africa: mapping progress in 2000-07Abdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI University of Oxford Wellcome Trust Collaborative Programme, Nairobi, Kenya
Lancet 373:58-67. 2009..We gathered subnational ITN coverage sample survey data from 40 malaria-endemic countries in Africa between 2000 and 2007...
The limits and intensity of Plasmodium falciparum transmission: implications for malaria control and elimination worldwideCarlos A Guerra
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenyan Medical Research Institute University of Oxford Wellcome Trust Collaborative Programme, Nairobi, Kenya
PLoS Med 5:e38. 2008..This paper aims to define the global geographic distribution of P. falciparum malaria in 2007 and to provide a preliminary description of its transmission intensity within this range...
International funding for malaria control in relation to populations at risk of stable Plasmodium falciparum transmissionRobert W Snow
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenyan Medical Research Institute, University of Oxford, Wellcome Trust Collaborative Programme, Nairobi, Kenya
PLoS Med 5:e142. 2008..To examine this relationship, we compare an audit of international commitments with an objective assessment of national need: the population at risk of stable Plasmodium falciparum malaria transmission in 2007...
Malaria paediatric hospitalization between 1999 and 2008 across KenyaEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, P O Box 43640, 00100 GPO, Nairobi, Kenya
BMC Med 7:75. 2009..Here we present a nationwide assessment of changes over 10 years in paediatric malaria hospitalization across Kenya...
Equity and adequacy of international donor assistance for global malaria control: an analysis of populations at risk and external funding commitmentsRobert W Snow
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute, Nairobi, Kenya
Lancet 376:1409-16. 2010..We aimed to identify the unmet financial needs that would be biologically and economically equitable and would increase the chances of reaching worldwide malaria-control ambitions...
The use of mosquito nets and the prevalence of Plasmodium falciparum infection in rural South Central SomaliaAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
PLoS ONE 3:e2081. 2008..Little is known, however, on the effectiveness of ITN in areas of Africa that support low transmission. This hinders the accurate estimation of impact of ITN use on disease burden and its cost-effectiveness in low transmission settings...
The clinical burden of malaria in Nairobi: a historical review and contemporary auditSandra A Mudhune
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, PO Box 43640, 00100 GPO Nairobi, Kenya
Malar J 10:138. 2011..This paper presents a combined historical and contemporary review of the clinical burden of malaria within one of Africa's largest urban settlements, Nairobi, Kenya...
Malaria case-management under artemether-lumefantrine treatment policy in UgandaDejan Zurovac
Malaria Public Health and Epidemiology Group, KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
Malar J 7:181. 2008..Here the quality of AL case-management is reported from Uganda; approximately one year after AL replaced combination of chloroquine and sulphadoxine-pyrimethamine (CQ+SP) as recommended first line treatment for uncomplicated malaria...
Predicting the unmet need for biologically targeted coverage of insecticide-treated nets in KenyaAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute University of Oxford Wellcome Trust Research Programme, Kenyatta National Hospital Grounds, Nairobi, Kenya
Am J Trop Med Hyg 83:854-60. 2010..4 to 18.1 million nets if not restricted to areas of greatest malaria risk. In Kenya, this evidence-based approach could save the national program at least 55 million US dollars...
Reconciling national treatment policies and drug regulation in KenyaAbdinasir A Amin
Centre for Geographic Medicine Research-Coast, Kenya Medical Research Institute/Wellcome Trust Collaborative Programme, P.O. Box 43640, Nairobi, 00100 GPO, Kenya
Health Policy Plan 22:111-2. 2007
Implementing school malaria surveys in Kenya: towards a national surveillance systemCaroline W Gitonga
Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Malar J 9:306. 2010..To design and implement surveys of malaria infection and coverage of malaria control interventions among school children in Kenya in order to contribute towards a nationwide assessment of malaria...
The relationship between reported fever and Plasmodium falciparum infection in African childrenEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, PO Box 43640, 00100 GPO, Nairobi, Kenya
Malar J 9:99. 2010....
Modelling distances travelled to government health services in KenyaAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Laboratories, Nairobi, Kenya
Trop Med Int Health 11:188-96. 2006..To systematically evaluate descriptive measures of spatial access to medical treatment, as part of the millennium development goals to reduce the burden of HIV/AIDS, tuberculosis and malaria...
Changing malaria intervention coverage, transmission and hospitalization in KenyaEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, 00100 GPO, Nairobi, Kenya
Malar J 9:285. 2010..Whether this transition is directly related to the scaling of intervention coverage remains a moot point...
Wealth, mother's education and physical access as determinants of retail sector net use in rural KenyaAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute, PO Box 43640, 00100, Nairobi, Kenya
Malar J 5:5. 2006..The influence of homestead wealth on use of nets purchased from the retail sector is well documented, however, the competing influence of mother's education and physical access to net providers is less well understood...
Effect of expanded insecticide-treated bednet coverage on child survival in rural Kenya: a longitudinal studyGreg W Fegan
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Lancet 370:1035-9. 2007..ITN coverage has increased rapidly in Kenya from 7% in 2004 to 67% in 2006. We aimed to assess the extent to which this investment has led to improvements in child survival...
Distribution of the main malaria vectors in KenyaRobi M Okara
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI University of Oxford Wellcome Trust Collaborative Programme, Kenyatta National Hospital Grounds, PO Box 43640 00100, Nairobi, Kenya
Malar J 9:69. 2010..The methods and approaches used to assemble contemporary available data on the present distribution of the dominant malaria vectors in Kenya are presented here...
Modeling the financial and clinical implications of malaria rapid diagnostic tests in the case-management of older children and adults in KenyaDejan Zurovac
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Am J Trop Med Hyg 78:884-91. 2008..In both districts, adherence to revised clinical practices with RDTs has the potential to further decrease treatment errors with acceptable costs...
Fever treatment in the absence of malaria transmission in an urban informal settlement in Nairobi, KenyaYazoume Ye
African Population and Health Research Centre, Nairobi, Kenya
Malar J 8:160. 2009..This paper presents the results of an investigation into infection prevalence and treatment of recent febrile events among a slum population in Nairobi, Kenya...
The decline in paediatric malaria admissions on the coast of KenyaEmelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, P, O, Box 43640, 00100 GPO, Nairobi, Kenya
Malar J 6:151. 2007..There is only limited information on the health impact of expanded coverage of malaria control and preventative strategies in Africa...
The difference between effectiveness and efficacy of antimalarial drugs in KenyaAbdinasir A Amin
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Nairobi, Kenya
Trop Med Int Health 9:967-74. 2004..To demonstrate the difference between effectiveness and efficacy of antimalarial (AM) drugs in Kenya...
Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?Mike English
KEMRI Wellcome Trust Programme, Centre for Geographic Medicine Research Coast, Nairobi, Kenya
PLoS Med 6:e1000015. 2009....
The use of schools for malaria surveillance and programme evaluation in AfricaSimon Brooker
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Malar J 8:231. 2009..Finally, areas requiring further investigation are highlighted...
Plasmodium-helminth coinfection and its sources of heterogeneity across East AfricaSimon J Brooker
Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
J Infect Dis 205:841-52. 2012..This study investigates the distribution and heterogeneity of coinfection with Plasmodium falciparum and 3 major helminth species across East Africa...
The relationship between the Plasmodium falciparum parasite ratio in childhood and climate estimates of malaria transmission in KenyaJudith A Omumbo
Public Health Group, KEMRI Wellcome Trust Research Laboratories P, O, Box 43640, 00100 GPO, Nairobi, Kenya
Malar J 3:17. 2004....
Brands, costs and registration status of antimalarial drugs in the Kenyan retail sectorAbdinasir A Amin
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute Wellcome Trust Collaborative Programme, P O Box 43640, Nairobi, 00100 GPO, Kenya
Malar J 4:36. 2005..This study aimed to assess the range, costs, sources and registration of antimalarial drugs in the Kenyan retail sector...
The management of fevers in Kenyan children and adults in an area of seasonal malaria transmissionHelen L Guyatt
KEMRI Wellcome Trust Collaborative Programme, GPO 00100, Nairobi, PO Box 43640, Kenya
Trans R Soc Trop Med Hyg 98:111-5. 2004..In light of the proposed new, more costly anti-malarial drug combinations these findings have major implications for the effective allocation of limited financial resources at household and government levels...
Operational strategies to achieve and maintain malaria eliminationBruno Moonen
Clinton Health Access Initiative, Nairobi, Kenya
Lancet 376:1592-603. 2010..Elimination will thus additionally need identification and treatment of incoming infections before they lead to transmission, or, more realistically, embarking on regional initiatives to dry up importation at its source...
Increasing malaria hospital admissions in Uganda between 1999 and 2009Emelda A Okiro
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
BMC Med 9:37. 2011..Less well described are changing patterns of malaria burden in areas of high parasite transmission and slower increases in control and treatment access...
A spatial national health facility database for public health sector planning in Kenya in 2008Abdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI, University of Oxford, Wellcome Trust Collaborative Programme, Kenyatta National Hospital Grounds behind NASCOP, Nairobi, Kenya
Int J Health Geogr 8:13. 2009..The spatial referencing of service providers to allow their representation in a geographic information system is vital if the full planning potential of such data is to be realized...
The malaria Atlas Project: developing global maps of malaria riskSimon I Hay
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical ResearchInstitute, Nairobi, Kenya
PLoS Med 3:e473. 2006
Measuring malaria endemicity from intense to interrupted transmissionSimon I Hay
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute University of Oxford Wellcome Trust Collaborative Programme, Nairobi, Kenya
Lancet Infect Dis 8:369-78. 2008..These considerations are also important to an international community that has recently been challenged to revaluate the prospects for malaria eradication...
Using remotely sensed night-time light as a proxy for poverty in AfricaAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI University of Oxford Wellcome Trust Collaborative Programme, Kenyatta National Hospital Grounds behind NASCOP, P, O, Box 43640 00100, Nairobi, Kenya
Popul Health Metr 6:5. 2008..Remotely sensed data on artificial night time lights (NTL) have been shown to correlate with gross domestic product in developed countries...
Treatment of paediatric malaria during a period of drug transition to artemether-lumefantrine in Zambia: cross sectional studyDejan Zurovac
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI Wellcome Trust Collaborative Programme, PO Box 43640, 00100 GPO, Nairobi, Kenya
BMJ 331:734. 2005..To evaluate treatment practices for uncomplicated malaria after the policy change from chloroquine to sulfadoxine-pyrimethamine and to artemether-lumefantrine in Zambia...
Malaria in Kenya's western highlandsG Dennis Shanks
US Army Medical Research Unit-Kenya, Nairobi, Kenya
Emerg Infect Dis 11:1425-32. 2005..Antimalarial drugs can limit the pool of gametocytes available to infect mosquitoes during the brief transmission season...
Clinical algorithms for malaria diagnosis lack utility among people of different age groupsTabitha W Mwangi
Kenya Medical Research Institute, CGMRC Wellcome Trust Collaborative Program, Kilifi, Kenya
Trop Med Int Health 10:530-6. 2005....
Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseasesThomas N Williams
Kenya Medical Research Institute Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi District Hospital, Kilifi, Kenya
J Infect Dis 192:178-86. 2005..Nevertheless, >50 years after this hypothesis was first proposed, the epidemiological description of the relationships between HbAS, malaria, and other common causes of child mortality remains incomplete...
Case definitions of clinical malaria under different transmission conditions in Kilifi District, KenyaTabitha W Mwangi
Kenya Medical Research Institute, Centre for Geographic Medicine Research Coast Wellcome Trust Collaborative Program, Kenya
J Infect Dis 191:1932-9. 2005..We defined and quantified cases of malaria in people of different age groups from 2 areas with different rates of transmission of malaria...
Malaria prevention in highland Kenya: indoor residual house-spraying vs. insecticide-treated bednetsHelen L Guyatt
Wellcome Trust Research Laboratories KEMRI, Nairobi, Kenya
Trop Med Int Health 7:298-303. 2002..This study suggests that IRS may be both more effective and cheaper than ITNs in communities subjected to low, seasonal risks of infection and as such should be considered as part of the control armamentarium for malaria prevention...
Negative epistasis between the malaria-protective effects of alpha+-thalassemia and the sickle cell traitThomas N Williams
Kenya Medical Research Institute Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, PO Box 230, Kilifi District Hospital, Kilifi, Kenya
Nat Genet 37:1253-7. 2005..Negative epistasis could explain the failure of alpha(+)-thalassemia to reach fixation in any population in sub-Saharan Africa...
The effects of untreated bednets on malaria infection and morbidity on the Kenyan coastTabitha W Mwangi
Kenya Medical Research Institute, CGMRC Wellcome Trust Collaborative Programme, PO Box 230, Kilifi, Kenya
Trans R Soc Trop Med Hyg 97:369-72. 2003..In the face of persistent failure of communities to take up net retreatment, there is hope that untreated nets will offer some protection against malaria infection and disease compared with not using nets at all...
Free bednets to pregnant women through antenatal clinics in Kenya: a cheap, simple and equitable approach to deliveryHelen L Guyatt
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Nairobi, Kenya
Trop Med Int Health 7:409-20. 2002....
Too poor to pay: charging for insecticide-treated bednets in highland KenyaHelen L Guyatt
Wellcome Trust Research Laboratories KEMRI, Nairobi, Kenya
Trop Med Int Health 7:846-50. 2002..One option to have an immediate equitable impact on ITN coverage and break the cycle between malaria and poverty is to provide this service free of charge...
Delivery of paediatric care at the first-referral level in KenyaMike English
KEMRI Centre for Geographic Medicine Research Coast, PO Box 230, Kilifi, Kenya
Lancet 364:1622-9. 2004..The capacity of the district hospital in Kenya needs strengthening by comprehensive policies that address real needs if current or new interventions and services at this level of care are to enhance child survival...
Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in KenyaMike English
KEMRI Centre for Geographic Medicine Research, PO Box 230, Kilifi, Kenya
Lancet 363:1948-53. 2004..The district hospital is considered essential for delivering basic, cost-effective health care to children in resource poor countries. We aimed to investigate the performance of these facilities in Kenya...
An immune basis for malaria protection by the sickle cell traitThomas N Williams
Kenya Medical Research Institute, Wellcome Trust Programme, Centre for Geographic Medicine Research, Coast, Kilifi District Hospital, Kilifi, Kenya
PLoS Med 2:e128. 2005....
The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan AfricaVictor Mung'ala-Odera
Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
Am J Trop Med Hyg 71:64-70. 2004..The figure is likely to be considerably higher, since these estimates do not include neurocognitive impairment following non-cerebral malaria in children or adults in stable endemic areas, or populations in low stable or epidemic areas...
The cost of not treating bednetsHelen L Guyatt
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, PO Box 43640, Kenyatta National Hospital, Nairobi, Kenya
Trends Parasitol 18:12-6. 2002..The evidence for a protective effect of untreated nets against malaria is presented here alongside an analysis of how well untreated nets would need to work in order to compete with treated nets within a cost-effectiveness framework...
The use of insecticide treated nets by age: implications for universal coverage in AfricaAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, KEMRI University of Oxford Wellcome Trust Collaborative Programme, Kenyatta National Hospital Grounds, Nairobi, Kenya
BMC Public Health 9:369. 2009..Here we examine the age pattern of use of insecticide treated nets (ITNs) in Africa in relation to biological vulnerabilities and the implications for future prospects for universal coverage...
Establishing the extent of malaria transmission and challenges facing pre-elimination in the Republic of DjiboutiAbdisalan M Noor
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute Wellcome Trust Research Programme, P O Box 43640, 00100 GPO, Nairobi, Kenya
BMC Infect Dis 11:121. 2011....
Mobile phone text messaging: tool for malaria control in AfricaDejan Zurovac
Malaria Public Health and Epidemiology Group, Kenya Medical Research Institute Wellcome Trust Research Program, Nairobi, Kenya
PLoS Med 9:e1001176. 2012..Dejan Zurovac and colleagues discuss six areas where text messaging could improve the delivery of health services and health outcomes in malaria in Africa...
The use of formal and informal curative services in the management of paediatric fevers in four districts in KenyaAbdinasir A Amin
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, Nairobi, Kenya
Trop Med Int Health 8:1143-52. 2003..To assess the sources, costs, timing and types of treatment for fevers among children under 5 years of age in four ecologically distinct districts of Kenya...
Impact of malaria during pregnancy on low birth weight in sub-Saharan AfricaHelen L Guyatt
Kenya Medical Research Institute Wellcome Trust Collaborative Programme, P O Box 43640, Nairobi, Kenya
Clin Microbiol Rev 17:760-9, table of contents. 2004..These estimates imply that around 100,000 infant deaths each year could be due to LBW caused by malaria during pregnancy in areas of malaria endemicity in Africa...
Iron and folic acid supplementation and malaria riskMike English
Kenya Medical Research Institute/Wellcome Trust Collaborative Programme, Nairobi, Kenya
Lancet 367:90-1. 2006
Comparing methods of estimating the global morbidity burden from Plasmodium falciparum malariaRobert W Snow
Malaria Public Health and Epidemiology Group, Centre for Geographic Medicine, Kenya Medical Research Institute, Nairobi, Kenya
Am J Trop Med Hyg 74:189-90. 2006
Plasmodium falciparum infections are associated with agglutinating antibodies to parasite-infected erythrocyte surface antigens among healthy Kenyan childrenPeter C Bull
Kenya Medical Research Insitute KEMRI Centre for Geographic Medicine Research, Coast, Kilifi, Kenya
J Infect Dis 185:1688-91. 2002....
Defining and detecting malaria epidemics in the highlands of western KenyaSimon I Hay
Department of Zoology, University of Oxford, Oxford, United Kingdom
Emerg Infect Dis 8:555-62. 2002..The performance of these methods is discussed and comments made about their appropriateness for the highlands of western Kenya...
Clinical status and implications of antimalarial drug resistancePeter A Winstanley
Department of Pharmacology and Therapeutics, University of Liverpool, L69 3GE, Liverpool, UK
Microbes Infect 4:157-64. 2002..Artemisinin combination therapy may offer considerable advantages over alternative therapies, but its introduction faces considerable logistic difficulty...
Climate change and the resurgence of malaria in the East African highlandsSimon I Hay
TALA Research Group, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Nature 415:905-9. 2002..A high degree of temporal and spatial variation in the climate of East Africa suggests further that claimed associations between local malaria resurgences and regional changes in climate are overly simplistic...
Clinical epidemiology of malaria in the highlands of western KenyaSimon I Hay
Department of Zoology, University of Oxford, Oxford, UK
Emerg Infect Dis 8:543-8. 2002..The malaria of the region is best described as seasonal and meso-endemic. We discuss the implications for malaria control options in the Kenyan highlands...
Hot topic or hot air? Climate change and malaria resurgence in East African highlandsSimon I Hay
Dept of Zoology, University of Oxford, UK
Trends Parasitol 18:530-4. 2002..We find the widespread increase in resistance of the malaria parasite to drugs and the decrease in vector control activities to be more likely driving forces behind the malaria resurgence...
Meteorologic influences on Plasmodium falciparum malaria in the Highland Tea Estates of Kericho, Western KenyaG Dennis Shanks
U S Army Medical Research Unit Kenya, Nairobi, Africa
Emerg Infect Dis 8:1404-8. 2002..We conclude that climate changes have not caused the highland malaria resurgence in western Kenya...
Standardizing estimates of the Plasmodium falciparum parasite rateDavid L Smith
Fogarty International Center, National Institutes of Health, Building 16, 16 Center Drive, Bethesda, Maryland 20892, USA
Malar J 6:131. 2007..This confounds simple comparisons of PfPR surveys conducted at different times or places...
Heritability of malaria in AfricaMargaret J Mackinnon
School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
PLoS Med 2:e340. 2005..While many individual genes have been identified that confer protection against malaria, the overall impact of host genetics on malarial risk remains unknown...
Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsyEline L Korenromp
Malaria Control Department of WHO, Geneva, Switzerland
Lancet Infect Dis 3:349-58. 2003....
Improved diagnostic testing and malaria treatment practices in ZambiaDavidson H Hamer
Center for International Health and Development, Boston University School of Public Health, Boston, Mass 02118, USA
JAMA 297:2227-31. 2007....
Urbanization, malaria transmission and disease burden in AfricaSimon I Hay
TALA Research Group in the Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Nat Rev Microbiol 3:81-90. 2005..We find there were 1,068,505 malaria deaths in Africa in 2000 - a modest 6.7% reduction over previous iterations. The public-health implications of these findings and revised estimates are discussed...
The cost of uncomplicated childhood fevers to Kenyan households: implications for reaching international access targetsBruce A Larson
Center for International Health and Development, Boston University, 85 East Concord Street, 5th Floor, Boston, MA 02118, USA
BMC Public Health 6:314. 2006..A neglected concern is how communities will access these new medicines promptly and the costs to poor households when they are located in rural areas distant to health services...
Mapping the environmental coverage of the INDEPTH demographic surveillance system network in rural AfricaAndrew J Tatem
Department of Zoology, Spatial Ecology and Epidemiology Research Group, University of Oxford, Oxford, UK
Trop Med Int Health 11:1318-26. 2006..Here, we investigate how comprehensive is the coverage of the network of rural DSS sites in Africa in terms of the range of ecological zones found across the continent...
Improving imperfect data from health management information systems in Africa using space-time geostatisticsPeter W Gething
School of Geography, University of Southampton, Southampton, United Kingdom
PLoS Med 3:e271. 2006..Faced with this inadequacy, vital public health decisions often rely on crudely adjusted regional and national estimates of treatment burdens...
Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining controlSimon Brooker
London School of Hygiene and Tropical Medicine, Kepel Street, London, United Kingdom
Am J Trop Med Hyg 77:88-98. 2007..We suggest that both school-age children and pregnant women--groups which have the highest risk of anemia--would benefit from an integrated approach to malaria and helminth control...
Impact of malaria control on childhood anaemia in Africa -- a quantitative reviewEline L Korenromp
World Health Organization, Roll Back Malaria, Geneva, Switzerland
Trop Med Int Health 9:1050-65. 2004..To review the impact of malaria control on haemoglobin (Hb) distributions and anaemia prevalences in children under 5 in malaria-endemic Africa...
The consequences of reducing transmission of Plasmodium falciparum in AfricaRobert W Snow
Centre for Tropical Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK
Adv Parasitol 52:235-64. 2002..However, at all levels of transmission the overall balance of benefits, including reduced load on families and health services from non-life-threatening malaria, favours the widespread introduction of ITNs in endemic areas of Africa...
Scaling-up coverage with insecticide-treated nets against malaria in Africa: who should pay?Christopher Curtis
London School of Hygiene and Tropical Medicine, London, UK
Lancet Infect Dis 3:304-7. 2003..This expenditure is affordable by the world community as a whole, but not by its poorest members. Recently, funding of this order of magnitude has been committed by donor agencies for malaria control...
From chloroquine to artemether-lumefantrine: the process of drug policy change in ZambiaNaawa Sipilanyambe
Department of Community Medicine, University of Zambia, RW 0001, Lusaka, Zambia
Malar J 7:25. 2008....
Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, KenyaWendy P O'Meara
Kenya Medical Research Institute, Centre for Geographic Medicine Research Wellcome Trust Collaborative Program, Kilifi, Kenya Fogarty International Center, National Institutes of Health, Bethesda, MD, USA
Lancet 372:1555-62. 2008..We aimed to assess the epidemiological characteristics of malaria in Kilifi, Kenya, during a period of decreasing transmission intensity...
The co-distribution of Plasmodium falciparum and hookworm among African schoolchildrenSimon Brooker
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
Malar J 5:99. 2006..This is despite the potential public health importance of co-infection and synergistic opportunities for control...
WHO, the Global Fund, and medical malpractice in malaria treatmentNicholas White
Lancet 363:1160. 2004
