Research Topics
| Newton OpiyoSummaryAffiliation: Kenya Medical Research Institute Country: Kenya Publications
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Detail Information
Publications
Comparison of alternative evidence summary and presentation formats in clinical guideline development: a mixed-method studyNewton Opiyo
Health Services Research Group, KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
PLoS ONE 8:e55067. 2013..Best formats for summarising and presenting evidence for use in clinical guideline development remain less well defined. We aimed to assess the effectiveness of different evidence summary formats to address this gap...
The "Child Health Evidence Week" and GRADE grid may aid transparency in the deliberative process of guideline developmentNewton Opiyo
KEMRI Wellcome Trust Research Programme, PO Box 43640, Nairobi 00100, Kenya
J Clin Epidemiol 65:962-9. 2012..To explore the evidence translation process during a 1-week national guideline development workshop ("Child Health Evidence Week") in Kenya...
Effect of newborn resuscitation training on health worker practices in Pumwani Hospital, KenyaNewton Opiyo
Kenya Medical Research Institute KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
PLoS ONE 3:e1599. 2008..Our aim was to determine if a simple one day newborn resuscitation training (NRT) alters health worker resuscitation practices in a public hospital setting in Kenya...
What clinical signs best identify severe illness in young infants aged 0-59 days in developing countries? A systematic reviewNewton Opiyo
KEMRI Wellcome Trust Research Programme, P O Box 43640, 00100 GPO, Nairobi, Kenya
Arch Dis Child 96:1052-9. 2011..5°C or <35.5°C, change in level of activity, fast breathing/respiratory rate ≥60 breaths per minute, severe chest indrawing, grunting and cyanosis...
Young infant sepsis: aetiology, antibiotic susceptibility and clinical signsOpiyo Newton
Kenya Medical Research Institute Wellcome Trust Research Programme, 00100 GPO, Nairobi, Kenya
Trans R Soc Trop Med Hyg 101:959-66. 2007..Improved country level data on pattern of microorganisms, resistance and antibiotic use are required to help reduce mortality through development of local, evidence-based clinical guidelines...
An intervention to improve paediatric and newborn care in Kenyan district hospitals: Understanding the contextMike English
KEMRI Centre for Geographic Medicine Research Coast, and Wellcome Trust Research Programme, Box 43640, Nairobi, Kenya
Implement Sci 4:42. 2009..We have demonstrated how dynamic such contexts are, and therefore the need to consider context when interpreting an intervention's effectiveness...
Quality of hospital care for sick newborns and severely malnourished children in Kenya: a two-year descriptive study in 8 hospitalsDavid Gathara
KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
BMC Health Serv Res 11:307. 2011....
Effect of a multi-faceted quality improvement intervention on inappropriate antibiotic use in children with non-bloody diarrhoea admitted to district hospitals in KenyaCharles Opondo
Child and Newborn Health Group, KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
BMC Pediatr 11:109. 2011..This outcome was not a pre-specified end-point of the main trial...
Treatment of African children with severe malaria - towards evidence-informed clinical practice using GRADENyokabi Musila
Child and Newborn Health Group, Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
Malar J 10:201. 2011....
Experience developing national evidence-based clinical guidelines for childhood pneumonia in a low-income setting--making the GRADE?Ambrose Agweyu
Kenya Medical Research Institute Wellcome Trust Research Programme, Nairobi, Kenya
BMC Pediatr 12:1. 2012..We present our experience using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach for the recent revision of the Kenyan pediatric clinical guidelines focusing on antibiotic treatment of pneumonia...
A multifaceted intervention to implement guidelines and improve admission paediatric care in Kenyan district hospitals: a cluster randomised trialPhilip Ayieko
KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
PLoS Med 8:e1001018. 2011..However, strategies to change multiple paediatric care practices in rural hospitals have rarely been evaluated...
In-service training for health professionals to improve care of the seriously ill newborn or child in low and middle-income countries (Review)Newton Opiyo
Child and Newborn Health Group, Kenya Medical Research Institute Wellcome Trust Research Programme, PO Box 43640, Nairobi, Kenya, 00100 GPO
Cochrane Database Syst Rev 4:CD007071. 2010..To optimise appropriate policy decisions, studies should aim to collect data on resource use and costs of training implementation...
Topical umbilical cord care for prevention of infection and neonatal mortalityJamlick Karumbi
Division of Paediatrics, Ministry of Medical Services, Afya House, Nairobi, Kenya
Pediatr Infect Dis J 32:78-83. 2013..Available moderate-quality to high-quality evidence indicate that cord cleansing with 4% chlorhexidine may reduce the risk of neonatal mortality and sepsis (omphalitis) in low-resource settings...
Mini-review: Management of hypoglycaemia in children aged 0-59 monthsRobin Achoki
KEMRI Wellcome Trust Research Programme, Nairobi, Kenya
J Trop Pediatr 56:227-34. 2010..Emerging evidence suggests that sublingual sugar is a feasible and effective therapy for correction of hypoglycaemia, and should be considered where intravenous glucose is delayed or impossible...
