Diederik H R Kempen
Olthof M, Lu L, Tryfonidou M, Loozen L, Pouran B, Yaszemski M, et al
. The osteoinductive effect of controlled BMP-2 release is location-dependent. Tissue Eng Part A. 2018;: pubmed publisher
..Additionally, more bone formation in OPF-BP compared to ACS at both application sites emphasizes the role of biomaterials as a scaffold to achieve proper bone tissue formation. ..
Olthof M, Tryfonidou M, Dadsetan M, Dhert W, Yaszemski M, Kempen D, et al
. In Vitro and In Vivo Correlation of BMP-2 Release Profiles from Complex Delivery Vehicles. Tissue Eng Part C Methods. 2018;: pubmed publisher
..Altogether, these results imply that more sophisticated in vitro systems should be used in bone regeneration to accurately discriminate and predict in vivo BMP-2 release from different complex delivery vehicles. ..
Haighton M, Kempen D, Wolterbeek N, Marting L, van Dijk M, Veen R. Bridging therapy for oral anticoagulation increases the risk for bleeding-related complications in total joint arthroplasty. J Orthop Surg Res. 2015;10:145 pubmed publisher
..This risk was highest in patients with total hip arthroplasty. There were no thromboembolic events in bridged patients. ..
Olthof M, Tryfonidou M, Liu X, Pouran B, Meij B, Dhert W, et al
. Phosphate functional groups improve OPF osteoconduction and BMP-2 osteoinductive efficacy. Tissue Eng Part A. 2017;: pubmed publisher
..Therefore, functionalizing hydrogels with phosphate groups by crosslinking monomers into the hydrogel matrix could provide a valuable method for improving polymer characteristics and hold great promise for bone tissue engineering. ..