S P Keijmel
Keijmel S, van Kasteren M, Blokx W, van der Meer J, van Rossum M, Bleeker Rovers C. Cutaneous hyperpigmentation induced by doxycycline: a case series. Neth J Med. 2015;73:37-40 pubmed
..After cessation of therapy, the hyperpigmentation diminished in all four patients, illustrating the need for recognition and timely cessation of therapy. ..
Raijmakers R, Keijmel S, Breukers E, Bleijenberg G, Van der Meer J, Bleeker Rovers C, et al
. Long-term effect of cognitive behavioural therapy and doxycycline treatment for patients with Q fever fatigue syndrome: One-year follow-up of the Qure study. J Psychosom Res. 2019;116:62-67 pubmed publisher
..Due to its initial beneficial effect and side effects of long-term doxycycline use, we still recommend CBT as treatment for QFS. We suggest further investigation on tailoring CBT more to QFS, possibly followed by booster sessions. ..
Raijmakers R, Koeken V, Jansen A, Keijmel S, Roerink M, Joosten L, et al
. Cytokine profiles in patients with Q fever fatigue syndrome. J Infect. 2019;: pubmed publisher
Keijmel S, Saxe J, Van der Meer J, Nikolaus S, Netea M, Bleijenberg G, et al
. A comparison of patients with Q fever fatigue syndrome and patients with chronic fatigue syndrome with a focus on inflammatory markers and possible fatigue perpetuating cognitions and behaviour. J Psychosom Res. 2015;79:295-302 pubmed publisher
Keijmel S, Raijmakers R, Schoffelen T, Salet M, Bleeker Rovers C. A fatal case of disseminated chronic Q fever: a case report and brief review of the literature. Infection. 2016;44:677-82 pubmed publisher
..Clinicians should be aware of this silent killer, especially in case of risk factors, and perform an appropriate diagnostic work-up for Q fever including IFA serology and PCR. ..
Keijmel S, Raijmakers R, Bleeker Rovers C, Van der Meer J, Netea M, Schoffelen T, et al
. Altered interferon-Î³ response in patients with Q-fever fatigue syndrome. J Infect. 2016;72:478-85 pubmed publisher
..These results point to an altered cell-mediated immunity in QFS, and suggest a different immune response than in chronic Q-fever. ..