Gillian M Keating

Summary

Publications

  1. ncbi request reprint Rivastigmine Transdermal Patch 13.3 mg/24 h: A Review of Its Use in the Management of Mild to Moderate Alzheimer's Dementia
    James E Frampton
    Adis, Level 1, 5 The Warehouse Way, Northcote 0627 Private Bag 65901, Mairangi Bay 0754, Auckland, New Zealand
    Drugs Aging 31:639-49. 2014
  2. ncbi request reprint Pazopanib: a review of its use in the management of advanced renal cell carcinoma
    Paul L McCormack
    Adis, Level 1, 5 The Warehouse Way, Northcote 0627 Private Bag 65901, Mairangi Bay 0754, Auckland, New Zealand
    Drugs 74:1111-25. 2014
  3. ncbi request reprint Canagliflozin: a review of its use in patients with type 2 diabetes mellitus
    Greg L Plosker
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:807-24. 2014
  4. ncbi request reprint Ponatinib: a review of its use in adults with chronic myeloid leukaemia or Philadelphia chromosome-positive acute lymphoblastic leukaemia
    Sheridan M Hoy
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:793-806. 2014
  5. ncbi request reprint A Review of CT-P13: An Infliximab Biosimilar
    Kate McKeage
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    BioDrugs 28:313-21. 2014
  6. doi request reprint Elvitegravir: A Review of Its Use in Adults with HIV-1 Infection
    Emma D Deeks
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:687-97. 2014
  7. doi request reprint Degarelix: a review of its use in patients with prostate cancer
    Natalie J Carter
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:699-712. 2014
  8. ncbi request reprint Pomalidomide: a review of its use in patients with recurrent multiple myeloma
    Lesley J Scott
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:549-62. 2014
  9. ncbi request reprint Radium-223 dichloride: a review of its use in patients with castration-resistant prostate cancer with symptomatic bone metastases
    Matt Shirley
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:579-86. 2014
  10. ncbi request reprint Subcutaneous trastuzumab: a review of its use in HER2-positive breast cancer
    Mark Sanford
    Adis, Springer Healthcare, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Target Oncol 9:85-94. 2014

Collaborators

Detail Information

Publications155 found, 100 shown here

  1. ncbi request reprint Rivastigmine Transdermal Patch 13.3 mg/24 h: A Review of Its Use in the Management of Mild to Moderate Alzheimer's Dementia
    James E Frampton
    Adis, Level 1, 5 The Warehouse Way, Northcote 0627 Private Bag 65901, Mairangi Bay 0754, Auckland, New Zealand
    Drugs Aging 31:639-49. 2014
    ....
  2. ncbi request reprint Pazopanib: a review of its use in the management of advanced renal cell carcinoma
    Paul L McCormack
    Adis, Level 1, 5 The Warehouse Way, Northcote 0627 Private Bag 65901, Mairangi Bay 0754, Auckland, New Zealand
    Drugs 74:1111-25. 2014
    ..Therefore, pazopanib was noninferior to sunitinib with respect to efficacy in the treatment of advanced renal cell carcinoma, but had a differentiated tolerability profile, which affected HR-QOL and patient preference. ..
  3. ncbi request reprint Canagliflozin: a review of its use in patients with type 2 diabetes mellitus
    Greg L Plosker
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:807-24. 2014
    ....
  4. ncbi request reprint Ponatinib: a review of its use in adults with chronic myeloid leukaemia or Philadelphia chromosome-positive acute lymphoblastic leukaemia
    Sheridan M Hoy
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:793-806. 2014
    ....
  5. ncbi request reprint A Review of CT-P13: An Infliximab Biosimilar
    Kate McKeage
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    BioDrugs 28:313-21. 2014
    ..In conclusion, CT-P13 is an infliximab biosimilar that provides a useful alternative to reference infliximab in patients requiring infliximab therapy. ..
  6. doi request reprint Elvitegravir: A Review of Its Use in Adults with HIV-1 Infection
    Emma D Deeks
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:687-97. 2014
    ..Thus, single-agent elvitegravir extends the treatment options available for use in the ritonavir-boosted PI-based ART regimens of adults infected with HIV-1 and has the convenience of once-daily administration. ..
  7. doi request reprint Degarelix: a review of its use in patients with prostate cancer
    Natalie J Carter
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:699-712. 2014
    ..g. hot flushes, weight increase) were the most common treatment-emergent adverse events. Thus, degarelix is a useful option for the treatment of prostate cancer in patients for whom endocrine treatment is indicated. ..
  8. ncbi request reprint Pomalidomide: a review of its use in patients with recurrent multiple myeloma
    Lesley J Scott
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:549-62. 2014
    ..Thus, combination therapy with pomalidomide plus low-dose dexamethasone is an important emerging treatment option for use as salvage therapy in patients with relapsed and refractory multiple myeloma. ..
  9. ncbi request reprint Radium-223 dichloride: a review of its use in patients with castration-resistant prostate cancer with symptomatic bone metastases
    Matt Shirley
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:579-86. 2014
    ..Thus, radium-223 is a valuable addition to the treatment options for this poor-prognosis population. ..
  10. ncbi request reprint Subcutaneous trastuzumab: a review of its use in HER2-positive breast cancer
    Mark Sanford
    Adis, Springer Healthcare, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Target Oncol 9:85-94. 2014
    ..On the evidence, subcutaneous trastuzumab is an effective and generally well-tolerated treatment option that is preferred by patients over intravenous administration. ..
  11. doi request reprint Alemtuzumab: a review of its use in patients with relapsing multiple sclerosis
    Karly P Garnock-Jones
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:489-504. 2014
    ..More investigation is required before final conclusions can be drawn on the correct placement of alemtuzumab in multiple sclerosis treatment; however, it is of a certainty a welcome addition to the treatment options for these patients. ..
  12. doi request reprint Oxycodone/Naloxone prolonged-release: a review of its use in the management of chronic pain while counteracting opioid-induced constipation
    Celeste B Burness
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 74:353-75. 2014
    ..Although more comparative data are needed, oxycodone/naloxone PR is an effective option for use in patients with severe chronic pain, particularly among those with opioid-induced constipation. ..
  13. ncbi request reprint Aripiprazole: a review of its use in the treatment of manic episodes in adolescents with bipolar I disorder
    Kate McKeage
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    CNS Drugs 28:171-83. 2014
    ....
  14. doi request reprint Raltegravir: a review of its use in the management of HIV-1 infection in children and adolescents
    Caroline M Perry
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Paediatr Drugs 16:91-100. 2014
    ....
  15. doi request reprint Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate single-tablet regimen (Stribild®): a review of its use in the management of HIV-1 infection in adults
    Caroline M Perry
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 74:75-97. 2014
    ..It offers advantages over more complex multiple-tablet regimens that may impair treatment adherence, which is fundamental to the successful management of HIV-1 infection...
  16. ncbi request reprint Lixisenatide: a review of its use in patients with type 2 diabetes mellitus
    Lesley J Scott
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    BioDrugs 27:509-23. 2013
    ....
  17. ncbi request reprint Intrathecal ziconotide: a review of its use in patients with chronic pain refractory to other systemic or intrathecal analgesics
    Mark Sanford
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    CNS Drugs 27:989-1002. 2013
    ..At the present time, intrathecal ziconotide provides a treatment option for patients with severe, unremitting pain who have failed to respond to other intensive analgesic regimens...
  18. ncbi request reprint Pegylated liposomal doxorubicin: a guide to its use in various malignancies
    Katherine A Lyseng-Williamson
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    BioDrugs 27:533-40. 2013
    ..It has a favourable safety profile relative to conventional doxorubicin and other available chemotherapy agents. ..
  19. doi request reprint Trastuzumab: a review of its use in HER2-positive advanced gastric cancer
    Mark Sanford
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1605-15. 2013
    ....
  20. ncbi request reprint Glatiramer acetate: a review of its use in patients with relapsing-remitting multiple sclerosis and in delaying the onset of clinically definite multiple sclerosis
    Lesley J Scott
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    CNS Drugs 27:971-88. 2013
    ..Therefore, glatiramer acetate remains a valuable first-line option in the treatment of RRMS and is an option for delaying the onset of CDMS in patients with CIS...
  21. ncbi request reprint Tobramycin inhalation powder: a review of its use in the treatment of chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis
    Kate McKeage
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1815-27. 2013
    ..aeruginosa infection. Compared with nebulized TIS, TIP has a faster delivery and is more portable and convenient...
  22. doi request reprint Lacosamide: a review of its use as adjunctive therapy in the management of partial-onset seizures
    Sheridan M Hoy
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    CNS Drugs 27:1125-42. 2013
    ..Thus, oral and intravenous lacosamide as an adjunctive therapy to other AEDs provides a useful option in the treatment of patients with partial-onset seizures...
  23. doi request reprint Eculizumab: a review of its use in atypical haemolytic uraemic syndrome
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:2053-66. 2013
    ..Eculizumab is associated with an increased susceptibility to meningococcal infection, so patients should be immunized with meningococcal vaccine. In conclusion, eculizumab is a valuable new agent for use in the treatment of aHUS. ..
  24. doi request reprint Crizotinib: a review of its use in the treatment of anaplastic lymphoma kinase-positive, advanced non-small cell lung cancer
    James E Frampton
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:2031-51. 2013
    ..Key issues relating to the use of crizotinib in clinical practice include identifying the small subset of eligible patients, the almost inevitable development of resistance and the high cost of treatment. ..
  25. ncbi request reprint Enzalutamide: a review of its use in metastatic, castration-resistant prostate cancer
    Mark Sanford
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1723-32. 2013
    ..Enzalutamide carries a small increased risk of seizures that appears to be dose-dependent. Enzalutamide is an efficacious and well tolerated treatment for this severe, rapidly progressive disease...
  26. ncbi request reprint Pertuzumab: a review of its use for first-line combination treatment of HER2-positive metastatic breast cancer
    Paul L McCormack
    Adis, 41 Centorian Drive, Private Bag 65901 Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1491-502. 2013
    ..Pertuzumab had an acceptable tolerability profile when added to trastuzumab and docetaxel in the pivotal CLEOPATRA trial. Thus, pertuzumab is a valuable addition to the growing list of anti-HER2 targeted therapies for breast cancer...
  27. ncbi request reprint Eplerenone: a review of its use in patients with chronic systolic heart failure and mild symptoms
    Sohita Dhillon
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1451-62. 2013
    ....
  28. ncbi request reprint Sumatriptan iontophoretic transdermal system: a review of its use in patients with acute migraine
    Karly P Garnock-Jones
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1483-90. 2013
    ..Sumatriptan TDS is a useful addition to the treatment options available to migraine patients...
  29. pmc Quadrivalent human papillomavirus (HPV) types 6, 11, 16, 18 vaccine for the prevention of genital warts in males: profile report. demail@springer.com
    Karly P Garnock-Jones
    Adis, Auckland, New Zealand
    Drugs R D 12:235-8. 2012
    ..Adapted and reproduced from the original article published in Drugs 2011; 71 (5): 591-602.[1]...
  30. pmc Pharmacoeconomic spotlight on rotavirus vaccine RIX4414 (Rotarix™) in developed countries
    Greg L Plosker
    Adis, Auckland, New Zealand
    Drugs R D 12:239-44. 2012
    ..Actual tender prices of a full vaccination course for each vaccine were not known at the time of the analyses and therefore had to be estimated...
  31. pmc Methylphenidate transdermal system in attention-deficit hyperactivity disorder in adolescents†: profile report
    Gillian M Keating
    Adis, Auckland, New Zealand
    Drugs R D 12:171-3. 2012
    ..Adapted and reproduced from the original article published in CNS Drugs 2011; 25 (4): 333-342.[1]...
  32. doi request reprint Sumatriptan/naproxen sodium: a review of its use in adult patients with migraine
    Lily P H Yang
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:1339-55. 2013
    ..The most common adverse events were in line with those expected for sumatriptan and naproxen sodium. Current data indicate that sumatriptan/naproxen sodium is a useful option in the treatment of adult migraine. ..
  33. doi request reprint Nalmefene: a review of its use in the treatment of alcohol dependence
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    CNS Drugs 27:761-72. 2013
    ..In conclusion, as-needed nalmefene provides an important new option for use in the treatment of alcohol dependence...
  34. doi request reprint Zonisamide: a review of its use in the management of adults with partial seizures
    Sheridan M Hoy
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:1321-38. 2013
    ..Thus, oral zonisamide as monotherapy or adjunctive therapy to other AEDs provides a useful option in the treatment of patients with partial seizures. ..
  35. doi request reprint Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy
    Emma D Deeks
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Clin Drug Investig 33:689-97. 2013
    ..Ibuprofen/famotidine was generally well tolerated, with a tolerability profile consistent with those established for the individual agents...
  36. doi request reprint Recombinant trivalent influenza vaccine (flublok(®)): a review of its use in the prevention of seasonal influenza in adults
    Lily P H Yang
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:1357-66. 2013
    ..Flublok(®) is a useful and generally well-tolerated vaccination option for the prevention of seasonal influenza in adults aged 18-49 years, including those with egg allergy. ..
  37. ncbi request reprint Everolimus: a guide to its use in liver transplantation
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    BioDrugs 27:407-11. 2013
    ..Everolimus plus reduced-exposure tacrolimus has an acceptable tolerability profile in liver transplant recipients...
  38. ncbi request reprint Immune globulin (human) 10 % liquid: a review of its use in primary immunodeficiency disorders
    Paul L McCormack
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    BioDrugs 27:393-400. 2013
    ..It offers the benefits of a ready-to-use, liquid preparation and the convenience of home-based therapy in appropriate patients...
  39. ncbi request reprint Bevacizumab combination therapy: a review of its use in patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer
    Sohita Dhillon
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754 Auckland, New Zealand
    BioDrugs 27:375-92. 2013
    ..Although several unanswered questions remain, such as the optimal dosage and duration of treatment, current evidence suggests that bevacizumab combination therapy extends the treatment options available for patients with ovarian cancer...
  40. ncbi request reprint Canakinumab: a guide to its use in acute gouty arthritis flares
    Katherine A Lyseng-Williamson
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    BioDrugs 27:401-6. 2013
    ..Canakinumab has an acceptable tolerability profile in this difficult-to-treat population. The increased risk of infections and neutropenia associated with canakinumab treatment can be minimized by following the recommended precautions...
  41. ncbi request reprint Asparaginase Erwinia chrysanthemi (Erwinaze®): a guide to its use in acute lymphoblastic leukemia in the USA
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    BioDrugs 27:413-8. 2013
    ..Subclinical hypersensitivity may result in the inactivation of asparaginase and affect treatment outcome; monitoring of serum asparaginase levels may be used to identify subclinical hypersensitivity...
  42. doi request reprint Mirabegron: a review of its use in patients with overactive bladder syndrome
    Mark Sanford
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1213-25. 2013
    ..Mirabegron 50 mg once daily carries a low risk of QT interval prolongation. Thus, mirabegron is an efficacious new treatment for overactive bladder syndrome with a favourable tolerability profile...
  43. doi request reprint Shingles (herpes zoster) vaccine (zostavax(®)): a review of its use in the prevention of herpes zoster and postherpetic neuralgia in adults aged ≥50 years
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1227-44. 2013
    ..In conclusion, zoster vaccine provides an important opportunity to reduce the burden of illness associated with herpes zoster by reducing the incidence of herpes zoster and postherpetic neuralgia...
  44. doi request reprint Omalizumab: a review of its use in patients with severe persistent allergic asthma
    Kate McKeage
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:1197-212. 2013
    ..Thus, in difficult-to-treat patients with severe persistent allergic asthma, omalizumab provides a valuable treatment option...
  45. doi request reprint Crofelemer: a review of its use in the management of non-infectious diarrhoea in adult patients with HIV/AIDS on antiretroviral therapy
    James E Frampton
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:1121-9. 2013
    ..Treatment with crofelemer had no appreciable effect on immune parameters, such as HIV viral load and CD4+ cell counts...
  46. doi request reprint Ceftaroline fosamil: a review of its use in the treatment of complicated skin and soft tissue infections and community-acquired pneumonia
    James E Frampton
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:1067-94. 2013
    ..As with all antibacterial agents, ceftaroline fosamil should be used in accordance with good antimicrobial stewardship...
  47. doi request reprint Abatacept: a review of its use in the management of rheumatoid arthritis
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:1095-119. 2013
    ..Abatacept was generally well tolerated in RA and JIA and was associated with low rates of immunogenicity. In conclusion, abatacept is an important option for use in the treatment of RA and JIA...
  48. doi request reprint Adalimumab: a review of its use in the treatment of patients with ulcerative colitis
    Celeste B Burness
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    BioDrugs 27:247-62. 2013
    ..Adalimumab provides a new treatment option for patients with moderately to severely active ulcerative colitis who are refractory to, or intolerant of, corticosteroids and/or immunomodulators...
  49. doi request reprint Multicomponent meningococcal serogroup B vaccine (4CMenB; Bexsero(®)): a review of its use in primary and booster vaccination
    Natalie J Carter
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    BioDrugs 27:263-74. 2013
    ..In conclusion, 4CMenB effectively elicited immune responses against meningococcal serogroup B test strains selected to be specific for the vaccine antigens in infants, adolescents, and adults...
  50. doi request reprint Dasatinib: a guide to its use in chronic myeloid leukemia in the EU
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    BioDrugs 27:275-9. 2013
    ..Thus, dasatinib is a highly effective, once-daily therapy for the first-line treatment of patients with chronic-phase CML and for the second-line treatment of imatinib-resistant or imatinib-intolerant CML...
  51. doi request reprint Landiolol: a review of its use in intraoperative and postoperative tachyarrhythmias
    Greg L Plosker
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 73:959-77. 2013
    ....
  52. doi request reprint Decitabine: a review of its use in older patients with acute myeloid leukaemia
    Monique P Curran
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs Aging 30:447-58. 2013
    ..In conclusion, low-dose decitabine may be considered as an effective and generally well tolerated alternative treatment to cytarabine or supportive care in older patients with AML who are not candidates for standard induction therapy...
  53. doi request reprint Loxapine inhalation powder: a review of its use in the acute treatment of agitation in patients with bipolar disorder or schizophrenia
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    CNS Drugs 27:479-89. 2013
    ..In conclusion, inhaled loxapine provides a novel new option for use in the acute treatment of agitation in patients with bipolar disorder or schizophrenia, combining a rapid onset of effect with a noninvasive route of administration...
  54. doi request reprint Apixaban: a review of its use for reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 73:825-43. 2013
    ..In conclusion, although longer-term efficacy and safety data are needed, apixaban is an important new option for use in patients with nonvalvular AF to reduce the risk of stroke or systemic embolism...
  55. doi request reprint Loteprednol etabonate ophthalmic gel 0.5%: a review of its use in post-operative inflammation and pain following ocular surgery
    Katherine A Lyseng-Williamson
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 73:949-58. 2013
    ..It provides uniform dosing of a topical ophthalmic corticosteroid that has been demonstrated to be effective and well-tolerated in the treatment of ocular inflammation...
  56. ncbi request reprint Meningococcal groups C and Y and haemophilus B tetanus toxoid conjugate vaccine (HibMenCY-TT; MenHibrix(®)): a review
    Caroline M Perry
    Adis, 41 Centorian Drive Private Bag 65901 Mairangi Bay North Shore, 0754 Auckland, New Zealand
    Drugs 73:703-13. 2013
    ..The tolerability profile of the HibMenCY-TT vaccine in infants and toddlers in the phase III trial was considered to be clinically acceptable and comparable to that of the Hib conjugate vaccines received by the control group...
  57. ncbi request reprint Rivaroxaban: a review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation
    Natalie J Carter
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Drugs 73:715-39. 2013
    ..Thus, rivaroxaban is a reasonable alternative to warfarin for the prevention of stroke and systemic embolism in patients with NVAF...
  58. ncbi request reprint Inhaled glycopyrronium bromide: a review of its use in patients with moderate to severe chronic obstructive pulmonary disease
    Natalie J Carter
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:741-53. 2013
    ..In conclusion, inhaled glycopyrronium bromide is a once-daily LAMA that is an effective bronchodilator for use in the treatment of patients with moderate to severe COPD...
  59. doi request reprint S-1 (Teysuno®): a review of its use in advanced gastric cancer in non-Asian populations
    M Sanford
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, Auckland 0754, New Zealand
    Drugs 73:845-55. 2013
    ..S-1 is a useful alternative to 5-FU for patients with advanced gastric cancer...
  60. doi request reprint Tofacitinib: a review of its use in adult patients with rheumatoid arthritis
    Lesley J Scott
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 73:857-74. 2013
    ....
  61. doi request reprint Insulin degludec and insulin degludec/insulin aspart: a review of their use in the management of diabetes mellitus
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 73:575-93. 2013
    ..Subcutaneous insulin degludec was generally well tolerated in patients with type 1 or 2 diabetes. In conclusion, insulin degludec and insulin degludec/insulin aspart represent a useful advance in the treatment of type 1 or 2 diabetes...
  62. doi request reprint Pasireotide: a review of its use in Cushing's disease
    Kate McKeage
    Adis, 41 Centorian Drive Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 73:563-74. 2013
    ..Thus, pasireotide, together with on-going patient monitoring, provides a promising new option for the medical management of Cushing's disease...
  63. doi request reprint Ivabradine: in adults with chronic heart failure with reduced left ventricular ejection fraction
    Caroline M Perry
    Adis, Auckland, New Zealand
    Am J Cardiovasc Drugs 12:415-26. 2012
    ..Cardiovascular adverse events, including bradycardia, were the most common adverse events reported with ivabradine...
  64. doi request reprint Irbesartan/amlodipine: a review of its use in adult patients with essential hypertension not adequately controlled with monotherapy
    Karly P Garnock-Jones
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand
    Am J Cardiovasc Drugs 13:141-50. 2013
    ..The most frequent adverse event was peripheral oedema, generally associated with amlodipine treatment...
  65. doi request reprint Ranibizumab: a review of its use in the treatment of neovascular age-related macular degeneration
    James E Frampton
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs Aging 30:331-58. 2013
    ....
  66. doi request reprint Cabazitaxel: a guide to its use in hormone-refractory metastatic prostate cancer
    Gillian M Keating
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs Aging 30:359-65. 2013
    ..Intravenous cabazitaxel had an acceptable tolerability profile, with haematological adverse events occurring most commonly, and diarrhoea being the most common nonhaematological adverse event...
  67. doi request reprint Lorcaserin: a review of its use in chronic weight management
    Sheridan M Hoy
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 73:463-73. 2013
    ..From these and other data, the FDA has concluded that lorcaserin is unlikely to elevate the risk of valvulopathy...
  68. doi request reprint Everolimus in combination with exemestane: a review of its use in the treatment of patients with postmenopausal hormone receptor-positive, HER2-negative advanced breast cancer
    Sohita Dhillon
    Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754 Auckland, New Zealand
    Drugs 73:475-85. 2013
    ....
  69. doi request reprint A/H5N1 prepandemic influenza vaccine (Vepacel®): a guide to its use
    Gillian M Keating
    Adis, Auckland, New Zealand
    BioDrugs 26:425-30. 2012
    ..In general, adverse events observed in clinical immunogenicity studies with a whole virions H5N1 vaccine (A/Vietnam/1203/2004) were similar to those reported with non-adjuvanted, inactivated, split virion seasonal influenza vaccines...
  70. doi request reprint Belatacept: in adult kidney transplant recipients
    Karly P Garnock-Jones
    Adis, Auckland, New Zealand
    BioDrugs 26:413-24. 2012
    ....
  71. doi request reprint Vandetanib: a guide to its use in advanced medullary thyroid cancer
    Gillian M Keating
    Adis, Auckland, New Zealand
    BioDrugs 26:431-5. 2012
    ..It has an acceptable tolerability profile in this patient population, although it does have the potential to prolong the corrected QT interval...
  72. doi request reprint Micafungin: a review of its use in the prophylaxis and treatment of invasive Candida infections
    Lesley J Scott
    Adis, Auckland, New Zealand
    Drugs 72:2141-65. 2012
    ....
  73. doi request reprint Ruxolitinib: in the treatment of myelofibrosis
    Lily P H Yang
    Adis, Auckland, New Zealand
    Drugs 72:2117-27. 2012
    ..These haematological adverse events were mainly managed with dosage interruptions/reductions and/or transfusions, and rarely resulted in discontinuation...
  74. doi request reprint Pazopanib: in advanced soft tissue sarcoma
    Emma D Deeks
    Adis, Auckland, New Zealand
    Drugs 72:2129-40. 2012
    ..Oral pazopanib generally had no detrimental effect on health-related quality of life and had an acceptable tolerability profile in patients with STS in the PALETTE trial, with adverse events generally being grade 1 or 2 in severity...
  75. doi request reprint Axitinib: in advanced, treatment-experienced renal cell carcinoma
    Lily P H Yang
    Adis, Auckland, New Zealand
    Drugs 72:2375-84. 2012
    ....
  76. doi request reprint Adalimumab: in non-radiographic axial spondyloarthritis
    Celeste B Burness
    Adis, Auckland, New Zealand
    Drugs 72:2385-95. 2012
    ..Adalimumab was generally well tolerated in clinical trials of non-radiographic axSpA; the adverse event profile was similar to that in patients with AS or other approved indications...
  77. doi request reprint Ingenol mebutate gel 0.015% and 0.05%: in actinic keratosis
    Gillian M Keating
    Adis, Auckland, New Zealand
    Drugs 72:2397-405. 2012
    ..Application-site conditions were the most commonly occurring adverse events...
  78. doi request reprint Meningococcal quadrivalent (serogroups A, C, W135 and Y) tetanus toxoid conjugate vaccine (Nimenrix™)
    Jamie D Croxtall
    Adis, Auckland, New Zealand
    Drugs 72:2407-30. 2012
    ....
  79. doi request reprint Boceprevir: a review of its use in the management of chronic hepatitis C genotype 1 infection
    Karly P Garnock-Jones
    Adis, Auckland, New Zealand
    Drugs 72:2431-56. 2012
    ..Thus, boceprevir in combination with peginterferon-alpha and ribavirin is a valuable new treatment option for use in patients with chronic hepatitis C genotype 1 infection...
  80. doi request reprint Insulin detemir: a review of its use in the management of diabetes mellitus
    Gillian M Keating
    Adis, Auckland, New Zealand
    Drugs 72:2255-87. 2012
    ..In conclusion, insulin detemir is a useful option for use as basal insulin therapy in patients with type 1 or 2 diabetes...
  81. ncbi request reprint Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma
    Sheridan M Hoy
    Adis, Auckland, New Zealand
    Drugs 72:1929-50. 2012
    ....
  82. ncbi request reprint Nomegestrol acetate/estradiol: in oral contraception
    Lily P H Yang
    Adis, Auckland, New Zealand
    Drugs 72:1917-28. 2012
    ..Overall, compared with drospirenone/ethinylestradiol, nomegestrol acetate/estradiol appeared to be associated with less favourable acne-related outcomes, and shorter, lighter or absent periods...
  83. ncbi request reprint Oromucosal midazolam: a guide to its use in paediatric patients with prolonged acute convulsive seizures
    Lesley J Scott
    Adis, Auckland, New Zealand
    CNS Drugs 26:893-7. 2012
    ..It has several advantages over rectal diazepam, the previous gold standard of treatment, such as having a more convenient and socially acceptable administration route...
  84. ncbi request reprint Alteplase: a review of its use in the management of acute ischaemic stroke
    Sohita Dhillon
    Adis, Auckland, New Zealand
    CNS Drugs 26:899-926. 2012
    ..Further randomized trials of alteplase administered >4.5 hours after stroke in selected patients are required to confirm these findings...
  85. doi request reprint Ferumoxytol: in iron deficiency anaemia in adults with chronic kidney disease
    Paul L McCormack
    Adis, Auckland, New Zealand
    Drugs 72:2013-22. 2012
    ..Local injection-site reactions were the most common system/organ-class adverse events in a pooled analysis of clinical studies and post-marketing experience...
  86. doi request reprint Carfilzomib: in relapsed, or relapsed and refractory, multiple myeloma
    Paul L McCormack
    Adis, Auckland, New Zealand
    Drugs 72:2023-32. 2012
    ..6 months. Carfilzomib had an acceptable tolerability profile in patients with relapsed, or relapsed and refractory, multiple myeloma. There was a low incidence of grade 3 or higher peripheral neuropathy...
  87. ncbi request reprint Agalsidase alfa: a review of its use in the management of Fabry disease
    Gillian M Keating
    BioDrugs 26:335-54. 2012
    ..No antibody formation was reported in women receiving agalsidase alfa in noncomparative studies. In conclusion, agalsidase alfa is an effective and well tolerated treatment option for use in patients with Fabry disease...
  88. ncbi request reprint Vemurafenib: in unresectable or metastatic melanoma
    Gillian M Keating
    BioDrugs 26:325-34. 2012
    ..Cutaneous squamous cell carcinoma and/or keratoacanthoma were reported in 18% of vemurafenib recipients in the BRIM-3 trial...
  89. ncbi request reprint Recombinant human c1 inhibitor (conestat alfa): in the treatment of angioedema attacks in hereditary angioedema
    Greg L Plosker
    BioDrugs 26:315-23. 2012
    ..In the two randomized controlled trials, headache and vertigo were the only adverse events deemed to be related to study treatment...
  90. ncbi request reprint Linagliptin: a review of its use in the management of type 2 diabetes mellitus
    Emma D Deeks
    Adis, Auckland, New Zealand
    Drugs 72:1793-824. 2012
    ....
  91. ncbi request reprint Reduced-antigen, combined diphtheria, tetanus and acellular pertussis vaccine, adsorbed (Boostrix®): a review of its properties and use as a single-dose booster immunization
    Paul L McCormack
    Adis, Auckland, New Zealand
    Drugs 72:1765-91. 2012
    ....
  92. doi request reprint Frovatriptan: a review of its use in the acute treatment of migraine
    Mark Sanford
    Adis, Auckland, New Zealand
    CNS Drugs 26:791-811. 2012
    ....
  93. doi request reprint Rasagiline: a guide to its use in Parkinson's disease
    Gillian M Keating
    Adis, Auckland, New Zealand
    CNS Drugs 26:781-5. 2012
    ..5 or 1 mg/day significantly reduces the total daily 'off' time. Rasagiline is generally well tolerated when administered as monotherapy or as adjunctive therapy...
  94. doi request reprint Transdermal granisetron: a guide to its use in preventing nausea and vomiting induced by chemotherapy
    Gillian M Keating
    Adis, Auckland, New Zealand
    CNS Drugs 26:787-90. 2012
    ..Thus, transdermal granisetron provides a convenient option for the prevention of chemotherapy-induced nausea and vomiting, with the potential to improve patient compliance...
  95. doi request reprint DTPa-HBV-IPV/Hib vaccine (Infanrix hexa™): a guide to its use in infants
    Katherine A Lyseng-Williamson
    Adis, Auckland, New Zealand
    Paediatr Drugs 14:337-43. 2012
    ....
  96. doi request reprint Etravirine: a guide to its use in treatment-experienced pediatric patients with HIV-1 infection in the US
    Katherine A Lyseng-Williamson
    Adis, Auckland, New Zealand
    Paediatr Drugs 14:345-50. 2012
    ....
  97. doi request reprint Azilsartan medoxomil: a review of its use in hypertension
    Caroline M Perry
    Adis, Auckland, New Zealand
    Clin Drug Investig 32:621-39. 2012
    ..Further studies are required to evaluate the effects of azilsartan medoxomil on cardiovascular morbidity and mortality...
  98. doi request reprint Intravenous busulfan: a guide to its use as conditioning treatment before transplantation of haematopoietic progenitor cells
    Lesley J Scott
    Adis, Auckland, New Zealand
    Clin Drug Investig 32:641-8. 2012
    ..Intravenous busulfan was considered to have an acceptable tolerability profile...
  99. doi request reprint Dabigatran etexilate: a pharmacoeconomic review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation
    Kate McKeage
    Pharmacoeconomics 30:841-55. 2012
    ..However, the incremental cost per QALY gained for dabigatran versus warfarin improved when levels of international normalized ratio control in warfarin recipients decreased and when the baseline level of risk of stroke increased...
  100. doi request reprint Ipilimumab: a guide to its use in advanced melanoma
    Katherine A Lyseng-Williamson
    Adis, Auckland, New Zealand
    Am J Clin Dermatol 13:349-54. 2012
    ..Novel immune-related events that are not typical of other anticancer agents, most commonly dermatologic and gastrointestinal disorders, can occur with ipilimumab, necessitating specific monitoring and management protocols...
  101. doi request reprint Vismodegib: in locally advanced or metastatic basal cell carcinoma
    Gillian M Keating
    Adis, Auckland, New Zealand
    Drugs 72:1535-41. 2012
    ..6 months and median progression-free survival was 9.5 months. Oral vismodegib had an acceptable tolerability profile in patients with advanced BCC...