Roles of caudal-related homeobox gene Cdx1 in oesophageal epithelial cells in Barrett's epithelium developmentH Kazumori
Department of Internal Medicine, Izumo City General Medical Center, 613 Nadabun cho, Izumo, Shimane 691 0003, Japan
Gut 58:620-8. 2009
..Furthermore, we investigated the relationship between Cdx1 and Cdx2 expression in cultured oesophageal squamous epithelial cells...
Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonistsH Sato
Second Department of Internal Medicine, Shimane Medical University, Izumo, Shimane, Japan
Br J Cancer 83:1394-400. 2000
..These results suggest that induction of apoptosis together with G1 cell cycle arrest may be one of the mechanisms of the antiproliferative effect of PPARgamma activation in human gastric cancer cells...
Intragastric distribution of Helicobacter pylori during short-term omeprazole therapy: study using Carnoy's fixation and immunohistochemistry for detection of bacteriaS Ishihara
Department of Internal Medicine II, Shimane Medical University, Izumo, Shimane, Japan
Aliment Pharmacol Ther 15:1485-91. 2001
..There is controversy about the effect of acid-suppressive therapy on Helicobacter pylori density and the severity of histological gastritis in the corpus...
- Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium
H Kazumori
Department of Gastroenterology and Hepatology, Shimane University, School of Medicine, 89 1 Enya cho, Izumo, Shimane 693 8501, Japan
Gut 55:16-25. 2006
..In addition, morphological and histochemical changes in squamous cells to intestinal epithelial cells were studied in response to bile acid induced expression of Cdx2...
- T cell-mediated cytotoxicity via Fas/Fas ligand signaling in Helicobacter pylori-infected gastric corpus
S Ishihara
Department of Internal Medicine II, Shimane Medical University, Izumo, Shimane, Japan
Helicobacter 6:283-93. 2001
..The aim of this study was to investigate the involvement of the Fas/Fas ligand (Fas/Fas-L) system in the H. pylori-infected gastric corpus...
- Peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition of human hepatocellular carcinoma
M A Rumi
Second Department of Internal Medicine, Shimane Medical University, Izumo, Japan
Br J Cancer 84:1640-7. 2001
..The growth inhibitory effect was associated with a dose-dependent inhibition of DNA synthesis, cell cycle progression and alpha fetoprotein expression...
- Influence of Helicobacter pylori infection and cetraxate on gastric mucosal blood flow during healing of endoscopic mucosal resection-induced ulcers
K Adachi
Department of Internal Medicine II, Shimane Medical University, Izumo, Shimane, Japan
J Gastroenterol Hepatol 16:1211-6. 2001
..The aim of this study is to clarify the effect of H. pylori infection and cetraxate on MBF during gastric ulcer healing...
- Reg I-knockout mice reveal its role in regulation of cell growth that is required in generation and maintenance of the villous structure of small intestine
T Ose
Department of Gastroenterology and Hepatology, School of Medicine Formerly Second Department of Internal Medicine and Anatomy, Shimane Medical University, Shimane University, Izumo, Japan
Oncogene 26:349-59. 2007
..Reg I was considered to be a regulator of cell growth that is required to generate and maintain the villous structure of the small intestine...
- Can PPAR gamma ligands be used in cancer therapy?
M A K Rumi
Department of Gastroenterology and Hepatology, Shimane University School of Medicine, Izumo, Shimane 693 0021, Japan
Curr Med Chem Anticancer Agents 4:465-77. 2004
..In this review, we have addressed these controversies on potential use of PPARgamma ligands in cancer therapy...
- Time-course changes of ECL cell markers in acetic acid-induced gastric ulcers in rats
H Kazumori
Second Department of Internal Medicine, Shimane Medical University, Izumo, Japan
Aliment Pharmacol Ther 16:10-9. 2002
..As a result, we concluded that a suppression of ECL cell activity during ulcer healing may be involved in suppressed gastric acid secretion...
- Activation of prostaglandin E2-receptor EP2 and EP4 pathways induces growth inhibition in human gastric carcinoma cell lines
T Okuyama
Second Department of Internal Medicine, Shimane Medical University, Izumo, Shimane, Japan
J Lab Clin Med 140:92-102. 2002
..In summary, gastric cancer cells have EP2 and EP4 receptors, and their selective activation is linked with the decreased cell proliferation...
- Sclerosing cholangitis and systemic lymphadenopathy
H Kazumori
Second Department of Internal Medicine, Shimane Medical University, Izumo, Japan
J Gastroenterol 36:429-32. 2001
..This case suggests that there is an association between sclerosing cholangitis and immunologic abnormalities, and that corticosteroid treatment is useful for this disorder...
