Walter H Kaye

Summary

Publications

  1. doi request reprint Neurocircuity of eating disorders
    Walter H Kaye
    Department of Psychiatry, University of California, San Diego, CA, USA
    Curr Top Behav Neurosci 6:37-57. 2011
  2. pmc Sexual functioning in women with eating disorders
    Andrea Poyastro Pinheiro
    Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, USA
    Int J Eat Disord 43:123-9. 2010
  3. pmc Posttraumatic stress disorder in anorexia nervosa
    Mae Lynn Reyes-Rodríguez
    Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
    Psychosom Med 73:491-7. 2011
  4. pmc Substance use disorders in women with anorexia nervosa
    Tammy L Root
    Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
    Int J Eat Disord 43:14-21. 2010
  5. doi request reprint Suicide attempts in anorexia nervosa
    Cynthia M Bulik
    Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
    Psychosom Med 70:378-83. 2008
  6. doi request reprint Influence of overanxious disorder of childhood on the expression of anorexia nervosa
    T J Raney
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 41:326-32. 2008
  7. pmc Factors associated with recovery from anorexia nervosa
    Stephanie Zerwas
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7160, USA
    J Psychiatr Res 47:972-9. 2013
  8. ncbi request reprint Altered insula response to taste stimuli in individuals recovered from restricting-type anorexia nervosa
    Angela Wagner
    Department of Psychiatry, School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neuropsychopharmacology 33:513-23. 2008
  9. pmc Childhood anxiety associated with low BMI in women with anorexia nervosa
    Jocilyn E Dellava
    Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
    Behav Res Ther 48:60-7. 2010
  10. pmc Understanding the association of impulsivity, obsessions, and compulsions with binge eating and purging behaviours in anorexia nervosa
    Elizabeth R Hoffman
    Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
    Eur Eat Disord Rev 20:e129-36. 2012

Collaborators

Detail Information

Publications37

  1. doi request reprint Neurocircuity of eating disorders
    Walter H Kaye
    Department of Psychiatry, University of California, San Diego, CA, USA
    Curr Top Behav Neurosci 6:37-57. 2011
    ..This chapter reviews brain imaging findings in anorexia and bulimia nervosa which characterize brain circuitry that may contribute to the pathophysiology of eating disorders (EDs)...
  2. pmc Sexual functioning in women with eating disorders
    Andrea Poyastro Pinheiro
    Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, USA
    Int J Eat Disord 43:123-9. 2010
    ..To describe sexual functioning in women with eating disorders...
  3. pmc Posttraumatic stress disorder in anorexia nervosa
    Mae Lynn Reyes-Rodríguez
    Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
    Psychosom Med 73:491-7. 2011
    ..The main objectives of this study were to describe the nature of traumatic events experienced and to explore the relationship between PTSD and anorexia nervosa (AN) in a sample of women...
  4. pmc Substance use disorders in women with anorexia nervosa
    Tammy L Root
    Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
    Int J Eat Disord 43:14-21. 2010
    ..Secondary analyses examined SUD related to lifetime purging behavior and lifetime binge eating...
  5. doi request reprint Suicide attempts in anorexia nervosa
    Cynthia M Bulik
    Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
    Psychosom Med 70:378-83. 2008
    ..To explore prevalence and patterns of suicidal attempts in persons with anorexia nervosa (AN)...
  6. doi request reprint Influence of overanxious disorder of childhood on the expression of anorexia nervosa
    T J Raney
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 41:326-32. 2008
    ..This study investigates the prevalence of overanxious disorder (OAD) among women with AN and explores how OAD impacts AN symptoms and personality traits...
  7. pmc Factors associated with recovery from anorexia nervosa
    Stephanie Zerwas
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7160, USA
    J Psychiatr Res 47:972-9. 2013
    ..The anxiolytic function of some AN behaviors may impede recovery for individuals with greater trait anxiety...
  8. ncbi request reprint Altered insula response to taste stimuli in individuals recovered from restricting-type anorexia nervosa
    Angela Wagner
    Department of Psychiatry, School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Neuropsychopharmacology 33:513-23. 2008
    ..These data provide the first evidence that individuals with AN process taste stimuli differently than controls, based on differences in neural activation patterns...
  9. pmc Childhood anxiety associated with low BMI in women with anorexia nervosa
    Jocilyn E Dellava
    Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
    Behav Res Ther 48:60-7. 2010
    ..The present study explores childhood personality characteristics that could be associated with the ability to attain an extremely low BMI...
  10. pmc Understanding the association of impulsivity, obsessions, and compulsions with binge eating and purging behaviours in anorexia nervosa
    Elizabeth R Hoffman
    Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
    Eur Eat Disord Rev 20:e129-36. 2012
    ..To further refine our understanding of impulsivity, obsessions, and compulsions in anorexia nervosa (AN) by isolating which behaviours--binge eating, purging, or both--are associated with these features...
  11. doi request reprint Altered striatal response to reward in bulimia nervosa after recovery
    Angela Wagner
    Department of Psychiatry, School of Medicine, University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
    Int J Eat Disord 43:289-94. 2010
    ..It is possible that disturbances of systems modulating reward may contribute to a vulnerability to develop an eating disorder...
  12. pmc Association study of 182 candidate genes in anorexia nervosa
    Andrea Poyastro Pinheiro
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
    Am J Med Genet B Neuropsychiatr Genet 153:1070-80. 2010
    ....
  13. pmc Life beyond the eating disorder: education, relationships, and reproduction
    Millie Maxwell
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 44:225-32. 2011
    ..We investigated the sociodemographic characteristics in women with and without lifetime eating disorders...
  14. doi request reprint Temporal patterns of recovery across eating disorder subtypes
    Ann Von Holle
    Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
    Aust N Z J Psychiatry 42:108-17. 2008
    ..To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN)...
  15. ncbi request reprint Regional cerebral blood flow after recovery from anorexia or bulimia nervosa
    Guido K Frank
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Int J Eat Disord 40:488-92. 2007
    ..Abnormalities of regional cerebral blood flow (rCBF) have been found in individuals who are ill with anorexia (AN) or bulimia nervosa (BN). Little is known about whether rCBF normalizes after recovery from AN and BN...
  16. doi request reprint Primary amenorrhea in anorexia nervosa: impact on characteristic masculine and feminine traits
    Jessica H Baker
    Department of Psychiatry, University of North Carolina, USA
    Eur Eat Disord Rev 22:32-8. 2014
    ..Copyright © 2013 John Wiley & Sons, Ltd and Eating Disorders Association. ..
  17. pmc Does a shared neurobiology for foods and drugs of abuse contribute to extremes of food ingestion in anorexia and bulimia nervosa?
    Walter H Kaye
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Biol Psychiatry 73:836-42. 2013
    ....
  18. pmc Altered insula activation during pain anticipation in individuals recovered from anorexia nervosa: evidence of interoceptive dysregulation
    Irina A Strigo
    Department of Psychiatry, University of California San Diego, 3350 La Jolla Village Dr, Building 13, MC 9151 B, La Jolla, CA 92161, USA
    Int J Eat Disord 46:23-33. 2013
    ..Pain is an interoceptive process with well-characterized neuroanatomical pathways that may overlap to a large degree with neural systems that may be dysregulated in individuals with AN, such as the insula...
  19. pmc An examination of early childhood perfectionism across anorexia nervosa subtypes
    Katherine A Halmi
    Department of Psychiatry, Weill Cornell Medical College, NY, USA
    Int J Eat Disord 45:800-7. 2012
    ..To examine childhood perfectionism in anorexia nervosa (AN) restricting (RAN), purging (PAN), and binge eating with or without purging (BAN) subtypes...
  20. doi request reprint New insights into symptoms and neurocircuit function of anorexia nervosa
    Walter H Kaye
    Eating Disorder Treatment and Research Program, Department of Psychiatry, University of California, San Diego, La Jolla Village Professional Center, 8950 Villa La Jolla Drive, Suite C 207, La Jolla, California 92037, USA
    Nat Rev Neurosci 10:573-84. 2009
    ..For example, altered insula activity could explain interoceptive dysfunction, and altered striatal activity might shed light on altered reward modulation in people with anorexia nervosa...
  21. ncbi request reprint Patterns of menstrual disturbance in eating disorders
    Andréa Poyastro Pinheiro
    Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 40:424-34. 2007
    ..To describe menstrual disturbance in eating disorders (ED)...
  22. ncbi request reprint Exaggerated 5-HT1A but normal 5-HT2A receptor activity in individuals ill with anorexia nervosa
    Ursula F Bailer
    Department of Psychiatry, Western Psychiatric Institute and Clinic, School of Medicine, Pittsburgh, University of Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 61:1090-9. 2007
    ..Because little is known about 5-HT receptor function in AN, positron emission tomography (PET) imaging with 5-HT receptor-specific radioligands was used to characterize 5-HT1A and 5-HT2A receptors...
  23. pmc Altered brain response to reward and punishment in adolescents with Anorexia nervosa
    Amanda Bischoff-Grethe
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Psychiatry Res 214:331-40. 2013
    ..As AN individuals are particularly sensitive to criticism, failure, and making mistakes, these findings may reflect the neural processes responsible for a bias in those with AN to exaggerate negative consequences. ..
  24. ncbi request reprint 5HT2A receptor binding is increased in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Biol Psychiatry 62:580-7. 2007
    ..We examined 5HT(2A) receptor binding potential (BP) in impulsive subjects with BPD, with positron emission tomography neuroimaging with [(18)F] altanserin...
  25. pmc Nothing tastes as good as skinny feels: the neurobiology of anorexia nervosa
    Walter H Kaye
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Trends Neurosci 36:110-20. 2013
    ..An understanding of the neurobiology of this disorder is likely to be important for developing more effective treatments...
  26. pmc Differential weight restoration on olanzapine versus fluoxetine in identical twins with anorexia nervosa
    Vikas Duvvuri
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92037, USA
    Int J Eat Disord 45:294-7. 2012
    ..No studies have compared the response to selective serotonin reuptake inhibitors and atypical antipsychotics in anorexia nervosa. This case study examines such a comparison...
  27. ncbi request reprint Sucrose activates human taste pathways differently from artificial sweetener
    Guido K W Frank
    University of Colorado at Denver and Health Sciences Center, Department of Psychiatry, The Children s Hospital, Aurora, CO 80045, USA
    Neuroimage 39:1559-69. 2008
    ..This could have important implications on how effective artificial sweeteners are in their ability to substitute sugar intake...
  28. pmc Cognitive set-shifting in anorexia nervosa
    Megan E Shott
    Department of Psychiatry, University of Colorado Denver, CO, USA
    Eur Eat Disord Rev 20:343-9. 2012
    ..Adult anorexia nervosa (AN) is associated with inefficient cognitive flexibility and set-shifting. Whether such inefficiencies also characterize adolescent AN is an important area of research...
  29. pmc Postpartum and depression status are associated with lower [[¹¹C]raclopride BP(ND) in reproductive-age women
    Eydie L Moses-Kolko
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Neuropsychopharmacology 37:1422-32. 2012
    ....
  30. doi request reprint Demand-specific alteration of medial prefrontal cortex response during an inhibition task in recovered anorexic women
    Tyson A Oberndorfer
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92037, USA
    Int J Eat Disord 44:1-8. 2011
    ..It is well known that individuals with anorexia nervosa (AN) are inhibited and over-controlled. This study investigated a prefrontal-cingulate network that is involved in inhibitory control...
  31. pmc Alterations in white matter microstructure in women recovered from anorexia nervosa
    Wai Ying Wendy Yau
    Department of Psychiatry, University of California, San Diego, La Jolla, California
    Int J Eat Disord 46:701-8. 2013
    ..This study was designed to determine whether such alterations exist in long-term recovered AN individuals and to examine potential associations with underlying AN traits...
  32. pmc Interoceptive sensitivity deficits in women recovered from bulimia nervosa
    Megan Klabunde
    Department of Psychiatry, Stanford University, Stanford, CA, United States Electronic address
    Eat Behav 14:488-92. 2013
    ..These results suggest that deficits in interoceptive sensitivity are present in individuals recovered from BN. Thus interoceptive deficits may be one factor that bridges the gap between brain dysfunction and symptom presentation in BN...
  33. doi request reprint Aripiprazole in anorexia nervosa and low-weight bulimia nervosa: case reports
    Mary Ellen Trunko
    Department of Psychiatry, University of California San Diego, San Diego, California, USA
    Int J Eat Disord 44:269-75. 2011
    ..However, newer, more weight-neutral medications have not been studied in AN, and there are no reports of the use of antipsychotics in bulimia nervosa (BN)...
  34. doi request reprint An innovative short-term, intensive, family-based treatment for adolescent anorexia nervosa: case series
    Roxanne E Rockwell
    University of California, San Diego, Department of Psychiatry, La Jolla, CA, USA
    Eur Eat Disord Rev 19:362-7. 2011
    ..Ages of the adolescents in the programme ranged from 10 to 18 years (mean = 15.0, SD = 2.1). We report the outcomes of the first 19 cases...
  35. ncbi request reprint Smoking in eating disorders
    Doris Anzengruber
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7160, USA
    Eat Behav 7:291-9. 2006
    ..The aim of this paper was to explore the patterns and prevalence of smoking behavior in 1,524 women from two of the multisite Price Foundation Genetic studies...
  36. ncbi request reprint Neural correlates of habituation to taste stimuli in healthy women
    Angela Wagner
    University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, PA 15213, USA
    Psychiatry Res 147:57-67. 2006
    ..By contrast, for sequential blocks, both stimuli produced habituation in taste-related brain regions. These data suggest that habituation patterns in healthy subjects may depend on frequency and regularity of stimulus administration...
  37. doi request reprint Serotonin: imaging findings in eating disorders
    Ursula F Bailer
    Department of Psychiatry and Psychotherapy, Division of Biological Psychiatry, Medical University of Vienna, Austria
    Curr Top Behav Neurosci 6:59-79. 2011
    ..Effective treatments for AN and BN have been elusive. A better understanding of neurobiology is likely to be important for developing specific and more powerful therapies for these often chronic and deadly disorders...