Neurocircuity of eating disordersWalter H Kaye
Department of Psychiatry, University of California, San Diego, CA, USA
Curr Top Behav Neurosci 6:37-57. 2011
..Better understanding of neurocircuits that may be related to altered appetite, mood, impulse control, and other symptoms underlying the pathophysiology of EDs might improve psychotherapeutic and drug treatment strategies...
Sexual functioning in women with eating disordersAndrea Poyastro Pinheiro
Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, USA
Int J Eat Disord 43:123-9. 2010
..To describe sexual functioning in women with eating disorders...
- Posttraumatic stress disorder in anorexia nervosa
Mae Lynn Reyes-Rodríguez
Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
Psychosom Med 73:491-7. 2011
..The main objectives of this study were to describe the nature of traumatic events experienced and to explore the relationship between PTSD and anorexia nervosa (AN) in a sample of women...
- Substance use disorders in women with anorexia nervosa
Tammy L Root
Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
Int J Eat Disord 43:14-21. 2010
..Secondary analyses examined SUD related to lifetime purging behavior and lifetime binge eating...
- Suicide attempts in anorexia nervosa
Cynthia M Bulik
Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
Psychosom Med 70:378-83. 2008
..To explore prevalence and patterns of suicidal attempts in persons with anorexia nervosa (AN)...
- Influence of overanxious disorder of childhood on the expression of anorexia nervosa
T J Raney
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
Int J Eat Disord 41:326-32. 2008
..This study investigates the prevalence of overanxious disorder (OAD) among women with AN and explores how OAD impacts AN symptoms and personality traits...
- Childhood anxiety associated with low BMI in women with anorexia nervosa
Jocilyn E Dellava
Department of Psychiatry, University of North Carolina at Chapel Hill, 101 Manning Drive, CB 7160, Chapel Hill, NC 27599 7160, USA
Behav Res Ther 48:60-7. 2010
..The present study explores childhood personality characteristics that could be associated with the ability to attain an extremely low BMI...
- Understanding the association of impulsivity, obsessions, and compulsions with binge eating and purging behaviours in anorexia nervosa
Elizabeth R Hoffman
Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA
Eur Eat Disord Rev 20:e129-36. 2012
..To further refine our understanding of impulsivity, obsessions, and compulsions in anorexia nervosa (AN) by isolating which behaviours--binge eating, purging, or both--are associated with these features...
- Association study of 182 candidate genes in anorexia nervosa
Andrea Poyastro Pinheiro
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
Am J Med Genet B Neuropsychiatr Genet 153:1070-80. 2010
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- Life beyond the eating disorder: education, relationships, and reproduction
Millie Maxwell
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
Int J Eat Disord 44:225-32. 2011
..We investigated the sociodemographic characteristics in women with and without lifetime eating disorders...
- Altered striatal response to reward in bulimia nervosa after recovery
Angela Wagner
Department of Psychiatry, School of Medicine, University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
Int J Eat Disord 43:289-94. 2010
..It is possible that disturbances of systems modulating reward may contribute to a vulnerability to develop an eating disorder...
Altered insula response to taste stimuli in individuals recovered from restricting-type anorexia nervosaAngela Wagner
Department of Psychiatry, School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA 15213, USA
Neuropsychopharmacology 33:513-23. 2008
..These data provide the first evidence that individuals with AN process taste stimuli differently than controls, based on differences in neural activation patterns...
- Regional cerebral blood flow after recovery from anorexia or bulimia nervosa
Guido K Frank
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Int J Eat Disord 40:488-92. 2007
..Abnormalities of regional cerebral blood flow (rCBF) have been found in individuals who are ill with anorexia (AN) or bulimia nervosa (BN). Little is known about whether rCBF normalizes after recovery from AN and BN...
- Temporal patterns of recovery across eating disorder subtypes
Ann Von Holle
Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
Aust N Z J Psychiatry 42:108-17. 2008
..To compare patterns of recovery in individuals with index episodes of anorexia nervosa (AN) and bulimia nervosa (BN)...
- An examination of early childhood perfectionism across anorexia nervosa subtypes
Katherine A Halmi
Department of Psychiatry, Weill Cornell Medical College, NY, USA
Int J Eat Disord 45:800-7. 2012
..To examine childhood perfectionism in anorexia nervosa (AN) restricting (RAN), purging (PAN), and binge eating with or without purging (BAN) subtypes...
- New insights into symptoms and neurocircuit function of anorexia nervosa
Walter H Kaye
Eating Disorder Treatment and Research Program, Department of Psychiatry, University of California, San Diego, La Jolla Village Professional Center, 8950 Villa La Jolla Drive, Suite C 207, La Jolla, California 92037, USA
Nat Rev Neurosci 10:573-84. 2009
..For example, altered insula activity could explain interoceptive dysfunction, and altered striatal activity might shed light on altered reward modulation in people with anorexia nervosa...
- 5HT2A receptor binding is increased in borderline personality disorder
Paul H Soloff
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Biol Psychiatry 62:580-7. 2007
..We examined 5HT(2A) receptor binding potential (BP) in impulsive subjects with BPD, with positron emission tomography neuroimaging with [(18)F] altanserin...
- Altered insula activation during pain anticipation in individuals recovered from anorexia nervosa: evidence of interoceptive dysregulation
Irina A Strigo
Department of Psychiatry, University of California San Diego, 3350 La Jolla Village Dr, Building 13, MC 9151 B, La Jolla, CA 92161, USA
Int J Eat Disord 46:23-33. 2013
..Pain is an interoceptive process with well-characterized neuroanatomical pathways that may overlap to a large degree with neural systems that may be dysregulated in individuals with AN, such as the insula...
- Differential weight restoration on olanzapine versus fluoxetine in identical twins with anorexia nervosa
Vikas Duvvuri
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92037, USA
Int J Eat Disord 45:294-7. 2012
..No studies have compared the response to selective serotonin reuptake inhibitors and atypical antipsychotics in anorexia nervosa. This case study examines such a comparison...
- Exaggerated 5-HT1A but normal 5-HT2A receptor activity in individuals ill with anorexia nervosa
Ursula F Bailer
Department of Psychiatry, Western Psychiatric Institute and Clinic, School of Medicine, Pittsburgh, University of Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 61:1090-9. 2007
..Because little is known about 5-HT receptor function in AN, positron emission tomography (PET) imaging with 5-HT receptor-specific radioligands was used to characterize 5-HT1A and 5-HT2A receptors...
- Sucrose activates human taste pathways differently from artificial sweetener
Guido K W Frank
University of Colorado at Denver and Health Sciences Center, Department of Psychiatry, The Children s Hospital, Aurora, CO 80045, USA
Neuroimage 39:1559-69. 2008
..This could have important implications on how effective artificial sweeteners are in their ability to substitute sugar intake...
- Patterns of menstrual disturbance in eating disorders
Andréa Poyastro Pinheiro
Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
Int J Eat Disord 40:424-34. 2007
..To describe menstrual disturbance in eating disorders (ED)...
- Cognitive set-shifting in anorexia nervosa
Megan E Shott
Department of Psychiatry, University of Colorado Denver, CO, USA
Eur Eat Disord Rev 20:343-9. 2012
..Adult anorexia nervosa (AN) is associated with inefficient cognitive flexibility and set-shifting. Whether such inefficiencies also characterize adolescent AN is an important area of research...
- Nothing tastes as good as skinny feels: the neurobiology of anorexia nervosa
Walter H Kaye
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Trends Neurosci 36:110-20. 2013
..An understanding of the neurobiology of this disorder is likely to be important for developing more effective treatments...
- Postpartum and depression status are associated with lower [[¹¹C]raclopride BP(ND) in reproductive-age women
Eydie L Moses-Kolko
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Neuropsychopharmacology 37:1422-32. 2012
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- Demand-specific alteration of medial prefrontal cortex response during an inhibition task in recovered anorexic women
Tyson A Oberndorfer
Department of Psychiatry, University of California San Diego, La Jolla, CA 92037, USA
Int J Eat Disord 44:1-8. 2011
..It is well known that individuals with anorexia nervosa (AN) are inhibited and over-controlled. This study investigated a prefrontal-cingulate network that is involved in inhibitory control...
- Aripiprazole in anorexia nervosa and low-weight bulimia nervosa: case reports
Mary Ellen Trunko
Department of Psychiatry, University of California San Diego, San Diego, California, USA
Int J Eat Disord 44:269-75. 2011
..However, newer, more weight-neutral medications have not been studied in AN, and there are no reports of the use of antipsychotics in bulimia nervosa (BN)...
- Smoking in eating disorders
Doris Anzengruber
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7160, USA
Eat Behav 7:291-9. 2006
..Given the high prevalence, the impact of ongoing smoking on maintenance of eating disorders symptoms is worthy of both clinical and research attention...
- An innovative short-term, intensive, family-based treatment for adolescent anorexia nervosa: case series
Roxanne E Rockwell
University of California, San Diego, Department of Psychiatry, La Jolla, CA, USA
Eur Eat Disord Rev 19:362-7. 2011
..Ages of the adolescents in the programme ranged from 10 to 18 years (mean = 15.0, SD = 2.1). We report the outcomes of the first 19 cases...
- Neural correlates of habituation to taste stimuli in healthy women
Angela Wagner
University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, PA 15213, USA
Psychiatry Res 147:57-67. 2006
..By contrast, for sequential blocks, both stimuli produced habituation in taste-related brain regions. These data suggest that habituation patterns in healthy subjects may depend on frequency and regularity of stimulus administration...
- Serotonin: imaging findings in eating disorders
Ursula F Bailer
Department of Psychiatry and Psychotherapy, Division of Biological Psychiatry, Medical University of Vienna, Austria
Curr Top Behav Neurosci 6:59-79. 2011
..Effective treatments for AN and BN have been elusive. A better understanding of neurobiology is likely to be important for developing specific and more powerful therapies for these often chronic and deadly disorders...
