LAWRENCE M KAUVAR

Summary

Publications

  1. doi request reprint A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types
    LAWRENCE M KAUVAR
    Trellis Bioscience, Menlo Park, California, USA
    Antimicrob Agents Chemother 59:1558-68. 2015
  2. pmc Therapeutic targeting of respiratory syncytial virus G-protein
    LAWRENCE M KAUVAR
    Trellis Bioscience, 2 B Corporate Drive, South San Francisco, CA 94080, USA
    Immunotherapy 2:655-61. 2010
  3. doi request reprint Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients
    ELLEN J COLLARINI
    Trellis Bioscience, South San Francisco, CA 94080, USA
    J Immunol 183:6338-45. 2009

Collaborators

Detail Information

Publications3

  1. doi request reprint A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types
    LAWRENCE M KAUVAR
    Trellis Bioscience, Menlo Park, California, USA
    Antimicrob Agents Chemother 59:1558-68. 2015
    ..Further, TRL345 was effective at controlling an ex vivo infection of human placental anchoring villi. TRL345 has been utilized on a commercial scale and is a candidate for clinical evaluation. ..
  2. pmc Therapeutic targeting of respiratory syncytial virus G-protein
    LAWRENCE M KAUVAR
    Trellis Bioscience, 2 B Corporate Drive, South San Francisco, CA 94080, USA
    Immunotherapy 2:655-61. 2010
    ..This objective encompasses a dual mechanism: reduction in the ability of RSV G-protein to distort the host innate immune response, and direct complement-mediated antiviral activity...
  3. doi request reprint Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients
    ELLEN J COLLARINI
    Trellis Bioscience, South San Francisco, CA 94080, USA
    J Immunol 183:6338-45. 2009
    ..The combination of activity in mouse models for both prophylaxis and treatment makes these high-affinity human-derived Abs promising candidates for human clinical testing...