LAWRENCE M KAUVAR

Summary

Publications

  1. pmc A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types
    LAWRENCE M KAUVAR
    Trellis Bioscience, Menlo Park, California, USA
    Antimicrob Agents Chemother 59:1558-68. 2015
  2. pmc Therapeutic targeting of respiratory syncytial virus G-protein
    LAWRENCE M KAUVAR
    Trellis Bioscience, 2 B Corporate Drive, South San Francisco, CA 94080, USA
    Immunotherapy 2:655-61. 2010
  3. doi request reprint Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta
    Takako Tabata
    Department of Cell and Tissue Biology, School of Dentistry, University of California, San Francisco, San Francisco, California, USA
    J Virol 89:5134-47. 2015
  4. doi request reprint Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients
    ELLEN J COLLARINI
    Trellis Bioscience, South San Francisco, CA 94080, USA
    J Immunol 183:6338-45. 2009

Collaborators

  • Ralph A Tripp
  • F Eun Hyung Lee
  • Edward E Walsh
  • Larry J Anderson
  • Takako Tabata
  • ELLEN J COLLARINI
  • Matthew Gormley
  • Matthew Petitt
  • June Fang-Hoover
  • Nicholas Larocque
  • Lenore Pereira
  • Mitsuru Tsuge
  • Martin Zydek
  • Gizette Sperinde
  • Hai Wu
  • Minha Park
  • Bruce A Keyt
  • Orit Foord
  • Stote L Ellsworth
  • Stephen F Carroll
  • William D Harriman

Detail Information

Publications4

  1. pmc A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types
    LAWRENCE M KAUVAR
    Trellis Bioscience, Menlo Park, California, USA
    Antimicrob Agents Chemother 59:1558-68. 2015
    ..Further, TRL345 was effective at controlling an ex vivo infection of human placental anchoring villi. TRL345 has been utilized on a commercial scale and is a candidate for clinical evaluation. ..
  2. pmc Therapeutic targeting of respiratory syncytial virus G-protein
    LAWRENCE M KAUVAR
    Trellis Bioscience, 2 B Corporate Drive, South San Francisco, CA 94080, USA
    Immunotherapy 2:655-61. 2010
    ..This objective encompasses a dual mechanism: reduction in the ability of RSV G-protein to distort the host innate immune response, and direct complement-mediated antiviral activity...
  3. doi request reprint Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta
    Takako Tabata
    Department of Cell and Tissue Biology, School of Dentistry, University of California, San Francisco, San Francisco, California, USA
    J Virol 89:5134-47. 2015
    ..In cases of congenital infection, reduced responsiveness of the placenta to hypoxia limits the transport of substances from maternal blood and contributes to fetal growth restriction...
  4. doi request reprint Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients
    ELLEN J COLLARINI
    Trellis Bioscience, South San Francisco, CA 94080, USA
    J Immunol 183:6338-45. 2009
    ..The combination of activity in mouse models for both prophylaxis and treatment makes these high-affinity human-derived Abs promising candidates for human clinical testing...