Deepak Kaul

Summary

Publications

  1. request reprint
    Kaul D. Cellular AATF gene: armour against HIV-1. Indian J Biochem Biophys. 2007;44:276-8 pubmed
    ....
  2. Kaul D, Sasikala M, Raina A. Regulatory role of miR-2909 in cell-mediated immune response. Cell Biochem Funct. 2012;30:500-4 pubmed publisher
    ..Based upon these results, we propose that miR-2909 may modulate native immunity in general and help in providing protective immunity against viral infections in particular. ..
  3. Kaul D, Malik D, Wani S. Cellular miR-2909 RNomics governs the genes that ensure immune checkpoint regulation. Mol Cell Biochem. 2018;: pubmed publisher
    ..Based upon these findings, we propose a pathway that links miR-2909 RNomics with the genes coding for immune checkpoint regulators required for the maintenance of immune homeostasis. ..
  4. request reprint
    Kaul D. Cholesterol-receptor-mediated genomics in health and disease. Trends Mol Med. 2003;9:442-9 pubmed
    ....
  5. Malik D, Kaul D, Chauhan N, Marwaha R. miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias. Mol Cancer. 2014;13:175 pubmed publisher
    ..This study identified a novel miR-2909-KLF4 molecular axis able to differentiate between the pathogeneses of pediatric B- and T-cell ALLs, and which may represent a new diagnostic/prognostic marker. ..
  6. Kaul D, Arora M, Garg A, Sharma S. MALT1 induced immune response is governed by miR-2909 RNomics. Mol Immunol. 2015;64:210-7 pubmed publisher
    ..Based upon these results, a mechanistic-pathway is proposed that links the epigenomic-interplay between MALT1 and miR-2909. ..
  7. Kaul D, Sharma S. High glucose-induced human cellular immune response is governed by miR-2909 RNomics. Blood Cells Mol Dis. 2015;54:342-7 pubmed publisher
    ..Based upon these results an attempt was also made to propose a mechanistic pathway that links high glucose induced cellular miR-2909 RNomics with the genes involved in energy metabolism and immune response. ..
  8. Kaul D, Sharma S, Garg A. Mitochondrial uncoupling protein (UCP2) gene expression is regulated by miR-2909. Blood Cells Mol Dis. 2015;55:89-93 pubmed publisher
    ....
  9. Sikand K, Kaul D, Varma N. Receptor Ck-dependent signaling regulates hTERT gene transcription. BMC Cell Biol. 2006;7:2 pubmed
    ....
  10. request reprint
    Kaul D, Sikand K. Defective RNA-mediated c-myc gene silencing pathway in Burkitt's lymphoma. Biochem Biophys Res Commun. 2004;313:552-4 pubmed
    ..Based on these findings we have proposed a novel RNA-mediated c-myc gene regulation pathway that may be responsible for BL. ..

Locale

Detail Information

Publications14

  1. request reprint
    Kaul D. Cellular AATF gene: armour against HIV-1. Indian J Biochem Biophys. 2007;44:276-8 pubmed
    ....
  2. Kaul D, Sasikala M, Raina A. Regulatory role of miR-2909 in cell-mediated immune response. Cell Biochem Funct. 2012;30:500-4 pubmed publisher
    ..Based upon these results, we propose that miR-2909 may modulate native immunity in general and help in providing protective immunity against viral infections in particular. ..
  3. Kaul D, Malik D, Wani S. Cellular miR-2909 RNomics governs the genes that ensure immune checkpoint regulation. Mol Cell Biochem. 2018;: pubmed publisher
    ..Based upon these findings, we propose a pathway that links miR-2909 RNomics with the genes coding for immune checkpoint regulators required for the maintenance of immune homeostasis. ..
  4. request reprint
    Kaul D. Cholesterol-receptor-mediated genomics in health and disease. Trends Mol Med. 2003;9:442-9 pubmed
    ....
  5. Malik D, Kaul D, Chauhan N, Marwaha R. miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias. Mol Cancer. 2014;13:175 pubmed publisher
    ..This study identified a novel miR-2909-KLF4 molecular axis able to differentiate between the pathogeneses of pediatric B- and T-cell ALLs, and which may represent a new diagnostic/prognostic marker. ..
  6. Kaul D, Arora M, Garg A, Sharma S. MALT1 induced immune response is governed by miR-2909 RNomics. Mol Immunol. 2015;64:210-7 pubmed publisher
    ..Based upon these results, a mechanistic-pathway is proposed that links the epigenomic-interplay between MALT1 and miR-2909. ..
  7. Kaul D, Sharma S. High glucose-induced human cellular immune response is governed by miR-2909 RNomics. Blood Cells Mol Dis. 2015;54:342-7 pubmed publisher
    ..Based upon these results an attempt was also made to propose a mechanistic pathway that links high glucose induced cellular miR-2909 RNomics with the genes involved in energy metabolism and immune response. ..
  8. Kaul D, Sharma S, Garg A. Mitochondrial uncoupling protein (UCP2) gene expression is regulated by miR-2909. Blood Cells Mol Dis. 2015;55:89-93 pubmed publisher
    ....
  9. Sikand K, Kaul D, Varma N. Receptor Ck-dependent signaling regulates hTERT gene transcription. BMC Cell Biol. 2006;7:2 pubmed
    ....
  10. request reprint
    Kaul D, Sikand K. Defective RNA-mediated c-myc gene silencing pathway in Burkitt's lymphoma. Biochem Biophys Res Commun. 2004;313:552-4 pubmed
    ..Based on these findings we have proposed a novel RNA-mediated c-myc gene regulation pathway that may be responsible for BL. ..
  11. request reprint
    Kaul D, Shukla A, Sikand K, Dhawan V. Effect of herbal polyphenols on atherogenic transcriptome. Mol Cell Biochem. 2005;278:177-84 pubmed
    ..On the basis of these results, we propose for the first time that HPLC purified polyphenolic fraction IV of Tulsi may have a profound antiatherogenic effect. ..
  12. request reprint
    Kaul D, Anand P, Khanna A. Functional genomics of PPAR-gamma in human immunomodulatory cells. Mol Cell Biochem. 2006;290:211-5 pubmed
    ..Based on these results, we propose that PPAR-gamma gene has the inherent capacity to influence the lipid mediated inflammation process in atherosclerotic lesions. ..
  13. request reprint
    Kaul D, Mehrotra A. Functional characterization of AATF transcriptome in human leukemic cells. Mol Cell Biochem. 2007;297:215-20 pubmed
    ..Based on these results we propose that AATF gene may be of crucial importance in maintaining the leukemic state of a cell compartment through its ability to initiate cell proliferation coupled with repression of cellular apoptosis. ..
  14. Wani S, Kaul D, Mavuduru R, Kakkar N, Bhatia A. Urinary-exosomal miR-2909: A novel pathognomonic trait of prostate cancer severity. J Biotechnol. 2017;259:135-139 pubmed publisher
    ..In summary, we propose that the extent of urinary exosomal miR-2909 recruitment may provide a potential non-invasive candidate diagnostic marker for the detection of prostate cancer and its aggressiveness. ..