Nathaniel Katz

Summary

Publications

  1. ncbi request reprint Onset of pain relief with rofecoxib in chronic low back pain: results of two four-week, randomized, placebo-controlled trials
    Nathaniel Katz
    Harvard Medical School, Boston, Massachusetts 02464, USA
    Curr Med Res Opin 20:651-8. 2004
  2. ncbi request reprint Methodological issues in clinical trials of opioids for chronic pain
    Nathaniel Katz
    Tufts University School of Medicine, Boston, MA, USA
    Neurology 65:S32-49. 2005
  3. ncbi request reprint A 12-week, randomized, placebo-controlled trial assessing the safety and efficacy of oxymorphone extended release for opioid-naive patients with chronic low back pain
    Nathaniel Katz
    Tufts University School of Medicine, Boston, MA, USA
    Curr Med Res Opin 23:117-28. 2007
  4. ncbi request reprint Preliminary development of a responder index for chronic low back pain
    Lee S Simon
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02465, USA
    J Rheumatol 34:1386-91. 2007
  5. ncbi request reprint Role of urine toxicology testing in the management of chronic opioid therapy
    Nathaniel Katz
    Pain Trials Center, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Clin J Pain 18:S76-82. 2002
  6. ncbi request reprint Efficacy and safety of rofecoxib in patients with chronic low back pain: results from two 4-week, randomized, placebo-controlled, parallel-group, double-blind trials
    Nathaniel Katz
    Pain Trials Center, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Spine (Phila Pa 1976) 28:851-8; discussion 859. 2003
  7. ncbi request reprint Opioids for neuropathic pain
    Nathaniel Katz
    Inflexxion, Inc, 320 Needham Street, Suite 100, Newton, MA 02464, USA
    Curr Pain Headache Rep 9:153-60. 2005
  8. doi request reprint Measuring attractiveness for abuse of prescription opioids
    Stephen F Butler
    Inflexxion, Inc, Newton, Massachusetts, USA
    Pain Med 11:67-80. 2010
  9. doi request reprint Morphine sulfate and naltrexone hydrochloride extended release capsules in patients with chronic osteoarthritis pain
    Nathaniel Katz
    Tufts University School of Medicine, Boston, MA, USA
    Postgrad Med 122:112-28. 2010
  10. doi request reprint Update on prescription monitoring in clinical practice: a survey study of prescription monitoring program administrators
    Nathaniel Katz
    Inflexxion, Inc, Newton, Massachusetts 02464, USA
    Pain Med 9:587-94. 2008

Detail Information

Publications31

  1. ncbi request reprint Onset of pain relief with rofecoxib in chronic low back pain: results of two four-week, randomized, placebo-controlled trials
    Nathaniel Katz
    Harvard Medical School, Boston, Massachusetts 02464, USA
    Curr Med Res Opin 20:651-8. 2004
    ..The objectives of this report are to present data regarding the onset of efficacy of rofecoxib from these trials and propose methods for reporting onset...
  2. ncbi request reprint Methodological issues in clinical trials of opioids for chronic pain
    Nathaniel Katz
    Tufts University School of Medicine, Boston, MA, USA
    Neurology 65:S32-49. 2005
    ..Opioid analgesics should be studied in a manner that is clinically relevant, and that supports internal validity. More systematic attention is needed to clinical research methodology...
  3. ncbi request reprint A 12-week, randomized, placebo-controlled trial assessing the safety and efficacy of oxymorphone extended release for opioid-naive patients with chronic low back pain
    Nathaniel Katz
    Tufts University School of Medicine, Boston, MA, USA
    Curr Med Res Opin 23:117-28. 2007
    ..Determine the efficacy and tolerability of oxymorphone extended release (OPANA ER) in opioid-naive patients with moderate to severe chronic low back pain (CLBP)...
  4. ncbi request reprint Preliminary development of a responder index for chronic low back pain
    Lee S Simon
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02465, USA
    J Rheumatol 34:1386-91. 2007
    ..The aim of the OMERACT Special Interest Group was to discuss the development and validation of a preliminary responder index in CLBP...
  5. ncbi request reprint Role of urine toxicology testing in the management of chronic opioid therapy
    Nathaniel Katz
    Pain Trials Center, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Clin J Pain 18:S76-82. 2002
    ..The authors conclude that, although further research is urgently needed, at this time it is appropriate to conduct routine urine toxicology testing in patients with chronic pain treated with opioids...
  6. ncbi request reprint Efficacy and safety of rofecoxib in patients with chronic low back pain: results from two 4-week, randomized, placebo-controlled, parallel-group, double-blind trials
    Nathaniel Katz
    Pain Trials Center, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Spine (Phila Pa 1976) 28:851-8; discussion 859. 2003
    ..Two replicate, 4-week, randomized, double-blind, placebo-controlled, trials of rofecoxib 25 and 50 mg versus placebo for chronic low back pain...
  7. ncbi request reprint Opioids for neuropathic pain
    Nathaniel Katz
    Inflexxion, Inc, 320 Needham Street, Suite 100, Newton, MA 02464, USA
    Curr Pain Headache Rep 9:153-60. 2005
    ..Opioids have an important role in the treatment of neuropathic pain; however, skillful opioid use balances the benefits with management of side effects and prevention and treatment of abuse and addiction...
  8. doi request reprint Measuring attractiveness for abuse of prescription opioids
    Stephen F Butler
    Inflexxion, Inc, Newton, Massachusetts, USA
    Pain Med 11:67-80. 2010
    ....
  9. doi request reprint Morphine sulfate and naltrexone hydrochloride extended release capsules in patients with chronic osteoarthritis pain
    Nathaniel Katz
    Tufts University School of Medicine, Boston, MA, USA
    Postgrad Med 122:112-28. 2010
    ....
  10. doi request reprint Update on prescription monitoring in clinical practice: a survey study of prescription monitoring program administrators
    Nathaniel Katz
    Inflexxion, Inc, Newton, Massachusetts 02464, USA
    Pain Med 9:587-94. 2008
    ..The purpose of this study was to provide a benchmark of the current status of PMPs for healthcare providers upon which to engage PMP administrators...
  11. doi request reprint Estimating attractiveness for abuse of a not-yet-marketed "abuse-deterrent" prescription opioid formulation
    Stephen F Butler
    Inflexxion, Inc, Newton, Massachusetts 02464, USA
    Pain Med 11:81-91. 2010
    ..A second online sample rated the extent to which these features applied to particular products they had actually used/abused. These data were used to model the abusers' overall preference for prescription opioids they had used/abused...
  12. doi request reprint Development of a budget-impact model to quantify potential cost savings from prescription opioids designed to deter abuse or ease of extraction
    Alan G White
    Analysis Group, Inc, Boston, Massachusetts, USA
    Appl Health Econ Health Policy 7:61-70. 2009
    ..As well as public health and safety benefits, use of an abuse-deterrent/resistant RxO (ADO) that may deter abuse, dependence and misuse could also generate cost savings...
  13. doi request reprint ALO-01 (morphine sulfate and naltrexone hydrochloride) extended-release capsules in the treatment of chronic pain of osteoarthritis of the hip or knee: pharmacokinetics, efficacy, and safety
    Nathaniel Katz
    Tufts University School of Medicine, Boston, Massachusetts Analgesic Research, Needham, MA 02494, USA
    J Pain 11:303-11. 2010
    ..Results highlight the potential for morphine in ALO-01 to manage moderate-to-severe osteoarthritis pain, while the sequestered naltrexone does not interfere with efficacy...
  14. pmc Development and validation of the Current Opioid Misuse Measure
    Stephen F Butler
    Inflexxion, Inc, Newton, MA 02464, USA
    Pain 130:144-56. 2007
    ..The COMM was found to have promise as a brief, self-report measure of current aberrant drug-related behavior. Further cross-validation and replication of these preliminary results is pending...
  15. ncbi request reprint Internet surveillance: content analysis and monitoring of product-specific internet prescription opioid abuse-related postings
    Stephen F Butler
    Inflexxion, Inc, Newton, MA 02464, USA
    Clin J Pain 23:619-28. 2007
    ..This study describes the development of a systematic approach to the analysis of Internet chatter as a means of monitoring potentially abusable opioid analgesics...
  16. doi request reprint Internet-based survey of nonmedical prescription opioid use in the United States
    Nathaniel Katz
    Inflexxion Inc, Newton, MA 02464, USA
    Clin J Pain 24:528-35. 2008
    ..An Internet-based survey of nonmedical opioid users visiting informational drug websites was used to measure rates of nonmedical use and characterize users...
  17. doi request reprint Illustration of a statistical process control approach to regional prescription opioid abuse surveillance
    James C Benneyan
    Center for Health Organization Transformation, Northeastern University, Boston, MA, USA
    J Addict Med 5:99-109. 2011
    ..To investigate and illustrate the use of statistical process control (SPC) for prospective monitoring and detection of regional changes in prescription opioid abuse rates...
  18. ncbi request reprint Coxibs: Evolving role in pain management
    Nathaniel Katz
    Department of Anesthesia, Harvard Medical School, Boston, MA, USA
    Semin Arthritis Rheum 32:15-24. 2002
    ..Decreased GI and antiplatelet effects of coxibs compared to traditional NSAIDs provide the potential to incorporate coxibs into the pain management algorithm used to treat cancer pain...
  19. doi request reprint Usefulness of prescription monitoring programs for surveillance--analysis of Schedule II opioid prescription data in Massachusetts, 1996-2006
    Nathaniel Katz
    Tufts University School of Medicine, Boston, MA 02111, USA
    Pharmacoepidemiol Drug Saf 19:115-23. 2010
    ..We analyze herein 11 years of Massachusetts PMP data to evaluate trends in opioid prescribing, dispensing, and usage...
  20. doi request reprint Enriched enrollment randomized withdrawal trial designs of analgesics: focus on methodology
    Nathaniel Katz
    Analgesic Research, Needham, MA, 02494, USA
    Clin J Pain 25:797-807. 2009
    ..To systematically identify and critically assess clinical trials that use enriched enrollment randomized withdrawal (EERW) trial design as a methodology for assessing the effect of analgesics pain...
  21. doi request reprint National addictions vigilance intervention and prevention program (NAVIPPRO): a real-time, product-specific, public health surveillance system for monitoring prescription drug abuse
    Stephen F Butler
    Inflexxion, Inc, Newton, MA 02464 1594, USA
    Pharmacoepidemiol Drug Saf 17:1142-54. 2008
    ....
  22. doi request reprint Tampering with prescription opioids: nature and extent of the problem, health consequences, and solutions
    Nathaniel Katz
    Analgesic Solutions, Natick, MA, USA
    Am J Drug Alcohol Abuse 37:205-17. 2011
    ..Transdermal and solid oral prescription opioid (PO) formulations can be abused by ingesting (with or without tampering), snorting, or injection (both requiring tampering)...
  23. doi request reprint Ultrasound-enabled topical anesthesia for pain reduction of phlebotomy for whole blood donation
    Christopher P Stowell
    Department of Pathology, Blood Transfusion Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Transfusion 49:146-53. 2009
    ..Ultrasound-facilitated delivery of topical anesthetics has been used to achieve effective anesthesia within 5 minutes for venipuncture and the insertion of intravenous access devices, but has never been studied for blood donation...
  24. doi request reprint The impact of opioids on the endocrine system
    Nathaniel Katz
    Analgesic Research, Tufts University School of Medicine, Boston, MA, USA
    Clin J Pain 25:170-5. 2009
    ..However, their negative effects on the endocrine system, which have been known for some times, are barely discussed in modern medicine. Therefore, we conducted a systematic review of the impact of opioids on the endocrine system...
  25. ncbi request reprint Direct costs of opioid abuse in an insured population in the United States
    Alan G White
    Analysis Group, Inc, 111 Huntington Ave, 10th Fl, Boston, MA 02199, USA
    J Manag Care Pharm 11:469-79. 2005
    ..g., inpatient, outpatient, emergency room, drug, other) from the perspective of a private payer...
  26. ncbi request reprint The impact of pain management on quality of life
    Nathaniel Katz
    Pain Trials Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Pain Symptom Manage 24:S38-47. 2002
    ....
  27. ncbi request reprint Treatment of postherpetic neuralgia: a review of therapeutic options
    Charles E Argoff
    Cohn Pain Management Center, North Shore University Hospital, Cohn Pain Management Center, Bethpage, New York 11714, USA
    J Pain Symptom Manage 28:396-411. 2004
    ..Well-designed, multicenter, controlled clinical trials are needed to develop a treatment algorithm that provides an evidence-based, rational approach to treating PHN...
  28. ncbi request reprint Relative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain
    Lowell Reynolds
    Center for Pain Management, Loma Linda University School of Medicine, Loma Linda, CA, USA
    Pain 110:182-8. 2004
    ..5; mean potency ratio was 7.44 (95% confidence interval 6.8-8.2). During titrated, intermediate-term infusions in patients previously treated with opioids for chronic pain, sufentanil is approximately 7.5 times as potent as fentanyl...
  29. ncbi request reprint Reporting of clinical trials of analgesia
    Nathaniel Katz
    J Thorac Cardiovasc Surg 127:605; author reply 606. 2004
  30. ncbi request reprint Opioids: after thousands of years, still getting to know you
    Nathaniel Katz
    Analgesic Research, Needham, MA 02494, USA
    Clin J Pain 23:303-6. 2007
  31. ncbi request reprint Abuse-deterrent opioid formulations: are they a pipe dream?
    Nathaniel Katz
    Analgesic Research, 109 Highland Avenue, Suite B2, Needham, MA 02494, USA
    Curr Rheumatol Rep 10:11-8. 2008
    ....