Candida A L Kassuya



  1. da Silva Moreira S, Tamashiro L, Jorge B, da Silva Balin P, Heredia Vieira S, de Almeida G, et al. Toxicological safety evaluation in acute and 28-day studies of aqueous extract from Serjania marginata Casar. (Sapindaceae) leaves in rats. J Ethnopharmacol. 2019;231:197-204 pubmed publisher
    ..Although AESM was not toxic after a single exposure, its use after prolonged periods affected some analyzed parameters, indicating that precautions should be taken when it is given over longer periods. ..
  2. de Santana Aquino D, Piccinelli A, Soares F, Arena A, Salvador M, Kassuya C. Anti-hyperalgesic and Anti-inflammatory Activity of Alternanthera Maritima Extract and 2″-O-α-L-rhamnopyranosylvitexin in Mice. Inflammation. 2015;38:2057-66 pubmed publisher
  3. da Silva Balin P, Zanatta F, Jorge B, Leitão M, Kassuya R, Cardoso C, et al. Toxicological evaluation and anti-inflammatory potential of an ethanolic extract from Bromelia balansae (Bromeliaceae) fruit. J Ethnopharmacol. 2018;222:79-86 pubmed publisher
    ..These results show that EEBB has an anti-inflammatory potential without causing acute or subacute toxicity. These data may contribute to the advancement of biopharmaceutical applications for this species. ..
  4. da Silva Arrigo J, Balen E, Júnior U, da Silva Mota J, Iwamoto R, Barison A, et al. Anti-nociceptive, anti-hyperalgesic and anti-arthritic activity of amides and extract obtained from Piper amalago in rodents. J Ethnopharmacol. 2016;179:101-9 pubmed publisher
    ..amalago. ..
  5. Ishikawa R, Vani J, das Neves S, Rabacow A, Kassuya C, Croda J, et al. The safe use of Doliocarpus dentatus in the gestational period: Absence of changes in maternal reproductive performance, embryo-fetal development and DNA integrity. J Ethnopharmacol. 2018;217:1-6 pubmed publisher
    ..the EEDd do not alter the reproductive parameters, embryofetal development and DNA integrity, ensuring its safe use during pregnancy. ..
  6. Piccinelli A, Morato P, Dos Santos Barbosa M, Croda J, Sampson J, Kong X, et al. Limonene reduces hyperalgesia induced by gp120 and cytokines by modulation of IL-1 ? and protein expression in spinal cord of mice. Life Sci. 2017;174:28-34 pubmed publisher
    ..The ability of limonene to inhibit the mechanical hyperalgesia induced by gp120, TNF-? and IL-1? emphasizes the anti-inflammatory action of limonene, specifically its ability to inhibit cytokine production and its consequences. ..
  7. Branquinho L, Santos J, Cardoso C, Mota J, Júnior U, Kassuya C, et al. Anti-inflammatory and toxicological evaluation of essential oil from Piper glabratum leaves. J Ethnopharmacol. 2017;198:372-378 pubmed publisher
    ..These results demonstrate the anti-inflammatory potential of the essential oil of P. glabratum leaves in the absence of toxicity in female mice. ..
  8. de Paula Vasconcelos P, Spessotto D, Marinho J, Salvador M, Júnior A, Kassuya C. Mechanisms underlying the diuretic effect of Gomphrena celosioides Mart. (Amaranthaceae). J Ethnopharmacol. 2017;202:85-91 pubmed publisher
    ..celosioides. ..
  9. Ishikawa R, Leitão M, Kassuya R, Macorini L, Moreira F, Cardoso C, et al. Anti-inflammatory, antimycobacterial and genotoxic evaluation of Doliocarpus dentatus. J Ethnopharmacol. 2017;204:18-25 pubmed publisher
    ..The EEDd does not display genotoxicity, phagocytosis and could act as an antimycobacterial and anti-inflammatory agent. This study should contribute to ensuring the safe use of EEDd. ..

More Information


  1. do Nascimento K, Moreira F, Alencar Santos J, Kassuya C, Croda J, Cardoso C, et al. Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol. J Ethnopharmacol. 2018;210:351-358 pubmed publisher
    ..guineense (leaves were collected in Dourados-MS) and spathulenol, collaborating the etnhopharmacologycal use of this plant due to its an anti-inflammatory effect. ..
  2. do Santos R, de Souza A, Andrade Silva M, Vera Cruz K, Leite Kassuya C, Lima Cardoso C, et al. Antioxidant, anti-rheumatic and anti-inflammatory investigation of extract and dicentrinone from Duguetia furfuracea (A. St.-Hil.) Benth. & Hook. f. J Ethnopharmacol. 2018;211:9-16 pubmed publisher
    ..furfuracea exhibits antioxidant, anti-rheumatic potential and anti-inflammatory activity. The presence of the alkaloid dicentrinone in extract and CF fraction could be responsible, at least in part, for the observed effects. ..