Research Topics

prof. s mohan Karuppayil

Summary

Affiliation: SRTM University
Location: Nanded, India
Summary:
Research on Quorum sensing, Biofilm formation in Candida albicans.Bioactive samll molecules.Biofabrication nanparticles.
Teaches Biotechnology.

Write Science fiction stories for children.
Publications:
Publications of Prof. S. Mohan Karuppayil in peer-reviewed journals
(2007 to 2013 )

1) Shinde R. B., Rajput S. B., Raut J. S., and Karuppayil S. M. (2013). An in vitro repositioning study reveals antifungal potential of chloroquine to inhibit growth and morphogenesis in Candida albicans. Journal of General and Applied Microbiology. (Accepted for publication). (IF- 1.0).
2) Mangulkar M. P., Routh M. M., Shinde R. B. and Karuppayil S. M. (2013). Ethnic uses of medicinal plants for gynecological care from thirty eight villages of India. Asian Journal of Traditional Medicine. (Accepted for publication).
3) Rajput S. B. and Karuppayil S. M. (2013) Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans. Springer Plus. 2:26 doi:10.1186/2193-1801-2-26.
4) Raut J. S., Shinde R. B., Chauhan N. M. and Karuppayil S. M. (2013). Terpenoids of plant origin inhibits morphogenesis, adhesion and biofilm formation by Candida albicans. Biofouling. 29:87-96. (IF- 4.43)
5) Shinde R. B., Raut J. S., Chauhan N. M. and Karuppayil S. M. (2013). Chloroquine sensitizes biofilms of Candida albicans to antifungal azoles. Brazilian Journal of Infectious Diseases. (Accepted for publication). (IF- 1.04)
6) Routh M. M., Chauhan N. M. and Karuppayil S. M. (2013). Anticancer drugs inhibit morphogenesis in Candida albicans. Brazilian Journal of Microbiology. (Accepted for publication). (IF- 0.96)
7) Chauhan N. M., Shinde, R. B. and Karuppayil S. M. (2013). Alcohols as potential signaling molecules for disseminative mode of growth in Candida albicans. Brazilian Journal of Microbiology. (Accepted for publication). (IF- 0.96)
8) Rajput S. B. and Karuppayil S. M. (2012). β-Asarone, an active principle of Acorus calamus rhizome inhibit growth, morphogenesis and ergosterol biosynthesis in Candida albicans. Phytomedicine. doi:10.1016/j.phymed.2012.09. 029. (IF- 3.3)
9) Rathod V. S., Raut J. S. and Karuppayil S. M. (2012). Antifungal drug susceptibility of Candida albicans isolates from tuberculosis patients. International Journal of Pharmacy and Pharmaceutical Sciences. 4(5):323-326. (IF- 0.38)
10) Rathod V. S., Raut J. S. and Karuppayil S. M. (2012). In vitro antifungal susceptibility reveals occurrence of azole resistance among clinical isolates of Candida albicans. Asian Journal of Pharmaceutical and Clinical Research. 5(3): 170-173. (IF- 0.31)
11) Haleem Khan A. A. and Karuppayil S. M. (2012). Fungal pollution of indoor environments and its management. Saudi Journal of Biological Sciences. 19:405-426. (IF- 0.2)
12) Raut J. S., Shinde R. B. and Karuppayil S. M. (2012). Indole, a bacterial signaling molecule, exhibit inhibitory activity against Candida albicans growth, dimorphism and biofilms. African Journal of Microbiology Research. 6:6005- 6012. (IF- 0.64).
13) Shinde R. B., Raut J. S. and Karuppayil S. M. (2012). Biofilm formation by Candida albicans on various prosthetic materials and its fluconazole sensitivity: A kinetic study. Mycoscience. 53:220-226. (IF- 1.212)
14) Shinde R. B., Chauhan N. M., Raut J. S. and Karuppayil S. M. (2012). Sensitization of Candida albicans biofilms to various antifungal drugs by cyclosporine A. BMC Annals of Clinical Microbiology and Antimicrobials. 11:27. (IF- 1.76).
15) Pathak A. P., Sardar A., Kadam V., Rekadwad B. and Karuppayil S. M. (2012). Efficacy of some medicinal plants against human dental pathogens. Indian Journal of Natural Products and Resources. 3:123-127.
16) Deshmukh K. B., Pathak A. P. and Karuppayil S. M. (2011). Bacterial diversity of Lonar soda lake of India. Indian Journal of Microbiology. 51:107-111. (IF- 0.51)
17) Routh M. M., Raut J. S. and Karuppayil S. M. (2011). Dual properties of anticancer agents: An exploratory study on the in-vitro anti-Candida properties of thirty drugs. Chemotherapy. 57:372-380. (IF- 1.81)
18) Deokar A. A., Kondawar V., Jain P. K., Karuppayil S. M., Raju N. L., Vadez V., Varshney R. K. and Srinivasan R. (2011). Comparative analysis of expressed sequence tags (ESTs) between drought tolerant and susceptible genotypes of chickpea under terminal drought stress. BMC Plant Biology.11:70. (IF- 3.45)
19) Chauhan N. M. Raut J. S. and Karuppayil S. M. (2011). Acetaldehyde inhibits yeast to hyphal form morphogenesis and biofilm formation in Candida albicans. Mycoscience. 52:356-360. (IF- 1.212)
20) Chauhan N. M., Raut J. S. and Karuppayil S. M. (2011). A morphogenetic regulatory role for ethyl alcohol in Candida albicans. Mycoses. 54:e697-e703. (IF- 2.25)
21) Haleem Khan A. A. and Karuppayil S. M. (2011). Practices contributing to biotic pollution in Air- conditioned indoor environments. Aerobiologia. 27:85-89. (IF- 1.51)
22) Zore G. B., Thakre A. D., Jadhav S and Karuppayil S. M. (2011). Terpenoids inhibit Candida albicans growth by affecting membrane integrity and arrest of cell cycle. Phytomedicine. 18:1181-1190. (IF- 3.3)
23) Zore G. B., Thakare A. D., Rathod V. and Karuppayil S. M. (2011). Evaluation of anti-Candida potential of Geranium oil constituents against clinical isolates of Candida albicans differentially sensitive to fluconazole: inhibition of growth, dimorphism and sensitization. Mycoses. 54:e99-e109. (IF- 2.25)
24) Raut J., Rathod V. and Karuppayil S. M. (2010). Cell surface hydrophobicity and adhesion: A study on fifty clinical isolates of Candida albicans. Japanese Journal of Medical Mycology. 51:131-136. (IF- 0.2)
25) Haleem Khan A. A. and Karuppayil S. M. (2010). Potential natural disinfectants for indoor environments. International Journal of Clinical Aromatherapy. 7:1-5.
26) Haleem Khan A. A., Karuppayil S. M. (2010). Manoharachary C., Kunwar I. K. and Waghray S. (2009). Isolation, identification and testing for allergenicity of fungi from air-conditioned indoor environments. Aerobiologia. 25:119-123. (IF- 1.51)
27) Zore, G. B., Winston U. B., Surwase B. S., Mesharam N., Sangle V. D., Kulkarni S. S. and Karuppayil S. M. (2008). Chemoprofile and bioactivites of Taverniera cuneifolia (Roth) Arn.: A wild relative and possible substitute of Glycyrrhiza glabra L. Phytomedicine. 15:292-300. (IF- 3.3)
28) Zore G. B., Awad V., Thakare A. D., Halde U. K., Mesharam N. S., Surwase B. S. and Karuppayil S. M. (2007). Activity-directed fractionation and isolation of four Antibacterial compounds from Abrus precatorius L. roots. Natural Product Research. 21(10):933-940. (IF- 1.009).

Publications

  1. request reprint
    Raut J, Rathod V, Karuppayil S. Cell surface hydrophobicity and adhesion: a study on fifty clinical isolates of Candida albicans. Nihon Ishinkin Gakkai Zasshi. 2010;51:131-6 pubmed
    ..Adherence varied in the range of 79 to 478 cells per microscopic field. Results indicated no correlation between CSH of the clinical isolates and their adhesion to polystyrene. ..
  2. Deshmukh K, Pathak A, Karuppayil M. Bacterial diversity of lonar soda lake of India. Indian J Microbiol. 2011;51:107-11 pubmed publisher
    ..In addition all the eleven bacteria are potential producers of industrially important enzymes, pigments, antibiotics as well. ..
  3. Ali A, Jadhav A, Jangid P, Patil R, Shelar A, Karuppayil S. The human muscarinic acetylcholine receptor antagonist, Dicyclomine targets signal transduction genes and inhibits the virulence factors in the human pathogen, Candida albicans. J Antibiot (Tokyo). 2018;71:456-466 pubmed publisher
    ..Based on this study we suggest that the muscarinic acetylcholine receptor antagonist, dicyclomine could be repositioned as a potential anti-Candida albicans as well as anti-virulence agent. ..
  4. request reprint
    Raut J, Karuppayil S. Phytochemicals as Inhibitors of Candida Biofilm. Curr Pharm Des. 2016;22:4111-34 pubmed
    ..In vivo testing in animal models and clinical trials in humans are required to be taken up seriously to propose few of the phytochemicals as candidate drug molecules. ..
  5. Jadhav A, Bansode B, Phule D, Shelar A, Patil R, Gade W, et al. The antibacterial agent, moxifloxacin inhibits virulence factors of Candida albicans through multitargeting. World J Microbiol Biotechnol. 2017;33:96 pubmed publisher
    ..albicans. In addition chances of developing moxifloxacin resistance in C. albicans are less considering the fact that moxifloxacin may target multiple steps in yeast to hyphal transition in C. albicans. ..
  6. Jadhav A, Karuppayil S. Molecular docking studies on thirteen fluoroquinolines with human topoisomerase II a and b. In Silico Pharmacol. 2016;5:4 pubmed publisher
    ..Our in silico study suggests that fluoroquinolines could be repositioned as DNA topoisomerase II inhibitors hence can be used as anticancer drugs. In vitro and in vivo experiments need to be done to confirm their efficacy. ..

Detail Information

Publications6