Amrinder J Kanwar

..The knowledge of the frequency and significance of these ocular complications may allow their early diagnosis and treatment. The present study assesses the ocular complications in Indian children suffering from AD...

..Lichen planus (LP) is uncommon in children, and there have been few large studies on LP in this patient group. Most of the literature on childhood LP has appeared as case reports or isolated case series...

..Most important distinction is from Kaposi sarcoma and this is mainly histopathological. Here we report a case of acroangiodermatitis in a patient with congenital myopathy and have also discussed its pathogenesis...

..Various treatment modalities have been described to treat pemphigus. In cases where the disease fails to respond to conventional therapy, rituximab has been shown to be effective...

..In this article, we review various aspects of literature on pemphigus in India, on Indians abroad, or literature from other countries that are considered relevant to the topic...

..In this article, we have reviewed the current developments and new found role of the conventional drugs as well as the newer nonbiologic systemic drugs in the treatment of psoriasis...

..We review here the epidemiology, pathogenesis, clinical features, diagnosis, management and prognosis pertaining to lichen planus in children with emphasis on studies published from India...

..Palmar pits are intriguing and are found in association with diverse dermatologic conditions. Some are innocuous, whereas others have sinister implications...

..Azelaic acid (AZA) 20% is considered efficacious in the treatment of melasma, although the response is rather slow. It has also been combined synergistically with topical retinoic acid, where the results were satisfactory...

..Its probable association with surgical trauma is discussed...

..Dexamethasone cyclophosphamide pulse (DCP) therapy is an established mode of treatment for pemphigus in India...

..All were referred to the child guidance clinic and they all showed improvement with behavior therapy. A close liasion between the dermatologist, psychiatrist and parents would go a long way in preventing this alopecia..

..A child with typical acral rash, zinc deficiency and low breast milk zinc levels is described. The importance of awareness of this entity in breast-fed infants along with differential diagnosis is being emphasized...

..There is history of exertional dyspnea, which has been related to her cardiologic ailment. She is not a known diabetic and has no other significant medical history...

..Several clinical variants of Darier disease have been described. Predominant flexural distribution of lesions in Darier disease is uncommon...

..More double-blind trials are required in the future to substantiate and evaluate the role of the drug in these two indications...

..Rarely purpura and fixed drug eruptions have also been observed in adults. We present herein a case of nimesulide-induced fixed drug eruption in a 10-year-old boy. The lesions were extensive and showed cross-sensitivity to sulfonamides...

..Low-dose isotretinoin has been used successfully in mild to moderate papulopustular acne. Although isotretinoin acts against all mechanisms of acne formation, it has no significant direct antimicrobial effect...

..We present two cases of severe angioedema induced by enalapril and ramipril along with possible precipitating factors observed in these patients. The importance of prompt recognition and early management of such cases is emphasized...

..Surgical resection of the affected rib led to complete resolution. Early diagnosis of TB of this rare site and the role of surgical intervention in such cases is emphasized...

..However, it has not been previously reported in patients as young as 2 years of age, and consequently this fact warranted reporting...

..The patient did well without any recurrence of lesions, thus virtually excluding HAART as the cause of the bullous pemphigoid-like eruptions. Subsequently, he did not return for follow-up...

..With subsequent counseling, it was found that he continued to abuse pentazocine at times even after surgery leading to the non-healing of ulcers...

..Herein, we report an 11-year-old boy of childhood pemphigus vulgaris who failed to respond to dexamethasone pulse therapy and was subsequently treated with rituximab and achieved complete remission...

..Indian literature on AD is limited, probably due to lower prevalence, and milder disease. In this review, we have discussed the Indian literature on epidemiology and clinical features of AD...

..The epidemiology of the disease varies in different countries. In India, pemphigus is relatively common, with considerable interstate variation...

..Cutaneous vasculitis presents as a mosaic of clinical and histological findings. Its pathogenic mechanisms and clinical manifestations are varied...

..Owing to the rarity of the condition, the diagnosis is often a challenge; consequently, management is even more difficult owing to the paucity of experience and literature for the effective treatment of this entity...

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..Genetic linkage between different variants and the basis for their association is discussed...