W B Kannel

Summary

Publications

  1. ncbi request reprint Concept and usefulness of cardiovascular risk profiles
    William B Kannel
    National Heart, Lung, and Blood Institute s Framingham Study, National Institutes of Health, Boston University School of Medicine, Framingham, Mass 01702, USA
    Am Heart J 148:16-26. 2004
  2. ncbi request reprint Risk stratification of obesity as a coronary risk factor
    William B Kannel
    Framingham Study, Boston University School of Medicine, Framingham, Massachusetts, USA
    Am J Cardiol 90:697-701. 2002
  3. ncbi request reprint Assessment of cardiovascular risk and choice of antihypertensive therapy
    William B Kannel
    Boston University School of Medicine, 73 Mt Wayte Avenue, Suite 2, Framingham, MA 01702, USA
    Curr Hypertens Rep 6:346-51. 2004
  4. doi request reprint Angina pectoris is a stronger indicator of diffuse vascular atherosclerosis than intermittent claudication: Framingham study
    W B Kannel
    National Heart, Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    J Clin Epidemiol 61:951-7. 2008
  5. pmc Adverse consequences of the 50% misconception
    William B Kannel
    Framingham Heart Study, Framingham, MA, USA
    Am J Cardiol 103:426-7. 2009
  6. ncbi request reprint A likely explanation for the J-curve of blood pressure cardiovascular risk
    William B Kannel
    Boston University School of Medicine Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Am J Cardiol 94:380-4. 2004
  7. ncbi request reprint Lessons from curbing the coronary artery disease epidemic for confronting the impending epidemic of heart failure
    William B Kannel
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702 5827, USA
    Med Clin North Am 88:1129-33, ix. 2004
  8. pmc Triglycerides as vascular risk factors: new epidemiologic insights
    William B Kannel
    National Heart Lung and Blood Institute of the National Institutes of Health, USA
    Curr Opin Cardiol 24:345-50. 2009
  9. pmc Usefulness of the triglyceride-high-density lipoprotein versus the cholesterol-high-density lipoprotein ratio for predicting insulin resistance and cardiometabolic risk (from the Framingham Offspring Cohort)
    William B Kannel
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Am J Cardiol 101:497-501. 2008
  10. pmc Hypertension: reflections on risks and prognostication
    William B Kannel
    Boston University School of Medicine Framingham Heart Study, Framingham, MA 01702 5827, USA
    Med Clin North Am 93:541-58, Table of Contents. 2009

Detail Information

Publications81

  1. ncbi request reprint Concept and usefulness of cardiovascular risk profiles
    William B Kannel
    National Heart, Lung, and Blood Institute s Framingham Study, National Institutes of Health, Boston University School of Medicine, Framingham, Mass 01702, USA
    Am Heart J 148:16-26. 2004
    ..Multivariable risk stratification is now recognized as essential in efficiently identifying likely candidates for CVD and quantifying the hazard...
  2. ncbi request reprint Risk stratification of obesity as a coronary risk factor
    William B Kannel
    Framingham Study, Boston University School of Medicine, Framingham, Massachusetts, USA
    Am J Cardiol 90:697-701. 2002
    ..Global risk assessment can identify high-risk overweight candidates for CHD who most urgently need correction of associated risk factors, as well as sustained weight reduction...
  3. ncbi request reprint Assessment of cardiovascular risk and choice of antihypertensive therapy
    William B Kannel
    Boston University School of Medicine, 73 Mt Wayte Avenue, Suite 2, Framingham, MA 01702, USA
    Curr Hypertens Rep 6:346-51. 2004
    ..They require weight control and exercise, as well as specific choices of antihypertensive agents...
  4. doi request reprint Angina pectoris is a stronger indicator of diffuse vascular atherosclerosis than intermittent claudication: Framingham study
    W B Kannel
    National Heart, Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    J Clin Epidemiol 61:951-7. 2008
    ..To compare implications of Angina Pectoris (AP) and Intermittent Claudication (IC) as indicators of clinical atherosclerosis in other vascular territories...
  5. pmc Adverse consequences of the 50% misconception
    William B Kannel
    Framingham Heart Study, Framingham, MA, USA
    Am J Cardiol 103:426-7. 2009
    ..In conclusion, these data suggest that a more rigorous focus on these conventional risk factors and the lifestyle behaviors that promote them has great potential to reduce the burden of coronary artery disease worldwide...
  6. ncbi request reprint A likely explanation for the J-curve of blood pressure cardiovascular risk
    William B Kannel
    Boston University School of Medicine Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Am J Cardiol 94:380-4. 2004
    ..Patients with this condition of isolated systolic hypertension have been shown to benefit from antihypertensive treatment...
  7. ncbi request reprint Lessons from curbing the coronary artery disease epidemic for confronting the impending epidemic of heart failure
    William B Kannel
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702 5827, USA
    Med Clin North Am 88:1129-33, ix. 2004
    ....
  8. pmc Triglycerides as vascular risk factors: new epidemiologic insights
    William B Kannel
    National Heart Lung and Blood Institute of the National Institutes of Health, USA
    Curr Opin Cardiol 24:345-50. 2009
    ....
  9. pmc Usefulness of the triglyceride-high-density lipoprotein versus the cholesterol-high-density lipoprotein ratio for predicting insulin resistance and cardiometabolic risk (from the Framingham Offspring Cohort)
    William B Kannel
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Am J Cardiol 101:497-501. 2008
    ..In conclusion, our observations suggested that the TG/HDL cholesterol ratio was an imperfect surrogate for IR and its associated CHD risk, and it was only slightly better than the total/HDL cholesterol ratio for this purpose...
  10. pmc Hypertension: reflections on risks and prognostication
    William B Kannel
    Boston University School of Medicine Framingham Heart Study, Framingham, MA 01702 5827, USA
    Med Clin North Am 93:541-58, Table of Contents. 2009
    ....
  11. ncbi request reprint Long-term cardiovascular risk with protease inhibitors and management of the dyslipidemia
    William B Kannel
    Framingham Heart Study, Framingham, Massachusetts 01702 5728, USA
    Am J Cardiol 94:901-6. 2004
    ..Novel protease inhibitors, which have minimal effects on lipid profiles, may have a role in the long-term management of the human immunodeficiency virus...
  12. ncbi request reprint Cardiovascular disease preventive measures for the older patient: an epidemiologic perspective
    William B Kannel
    The Framingham Heart Study Boston University School of Medicine, 73 Mount Wayte Avenue, Framingham, MA 01702, USA
    Am J Geriatr Cardiol 15:382-8. 2006
  13. ncbi request reprint Aggressive lowering of blood pressure
    William B Kannel
    Boston University School of Medicine Framingham Heart Study, Framingham, MA 01702, USA
    Lancet 368:627-8. 2006
  14. pmc Current perceptions of the epidemiology of atrial fibrillation
    William B Kannel
    National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, MA 01702 5827, USA
    Cardiol Clin 27:13-24, vii. 2009
    ..The chief hazard of AF is embolic stroke, which is increased four- to fivefold, and in advanced age, it becomes a dominant stroke risk factor. AF also carries a doubled mortality rate...
  15. pmc Status of the epidemiology of atrial fibrillation
    William B Kannel
    Boston University, The Framingham Heart Study, 73 Mount Wayte Avenue, Framingham, MA 01702, USA
    Med Clin North Am 92:17-40, ix. 2008
    ..The chief hazard of AF is embolic stroke, which is increased four- to fivefold, assuming great importance in advanced age when it becomes a dominant factor. AF is associated with about a doubling of mortality...
  16. ncbi request reprint Risk stratification of dyslipidemia: insights from the Framingham Study
    W B Kannel
    Boston University School of Medicine Framingham Heart Study, MA 01702 5827, USA
    Curr Med Chem Cardiovasc Hematol Agents 3:187-93. 2005
    ..More attention needs to be afforded the absolute risk reduction attainable and must recognize that the number needed to treat to prevent one event increases the lower the lipid value, the lower global risk and the healthier the subject...
  17. ncbi request reprint Overview of hemostatic factors involved in atherosclerotic cardiovascular disease
    William B Kannel
    Boston University School of Medicine Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
    Lipids 40:1215-20. 2005
    ..It may be concluded that fibrinogen and CRP determination may be useful screening tools to identify individuals at added risk for thrombotic complications of CVD...
  18. ncbi request reprint Is the relation of systolic blood pressure to risk of cardiovascular disease continuous and graded, or are there critical values?
    William B Kannel
    National Heart, Lung, and Blood Institute s Framingham Study and the Department of Preventive Medicine, Boston University, Boston, Mass 01702 5827, USA
    Hypertension 42:453-6. 2003
  19. ncbi request reprint Impact of atrial fibrillation on the risk of death: the Framingham Heart Study
    E J Benjamin
    National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Mass, USA
    Circulation 98:946-52. 1998
    ..Atrial fibrillation (AF) causes substantial morbidity. It is uncertain whether AF is associated with excess mortality independent of associated cardiac conditions and risk factors...
  20. pmc Altered blood pressure progression in the community and its relation to clinical events
    Erik Ingelsson
    Framingham Heart Study, 73 Mount Wayte Ave, Ste 2, Framingham, MA 01702 5803, USA
    Arch Intern Med 168:1450-7. 2008
    ..Long-term blood pressure (BP) progression and its importance as a predictor of clinical outcome have not been well characterized across different periods...
  21. ncbi request reprint Impact of high-normal blood pressure on the risk of cardiovascular disease
    R S Vasan
    Framingham Heart Study, Mass 01702, USA
    N Engl J Med 345:1291-7. 2001
    ..Information is limited regarding the absolute and relative risk of cardiovascular disease in persons with high-normal blood pressure (systolic pressure of 130 to 139 mm Hg, diastolic pressure of 85 to 89 mm Hg, or both)...
  22. ncbi request reprint Coronary heart disease risk in people 65 years of age and older
    Barbara S Levine
    Department of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA, USA
    Prog Cardiovasc Nurs 18:135-40. 2003
    ..It is important to appreciate that the average remaining life expectancy after achieving 80 years is about 8 years...
  23. ncbi request reprint Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study
    R S Vasan
    From the National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA 01702, USA
    Lancet 358:1682-6. 2001
    ..We aimed to establish the best frequency of BP screening by assessing the rates and determinants of progression to hypertension...
  24. ncbi request reprint Clustering of metabolic factors and coronary heart disease
    P W Wilson
    National Heart, Lung, and Blood Institute, Framingham Heart Study, Mass 01701, USA
    Arch Intern Med 159:1104-9. 1999
    ..The degree of clustering for common metabolic coronary disease risk factors is not well known, the antecedents of clustering are not well studied, and the impact of such clusters on coronary risk has not been assessed systematically...
  25. ncbi request reprint Lifetime risk for developing congestive heart failure: the Framingham Heart Study
    Donald M Lloyd-Jones
    National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Framingham, MA 01702, USA
    Circulation 106:3068-72. 2002
    ..Congestive heart failure (CHF) is an increasing public health problem...
  26. ncbi request reprint Impact of atrial fibrillation on mortality, stroke, and medical costs
    P A Wolf
    Department of Neurology, Boston University, Mass, USA
    Arch Intern Med 158:229-34. 1998
    ..The impact of atrial fibrillation (AF) on mortality, stroke, and medical costs is unknown...
  27. ncbi request reprint Prediction of coronary heart disease using risk factor categories
    P W Wilson
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Mass 01701, USA
    Circulation 97:1837-47. 1998
    ....
  28. ncbi request reprint Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study
    Thomas J Wang
    Framingham Heart Study, 73 Mt Wayte Ave, Suite 2, Framingham, Mass 01702 5827, USA
    Circulation 107:2920-5. 2003
    ..Atrial fibrillation (AF) and congestive heart failure (CHF) frequently occur together, but there is limited information regarding their temporal relations and the combined influence of these conditions on mortality...
  29. ncbi request reprint Elevated midlife blood pressure increases stroke risk in elderly persons: the Framingham Study
    S Seshadri
    National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA
    Arch Intern Med 161:2343-50. 2001
    ..CONCLUSIONS: Antecedent BP contributes to the future risk of ischemic stroke. Optimal prevention of late-life stroke will likely require control of midlife BP...
  30. ncbi request reprint Relative importance of borderline and elevated levels of coronary heart disease risk factors
    Ramachandran S Vasan
    Framingham Heart Study, Framingham, Massachusetts 01702 5803, USA
    Ann Intern Med 142:393-402. 2005
    ..Clinical trials indicate that a sizable proportion of adults have multiple borderline coronary risk factors and may benefit from treatment...
  31. ncbi request reprint Intellectual decline after stroke: the Framingham Study
    C S Kase
    Department of Neurology, Boston University School of Medicine, Mass 02118, USA
    Stroke 29:805-12. 1998
    ..The causes and characteristics of cognitive decline after stroke are poorly defined, because most studies have relied on the diagnosis of dementia after stroke, without measurement of prestroke cognitive function...
  32. pmc Plasma leptin levels and incidence of heart failure, cardiovascular disease, and total mortality in elderly individuals
    Wolfgang Lieb
    Framingham Heart Study, Framingham, Massachusetts, USA
    Diabetes Care 32:612-6. 2009
    ..We tested the hypothesis that leptin levels are associated with greater risk of CHF, CVD, and mortality in elderly individuals...
  33. ncbi request reprint A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study
    Nisha I Parikh
    Framingham Heart Study, Framingham, Massachusetts 01702 5803, USA
    Ann Intern Med 148:102-10. 2008
    ..Risk stratification may facilitate cost-effective approaches to management...
  34. ncbi request reprint Risk stratification in hypertension: new insights from the Framingham Study
    W B Kannel
    Department of Epidemiology and Preventive Medicine, Medicine and Public Health, Boston University School of Medicine, Massachusetts 01702, USA
    Am J Hypertens 13:3S-10S. 2000
    ..Hypertensive patients are more appropriately targeted for therapy by such risk stratification and the goal of the therapy should be to improve the multivariate risk profile...
  35. ncbi request reprint Metabolic syndrome compared with type 2 diabetes mellitus as a risk factor for stroke: the Framingham Offspring Study
    Robert M Najarian
    Department of Neurology, Boston University School of Medicine, MA 02118 2526, USA
    Arch Intern Med 166:106-11. 2006
    ..Metabolic syndrome (MetS) has been recognized as a prediabetic constellation of symptoms and an independent risk factor for cardiovascular disease...
  36. ncbi request reprint Progression of uncontrolled hypertension and implications for managing its sequelae
    William B Kannel
    Boston University School of Medicine, USA
    Manag Care 12:26-33. 2003
    ..The predominant component of uncontrolled hypertension resides in systolic blood pressure...
  37. pmc Long-term trends in the incidence of heart failure after myocardial infarction
    Raghava S Velagaleti
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA 01702 5803, USA
    Circulation 118:2057-62. 2008
    ....
  38. ncbi request reprint Overweight and obesity as determinants of cardiovascular risk: the Framingham experience
    Peter W F Wilson
    Boston University School of Medicine, 715 Albany St, Evans 204, Boston, MA 02118, USA
    Arch Intern Med 162:1867-72. 2002
    ..To our knowledge, no single investigation concerning the long-term effects of overweight status on the risk for hypertension, hypercholesterolemia, diabetes mellitus, and cardiovascular sequelae has been reported...
  39. ncbi request reprint Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence
    Johan Sundstrom
    The Framingham Heart Study, Framingham, Mass 01702 5803, USA
    Hypertension 45:28-33. 2005
    ..02) and diastolic pressure 4 years later (P=0.04). In summary, serum UA level was an independent predictor of hypertension incidence and longitudinal BP progression at short-term follow-up in our community-based sample...
  40. ncbi request reprint Obesity and the risk of heart failure
    Satish Kenchaiah
    Framingham Heart Study, Framingham, Mass 01702, USA
    N Engl J Med 347:305-13. 2002
    ..Extreme obesity is recognized to be a risk factor for heart failure. It is unclear whether overweight and lesser degrees of obesity also pose a risk...
  41. doi request reprint General cardiovascular risk profile for use in primary care: the Framingham Heart Study
    RALPH B D'AGOSTINO
    Boston University, Department of Mathematics and Statistics, 111 Cummington St, Boston, MA 02215, USA
    Circulation 117:743-53. 2008
    ..The present report presents a single multivariable risk function that predicts risk of developing all CVD and of its constituents...
  42. ncbi request reprint Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study
    Ramachandran S Vasan
    Framingham Heart Study, 5 Thurber St, Framingham, MA 01702, USA
    JAMA 287:1003-10. 2002
    ..The long-term risk for developing hypertension is best described by the lifetime risk statistic. The lifetime risk for hypertension and trends in this risk over time are unknown...
  43. ncbi request reprint Epidemiologic appraisal of hypertension as a coronary risk factor in the elderly
    Christopher J O'Donnell
    National Heart, Lung, and Blood Institute s Framingham Heart Study, MA 01701, USA
    Am J Geriatr Cardiol 11:86-92. 2002
    ..The goal of therapy should be to improve the multivariate risk profile as well as the level of the blood pressure...
  44. ncbi request reprint Prevalence and implications of uncontrolled systolic hypertension
    William B Kannel
    National Heart, Lung and Blood Institutes Framingham Study and Boston University School of Medicine, Framingham, Massachusetts 01702 5827, USA
    Drugs Aging 20:277-86. 2003
    ..In such patients, ISH should be considered controlled when their global CVD risk is reduced to below the average for their age...
  45. ncbi request reprint Hypertensive risk assessment: cardiovascular risk factors and hypertension
    William B Kannel
    Framingham Heart Study, Framingham, MA 01702 5827, USA
    J Clin Hypertens (Greenwich) 6:393-9. 2004
  46. ncbi request reprint A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study
    Thomas J Wang
    Framingham Heart Study, Framingham, MA 01702 5827, USA
    JAMA 290:1049-56. 2003
    ....
  47. ncbi request reprint The Framingham Study: historical insight on the impact of cardiovascular risk factors in men versus women
    William B Kannel
    Department of Preventive Medicine and Epidemiology, Evans Department of Clinical Research, Boston University School of Medicine, Boston, MA, USA
    J Gend Specif Med 5:27-37. 2002
    ..There is a need for particular attention to glucose intolerance, abdominal obesity, and blood lipids, and a need for a great sense of urgency when hypertension is associated with diabetes or promotes left ventricular hypertrophy...
  48. ncbi request reprint Trends in incidence, lifetime risk, severity, and 30-day mortality of stroke over the past 50 years
    Raphael Carandang
    Department of Neurology, School of Medicine, Boston University, Boston, Mass 02118 2526, USA
    JAMA 296:2939-46. 2006
    ..Prior estimates of long-term trends in the incidence and severity of stroke have varied; trends in lifetime risk have not been reported...
  49. ncbi request reprint Peripheral and cerebral atherothrombosis and cardiovascular events in different vascular territories: insights from the Framingham Study
    William B Kannel
    Framingham Heart Study, 73 Mt Wayte Avenue, Framingham, MA 01702 5827, USA
    Curr Atheroscler Rep 8:317-23. 2006
    ....
  50. pmc Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study
    Rodrigo M Lago
    Framingham Heart Study, Framingham, Massachusetts 01702 5803, USA
    J Hypertens 26:2121-5. 2008
    ..Recent cross-sectional studies have suggested that higher serum sodium levels may be a marker of elevated blood pressure. It is unclear whether serum sodium levels are related to the risk of developing hypertension in the community...
  51. doi request reprint Beyond established and novel risk factors: lifestyle risk factors for cardiovascular disease
    Dariush Mozaffarian
    Division of Cardiovascular Medicine and Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Circulation 117:3031-8. 2008
  52. ncbi request reprint The lifetime risk of stroke: estimates from the Framingham Study
    Sudha Seshadri
    Department of Neurology, School of Medicine, Boston University, Boston, MA 02118 2526, USA
    Stroke 37:345-50. 2006
    ..The lifetime risk (LTR) of stroke has not been reported for the United States population; such data would assist public education and health planning...
  53. ncbi request reprint Temporal trends in the incidence of intermittent claudication from 1950 to 1999
    Joanne M Murabito
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702 5827, USA
    Am J Epidemiol 162:430-7. 2005
    ..IC incidence has declined since 1950, but mortality has remained high and unchanged. Factors contributing to the declining incidence of IC need clarification...
  54. ncbi request reprint Obesity, diabetes, and risk of cardiovascular disease in the elderly
    Peter W F Wilson
    Department of Medicine, Boston University Medical School, Boston, MA 02118, USA
    Am J Geriatr Cardiol 11:119-23,125. 2002
    ..Trial data indicate that preventive measures benefit obese diabetics even more than nondiabetics...
  55. ncbi request reprint Temporal trends in coronary heart disease mortality and sudden cardiac death from 1950 to 1999: the Framingham Heart Study
    Caroline S Fox
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA 01702, USA
    Circulation 110:522-7. 2004
    ..Although declines in coronary heart disease (CHD) mortality have been noted, there is still uncertainty about the magnitude of the decline and whether the trend is similar for sudden cardiac death (SCD)...
  56. pmc Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study
    Renate B Schnabel
    Framingham Heart Study, Framingham, MA, USA Department of Medicine II, Johannes Gutenberg University, Mainz, Germany
    Lancet 373:739-45. 2009
    ..We aimed to develop a risk score to predict individuals' absolute risk of developing the condition, and to provide a framework for researchers to assess new risk markers...
  57. doi request reprint Prediction of intermittent claudication, ischemic stroke, and other cardiovascular disease by detection of abdominal aortic calcific deposits by plain lumbar radiographs
    Yamini S Levitzky
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Am J Cardiol 101:326-31. 2008
    ..AAC appears to be useful for risk stratification in patients at intermediate CHD risk...
  58. pmc Genetics of the Framingham Heart Study population
    Diddahally R Govindaraju
    Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Adv Genet 62:33-65. 2008
    ..Finally, the use of this unique sample to study genotype and environment interactions is described...
  59. ncbi request reprint Plasma renin and risk of cardiovascular disease and mortality: the Framingham Heart Study
    Nisha I Parikh
    Framingham Heart Study, Boston University School of Medicine, 73 Mount Wayte Avenue, Suite 2, Framingham, MA 01702 5803, USA
    Eur Heart J 28:2644-52. 2007
    ..We related plasma renin to incidence of CVD and mortality in 3408 individuals (mean age 59; 53% women) and in a hypertensive subset (n = 1413)...
  60. ncbi request reprint Prospects for prevention of coronary disease in the elderly. Introduction
    William B Kannel
    Boston University School of Medicine, MA, USA
    Am J Geriatr Cardiol 11:83-4. 2002
  61. ncbi request reprint Coronary heart disease risk factors in the elderly
    William B Kannel
    Department of Preventive Medicine and Epidemiology, Evans Department of Clinical Research, Boston University School of Medicine, Boston, MA, USA
    Am J Geriatr Cardiol 11:101-7. 2002
    ..Trials of risk factor modification in the elderly indicate that decades of exposure to modifiable risk factors can be countered by measures implemented late in life...
  62. ncbi request reprint Electrocardiographic QRS duration and the risk of congestive heart failure: the Framingham Heart Study
    Ravi Dhingra
    Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA, USA
    Hypertension 47:861-7. 2006
    ..In our community-based sample, longer electrocardiographic QRS was associated with increased CHF risk, consistent with the hypothesis that depolarization delay may increase CHF risk...
  63. ncbi request reprint Menopause, hormones, and cardiovascular vulnerability in women
    William B Kannel
    Framingham Heart Study, MA 01702, USA
    Arch Intern Med 164:479-81. 2004
  64. ncbi request reprint Cardioprotection: what is it? Who needs it?
    William B Kannel
    Department of Preventive Medicine and Epidemiology, Boston University School of Medicine, USA
    Am J Manag Care 8:5-12. 2002
  65. pmc Relations of lipid concentrations to heart failure incidence: the Framingham Heart Study
    Raghava S Velagaleti
    Framingham Heart Study, Center for Population Studies, National Heart, Lung, and Blood Institute, 73 Mt Wayte Avenue, Framingham, MA 01702, USA
    Circulation 120:2345-51. 2009
    ..The relations of lipid concentrations to heart failure (HF) risk have not been elucidated comprehensively...
  66. ncbi request reprint A comparison of death certificate out-of-hospital coronary heart disease death with physician-adjudicated sudden cardiac death
    Caroline S Fox
    National Heart, Lung and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Am J Cardiol 95:856-9. 2005
    ..Out-of-hospital coronary heart disease deaths overestimated sudden cardiac death by 47%, suggesting that out-of-hospital coronary heart disease death rates derived from death certificates should be interpreted with caution...
  67. ncbi request reprint Age-specific relevance of usual blood pressure to vascular mortality
    Stanley S Franklin
    Lancet 361:1389; author reply 1391-2. 2003
  68. ncbi request reprint [Coronary risk estimation in Spain using a calibrated Framingham function]
    Jaume Marrugat
    Unitat de Lípids i Epidemiologia Cardiovascular Institut Municipal d Investigació Mèdica IMIM Barcelona Universitat Autònoma de Barcelona Spain
    Rev Esp Cardiol 56:253-61. 2003
    ..Color-coded charts were prepared that show the exact probability of CHD corresponding to each combination of risk factors, shown in separate cells on the chart...
  69. ncbi request reprint Are guidelines effectively guiding antihypertensive therapy?
    Ramachandran S Vasan
    Am J Cardiol 100:143-4. 2007
  70. ncbi request reprint Cardiovascular hazards of components of blood pressure
    William B Kannel
    J Hypertens 20:395-7. 2002
  71. ncbi request reprint How important is pulse pressure as a predictor of cardiovascular risk?
    Stanley S Franklin
    Hypertension 39:E12-3. 2002
  72. ncbi request reprint Recent US and European blood pressure guidelines: implications for developing countries
    Ramachandran S Vasan
    Natl Med J India 16:241-4. 2003
  73. ncbi request reprint Search for an optimal atherogenic lipid risk profile: from the Framingham Study
    Byung Ho Nam
    National Cancer Institute, Research Institute for National Cancer Control and Evaluation, Gyeonggildo, Korea
    Am J Cardiol 97:372-5. 2006
    ..In women, the ratio is also a good CHD predictor, but a combination of a high ratio accompanied by high LDL cholesterol may warrant more aggressive therapy...
  74. ncbi request reprint Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study
    Jing Liu
    Department of Epidemiology, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China
    JAMA 291:2591-9. 2004
    ..Recalibration of Framingham functions could permit various regions of the world to adapt Framingham tools to local populations...
  75. ncbi request reprint Pulse pressure and risk of new-onset atrial fibrillation
    Gary F Mitchell
    Cardiovascular Engineering Inc, Waltham, Mass 02453, USA
    JAMA 297:709-15. 2007
    ..Increased pulse pressure, a reflection of aortic stiffness, increases cardiac load and may increase AF risk...
  76. ncbi request reprint Antecedent blood pressure, body mass index, and the risk of incident heart failure in later life
    Douglas S Lee
    Institute for Clinical Evaluative Sciences and University Health Network, University of Toronto, Toronto, Canada
    Hypertension 50:869-76. 2007
    ..Higher blood pressure and BMI in midlife are harbingers of increased risk of heart failure in later life. Early risk factor modification may decrease heart failure burden...
  77. ncbi request reprint Postoperative atrial fibrillation and mortality: do the risks merit changes in clinical practice?
    Daniel Levy
    J Am Coll Cardiol 43:749-51. 2004
  78. ncbi request reprint Glaucoma risk factor assessment and prevention: lessons from coronary heart disease
    Christopher A Girkin
    Callahan Eye Foundation Hospital, University of Alabama at Birmingham, Birmingham, Alabama 35249 0009, USA
    Am J Ophthalmol 138:S11-8. 2004
    ..To determine whether multivariable risk factor assessment can be as successful in developing disease prevention strategies in patients with ocular hypertension as it has been in patients at risk for coronary heart disease (CHD)...
  79. ncbi request reprint Hormone therapy and cardiovascular disease
    William B Kannel
    N Engl J Med 349:2075-6; author reply 2075-6. 2003
  80. ncbi request reprint Avoiding the looming Latino/Hispanic cardiovascular health crisis: a call to action
    Jaime A Davidson
    University of Texas Southwestern Medical School, Dallas, TX, USA
    J Cardiometab Syndr 2:238-43. 2007
    ..A combined effort of health-influencing and health-governing bodies is needed on all levels to address the CVD problem in the Latino/Hispanic population...
  81. ncbi request reprint Cardiovascular disease prevention and care in Latino and Hispanic subjects
    Jaime A Davidson
    University of Texas Southwestern Medical School, Dallas, Texas, USA
    Endocr Pract 13:77-85. 2007
    ..To determine the scope, impact, and health care limitations relative to cardiovascular disease (CVD) in the Latino-Hispanic population...