Jennifer A Johnston

Summary

Publications

  1. ncbi request reprint Cytoplasmic dynein/dynactin mediates the assembly of aggresomes
    Jennifer A Johnston
    Department of Biological Sciences, Stanford University, Stanford, California, USA
    Cell Motil Cytoskeleton 53:26-38. 2002
  2. ncbi request reprint HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
    Atsushi Iwata
    Department of Biological Sciences, Bio X Program, Stanford University, Stanford, California 94305 5430, USA
    J Biol Chem 280:40282-92. 2005
  3. ncbi request reprint Cellular mechanisms of protein quality control
    Eric J Bennett
    Department of Biological Sciences, Stanford University, USA
    Rinsho Shinkeigaku 46:805. 2006
  4. ncbi request reprint Direct interaction of soluble human recombinant tau protein with Abeta 1-42 results in tau aggregation and hyperphosphorylation by tau protein kinase II
    Kenneth B Rank
    Protein Science, 7240 267 117, Pharmacia Corporation, Kalamazoo, MI 49007, USA
    FEBS Lett 514:263-8. 2002
  5. ncbi request reprint Rings, chains and ladders: ubiquitin goes to work in the neuron
    Jennifer A Johnston
    Elan Pharmaceuticals, 1000 Gateway Blvd, South San Francisco, CA 9408, USA
    Prog Neurobiol 73:227-57. 2004

Collaborators

  • Brigit E Riley
  • Atsushi Iwata
  • Eric J Bennett
  • Ron R Kopito
  • Kenneth B Rank
  • Lisa Ellerby
  • Noboyuki Nukina
  • Mirella Gonzalez-Zulueta
  • Tom Shaler
  • Mirella Bucci
  • Howard F Schulman
  • Keshab Bhattacharya
  • Adele M Pauley
  • Timothy J Fleck
  • David B Evans
  • Satish K Sharma
  • Zhigang Wang

Detail Information

Publications5

  1. ncbi request reprint Cytoplasmic dynein/dynactin mediates the assembly of aggresomes
    Jennifer A Johnston
    Department of Biological Sciences, Stanford University, Stanford, California, USA
    Cell Motil Cytoskeleton 53:26-38. 2002
    ..We conclude that cytoplasmic dynein/dynactin is responsible for the directed transport of misfolded protein into aggresomes. The implications of these findings with respect to the pathogenesis of neurodegenerative disease are discussed...
  2. ncbi request reprint HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
    Atsushi Iwata
    Department of Biological Sciences, Bio X Program, Stanford University, Stanford, California 94305 5430, USA
    J Biol Chem 280:40282-92. 2005
    ..These data suggest that HDAC6-dependent retrograde transport on microtubules is used by cells to increase the efficiency and selectivity of autophagic degradation...
  3. ncbi request reprint Cellular mechanisms of protein quality control
    Eric J Bennett
    Department of Biological Sciences, Stanford University, USA
    Rinsho Shinkeigaku 46:805. 2006
  4. ncbi request reprint Direct interaction of soluble human recombinant tau protein with Abeta 1-42 results in tau aggregation and hyperphosphorylation by tau protein kinase II
    Kenneth B Rank
    Protein Science, 7240 267 117, Pharmacia Corporation, Kalamazoo, MI 49007, USA
    FEBS Lett 514:263-8. 2002
    ..Taken together, these in vitro results suggest that Abeta 1-42 promotes both tau aggregation and hyperphosphorylation...
  5. ncbi request reprint Rings, chains and ladders: ubiquitin goes to work in the neuron
    Jennifer A Johnston
    Elan Pharmaceuticals, 1000 Gateway Blvd, South San Francisco, CA 9408, USA
    Prog Neurobiol 73:227-57. 2004
    ..Our goal is to excite the expert neurobiologist to the myriad ways that specific neuronal functions could be regulated (or dysregulated) by mechanisms involving the Ub/proteasome pathway...