A genome-wide linkage study of mammographic density, a risk factor for breast cancerCelia M T Greenwood
Program in Genetics and Genome Biology, The Hospital for Sick Children, 101 College Street, East Tower, Toronto, ON M5G 1L7, Canada
Breast Cancer Res 13:R132. 2011
..Mammographic breast density is a highly heritable (h2 > 0.6) and strong risk factor for breast cancer. We conducted a genome-wide linkage study to identify loci influencing mammographic breast density (MD)...
- Rare variants in the ATM gene and risk of breast cancer
David E Goldgar
Department of Dermatology, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132 2101, USA
Breast Cancer Res 13:R73. 2011
..However, the magnitude of risk and the subset of variants that are pathogenic for breast cancer remain unresolved...
- Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry
Letitia D Smith
Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Melbourne, Victoria 3010, Australia
Breast Cancer Res 13:R14. 2011
..We sought to test the value of selecting women for BRCA1 mutation testing on the basis of family history and/or breast tumour morphology criteria as well as the value of testing for large genomic alterations in BRCA1...
- Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study
Florence Le Calvez-Kelm
International Agency for Research on Cancer, 150 cours Albert Thomas, Lyon Cedex 08, F 69372, France
Breast Cancer Res 13:R6. 2011
..This absence has been due in part to a lack of validated statistical methods for summarizing risk attributable to large numbers of individually rare missense substitutions...
- Meat consumption, cooking practices, meat mutagens, and risk of prostate cancer
Esther M John
Cancer Prevention Institute of California, Fremont, California 94538, USA
Nutr Cancer 63:525-37. 2011
..These findings provide further evidence that consumption of processed meat and red meat cooked at high temperature is associated with increased risk of advanced, but not localized, prostate cancer...
- Adult body size, hormone receptor status, and premenopausal breast cancer risk in a multiethnic population: the San Francisco Bay Area breast cancer study
Esther M John
Cancer Prevention Institute of California, Fremont, 94538, USA
Am J Epidemiol 173:201-16. 2011
..Despite racial/ethnic differences in body size, inverse associations were similar across the 3 racial/ethnic groups when stratified by hormone receptor status...
- Lifetime physical activity and risk of endometrial cancer
Esther M John
Cancer Prevention Institute of California, 2201 Walnut Avenue, Suite 300, Fremont, CA 94538, USA
Cancer Epidemiol Biomarkers Prev 19:1276-83. 2010
..The role of moderate physical activity and life patterns of activity in reducing endometrial cancer risk remains uncertain...
- Early-life factors and breast cancer risk in Hispanic women: the role of adolescent body size
Meera Sangaramoorthy
Cancer Prevention Institute of California, Fremont, CA 94538, USA
Cancer Epidemiol Biomarkers Prev 20:2572-82. 2011
..Adult body size has long been known to influence breast cancer risk, and there is now increasing evidence that childhood and adolescent body size may also play a role...
- Recent changes in breast cancer incidence and risk factor prevalence in San Francisco Bay area and California women: 1988 to 2004
Theresa H M Keegan
Northern California Cancer Center, 2201 Walnut Ave, Suite 300, Fremont, CA 94538, USA
Breast Cancer Res 9:R62. 2007
..In light of these reports, we examined recent changes in breast cancer incidence and risk factor prevalence among non-Hispanic white women in the SFBA and other regions of California...
Migration history, acculturation, and breast cancer risk in Hispanic womenEsther M John
Northern California Cancer Center, Suite 300, 2201 Walnut Avenue, Fremont, CA 94538, USA
Cancer Epidemiol Biomarkers Prev 14:2905-13. 2005
..We examined the influence of migration history and acculturation on breast cancer risk in Hispanic women ages 35 to 79 years...
- Medical radiation exposure and breast cancer risk: findings from the Breast Cancer Family Registry
Esther M John
Northern California Cancer Center, Fremont, CA 94538, USA
Int J Cancer 121:386-94. 2007
..Given the widespread and increasing use of medical diagnostic radiation, continued surveillance of breast cancer risk is warranted, particularly in women at specific genetic risk, such as those carrying mutations in BRCA1 or BRCA2...
- Sun exposure, vitamin D receptor gene polymorphisms, and breast cancer risk in a multiethnic population
Esther M John
Northern California Cancer Center, Fremont, CA 94538, USA
Am J Epidemiol 166:1409-19. 2007
..Localized breast cancer was not associated with sun exposure or VDR genotype. This study supports the hypothesis that sunlight exposure reduces risk of advanced breast cancer among women with light skin pigmentation...
- Family history of breast cancer and all-cause mortality after breast cancer diagnosis in the Breast Cancer Family Registry
Ellen T Chang
Northern California Cancer Center, Fremont, 94538, USA
Breast Cancer Res Treat 117:167-76. 2009
..Therefore, clinical management should not depend on family history of breast cancer...
- Second primary breast cancer occurrence according to hormone receptor status
Allison W Kurian
Northern California Cancer Center, 2201 Walnut Ave, Fremont, CA 94538 2334, USA
J Natl Cancer Inst 101:1058-65. 2009
..Little is known about differences in risk for second primary breast cancers related to the estrogen and progesterone receptor (hormone receptor [HR]) status of the first tumor...
- Breast cancer incidence patterns among California Hispanic women: differences by nativity and residence in an enclave
Theresa H M Keegan
Northern California Cancer Center, 2201 Walnut Avenue, Suite 300, Fremont, CA 94538, USA
Cancer Epidemiol Biomarkers Prev 19:1208-18. 2010
....
- Past recreational physical activity, body size, and all-cause mortality following breast cancer diagnosis: results from the Breast Cancer Family Registry
Theresa H M Keegan
Northern California Cancer Center, 2201 Walnut Ave, Suite 300, Fremont, CA 94536, USA
Breast Cancer Res Treat 123:531-42. 2010
..90-2.15; HR for obese = 1.77, 95% CI: 1.11-2.82). BMI associations did not appear to differ by race/ethnicity. Our findings suggest that physical activity and BMI exert independent effects on overall mortality after breast cancer...
- Sun exposure, vitamin D receptor gene polymorphisms, and risk of advanced prostate cancer
Esther M John
Northern California Cancer Center, Fremont, California 94538, USA
Cancer Res 65:5470-9. 2005
..46 to 0.67. Our findings support the hypothesis that sun exposure and VDR polymorphisms together play important roles in the etiology of prostate cancer...
