Xiaobin Jia

Summary

Publications

  1. ncbi request reprint [Progress in research of processing of fructus Evodiae-Rhizoma Coptidis and research thoughts and methods of its processing mechanism]
    Xiaobin Jia
    School of Pharmacy, Jiangsu University, Zhen Jiang 212013, China
    Zhongguo Zhong Yao Za Zhi 34:1314-7. 2009
  2. ncbi request reprint [Optimization of extraction procedure of tongmai granules by orthogonal design with pharmacodynamic index]
    Xiaobin Jia
    School of Pharmacy, Jiangsu University, Zhenjiang 212013, China
    Zhongguo Zhong Yao Za Zhi 36:154-7. 2011
  3. doi request reprint Formulation and evaluation of celastrol-loaded liposomes
    Jie Song
    Key Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, Jiangsu, China
    Molecules 16:7880-92. 2011
  4. ncbi request reprint [Ideas and methods of fresh herb basic research based on constituent structure theory]
    Xiaobin Jia
    School of Pharmacy, Jiangsu University, Zhenjiang 212013, China
    Zhongguo Zhong Yao Za Zhi 36:2595-8. 2011
  5. ncbi request reprint [Simultaneously determination of atropine sulphate, diphenhydramine hydrochloride, capsaicin and dihydrocapsaicin in pain-relieving plaster for arthritis by RP-HPLC]
    Xiaobin Jia
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 35:2838-41. 2010
  6. ncbi request reprint [Study on preparation of CIT microemulsion and its absorption in intestine]
    Xiaobin Jia
    Department of Pharmaceutics, Jiangsu University, Zhenjiang 212013, China
    Zhongguo Zhong Yao Za Zhi 35:435-8. 2010
  7. ncbi request reprint [Research on variation regularity of five main flavonoids contents in Epimedium and processed Epimedium]
    Xiaoyong Jin
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Key Unit of Chinese Medicine Drug Delivery System of State Administration of Traditional Chinese Medicine, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 34:2738-42. 2009
  8. ncbi request reprint [Multi-channel analysis and comparison on absorption difference between paeoniflorin and Paeonia lactiflora extracts]
    Yan Chen
    Key Laboratory of Chinese Medicine New Drug Delivery Systems, Jiangsu Institute of Traditional Chinese Medicine, Key Laboratory of Chinese Medicine Oral Formulations Drug Delivery Systems, State Administration of Traditional Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 37:2012-6. 2012
  9. doi request reprint The protection of 4,4'-diphenylmethane-bis(methyl) carbamate from Cortex Mori on advanced glycation end product-induced endothelial dysfunction: via inhibiting AGE formation or blocking AGEs-RAGE axis?
    Liang Feng
    Key Laboratory of New Drug Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing 210028, China
    Fitoterapia 89:239-49. 2013
  10. doi request reprint Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer
    Jie Song
    Key Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing 210028, China
    Chem Biol Interact 199:9-17. 2012

Collaborators

Detail Information

Publications40

  1. ncbi request reprint [Progress in research of processing of fructus Evodiae-Rhizoma Coptidis and research thoughts and methods of its processing mechanism]
    Xiaobin Jia
    School of Pharmacy, Jiangsu University, Zhen Jiang 212013, China
    Zhongguo Zhong Yao Za Zhi 34:1314-7. 2009
    ....
  2. ncbi request reprint [Optimization of extraction procedure of tongmai granules by orthogonal design with pharmacodynamic index]
    Xiaobin Jia
    School of Pharmacy, Jiangsu University, Zhenjiang 212013, China
    Zhongguo Zhong Yao Za Zhi 36:154-7. 2011
    ..To optimize the extraction technology for anti-myocardial ischemia active component group in tongmai granules...
  3. doi request reprint Formulation and evaluation of celastrol-loaded liposomes
    Jie Song
    Key Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, Jiangsu, China
    Molecules 16:7880-92. 2011
    ..05). Moreover, celastrol-loaded liposomes could also inhibit the tumor growth in C57BL/6 mice. These results suggest that liposomes could be a promising perioral carrier for celastrol...
  4. ncbi request reprint [Ideas and methods of fresh herb basic research based on constituent structure theory]
    Xiaobin Jia
    School of Pharmacy, Jiangsu University, Zhenjiang 212013, China
    Zhongguo Zhong Yao Za Zhi 36:2595-8. 2011
    ..It was an effectual method for studying on the reasonable development of Chinese medicine and fresh herbs resources...
  5. ncbi request reprint [Simultaneously determination of atropine sulphate, diphenhydramine hydrochloride, capsaicin and dihydrocapsaicin in pain-relieving plaster for arthritis by RP-HPLC]
    Xiaobin Jia
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 35:2838-41. 2010
    ..To establish RP-HPLC method for determination of atropine sulphate, diphenhydramine hydrochloride, capsaicin and dihydrocapsaicin in pain-relieving plaster for arthritis...
  6. ncbi request reprint [Study on preparation of CIT microemulsion and its absorption in intestine]
    Xiaobin Jia
    Department of Pharmaceutics, Jiangsu University, Zhenjiang 212013, China
    Zhongguo Zhong Yao Za Zhi 35:435-8. 2010
    ..To prepare CIT microemulsion and to investigate its properities and the absorption character in rat intestine in situ...
  7. ncbi request reprint [Research on variation regularity of five main flavonoids contents in Epimedium and processed Epimedium]
    Xiaoyong Jin
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Key Unit of Chinese Medicine Drug Delivery System of State Administration of Traditional Chinese Medicine, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 34:2738-42. 2009
    ..To research on the variation regularity of the five main flavonoids contents in Epimedium and processed Epimedium...
  8. ncbi request reprint [Multi-channel analysis and comparison on absorption difference between paeoniflorin and Paeonia lactiflora extracts]
    Yan Chen
    Key Laboratory of Chinese Medicine New Drug Delivery Systems, Jiangsu Institute of Traditional Chinese Medicine, Key Laboratory of Chinese Medicine Oral Formulations Drug Delivery Systems, State Administration of Traditional Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 37:2012-6. 2012
    ..To compare the difference of the absorption difference between paeoniflorin monomer and Paeonia lactiflora extracts in rat intestinal canals by multi-channels...
  9. doi request reprint The protection of 4,4'-diphenylmethane-bis(methyl) carbamate from Cortex Mori on advanced glycation end product-induced endothelial dysfunction: via inhibiting AGE formation or blocking AGEs-RAGE axis?
    Liang Feng
    Key Laboratory of New Drug Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing 210028, China
    Fitoterapia 89:239-49. 2013
    ..Our results suggested that CM1 might block the AGEs-RAGE signal transduction rather than inhibit AGE formation or bind to AGEs and change its structure to prevent endothelial dysfunction in diabetic vascular complications. ..
  10. doi request reprint Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer
    Jie Song
    Key Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing 210028, China
    Chem Biol Interact 199:9-17. 2012
    ..These findings suggested that Baohuoside I might exert its cytotoxic effect via the ROS/MAPK pathway...
  11. doi request reprint Metabolite profiles of epimedin B in rats by ultraperformance liquid chromatography/quadrupole-time-of-flight mass spectrometry
    Li Cui
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, Jiangsu Province, China
    J Agric Food Chem 61:3589-99. 2013
    ..This study revealed the possible metabolite profiles of epimedin B in rats...
  12. doi request reprint Ursolic acid inhibits cigarette smoke extract-induced human bronchial epithelial cell injury and prevents development of lung cancer
    Wenbo Liu
    Key Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, Jiangsu 210028, China
    Molecules 17:9104-15. 2012
    ..Moreover, UA inhibited lung cancer development in the model established by A549 cells in nude mice in vivo. For the first time, our results indicate that UA could be developed as a potential lung cancer chemopreventive agent...
  13. ncbi request reprint [Absorption and metabolism of flavonoids in Herba Epimedii via rat intestinal perfusion model]
    Yan Chen
    Jiangsu Provincial Academy of Traditional Chinese Medicine, Jiangsu Engineering and Technology Research Center for Modern Chinese Pharmaceutical Preparation, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 34:2928-31. 2009
    ..To study the absorption and metabolism of five flavonoids of Herba Epimedii (icariin, epimedin A, epi-medin B, epimedin C and baohuoside I) in rat intestine...
  14. doi request reprint Interaction of the main components from the traditional Chinese drug pair Chaihu-Shaoyao based on rat intestinal absorption
    Yan Chen
    Key Laboratory of New Drug Delivery System of Chinese Material Medica, Jiangsu Province, Academy of Chinese Medicine, 100 Shizi Road, Nanjing 210028, China
    Molecules 16:9600-10. 2011
    ..In conclusion, SSA and SSD could promote the absorption of paeoniflorin. To some extent this might explain the nature of the compatibility mechanisms of composite formulae in TCMs...
  15. doi request reprint Role of intestinal hydrolase in the absorption of prenylated flavonoids present in Yinyanghuo
    Yan Chen
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, 100 Shizi Road, Nanjing 210028, China
    Molecules 16:1336-48. 2011
    ..The aim of this study was to examine the significance of the intestinal hydrolysis of prenylated flavonoids by lactase phlorizin hydrolase (LPH), an enzyme at the brush border membrane of intestinal cells...
  16. doi request reprint Metabolism of tanshinone IIA, cryptotanshinone and tanshinone I from Radix Salvia miltiorrhiza in zebrafish
    Yingjie Wei
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, 100 Shizi Street, Nanjing 210028, China
    Molecules 17:8617-32. 2012
    ....
  17. ncbi request reprint [Preparation of Ganoderma lucidum polysaccharides and triterpenes microemulsion and its anticancer effect in mice with transplant Heps tumors]
    Yan Chen
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Key Laboratory of Scientific Preparation for Clinical Effective Prescription of State Administration of Traditional Chinese Medicine, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 35:2679-83. 2010
    ..To research the microemulsion preparation of Ganoderma lucidum polysaccharides and triterpenes and investigate its properities. Evaluate the effects of polysaccharides and triterpenes microemulsions against transplant tumor growth...
  18. ncbi request reprint [Preparation and transdermal diffusion of ursolic acid ethosomes]
    Yan Chen
    Department of Pharmaceutics, Jiangsu University, Zhenjiang 212013, China
    Zhongguo Zhong Yao Za Zhi 36:988-91. 2011
    ..To prepare ursolic acid ethosomes and investigate the penetration characteristics of ursolic ethosomes as a transdermal vehicle...
  19. ncbi request reprint [Study on preparation of icaritin by enzymolysis of icariin with snail hydrolase]
    Dongsheng Jia
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 35:857-60. 2010
    ..To optimize the conditions for enzymolysis of Icariin by snail hydrolase...
  20. doi request reprint Revolving door action of breast cancer resistance protein (BCRP) facilitates or controls the efflux of flavone glucuronides from UGT1A9-overexpressing HeLa cells
    Yingjie Wei
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, 100 Shizi Street, Nanjing 210028, China
    Mol Pharm 10:1736-50. 2013
    ....
  21. ncbi request reprint [Preparation of naringenin by enzymolysis of naringin-HP-beta-CD]
    Li Cui
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 37:310-4. 2012
    ....
  22. doi request reprint Metabolite profiling of four major flavonoids of Herba Epimedii in zebrafish
    Yingjie Wei
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, 100 Shizi Street, Nanjing 210028, China
    Molecules 17:420-32. 2012
    ..This novel model can also be applied in quickly predicting the metabolism of Chinese herb components, especially trace compounds...
  23. ncbi request reprint [Intestinal absorption properties of flavones and extract of fructus aurantii immaturus in rats]
    Ran Xin
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 35:1850-4. 2010
    ..To investigate the intestinal absorption of naringin, hesperidin, neohesperidin and the extract of Fructus Aurantii Immaturus in rats...
  24. ncbi request reprint Chemoprevention by Prunella vulgaris L. extract of non-small cell lung cancer via promoting apoptosis and regulating the cell cycle
    Liang Feng
    Key Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
    Asian Pac J Cancer Prev 11:1355-8. 2010
    ..In addition, P-60 was found to have the ability to regulate cell cycle and induce apoptosis in SPC-A-1 cells. Therefore, we propose that P-60 has potential as a lung cancer chemopreventive agent...
  25. ncbi request reprint [Correlation of powder properties and formability of traditional Chinese medicine pellets]
    Yang Huang
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 35:3136-9. 2010
    ..To investigate the correlation of powder properties and formability of traditional Chinese medicine pellets prepared by extrusion/spheronization...
  26. doi request reprint Antioxidant activities of total phenols of Prunella vulgaris L. in vitro and in tumor-bearing mice
    Liang Feng
    Biotechnology Laboratory of Chinese Medicine, Macau University of Science and Technology, Macau, China
    Molecules 15:9145-56. 2010
    ..These results suggested that P-60 extract had high antioxidant activity in vitro and in vivo and total phenols played an important role in antioxidant activity for inhibition of tumor growth...
  27. doi request reprint Amelioration of compound 4,4'-diphenylmethane-bis(methyl)carbamate on high mobility group box1-mediated inflammation and oxidant stress responses in human umbilical vein endothelial cells via RAGE/ERK1/2/NF-κB pathway
    Liang Feng
    Key Laboratory of Delivery Systems of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, 210028, China
    Int Immunopharmacol 15:206-16. 2013
    ..Our findings indicated that CM1 attenuated HMGB1-mediated endothelial activation by ameliorating inflammation and oxidant stress responses via RAGE/ERK1/2/NF-κB pathway...
  28. pmc Effect of β-cyclodextrin complexation on solubility and enzymatic hydrolysis rate of icariin
    Li Cui
    Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, China
    J Nat Sci Biol Med 4:201-6. 2013
    ..The aim of this work was to investigate the effect of β-cyclodextrin complexation on the solubility and hydrolysis rate of icariin...
  29. ncbi request reprint [Thought and application of traditional Chinese medicine multiple drug delivery system based on material basis component]
    E Sun
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 37:2181-5. 2012
    ..This new research model of Chinese drugs pharmaceutics provides new strategies and methods for the development of modern Chinese drug delivery systems...
  30. doi request reprint Anti-hepatitis B virus activity of chickweed [Stellaria media (L.) Vill.] extracts in HepG2.2.15 cells
    Lihua Ma
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, 100 Shizi Street, Nanjing 210028, China
    Molecules 17:8633-46. 2012
    ..This is the first report demonstrating the anti-HBV effects of S. media, which is currently under early development as a potential anti-HBV drug candidate...
  31. doi request reprint Antioxidant activities of various extracts from Artemisisa selengensis Turcz (LuHao)
    Feng Shi
    Key Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, 210028, China
    Molecules 15:4934-46. 2010
    ..In summary, we propose that AST could be potentially used as a rich source of natural antioxidants...
  32. ncbi request reprint [Market investigation report on Epimedium material drugs and decoction pieces]
    BaoLin Guo
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
    Zhongguo Zhong Yao Za Zhi 35:1687-90. 2010
    ....
  33. pmc Simultaneous determination of 5 phenolic acids in fried Fructus xanthii from different production sites and its dispensing granules by using ultra-pressure liquid chromatography
    Bin Chen
    Department of Pharmacy, Key Laboratory of Chinese Medicine Delivery System of State Administration of Traditional Chinese Medicine, Jiangsu Provincial Academy of Chinese Medicine, China
    Pharmacogn Mag 9:103-8. 2013
    ....
  34. ncbi request reprint [Construction of multiple drug release system based on components of traditional Chinese medicine]
    Dan Liu
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 37:2338-43. 2012
    ....
  35. ncbi request reprint [Study on solid dispersion of binary vector of tanshinone II A]
    Yanrong Jiang
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 37:1383-7. 2012
    ..To prepare the solid dispersion of tanshinone II A (TS II A) by the combined application of nano-silica and poloxamer 188 (F68), in order to observe its dissolution and stability...
  36. ncbi request reprint [Conditions for extraction of ergosterol from fruits of Ganoderma lucidum using supercritical fluid extration]
    Shihua Song
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 34:1783-5. 2009
    ..To study the feasibility of supercritical fluid extraction (SFE) for extraction of ergosterols from the fruits of Ganoderma lucidum...
  37. ncbi request reprint [Comparison of content of clemastanin B of Radix Isatidis in different growing areas]
    Yiqiang An
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Key Laboratory of Scientfic Preparation for Clinical Effective Prescription of State Administration of Traditional Chinese Medicine, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 34:1823-5. 2009
    ..To develop an HPLC method for determination of clemastanin B which has anti-viral activity in Radix Isatidis and compare the contents of clemastanin B in the drugs from different origins...
  38. doi request reprint The pharmacokinetics of raloxifene and its interaction with apigenin in rat
    Yan Chen
    Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, 100 Shizi Road, Nanjing 210028, China
    Molecules 15:8478-87. 2010
    ..As flavonoids can interact with raloxifene in vitro, we evaluated the in vivo pharmacokinetics of raloxifene in rats when co-administered with apigenin...
  39. pmc Validated reversed phase-high performance liquid chromatography-diode array detector method for the quantitation of Rutin, a natural immunostimulant for improving survival in aquaculture practice, in toonea sinensis folium
    Yuping Shen
    Department of Chinese Medicine and Pharmacy, School of Pharmacy, Jiangsu University, China
    Pharmacogn Mag 8:49-53. 2012
    ..However, no method for the quantitation of this active ingredient in the herb has been reported to date...
  40. ncbi request reprint [Chromatographic fingerprint of Dipsacus asper and analysis by HPLC-MS]
    Yingjie Wei
    Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China
    Zhongguo Zhong Yao Za Zhi 36:169-74. 2011
    ..The results indicate the HPLC fingerprint of D. asper will show more characters through identification of component structures using an HPLC-ESI-MS method, and will control the quality of D. asper more effectively and reasonable...