Yong Hyun Jeon



  1. Singh T, Jeong S, Lee S, Ha J, Lee I, Kim S, et al. Inverse Agonist of Estrogen-Related Receptor γ Enhances Sodium Iodide Symporter Function Through Mitogen-Activated Protein Kinase Signaling in Anaplastic Thyroid Cancer Cells. J Nucl Med. 2015;56:1690-6 pubmed publisher
    ..These findings suggest that the inverse agonist of ERRγ enhances the responsiveness of radioiodine therapy by modulating NIS function in ATC cells via the regulation of ERRγ and the MAP kinase signaling pathway. ..
  2. Kang S, Lee H, Jeon Y, Singh T, Choi Y, Park J, et al. Combined Fluorescence and Magnetic Resonance Imaging of Primary Macrophage Migration to Sites of Acute Inflammation Using Near-Infrared Fluorescent Magnetic Nanoparticles. Mol Imaging Biol. 2015;17:643-51 pubmed publisher
  3. Kalimuthu S, Zhu L, Oh J, Lee H, Gangadaran P, Rajendran R, et al. Regulated Mesenchymal Stem Cells Mediated Colon Cancer Therapy Assessed by Reporter Gene Based Optical Imaging. Int J Mol Sci. 2018;19: pubmed publisher
    ..In addition, our results provide an innovative therapeutic approach using the Tet-On system to eradicate tumors by administration of MSC-Tet-TK cells with DOX and GCV. ..
  4. Lee S, Kumar D, Li Y, Lee I, Cho S, Kim S, et al. PEGylated crushed gold shell-radiolabeled core nanoballs for in vivo tumor imaging with dual positron emission tomography and Cerenkov luminescent imaging. J Nanobiotechnology. 2018;16:41 pubmed publisher
    ..Taken together, the data provided strong evidence for the application of PEG-124I-Au@AuCBs as promising imaging agents in nuclear medicine imaging of various biological systems, particularly in cancer diagnosis. ..
  5. Kim J, Im C, Yoo E, Ma M, Kim S, Hong E, et al. Identification of Selective ERRγ Inverse Agonists. Molecules. 2016;21:80 pubmed publisher
    ..This novel class of ERRγ inverse agonists shows promise in the development of drugs targeting ERRγ-related diseases. ..
  6. Choi Y, Oh S, Singh T, Ha J, Kim D, Lee S, et al. Visualization of the Biological Behavior of Tumor-Associated Macrophages in Living Mice with Colon Cancer Using Multimodal Optical Reporter Gene Imaging. Neoplasia. 2016;18:133-41 pubmed publisher
  7. Lee S, Yoon G, Lee S, Jeong S, Ahn B, Lim D, et al. Combined Positron Emission Tomography and Cerenkov Luminescence Imaging of Sentinel Lymph Nodes Using PEGylated Radionuclide-Embedded Gold Nanoparticles. Small. 2016;12:4894-4901 pubmed publisher
    ..Taken together, the data provide strong evidence that PEG-RIe-AuNPs are promising as potential lymphatic tracers in biomedical imaging for pre and intraoperative surgical guidance. ..
  8. Singh T, Lee J, Jeon Y. Noninvasive Imaging of Natural Killer Cell-Mediated Apoptosis in a Mouse Tumor Model. Methods Mol Biol. 2016;1441:297-306 pubmed publisher
    ..Here, we describe a noninvasive bioluminescence imaging approach to determine the antitumor effects of NK cell-based therapy by serial imaging of caspase-3-dependent apoptosis in a mouse model of human glioma. ..
  9. Oh S, Li X, Lee H, Singh T, Lee S, Ji H, et al. Non-invasive visualization of mast cell recruitment and its effects in lung cancer by optical reporter gene imaging and glucose metabolism monitoring. Biomaterials. 2017;112:192-203 pubmed publisher

More Information


  1. Ahn S, Lee S, Singh T, Cho S, Kim S, Lee I, et al. Multimodality Imaging of Bone Marrow-Derived Dendritic Cell Migration and Antitumor Immunity. Transl Oncol. 2017;10:262-270 pubmed publisher
  2. Choi Y, Lee H, Lee J, Jeon Y. The combination of ANT2 shRNA and hNIS radioiodine gene therapy increases CTL cytotoxic activity through the phenotypic modulation of cancer cells: combination treatment with ANT2 shRNA and I-131. BMC Cancer. 2013;13:143 pubmed publisher
    ..Our results suggest that combination therapy can be used as a new therapeutic strategy for cancer patients who show resistance to single therapy such as radiation or immunotherapy. ..