Research Topics

Species

Uffe Birk Jensen

Summary

Publications

  1. Blein S, Bardel C, Danjean V, McGuffog L, Healey S, Barrowdale D, et al. An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers. Breast Cancer Res. 2015;17:61 pubmed publisher
    ..This study illustrates how original approaches such as the phylogeny-based method we used can empower classical molecular epidemiological studies aimed at identifying association or risk modification effects. ..
  2. Silvestri V, Barrowdale D, Mulligan A, Neuhausen S, Fox S, Karlan B, et al. Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Res. 2016;18:15 pubmed publisher
    ..e., high histologic grade). These findings could lead to the development of gender-specific risk prediction models and guide clinical strategies appropriate for MBC management. ..
  3. Gunnarsson A, Christensen R, Praetorius J, Jensen U. Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes. Exp Cell Res. 2017;350:368-379 pubmed publisher
    ..Our study also documents a marked change in behaviour upon cell culturing and challenges the way we assess for stemness within the human epidermal basal layer. ..
  4. Christensen R, Owens D, Füchtbauer A, Gunnarsson A, Ramsing M, Füchtbauer E, et al. Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression. Stem Cell Res. 2017;23:109-118 pubmed publisher
    ..In early stages, overexpression of Sca-1 decreases tumour formation while at later stages overexpression of Sca-1 seems to drive tumours towards malignant progression. ..
  5. Pen A, Nyegaard M, Fang M, Jiang H, Christensen R, Mølgaard H, et al. A novel single nucleotide splice site mutation in FHL1 confirms an Emery-Dreifuss plus phenotype with pulmonary artery hypoplasia and facial dysmorphology. Eur J Med Genet. 2015;58:222-9 pubmed publisher
    ..This demonstrated loss of isoform A and B, and an almost 200-fold overexpression of isoform C confirming that lack of FHL1A and overexpression of FHL1C results in an extended phenotype of EDMD as recently shown by Tiffin et al. [2013]. ..
  6. Gunnarsson A, Christensen R, Li J, Jensen U. Global gene expression and comparison between multiple populations in the mouse epidermis. Stem Cell Res. 2016;17:191-202 pubmed publisher
    ..Our data shows that flow cytometry using multicolor panels can identify further subsets of cells within the epidermis and also highlights a marked discrepancy in gene expression between directly isolated cells and tissue cultured cells. ..
  7. Riwaldt S, Monici M, Graver Petersen A, Birk Jensen U, Evert K, Pantalone D, et al. Preparation of A Spaceflight: Apoptosis Search in Sutured Wound Healing Models. Int J Mol Sci. 2017;18: pubmed publisher
    ..Collectively, the performed methods defining analytical protocols proved to be applicable for post-flight analyzes of tissue specimens after sample return. ..