T Jefferson

Summary

Publications

  1. ncbi request reprint Methodological quality of economic modelling studies. A case study with hepatitis B vaccines
    T Jefferson
    Cochrane Vaccines Field, Ministry of Defence, Ash Vale, England
    Pharmacoeconomics 14:251-7. 1998
  2. ncbi request reprint 1st International Symposium on the Evaluation of Safety of Human Vaccines. 22-23 May 2002, Istituto Superiore di Sanitá, Rome, Italy
    Tom Jefferson
    Health Reviews Ltd, Rome, Italy
    Expert Opin Drug Saf 1:195-8. 2002
  3. ncbi request reprint Adverse events after immunisation with aluminium-containing DTP vaccines: systematic review of the evidence
    Tom Jefferson
    Cochrane Vaccines Field and Health Reviews Ltd, Rome, Italy
    Lancet Infect Dis 4:84-90. 2004
  4. ncbi request reprint Selective quotation of evidence in vaccines research
    Tom Jefferson
    Lancet 363:1738. 2004
  5. doi request reprint Wireless capsule endoscopy in Italy: adding context-specific data to the review of the evidence from literature
    Alessandra Lo Scalzo
    Innovation and Development Department HTA Unit, Agenzia Nazionale per i Servizi Sanitari Regionali Agenas, Via Puglie 23, Rome, 00187, Italy
    Int J Technol Assess Health Care 25:297-304. 2009
  6. ncbi request reprint Influenza vaccines in adults
    T Jefferson
    Health Reviews Ltd, Via Adige 28a, 00061 Anguillara Sabazia, Rome, Italy
    Occup Med (Lond) 52:255-8. 2002
  7. ncbi request reprint Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic review
    T Jefferson
    Cochrane Vaccines Field, ASL 20, 15100 Alessandria, Italy
    Lancet 365:773-80. 2005
  8. ncbi request reprint The role of editorial peer review in the evaluation of vaccine safety
    Tom Jefferson
    Cochrane Vaccines Field, 00061 Anguillara Sabazia, Rome, Italy
    Vaccine 22:2073-5. 2004
  9. ncbi request reprint Unintended events following immunization with MMR: a systematic review
    Tom Jefferson
    Reparto Epidemiologia Clinica, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Vaccine 21:3954-60. 2003
  10. ncbi request reprint Systematic review of the effects of pertussis vaccines in children
    Tom Jefferson
    Health Reviews Ltd, Via Adige 28a, 00061 Anguillara Sabazia, Rome, Italy
    Vaccine 21:2003-14. 2003

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Methodological quality of economic modelling studies. A case study with hepatitis B vaccines
    T Jefferson
    Cochrane Vaccines Field, Ministry of Defence, Ash Vale, England
    Pharmacoeconomics 14:251-7. 1998
    ..Editors of specialist and general medical journals should agree on and enforce common explicit guidelines for study conduct and reporting, following the example of the British Medical Journal...
  2. ncbi request reprint 1st International Symposium on the Evaluation of Safety of Human Vaccines. 22-23 May 2002, Istituto Superiore di Sanitá, Rome, Italy
    Tom Jefferson
    Health Reviews Ltd, Rome, Italy
    Expert Opin Drug Saf 1:195-8. 2002
    ....
  3. ncbi request reprint Adverse events after immunisation with aluminium-containing DTP vaccines: systematic review of the evidence
    Tom Jefferson
    Cochrane Vaccines Field and Health Reviews Ltd, Rome, Italy
    Lancet Infect Dis 4:84-90. 2004
    ..05 [1.25-3.38]). We found no evidence that aluminium salts in vaccines cause any serious or long-lasting adverse events. Despite a lack of good-quality evidence we do not recommend that any further research on this topic is undertaken...
  4. ncbi request reprint Selective quotation of evidence in vaccines research
    Tom Jefferson
    Lancet 363:1738. 2004
  5. doi request reprint Wireless capsule endoscopy in Italy: adding context-specific data to the review of the evidence from literature
    Alessandra Lo Scalzo
    Innovation and Development Department HTA Unit, Agenzia Nazionale per i Servizi Sanitari Regionali Agenas, Via Puglie 23, Rome, 00187, Italy
    Int J Technol Assess Health Care 25:297-304. 2009
    ....
  6. ncbi request reprint Influenza vaccines in adults
    T Jefferson
    Health Reviews Ltd, Via Adige 28a, 00061 Anguillara Sabazia, Rome, Italy
    Occup Med (Lond) 52:255-8. 2002
    ..As the yearly levels of circulating A and B viruses are difficult to predict during the decision time for a vaccination campaign, there is a considerable element of uncertainty regarding the likely effectiveness of 'this year's' vaccine...
  7. ncbi request reprint Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic review
    T Jefferson
    Cochrane Vaccines Field, ASL 20, 15100 Alessandria, Italy
    Lancet 365:773-80. 2005
    ..We aimed to assess evidence of efficacy and effectiveness of live attenuated and inactivated influenza vaccines in children up to 16 years of age...
  8. ncbi request reprint The role of editorial peer review in the evaluation of vaccine safety
    Tom Jefferson
    Cochrane Vaccines Field, 00061 Anguillara Sabazia, Rome, Italy
    Vaccine 22:2073-5. 2004
  9. ncbi request reprint Unintended events following immunization with MMR: a systematic review
    Tom Jefferson
    Reparto Epidemiologia Clinica, Istituto Superiore di Sanita, Viale Regina Elena, 299 00161 Rome, Italy
    Vaccine 21:3954-60. 2003
    ..The evidence of adverse events following immunization with MMR cannot be separated from its role in preventing the target diseases...
  10. ncbi request reprint Systematic review of the effects of pertussis vaccines in children
    Tom Jefferson
    Health Reviews Ltd, Via Adige 28a, 00061 Anguillara Sabazia, Rome, Italy
    Vaccine 21:2003-14. 2003
    ..To assess the efficacy and safety of whole-cell and acellular pertussis vaccines administered to children singly or within diphtheria, tetanus and pertussis (DTP) vaccines...
  11. ncbi request reprint Microbial challenge studies--a challenge worth accepting
    Tom Jefferson
    Cochrane Vaccines Field, 00061 Anguillara Sabazia, Rome, Italy
    Lancet 366:531-3. 2005
  12. ncbi request reprint Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review
    T Jefferson
    Cochrane Vaccines Field, ASL 20, 15100 Alessandria, Italy
    Lancet 366:1165-74. 2005
    ..Influenza vaccination of elderly individuals is recommended worldwide. Our aim was to review the evidence of efficacy and effectiveness of influenza vaccines in individuals aged 65 years or older...
  13. ncbi request reprint Antivirals for influenza in healthy adults: systematic review
    T Jefferson
    Cochrane Vaccines Field, ASL 20, 15100 Alessandria, Italy
    Lancet 367:303-13. 2006
    ..Use of antivirals is recommended for the control of seasonal and pandemic influenza. Our aim was to review the evidence of efficacy, effectiveness, and safety of registered antivirals against naturally occurring influenza in healthy adults...
  14. ncbi request reprint Informed choice and balance are victims of the MMR-autism saga
    Tom Jefferson
    Lancet Infect Dis 4:135-6. 2004
  15. pmc Why the MRC randomized trials of whooping cough (pertussis) vaccines remain important more than half a century after they were done
    T Jefferson
    J R Soc Med 100:343-5. 2007
  16. ncbi request reprint Hepatitis B vaccination: risk-benefit profile and the role of systematic reviews in the assessment of causality of adverse events following immunisation
    Tom Jefferson
    Department of Epidemiology and Biostatistics, Istituto Superiore di Sanita, Roma, Italy
    J Med Virol 67:451-3. 2002
    ..The availability of subsequent negative association studies provided further reassurance. It is essential to rely on well-conducted systematic reviews to produce valid and reliable estimates of the risk-benefit profile...
  17. ncbi request reprint Do vaccines make best use of available resources? (in other words are they cost-effective?)
    T Jefferson
    Professor Tom Jefferson, UK Cochrane Centre and Cochrane Vaccines Field, Mytchett Camberley, UK
    Vaccine 17:S69-73. 1999
    ..The use of economic logic can also be applied to prioritize research into vaccines, both on the basis of ability of the target population to benefit and of the availability of good quality evidence...
  18. ncbi request reprint Cochrane reviews and systematic reviews of economic evaluations. Amantadine and rimantadine in the prevention and treatment of influenza
    T Jefferson
    UK Cochrane Centre, Camberley, Surrey, England
    Pharmacoeconomics 16:85-9. 1999
    ..Additionally, they can be used to focus clinical trial questions and provide strategic insight regarding the state-of-the-art knowledge of effects and economics of compounds in a specific field...
  19. ncbi request reprint Effects of editorial peer review: a systematic review
    Tom Jefferson
    Health Reviews Ltd, Rome, Italy
    JAMA 287:2784-6. 2002
    ..Editorial peer review is widely used to select submissions to journals for publication and is presumed to improve their usefulness. Sufficient research on peer review has been published to consider a synthesis of its effects...
  20. ncbi request reprint Hepatitis B vaccination and multiple sclerosis: evidence from a systematic review
    V Demicheli
    Cochrane Vaccines Field, Alessandria, Italy
    J Viral Hepat 10:343-4. 2003
  21. ncbi request reprint Physical interventions to interrupt or reduce the spread of respiratory viruses: a Cochrane review
    T Jefferson
    Vaccines Field, The Cochrane Collaboration, Roma, Italy
    Health Technol Assess 14:347-476. 2010
    ..Viral epidemics or pandemics of acute respiratory infections like influenza or severe acute respiratory syndrome pose a world-wide threat. Antiviral drugs and vaccinations may be insufficient to prevent catastrophe...
  22. ncbi request reprint Neuraminidase inhibitors for preventing and treating influenza in healthy adults: a Cochrane review
    T Jefferson
    Vaccines Field, The Cochrane Collaboration, Roma, Italy
    Health Technol Assess 14:355-458. 2010
    ..Neuraminidase inhibitors (NI) are recommended for use against influenza and its complications in inter-pandemic years and during pandemics...
  23. pmc Relation of study quality, concordance, take home message, funding, and impact in studies of influenza vaccines: systematic review
    T Jefferson
    Cochrane Vaccines Field, ASL Azienda Sanitaria Locale AL 20, 15100 Alessandria, Italy
    BMJ 338:b354. 2009
    ..To explore the relation between study concordance, take home message, funding, and dissemination of comparative studies assessing the effects of influenza vaccines...
  24. ncbi request reprint Methodological issues arising from systematic reviews of the evidence of safety of vaccines
    D Price
    Cochrane Vaccines Field and Health Reviews Ltd, Cochrane Centre, Summertown Pavilion, Middle Way Summertown, Oxford OX2 7LG, UK
    Vaccine 22:2080-4. 2004
    ..Standardizing both the indexing of adverse event data on electronic libraries and their reporting would improve the potential of systematic reviews of vaccine to draw accurate conclusions about the safety of a vaccine...
  25. ncbi request reprint Influenza like Illness (ILI): prescribing behaviour of 83 sentry doctors in Lazio region in the period 2001-2002. Is it adherent to Italian ILI guidelines?
    L Orzella
    Agency of Public Health ASP Lazio Region, Rome, Italy
    Ann Ig 19:19-26. 2007
    ..Overall, doctors' attitude in prescribing is generally coherent with Italian Guidelines on ILI even though a high variability still persists...
  26. ncbi request reprint Effectiveness of immune globulins in preventing infectious hepatitis and hepatitis A: a systematic review
    E Bianco
    National Health Institute, Rome, Italy
    Dig Liver Dis 36:834-42. 2004
    ..To assess the effectiveness and safety of immune globulins in preventing infectious hepatitis and hepatitis A...
  27. pmc Attenti alle bufale ("beware of red herrings"), or, how to make evidence-based medicine work for you
    Tom Jefferson
    Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
    J R Soc Med 99:625-7. 2006
  28. pmc Implementing a guideline for the treatment of type 2 diabetics: results of a cluster-randomized controlled trial (C-RCT)
    Carla Perria
    Community Health Unit, Lazio Region Public Health Agency, Rome, Italy
    BMC Health Serv Res 7:79. 2007
    ..We assessed the effectiveness of different strategies for the implementation of an evidence-based guideline for the management of non-complicated type 2 diabetes among General Practitioners (GPs) of Lazio region...
  29. ncbi request reprint Measuring the quality of editorial peer review
    Tom Jefferson
    Health Reviews Ltd, Rome, Italy
    JAMA 287:2786-90. 2002
    ..The quality of a process can only be tested against its agreed objectives. Editorial peer-review is widely used, yet there appears to be little agreement about how to measure its effects or processes...
  30. ncbi request reprint Quality of systematic reviews of economic evaluations in health care
    Tom Jefferson
    Cochrane Health Economics Group, Rome, Italy
    JAMA 287:2809-12. 2002
    ..Measures taken by the research community to address the issue included the promulgation of guidelines and the publicizing of good practice in economic evaluation...
  31. pmc Influenza vaccination: policy versus evidence
    Tom Jefferson
    Cochrane Vaccines Field, Anguillara Sabazia, Roma 00061, Italy
    BMJ 333:912-5. 2006
  32. pmc Bufale spotting, part 8: assessing a letter to a journal
    Tom Jefferson
    Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
    J R Soc Med 100:551. 2007
  33. pmc Bufale spotting, part two: assessing systematic reviews
    Tom Jefferson
    Cochrane Vaccines Field, Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
    J R Soc Med 100:180-1. 2007
  34. pmc Bufale spotting, part three: assessing editorials
    Tom Jefferson
    Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
    J R Soc Med 100:267. 2007
  35. pmc Bufale Spotting, part 9: assessing an economic evaluation
    Tom Jefferson
    Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group 00061 Anguillara Sabazia, Rome, Italy
    J R Soc Med 101:175-6. 2008
  36. pmc Bufale spotting, Part 10: Assessing a journal
    Tom Jefferson
    Cochrane Vaccines Field and Cochrane Acute Respiratory Infections Group, 00061 Anguillara Sabazia, Rome, Italy
    J R Soc Med 101:235-6. 2008
  37. pmc An emergency clinical pathway for stroke patients--results of a cluster randomised trial (isrctn41456865)
    Assunta De Luca
    Public Health Agency of the Latium Region, Rome, Italy
    BMC Health Serv Res 9:14. 2009
    ..Emergency Clinical Pathways (ECP) for stroke have never been tested in randomized controlled trials (RCTs)...
  38. pmc Balancing benefits and harms in health care: observational data on harm are already included in systematic reviews
    Tom Jefferson
    BMJ 327:750. 2003
  39. pmc How to deal with influenza?
    Tom Jefferson
    BMJ 329:633-4. 2004
  40. ncbi request reprint [Evidence-based emergency pathways for patients with acute coronary syndrome]
    Stefania Cardo
    Agenzia di Sanità Pubblica del Lazio
    Ital Heart J 6:27S-40S. 2005
    ....
  41. ncbi request reprint The Brighton Collaboration: addressing the need for standardized case definitions of adverse events following immunization (AEFI)
    Jan Bonhoeffer
    University Children s Hospital Basel, Basel, Switzerland
    Vaccine 21:298-302. 2002
    ..Comparability requires the availability of standardized case definitions for adverse events following immunization (AEFI) and guidelines for case determination, recording and data presentation...
  42. ncbi request reprint A systematic approach to medical decision-making of uncommon clinical pictures: a case of ulcerative skin lesions by palm tree thorn injury and a one-year follow-up
    Salvatore Corrao
    Unit of Clinical Methodology, Epidemiology and Statistics, A R N A S Civico e Benfratelli Hospital Trust, Palermo, Italy
    Med Inform Internet Med 30:203-10. 2005
    ..The method we have proposed can be applied in every area of the world, especially in rural areas. Finally, an Internet-shared database of uncommon clinical pictures with critically appraised topics could be useful in saving more time...
  43. ncbi request reprint Inactivated influenza vaccines in the elderly--are you sure?
    Tom Jefferson
    Cochrane Vaccines Field, 15100 Alessandria, Italy
    Lancet 370:1199-200. 2007
  44. ncbi request reprint The Brighton Collaboration-enhancing vaccine safety
    Jan Bonhoeffer
    Division of Pediatrics Infectious Diseases and Vaccines, University Children s Hospital, P O Box 8, 4005 Basel, Switzerland
    Vaccine 22:2046. 2004
  45. ncbi request reprint Influenza vaccination for elderly people and their care workers
    Tom Jefferson
    Lancet 369:1857-8. 2007
  46. ncbi request reprint A systematic literature review of the clinical and cost-effectiveness of hadron therapy in cancer
    Mark Lodge
    Cochrane Cancer Network, Oxford, UK
    Radiother Oncol 83:110-22. 2007
    ..In view of the continued increase in the number of hadron (i.e. neutron, proton and light or heavy ion) therapy (HT) centres we performed a systematic literature review to identify reports of the efficacy of HT...
  47. pmc Bioterrorism and compulsory vaccination
    Tom Jefferson
    BMJ 329:524-5. 2004
  48. ncbi request reprint The use of hepatitis A vaccine in Italy--evidence-based recommendations from an expert panel
    Alfonso Mele
    Vaccine 21:2223. 2003
  49. ncbi request reprint Economic analysis of influenza vaccination and treatment
    Tom Jefferson
    Ann Intern Med 138:607; author reply 608-9. 2003
  50. ncbi request reprint Journals: how to decide what's worth publishing
    Tom Jefferson
    Nature 421:209-10. 2003
  51. ncbi request reprint Reduction of inappropriate hospital admissions of children with influenza-like illness through the implementation of specific guidelines: a case-controlled study
    Giulio De Marco
    Department of Pediatrics, University of Naples Federico II, Naples, Italy
    Pediatrics 116:e506-11. 2005
    ..The aim of this study was to evaluate whether application of these CPGs reduced the rate of inappropriate hospital admissions...
  52. pmc Detecting plagiarism: current quality control systems don't work
    Tom Jefferson
    BMJ 333:706. 2006
  53. pmc Author's response to influenza vaccination: policy v evidence
    Tom Jefferson
    BMJ 333:1172. 2006
  54. pmc Look at all the evidence before stockpiling amantadine
    Tom Jefferson
    BMJ 334:439. 2007
  55. ncbi request reprint A withdrawn prepublication
    Tom Jefferson
    Lancet 369:901-2. 2007
  56. ncbi request reprint Change from oral poliovirus vaccine to inactivated poliovirus vaccine
    Alfonso Mele
    Lancet 360:1178. 2002
  57. ncbi request reprint Standardized case definitions of adverse events following immunization (AEFI)
    Jan Bonhoeffer
    Vaccine 22:547-50. 2004