Assessment of corticosteroid replacement therapy in adults with adrenal insufficiencyW Jeffcoate
Department of Diabetes and Endocrinology, City Hospital, Nottingham, UK
Ann Clin Biochem 36:151-7. 1999
..In such circumstances, a cortisol day curve is likely to be of more value than measurement of UFC...
The Charcot footW Jeffcoate
Department of Diabetes and Endocrinology, City Hospital, Nottingham, UK
Diabet Med 17:253-8. 2000
..To review the clinical manifestations of the Charcot foot in diabetes mellitus, with particular reference to theories concerning aetiology...
Why did the 5th Earl of Derby die?W Jeffcoate
Department of Diabetes and Endocrinology, City Hospital, NG5 1PB, Nottingham, UK
Lancet 357:1876-9. 2001
..His death was so significant that the historian John Stow recorded his illness in great detail (Fig. 1).(1) Stow's remarkable account is compatible with a sinister interpretation of the cause...
Growth hormone therapy and its relationship to insulin resistance, glucose intolerance and diabetes mellitus: a review of recent evidenceWilliam Jeffcoate
Department of Diabetes and Endocrinology, City Hospital, Nottingham, England
Drug Saf 25:199-212. 2002
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Diabetic foot ulcersWilliam J Jeffcoate
Department of Diabetes and Endocrinology, City Hospital, Nottingham, UK
Lancet 361:1545-51. 2003
..Furthermore, the pathological processes are poorly understood and poorly taught and communication between the many specialties involved is disjointed and insensitive to the needs of patients...
Controversies in diagnosing and managing osteomyelitis of the foot in diabetesWilliam J Jeffcoate
Department of Diabetes and Endocrinology, City Hospital, Nottingham, United Kingdom
Clin Infect Dis 39:S115-22. 2004
..We review the microbiology of osteomyelitis of the foot in diabetes, the benefits and limitations of various diagnostic procedures, and the evidence for the effectiveness of both surgical and nonsurgical approaches to management...
Use of the SINBAD classification system and score in comparing outcome of foot ulcer management on three continentsPaul Ince
Foot Ulcer Trials Unit, Diabetes and Endocrinology, City Hospital, Nottingham, UK
Diabetes Care 31:964-7. 2008
..To compare populations with and outcomes of diabetic foot ulcers managed in the U.K., Germany, Tanzania, and Pakistan and to explore the use of a new score of ulcer type in comparing outcomes among different countries...
The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetesWilliam J Jeffcoate
Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, City Hospital, Nottingham NG5 1PB, UK
Lancet 366:2058-61. 2005
..The potential role of proinflammatory cytokines suggests the possibility of new treatments for this sometimes devastating complication of diabetes...
Rate of healing of neuropathic ulcers of the foot in diabetes and its relationship to ulcer duration and ulcer areaPaul Ince
Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, City Hospital, Nottingham, NG5 1PB, UK
Diabetes Care 30:660-3. 2007
..To examine the outcome of neuropathic foot ulcers and to seek associations between healing and features of the ulcers at baseline...
Temporal association between the incidence of foot ulceration and the start of dialysis in diabetes mellitusFrances L Game
Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, City Hospital, and Department of Epidemiology and Public Health, University of Nottingham NG5 1PB, UK
Nephrol Dial Transplant 21:3207-10. 2006
..The aim of this study was to seek a temporal association between the start of renal replacement therapy (RRT) and the first recorded foot ulcer in diabetes...
Theories concerning the pathogenesis of the acute charcot foot suggest future therapyWilliam J Jeffcoate
Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, City Hospital, Nottingham NG5 1PB, UK
Curr Diab Rep 5:430-5. 2005
..The recognition that the acute Charcot foot is essentially an inflammatory arthropathy suggests new options for the management of this potentially devastating condition...
Wound healing--a practical algorithmWilliam J Jeffcoate
Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, Nottingham University Hospitals Trust, Nottingham, UK
Diabetes Metab Res Rev 28:85-8. 2012
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Assessing the outcome of the management of diabetic foot ulcers using ulcer-related and person-related measuresWilliam J Jeffcoate
Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, City Hospital, Nottingham, UK
Diabetes Care 29:1784-7. 2006
..The purpose of this study was to compare different outcome measures in the audit of management of diabetic foot ulcers..
Abnormalities of vasomotor regulation in the pathogenesis of the acute charcot foot of diabetes mellitusWilliam J Jeffcoate
Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, City Hospital, Nottingham, UK
Int J Low Extrem Wounds 4:133-7. 2005
..If this hypothesis is confirmed, it would suggest the option of new effective treatments for this sometimes devastating disorder...
Charcot neuro-osteoarthropathyWilliam J Jeffcoate
Department of Diabetes and Endocrinology, Nottingham University Hospitals Trust, City Hospital Campus, Nottingham NG5 1PB, UK
Diabetes Metab Res Rev 24:S62-5. 2008
..The likely central role for the RANKL/OPG pathway suggests new possibilities for future treatments...
Wound healing and treatments for people with diabetic foot ulcersWilliam J Jeffcoate
Diabetes Metab Res Rev 20:S78-89. 2004
..There are many applications and dressings that may be chosen to promote healing, but, whichever is selected, wound management has to be integrated into an effective programme of multidisciplinary care...
Off-loading in trials in neuropathic diabetic foot ulceration: no, it's not time for a paradigm shiftWilliam J Jeffcoate
Diabetes Care 27:635-6; author reply 636-7. 2004
Comparison of three systems of classification in predicting the outcome of diabetic foot ulcers in a Brazilian populationMaria Cândida R Parisi
Endocrinology Division, Internal Medicine Department, Medical School, State University of Campinas, Campinas, SP, Brazil
Eur J Endocrinol 159:417-22. 2008
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