Heather B Jaspan

Summary

Publications

  1. doi request reprint Two-year outcomes of children on non-nucleoside reverse transcriptase inhibitor and protease inhibitor regimens in a South African pediatric antiretroviral program
    Heather B Jaspan
    School of Child and Adolescent Health, University of Cape Town, South Africa
    Pediatr Infect Dis J 27:993-8. 2008
  2. pmc Community perspectives on the ethical issues surrounding adolescent HIV vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa
    Vaccine 26:5679-83. 2008
  3. ncbi request reprint Preventing neonatal HIV: a review
    Heather B Jaspan
    Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70119, USA
    Curr HIV Res 1:321-7. 2003
  4. ncbi request reprint Brief report: methods for collecting sexual behaviour information from South African adolescents--a comparison of paper versus personal digital assistant questionnaires
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Faculty of Health Sciences, PO Box 13801 Mowbray 7705, South Africa
    J Adolesc 30:353-9. 2007
  5. ncbi request reprint Adolescent HIV prevalence, sexual risk, and willingness to participate in HIV vaccine trials
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 39:642-8. 2006
  6. pmc Sexual health, HIV risk, and retention in an adolescent HIV-prevention trial preparatory cohort
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 49:42-6. 2011
  7. ncbi request reprint Amniotic fluid has higher relative levels of lentivirus-specific antibodies than plasma and can contain neutralizing antibodies
    Heather B Jaspan
    Interdisciplinary Program in Molecular and Cellular Biology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    J Clin Virol 31:190-7. 2004
  8. pmc The role of polyclonal intravenous immunoglobulin in treating HIV-infected children with severe bacterial infections: a retrospective cohort study
    Lyen C Huang
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
    BMC Infect Dis 8:127. 2008
  9. ncbi request reprint Scientific justification for the participation of children and adolescents in HIV-1 vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, South Africa
    S Afr Med J 95:685-7. 2005
  10. pmc Effect of caregivers' depression and alcohol use on child antiretroviral adherence in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS Patient Care STDS 25:595-600. 2011

Detail Information

Publications15

  1. doi request reprint Two-year outcomes of children on non-nucleoside reverse transcriptase inhibitor and protease inhibitor regimens in a South African pediatric antiretroviral program
    Heather B Jaspan
    School of Child and Adolescent Health, University of Cape Town, South Africa
    Pediatr Infect Dis J 27:993-8. 2008
    ..Few data exist on the efficacy of the limited regimens for children with HIV, which are available in sub-Saharan Africa...
  2. pmc Community perspectives on the ethical issues surrounding adolescent HIV vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, South Africa
    Vaccine 26:5679-83. 2008
    ..In general, ethical adolescent HIV vaccine trials will be feasible in this community...
  3. ncbi request reprint Preventing neonatal HIV: a review
    Heather B Jaspan
    Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70119, USA
    Curr HIV Res 1:321-7. 2003
    ..However, post-natal transmission via breast milk remains a major challenge. As we continue to find cost-effective answers to protect infants worldwide, the search for a HIV-1 vaccine continues...
  4. ncbi request reprint Brief report: methods for collecting sexual behaviour information from South African adolescents--a comparison of paper versus personal digital assistant questionnaires
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Faculty of Health Sciences, PO Box 13801 Mowbray 7705, South Africa
    J Adolesc 30:353-9. 2007
    ..Subjectively, adolescents found the use of PDA to be simple and confidential. PDA may be a useful method to collect sensitive, self-reported information from adolescents in resource-limited settings...
  5. ncbi request reprint Adolescent HIV prevalence, sexual risk, and willingness to participate in HIV vaccine trials
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 39:642-8. 2006
    ..To determine human immunodeficiency virus (HIV) prevalence, sexual risk behaviors, and attitudes toward HIV vaccine trials among 11-19 year-olds in a peri-urban community near Cape Town, South Africa...
  6. pmc Sexual health, HIV risk, and retention in an adolescent HIV-prevention trial preparatory cohort
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 49:42-6. 2011
    ..Although adolescents are at high risk for human immunodeficiency virus (HIV) infection, they have not been, included in HIV vaccine trials...
  7. ncbi request reprint Amniotic fluid has higher relative levels of lentivirus-specific antibodies than plasma and can contain neutralizing antibodies
    Heather B Jaspan
    Interdisciplinary Program in Molecular and Cellular Biology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    J Clin Virol 31:190-7. 2004
    ..Natural protective mechanisms involving lentivirus-specific antibodies may therefore exist to limit in utero transmission of lentiviruses...
  8. pmc The role of polyclonal intravenous immunoglobulin in treating HIV-infected children with severe bacterial infections: a retrospective cohort study
    Lyen C Huang
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
    BMC Infect Dis 8:127. 2008
    ..We examined the impact of IVIG as an adjuvant therapy in reducing mortality and length of hospital stay in HIV-infected children with serious bacterial infections...
  9. ncbi request reprint Scientific justification for the participation of children and adolescents in HIV-1 vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, South Africa
    S Afr Med J 95:685-7. 2005
  10. pmc Effect of caregivers' depression and alcohol use on child antiretroviral adherence in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    AIDS Patient Care STDS 25:595-600. 2011
    ..99). Pediatric adherence is affected by caregiver alcohol use, but caregiver relationship to the child is most important. This small study suggests that interventions should aim to keep mothers healthy and alive, as well as alcohol-free...
  11. ncbi request reprint Inclusion of adolescents in preventive HIV vaccine trials: public health policy and research design at a crossroads
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, South Africa
    J Acquir Immune Defic Syndr 47:86-92. 2008
    ..This article examines these issues and proposes specific next steps to facilitate the routine inclusion of this high-priority population in preventive HIV vaccine trials as early and seamlessly as possible...
  12. pmc Quantitative competitive reverse transcription polymerase chain reaction is not a useful method for quantification of CD4 and CD8 cell status during HIV infection
    Heather B Jaspan
    Interdisciplinary Program in Molecular and Cellular Biology Tulane University School of Medicine, New Orleans, LA 70112, USA
    J Negat Results Biomed 2:2. 2003
    ..Such a method would also be useful in assessing the immune status of patients retrospectively...
  13. pmc Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials
    Lycias Zembe
    Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    PLoS ONE 6:e26096. 2011
    ....
  14. ncbi request reprint Expression of granzyme B mRNA is altered in human immunodeficiency virus infected patients
    Heather B Jaspan
    Molecular and Cellular Biology Program, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA
    Exp Mol Pathol 74:13-6. 2003
    ..Cell-mediated cytotoxicity during HIV-1 infection may be impaired due to a deficient quantity of active cytotoxic granules or to their abnormal regulation...
  15. ncbi request reprint The maturing immune system: implications for development and testing HIV-1 vaccines for children and adolescents
    Heather B Jaspan
    AIDS 20:483-94. 2006