Jie Zhang

Summary

Country: Japan

Publications

  1. ncbi request reprint Capsaicin inhibits growth of adult T-cell leukemia cells
    Jie Zhang
    Department of Pathology First Unit, Shimane Medical University, 89 1 Enya cho, Izumo, Shimane 693 8501, Japan
    Leuk Res 27:275-83. 2003
  2. doi request reprint Kinetic study of cytochrome P450 by capillary electrophoretically mediated microanalysis
    Jie Zhang
    Laboratory for Pharmaceutical Analysis, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Electrophoresis 29:3694-700. 2008
  3. pmc Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis
    Christopher G De Vry
    Department of Research, Corgentech, Inc, South San Francisco, California, USA
    Gut 56:524-33. 2007
  4. ncbi request reprint Effect of operating parameters and reactor structure on moderate temperature dry desulfurization
    Jie Zhang
    Key Laboratory for Thermal Science and Power Engineering of Ministry of Education, Department of Thermal Engineering, Tsinghua University, Beijing 100084, China
    Environ Sci Technol 40:4300-5. 2006
  5. ncbi request reprint Novel kinetic and background current selectivity in the even harmonic components of fourier transformed square-wave voltammograms of surface-confined azurin
    Jie Zhang
    School of Chemistry, Monash University, Clayton, Victoria 3800, Australia
    J Phys Chem B 109:8935-47. 2005
  6. ncbi request reprint Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma
    Salvatore Cuzzocrea
    Institute of Pharmacology, School of Medicine, University of Messina, Torre Biologica, Policlinico Universitario Via C Valeria, Gazzi, 98100 Messina, Italy
    J Pharmacol Exp Ther 319:127-38. 2006
  7. ncbi request reprint Application of power spectra patterns in Fourier transform square wave voltammetry to evaluate electrode kinetics of surface-confined proteins
    Barry D Fleming
    School of Chemistry, Monash University, Victoria 3800, Australia
    Anal Chem 78:2948-56. 2006
  8. ncbi request reprint [Induction of apoptosis by mifepristone in androgen-independent prostate cancer cell lines in vitro]
    Hui Zhang
    Department of Urology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China
    Zhonghua Wai Ke Za Zhi 44:382-5. 2006
  9. ncbi request reprint Blockade of experimental atopic dermatitis via topical NF-kappaB decoy oligonucleotide
    Maya Dajee
    Department of Research, Corgentech Inc, South San Francisco, California, USA
    J Invest Dermatol 126:1792-803. 2006
  10. ncbi request reprint Cilostazol protects diabetic rats from vascular inflammation via nuclear factor-kappa B-dependent down-regulation of vascular cell adhesion molecule-1 expression
    Ling Gao
    Center of Scientific Research, and Department of Endocrinology and Metabolism, Shandong Provincial Hospital, Jinan, Shandong 250021, China, and Department of Neurology, Case Western Reserve University, Cleveland, OH, USA
    J Pharmacol Exp Ther 318:53-8. 2006

Collaborators

  • Fei Chen
  • Salvatore Cuzzocrea
  • Jie Sun
  • G M Dubowchik
  • R Kluger
  • Xiu Jie Wang
  • Shu Lan Yuan
  • Bingzhi Yu
  • Christopher G De Vry
  • Maya Dajee
  • Yan Rong Lu
  • Zhen Dou
  • Benchaporn Lertanantawong
  • Haini Liao
  • Shun Lu
  • Maria Wojewodzka
  • Xiurong Zhao
  • Hongtao Li
  • Xiaojun Han
  • Guiying Zhu
  • Qiang Liu
  • Jing Wang
  • Shuang Yang
  • Alan M Bond
  • Radha Shyamsundar
  • Srinivasa Prasad
  • Rolf O Ehrhardt
  • Tony Muchamuel
  • Tina Le
  • Brian Schryver
  • Leslie M McEvoy
  • Laszlo Komuves
  • Christi Parham
  • Kim Mai
  • Barry D Fleming
  • Weizheng Xu
  • Hui Zhang
  • Ling Gao
  • Baolu Zhao
  • Lucio Tentori
  • Susan P Yates
  • Yu Rui Fu
  • Wen Fu Zeng
  • Bo Tao Liu
  • Yue Ming He
  • Susan Cannan
  • Ying Liu
  • Guy N L Jameson
  • Cai Cun Zhou
  • Yueting Zhang
  • Zhihong Zong
  • Wen Xiu Yang
  • Jin Liu
  • Hong Yan Fu
  • Yong Wei
  • Yulan Liu
  • Yu Wen Ke
  • Takashi Minami
  • Xue Li
  • Anthony P O'Mullane
  • David Castle
  • Mei Lin Liao
  • Zi Ming Li
  • Werasak Surareungchai
  • Jie Jun Wang
  • Zhen Zhou
  • Anna Castle
  • Mithran Somasundrum
  • Gabor Szabo
  • Svetlana Shestopal
  • Jia Qing Xiang
  • Xiao Yan Zhou
  • Hai Quan Chen
  • Wei Zhong He
  • Jennifer Hoffman
  • Sarvesh Adda
  • Chuan Qin
  • Zhujuan Xiong
  • Feng Shao
  • Xiujie Wang
  • Jian Min Zhou
  • Ping Lin
  • Qi Chen
  • Radhika Garlapati
  • Marcin Kruszewski
  • Edmond Massuda
  • James C Grotta
  • Yaying Wu
  • Jay Knipe
  • Shelly Ren

Detail Information

Publications54

  1. ncbi request reprint Capsaicin inhibits growth of adult T-cell leukemia cells
    Jie Zhang
    Department of Pathology First Unit, Shimane Medical University, 89 1 Enya cho, Izumo, Shimane 693 8501, Japan
    Leuk Res 27:275-83. 2003
    ..In addition, the Bcl-2 level was found to be decreased. Based on these findings, capsaicin may be considered for chemoprevention of ATL...
  2. doi request reprint Kinetic study of cytochrome P450 by capillary electrophoretically mediated microanalysis
    Jie Zhang
    Laboratory for Pharmaceutical Analysis, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Electrophoresis 29:3694-700. 2008
    ..6+/-8.3 and 19.1+/-2.4 microM, respectively, which are consistent with off-line assay and previously reported values...
  3. pmc Non-viral delivery of nuclear factor-kappaB decoy ameliorates murine inflammatory bowel disease and restores tissue homeostasis
    Christopher G De Vry
    Department of Research, Corgentech, Inc, South San Francisco, California, USA
    Gut 56:524-33. 2007
    ..Nuclear factor-kappaB (NF-kappaB) is a key transcriptional regulator of inflammatory bowel disease (IBD)...
  4. ncbi request reprint Effect of operating parameters and reactor structure on moderate temperature dry desulfurization
    Jie Zhang
    Key Laboratory for Thermal Science and Power Engineering of Ministry of Education, Department of Thermal Engineering, Tsinghua University, Beijing 100084, China
    Environ Sci Technol 40:4300-5. 2006
    ....
  5. ncbi request reprint Novel kinetic and background current selectivity in the even harmonic components of fourier transformed square-wave voltammograms of surface-confined azurin
    Jie Zhang
    School of Chemistry, Monash University, Clayton, Victoria 3800, Australia
    J Phys Chem B 109:8935-47. 2005
    ....
  6. ncbi request reprint Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma
    Salvatore Cuzzocrea
    Institute of Pharmacology, School of Medicine, University of Messina, Torre Biologica, Policlinico Universitario Via C Valeria, Gazzi, 98100 Messina, Italy
    J Pharmacol Exp Ther 319:127-38. 2006
    ..Taken together, our results indicate that PARG activity modulates the inflammatory response and tissue injury events associated with spinal cord trauma and participate in target organ damage under these conditions...
  7. ncbi request reprint Application of power spectra patterns in Fourier transform square wave voltammetry to evaluate electrode kinetics of surface-confined proteins
    Barry D Fleming
    School of Chemistry, Monash University, Victoria 3800, Australia
    Anal Chem 78:2948-56. 2006
    ....
  8. ncbi request reprint [Induction of apoptosis by mifepristone in androgen-independent prostate cancer cell lines in vitro]
    Hui Zhang
    Department of Urology, Shandong Provincial Hospital, Shandong University, Jinan 250021, China
    Zhonghua Wai Ke Za Zhi 44:382-5. 2006
    ..To investigate the effects of mifepristone on cell proliferation of human androgen-independent prostate carcinoma cell lines DU-145, PC-3 in vitro and the possible mechanisms involved...
  9. ncbi request reprint Blockade of experimental atopic dermatitis via topical NF-kappaB decoy oligonucleotide
    Maya Dajee
    Department of Research, Corgentech Inc, South San Francisco, California, USA
    J Invest Dermatol 126:1792-803. 2006
    ..Thus, topical NF-kappaB Decoy provides a novel mechanism of reducing chronic skin inflammation with improved skin homeostasis and minimal side effects...
  10. ncbi request reprint Cilostazol protects diabetic rats from vascular inflammation via nuclear factor-kappa B-dependent down-regulation of vascular cell adhesion molecule-1 expression
    Ling Gao
    Center of Scientific Research, and Department of Endocrinology and Metabolism, Shandong Provincial Hospital, Jinan, Shandong 250021, China, and Department of Neurology, Case Western Reserve University, Cleveland, OH, USA
    J Pharmacol Exp Ther 318:53-8. 2006
    ..More importantly, our mechanistic studies suggested that cilostazol controls the VCAM-1 overexpression via inhibiting the activation of nuclear factor-kappaB...
  11. ncbi request reprint Growth inhibition of high-intensity focused ultrasound on hepatic cancer in vivo
    Xiu Jie Wang
    Division of Experimental Oncology, Key Laboratory of Biotherapy of Human Diseases of Ministry of Education, PR China
    World J Gastroenterol 11:4317-20. 2005
    ..To investigate the damaging effect of high-intensity focused ultrasound (HIFU) on cancer cells and the inhibitory effect on tumor growth...
  12. ncbi request reprint Kinetic study of cytochrome P450 3A4 activity on warfarin by capillary electrophoresis with fluorescence detection
    Jie Zhang
    Laboratory of Pharmaceutical Chemistry and Drug Analysis, Faculty of Pharmaceutical Sciences, K U Leuven, Van Evenstraat 4, B 3000 Leuven, Belgium
    J Chromatogr A 1082:235-9. 2005
    ..4 pmol/min/mg) CYP3A4, respectively...
  13. ncbi request reprint Kinetic study of CYP3A4 activity on verapamil by capillary electrophoresis
    Jie Zhang
    Laboratory of Pharmaceutical Chemistry and Drug Analysis, Faculty of Pharmaceutical Sciences, K U Leuven, Van Evenstraat 4, B 3000 Leuven, Belgium
    J Pharm Biomed Anal 39:612-7. 2005
    ..8+/-2.5 microM and 7.67+/-0.26 pmol/min/pmol (or 983 pmol/min/mg) CYP3A4, respectively...
  14. ncbi request reprint Micellization phenomena of amphiphilic block copolymers based on methoxy poly(ethylene glycol) and either crystalline or amorphous poly(caprolactone-b-lactide)
    Jie Zhang
    Institute of Polymer Science, Zhejiang University, Hang Zhou, 310027 China
    Biomacromolecules 7:2492-500. 2006
    ..A possible mechanism for the cylindrical assembly morphology was discussed...
  15. ncbi request reprint [Mechanism of wenpi decoction delaying progression of chronic renal failure]
    Jie Zhang
    Department of Traditional Chinese Medicine, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China
    Zhongguo Zhong Yao Za Zhi 31:1473-6. 2006
    ..Wenpi decoction is an effective agent for delaying the progression of chronic renal failure...
  16. ncbi request reprint Synergistic inhibitory activity of zoledronate and paclitaxel on bone metastasis in nude mice
    Shun Lu
    Shanghai Lung Cancer Center, Shanghai Chest Hospital, Jiao Tong University, Shanghai, P R China
    Oncol Rep 20:581-7. 2008
    ....
  17. doi request reprint Investigation of mediated oxidation of ascorbic acid by ferrocenemethanol using large-amplitude Fourier transformed ac voltammetry under quasi-reversible electron-transfer conditions at an indium tin oxide electrode
    Benchaporn Lertanantawong
    School of Bioresources and Technology, King Mongkut s University of Technology, Thonburi, Thailand
    Anal Chem 80:6515-25. 2008
    ..The theoretical concepts derived for large-amplitude FT ac voltammetry are believed to be applicable to a wide range of important solution-based mediated electrocatalytic reactions...
  18. doi request reprint Nonredundant function of secretory carrier membrane protein isoforms in dense core vesicle exocytosis
    Haini Liao
    Dept of Cell Biology and Cell and Developmental Biology Program, Univ of Virginia, Charlottesville, VA 22908, USA
    Am J Physiol Cell Physiol 294:C797-809. 2008
    ..Thus, SCAMP-1 and -2 are most closely linked to the final events of exocytosis. Other SCAMPs collaborate in regulating fusion sites, but the roles of individual isoforms appear at least partially distinct...
  19. ncbi request reprint Establishment of a new human glioblastoma multiforme cell line (WJ1) and its partial characterization
    Jing Wang
    Laboratory of Experimental Oncology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, PR China
    Cell Mol Neurobiol 27:831-43. 2007
    ..5) This cell line may provide a useful model in vitro and in vivo in the cellular and molecular studies as well as in testing novel therapies for human glioblastoma multiforme...
  20. ncbi request reprint Abnormal nuclear factor (NF)-kappaB signal pathway and aspirin inhibits tumor necrosis factor alpha-induced NF-kappaB activation in keloid fibroblasts
    Guiying Zhu
    Department of Plastic Surgery, the Second Hospital of Shandong University, Jinan, Shandong Province, People s Republic of China
    Dermatol Surg 33:697-708. 2007
    ..Keloid is characterized with disproportionate extracellular matrix accumulation and fibroblast proliferation. Rel/nuclear factor-kappaB (NF-kappaB) signal transduction pathway may play an important role in keloid pathogenesis...
  21. ncbi request reprint deltaEF1 represses BMP-2-induced differentiation of C2C12 myoblasts into the osteoblast lineage
    Shuang Yang
    Medical College of Nankai University, 94 Weijin Road, Tianjin, 300071, China
    J Biomed Sci 14:663-79. 2007
    ..These results suggest that deltaEF1 acts as a potent inhibitor of BMP-2-induced osteogenesis in vitro, in part, by differentially regulating the AP-1 signaling pathway...
  22. ncbi request reprint Sirtuin inhibition increases the rate of non-homologous end-joining of DNA double strand breaks
    Maria Wojewodzka
    Department of Radiobiology and Health Protection, Institute of Nuclear Chemistry and Technology, Warszawa, Poland
    Acta Biochim Pol 54:63-9. 2007
    ....
  23. ncbi request reprint The phosphothreonine lyase activity of a bacterial type III effector family
    Hongtao Li
    National Institute of Biological Sciences, Beijing, 102206, China
    Science 315:1000-3. 2007
    ..This unexpected enzymatic activity, termed phosphothreonine lyase, appeared specific for MAPKs and was shared by other OspF family members...
  24. ncbi request reprint An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes
    Xiaojun Han
    Pharmaceutical Research Institute, Bristol Myers Squibb Company, 5 Research Parkway, Wallingford, CT 06492, USA
    Bioorg Med Chem Lett 17:2026-30. 2007
    ..Herein we report the synthesis and SAR around the tricyclic core and the anxiolytic activity of an orally dosed exemplary compound 9d (K(i)=8.0 nM) in a mouse canopy model...
  25. ncbi request reprint Distinct patterns of intracerebral hemorrhage-induced alterations in NF-kappaB subunit, iNOS, and COX-2 expression
    Xiurong Zhao
    Department of Neurology, Stroke Program, University of Texas Houston Medical School, Houston, Texas 77030, USA
    J Neurochem 101:652-63. 2007
    ..In summary, NF-kappaB activation occurs within minutes and persists for at least a week in response to ICH. This reaction utilizes different NF-kappaB regulatory subunits and is associated with the expression of selected target genes...
  26. ncbi request reprint Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model
    Qiang Liu
    State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Academia Sinica, Beijing, China
    FASEB J 21:61-73. 2007
    ..The dissected signaling pathway of nicotine-mediated neuroprotection in the present study provides a mechanistic basis for the potential development of drug targets for treating AD...
  27. ncbi request reprint Metabolism of melphalan by rat liver microsomal glutathione S-transferase
    Jie Zhang
    Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, 310031 Hangzhou, China
    Chem Biol Interact 152:101-6. 2005
    ..5-fold with melphalan had a stronger catalytic effect. Thus microsomal GST may play a potential role in the metabolism of melphalan in biological membranes, and in the development of ADR...
  28. ncbi request reprint Scanning electrochemical microscopy (SECM) studies of oxygen transfer across phospholipid monolayers under surface pressure control: comparison of monolayers at air/water and oil/water interfaces
    Susan Cannan
    Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom
    Langmuir 20:701-7. 2004
    ..The results obtained for each interface are compared, and the implications for studies of passive diffusion across cell membranes are discussed...
  29. ncbi request reprint Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors
    Lucio Tentori
    Department of Neuroscience, University of Rome Tor Vergata, I 00133 Rome, Italy
    Int J Oncol 26:415-22. 2005
    ..In conclusion, PARP-1 inhibitor GPI 15427 is efficacious as chemosensitizer for the treatment of tumors located at the CNS site when it is administered by oral route...
  30. ncbi request reprint [A study of the inhibition effect of HIFU and its mechanism of action on the proliferation of human breast cancer cells]
    Xiu Jie Wang
    Key Laboratory of Biotherapy of Human Diseases of Ministry of Education, P R China, West China Hospital, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 35:60-3. 2004
    ..To investigate the killing effect of high intensity focused ultrasound (HIFU) on human tumor cells and study the mechanism of its action...
  31. ncbi request reprint Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis
    Xue Li
    Howard Hughes Medical Institute, School and Department of Medicine, UCSD, 9500 Gilman Drive, Room 345, La Jolla, California 92093 0648, USA
    Nature 426:247-54. 2003
    ....
  32. ncbi request reprint 2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy
    Gene M Dubowchik
    Bristol Myers Squibb Pharmaceutical Research Institute, PO Box 5100, Wallingford, CT 06492 7660, USA
    Bioorg Med Chem Lett 13:3997-4000. 2003
    ..Herein, we report binding SAR as well as anxiolytic activity of an exemplary compound (7a, K(i)=8.6 nM) in a mouse canopy model...
  33. ncbi request reprint Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway
    Jie Zhang
    Lombardi Cancer Center, Georgetown University Medical School, Washington, DC 20057 1469, USA
    Oncogene 22:6289-95. 2003
    ..In summary, we have provided evidence that PTEN-null myeloma cells are stringently dependent on the PI3K/Akt activation for cell survival. These results may provide a basis to treat myeloma patients with PI3K and Akt inhibitors...
  34. ncbi request reprint Effects of transferrin on the growth and proliferation of porcine hepatocytes: a comparison with epidermal growth factor and nicotinamide
    Yulan Liu
    Department of Gastroenterology, People s Hospital, Peking University, Beijing 100044, China
    Chin Med J (Engl) 116:1223-7. 2003
    ..To seek an appropriate culture condition in which porcine hepatocytes can continuously proliferate and express their normal differentiation phenotypes for a longer period of time...
  35. ncbi request reprint A protein in pig spleen similar to immune suppressive protein of stress
    Hong Yan Fu
    Department of Physiology and Pathophysiology, Health Science Center, Peking University, Beijing 100083, China
    Acta Pharmacol Sin 24:593-8. 2003
    ..To purify a protein in pig spleens, which was similar to immune suppressive protein of stress (ISPS), and characterize its properties and functions...
  36. ncbi request reprint Hemoglobin dendrimers: functional protein clusters
    Ronald Kluger
    Davenport Chemical Research Building, Department of Chemistry, University of Toronto, Ontario, Canada M5S 3H6
    J Am Chem Soc 125:6070-1. 2003
    ..The altered oxygen-binding properties are assigned to protein-protein interactions...
  37. ncbi request reprint Function and regulation of Aurora/Ipl1p kinase family in cell division
    Yu Wen Ke
    Laboratory for Cell Dynamics, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China
    Cell Res 13:69-81. 2003
    ..This article highlights the function and regulation of Aurora/Ipl1p family in mitosis and provides potential links between aberrant regulation of Aurora/Ipl1p kinases and pathogenesis of human cancer...
  38. ncbi request reprint The inhibitory effect of BSP-A1/-A2 on protein kinase C and tyrosine protein kinase
    Bingzhi Yu
    Department of Biochemistry, China Medical University, 92, North Second Road, Shenyang, Liaoning Province, 110001, People s Republic of China
    Cell Biochem Funct 21:183-8. 2003
    ..When the PKC and TPK activities are expressed as the logarithm of percentage activity taking the activity in the absence of the BSP-A1/-A2 as 100%, there is a linear relationship between the their activities and the dose of BSP-A1/-A2...
  39. ncbi request reprint [Effect of spinal cord injury on iNOS and Bcl-2 gene expression in spermatogenic cell of the male rat]
    Yong Wei
    Department of Urology, The Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
    Zhonghua Nan Ke Xue 9:28-31, 54. 2003
    ..To investigate the cause of spermatogenic cells decreasing after spinal cord injury...
  40. ncbi request reprint [Autocrine regulation for transforming growth factor-beta 1 by fibroblast in vitro]
    Jie Zhang
    Institute of Cancer, West China Hospital, Sichuan University, Chengdu, Sichuan, P R China 610041
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 16:319-21. 2002
    ..To explore the autocrine regulation for the transforming growth factor-beta 1(TGF-beta 1) by the fibroblasts in vitro...
  41. ncbi request reprint Kinetic evidence that cysteine reacts with dopaminoquinone via reversible adduct formation to yield 5-cysteinyl-dopamine: an important precursor of neuromelanin
    Guy N L Jameson
    Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9 163 AC, A 1060 Vienna, Austria
    Org Biomol Chem 2:777-82. 2004
    ..El-Ayaan, E. Herlinger, R. F. Jameson, and W. Linert, J. Chem. Soc., Dalton Trans., 1997, 2813-2818) and we show how this has important implications concerning the production of neuromelanin...
  42. ncbi request reprint [Comparative research of the donor site wound healing in occlusive and dry environments]
    Jie Zhang
    Department of Plastic Surgery, Third Hospital of Peking University, Beijing, P R China 100083
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 18:152-5. 2004
    ..To compare and research the process of wound healing in occlusive moist environment and dry environment on the skin donor site...
  43. ncbi request reprint Protein kinase A regulates cell cycle progression of mouse fertilized eggs by means of MPF
    Bingzhi Yu
    Department of Biochemical and Molecular Biology, China Medical University, Shenyang, Liaoning, People s Republic of China
    Dev Dyn 232:98-105. 2005
    ..Our results show that PKA, by inhibiting MPF, regulates cell cycle progression of fertilized eggs...
  44. ncbi request reprint Nitric oxide synthase inhibition prevents neuronal death in the developing visual cortex
    Yueting Zhang
    Laboratory of Visual Information Processing, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing 100101, People s Republic of China
    Eur J Neurosci 20:2251-9. 2004
    ..NOS inhibition largely rescued neurons from undergoing apoptosis, indicating that NO may serve as a signal triggering apoptosis and play a role in the maturation of the visual cortex...
  45. ncbi request reprint Arginine 391 in subunit I of the cytochrome bd quinol oxidase from Escherichia coli stabilizes the reduced form of the hemes and is essential for quinol oxidase activity
    Jie Zhang
    Department of Biochemistry, University of Illinois, Urbana, Illinois 61801, USA
    J Biol Chem 279:53980-7. 2004
    ..The fact that the midpoint potentials of heme d and heme b(595) are also significantly lowered in the R391A mutant is consistent with these hemes being physically close together on the periplasmic side of the membrane...
  46. pmc Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa
    Susan P Yates
    Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada N1G 2W1
    Biochem J 385:667-75. 2005
    ..The present study provides insight into the important features required for inhibitors that mimic NAD+ and their binding to the mono-ADPRT family of toxins...
  47. ncbi request reprint [Activity of toremifene plus mitomycin, vindesin and cisplatin regimen in unresectable non-small cell lung cancer]
    Cai Cun Zhou
    Department of Oncology, Shanghai Pulmonary Hospital, Shanghai 200433, China
    Zhonghua Jie He He Hu Xi Za Zhi 27:546-8. 2004
    ..To investigate the activity and clinical efficacy of toremifene plus mitomycin, vindesin and cisplatin regimen (MVP) in non-small cell lung cancer (NSCLC)...
  48. ncbi request reprint The effects of meso-2,3-dimercaptosuccinic acid and oligomeric procyanidins on acute lead neurotoxicity in rat hippocampus
    Jie Zhang
    Laboratory of Visual Information Processing, Center for Brain and Cognitive Sciences, Institute of Biophysics, Academia Sinica, Beijing 100101 China
    Free Radic Biol Med 37:1037-50. 2004
    ..At the same time, a reasonable deduction can also be made that the complex of OPC-Pb(2+) prevents or at least weakens the neurotoxicity of Pb(2+). Whether this complex displays toxicity over a long time span should be studied further...
  49. ncbi request reprint TTK kinase is essential for the centrosomal localization of TACC2
    Zhen Dou
    Hefei National Laboratory for Physical Sciences at Micro scale, Hefei 230027, China
    FEBS Lett 572:51-6. 2004
    ..The inter-relationship between TTK and TACC2 established here provides new avenue to study centrosome and spindle dynamics underlying cell divisional control...
  50. ncbi request reprint Potential involvement of leptin in carcinogenesis of hepatocellular carcinoma
    Xiu Jie Wang
    Division of Experimental Oncology, Key Laboratory of Biotherapy of Human Diseases of Ministry of Education, China, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    World J Gastroenterol 10:2478-81. 2004
    ..To investigate the potential involvement of leptin in carcinogenesis of hepatocellular carcinoma (HCC) and to elucidate the etiology, carcinogenesis and progress of HCC...
  51. ncbi request reprint [Visualizing living fibroblast on co-cultured denture base resin by green fluorescent protein marker introduced into the cell]
    Jin Liu
    Lab of Transplant Engineering and Transplant Immunology, West China Hospital, Sichuan University, Chengdu 610041, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 21:355-8. 2004
    ..And it was suggested that imaging of living cells co-cultured with biomaterial is helpful to understanding biocompatibility of materials more accurately...
  52. ncbi request reprint Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells
    Shu Lan Yuan
    Key Laboratory of Biotherapy of Human Diseases, Ministry of Education of China and Cancer Center, West China Hospital, 37 Guo Xue Xiang, Chengdu 610041, Sichuan Province, China
    World J Gastroenterol 10:2024-8. 2004
    ..To evaluate the effects of tanshinone II-A on inducing growth inhibition and apoptosis of human hepatocellular carcinoma (HCC) cells...
  53. ncbi request reprint [The expression of API2-MALT1 fusion gene and its influence on the cellular apoptosis and proliferation in gastrointestinal MALT lymphoma]
    Wen Xiu Yang
    Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 35:172-5. 2004
    ..To investigate the expression of API2-MALT1 fusion gene mRNA and its effect on protein of API2, Caspase3 and Ki67 in gastrointestinal MALT lymphoma (Extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue)...
  54. ncbi request reprint Thrombin stimulation of vascular adhesion molecule-1 in endothelial cells is mediated by protein kinase C (PKC)-delta-NF-kappa B and PKC-zeta-GATA signaling pathways
    Takashi Minami
    Department of Molecular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 278:6976-84. 2003
    ..Taken together, these data suggest that the endothelial cell-specific effect of thrombin on VCAM-1 expression involves the coordinate activity of PKC-delta-NF-kappaB and PKC-zeta-GATA signaling pathways...