Kunio Yui

Summary

Country: Japan

Publications

  1. ncbi request reprint Eicosanoids Derived From Arachidonic Acid and Their Family Prostaglandins and Cyclooxygenase in Psychiatric Disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University Graduate School of Education Rokurokusocho 13 22, Ashiya 659 8511, Hyogo, Japan
    Curr Neuropharmacol 13:776-85. 2015
  2. doi request reprint Down-regulation of a signaling mediator in association with lowered plasma arachidonic acid levels in individuals with autism spectrum disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University, 13 22 Rokurokusocho, Ashiya, 659 8511 Hyogo, Japan Electronic address
    Neurosci Lett 610:223-8. 2016
  3. doi request reprint Increased ω-3 polyunsaturated fatty acid/arachidonic acid ratios and upregulation of signaling mediator in individuals with autism spectrum disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University, 13 22 Rokurokusocho, Ashiya 659 8511, Hyogo, Japan Electronic address
    Life Sci 145:205-12. 2016
  4. ncbi request reprint Mitochondrial Dysfunction and Its Relationship with mTOR Signaling and Oxidative Damage in Autism Spectrum Disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University Graduate School of Education, Ashiya 659 8511, Japan
    Mini Rev Med Chem 15:373-89. 2015
  5. doi request reprint Effects of large doses of arachidonic acid added to docosahexaenoic acid on social impairment in individuals with autism spectrum disorders: a double-blind, placebo-controlled, randomized trial
    Kunio Yui
    Research Institute of Progressive Developmental Disorders, Ashiya University Graduate School of Education, Ashiya, Japan
    J Clin Psychopharmacol 32:200-6. 2012
  6. ncbi request reprint [Therapeutic effects of larger doses of arachidonic acid added to DHA on social impairment and its relation to alterations of polyunsaturated fatty acids in individuals with autism spectrum disorders]
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, 13 22 Rokurokuso machi, Ashiya 659 8511, Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 31:117-24. 2011
  7. ncbi request reprint [Useful pharmacologic treatment in impaired social interaction in autism spectrum disorders]
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Graduate School of Education, Ashiya University
    Seishin Shinkeigaku Zasshi 114:934-40. 2012

Detail Information

Publications7

  1. ncbi request reprint Eicosanoids Derived From Arachidonic Acid and Their Family Prostaglandins and Cyclooxygenase in Psychiatric Disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University Graduate School of Education Rokurokusocho 13 22, Ashiya 659 8511, Hyogo, Japan
    Curr Neuropharmacol 13:776-85. 2015
    ..COX-2 is typically induced by inflammatory stimuli in the majority of tissues, and the only isoform responsible for propagating the inflammatory response. Thus, COX-2 inhibitors considered as the best target for Alzheimer's disease. ..
  2. doi request reprint Down-regulation of a signaling mediator in association with lowered plasma arachidonic acid levels in individuals with autism spectrum disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University, 13 22 Rokurokusocho, Ashiya, 659 8511 Hyogo, Japan Electronic address
    Neurosci Lett 610:223-8. 2016
    ..These findings suggest that reduced plasma AA levels may downregulate Cp. ..
  3. doi request reprint Increased ω-3 polyunsaturated fatty acid/arachidonic acid ratios and upregulation of signaling mediator in individuals with autism spectrum disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University, 13 22 Rokurokusocho, Ashiya 659 8511, Hyogo, Japan Electronic address
    Life Sci 145:205-12. 2016
    ..The investigation of links between the ratio of omega-3/omega-6 PUFAs and neuronal signaling is a research priority in autism spectrum disorders (ASD)...
  4. ncbi request reprint Mitochondrial Dysfunction and Its Relationship with mTOR Signaling and Oxidative Damage in Autism Spectrum Disorders
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Ashiya University Graduate School of Education, Ashiya 659 8511, Japan
    Mini Rev Med Chem 15:373-89. 2015
    ..Finally, a decrease in total antioxidant capacity may account for ASD children who show core social and behavioral impairments without neurological and somatic symptoms. ..
  5. doi request reprint Effects of large doses of arachidonic acid added to docosahexaenoic acid on social impairment in individuals with autism spectrum disorders: a double-blind, placebo-controlled, randomized trial
    Kunio Yui
    Research Institute of Progressive Developmental Disorders, Ashiya University Graduate School of Education, Ashiya, Japan
    J Clin Psychopharmacol 32:200-6. 2012
    ..This preliminary study suggests that supplementation with larger ARA doses added to DHA improves impaired social interaction in individuals with autism spectrum disorder by up-regulating signal transduction...
  6. ncbi request reprint [Therapeutic effects of larger doses of arachidonic acid added to DHA on social impairment and its relation to alterations of polyunsaturated fatty acids in individuals with autism spectrum disorders]
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, 13 22 Rokurokuso machi, Ashiya 659 8511, Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 31:117-24. 2011
    ..The present clinical trials suggest that supplementation with larger ARA doses added to DHA improves social impairment in individuals with ASD via ARA-induced upregulation of neuronal functioning...
  7. ncbi request reprint [Useful pharmacologic treatment in impaired social interaction in autism spectrum disorders]
    Kunio Yui
    Research Institute of Pervasive Developmental Disorders, Graduate School of Education, Ashiya University
    Seishin Shinkeigaku Zasshi 114:934-40. 2012
    ..Environmental chemicals can affect the development of the brain. Further studies will be required to address the effect of environmental chemicals...