Research Topics
Genomes and Genes | Masanari UmemuraSummaryAffiliation: Yokohama City University Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Implication of base heart rate in autonomic nervous function, blood pressure and health-related QOLYasuko Okano
Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama City, Japan
Clin Exp Hypertens 27:169-78. 2005..Using multivariate analysis, HRo is related to LF/HF, body mass index, and the score of social functioning (HRQOL). HRo may be a useful indicator for assessing sympathetic nervous activity and HRQOL in normotensive healthy subjects...
Ambulatory blood pressure variability is increased in diabetic hypertensivesMotoko Ozawa
Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
Clin Exp Hypertens 30:213-24. 2008..Taken together, these results demonstrate that BP variability is increased in diabetic hypertensives. Furthermore, it is possible that an elevation of fasting blood glucose may contribute to the enhanced BP variability in hypertensives...- Acute renal failure due to cholesterol crystal embolism treated with LDL apheresis followed by corticosteroid and candesartanKouichi Tamura
Second Department of Medicine, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
Clin Exp Nephrol 7:67-71. 2003..Therefore, a combination therapy of LDL-A, low-dose corticosteroid, and an ARB is a possible treatment for CCE, although the possibility of spontaneous recovery of renal function cannot be eliminated for this patient... - Ambulatory blood pressure and heart rate in hypertensives with renal failure: comparison between diabetic nephropathy and non-diabetic glomerulopathyKouichi Tamura
Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
Clin Exp Hypertens 30:33-43. 2008.... - Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expressionKouichi Tamura
Department of Medicine II, Yokohama City University School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
Mol Cell Endocrinol 224:11-20. 2004..These results suggest that LXRalpha plays an important role in the cAMP-mediated regulation of human renin gene transcription by binding to CNRE... - The role of angiotensin AT1 receptor-associated protein in renin-angiotensin system regulation and functionKouichi Tamura
Department of Cardiorenal Medicine, Yokohama City University School of Medicine, 3 9 Fukuura, Yokohama, Japan
Curr Hypertens Rep 9:121-7. 2007..We would expect ATRAP to become a new therapeutic target molecule to treat and prevent cardiovascular remodeling in hypertension... - A possible relationship of nocturnal blood pressure variability with coronary artery disease in diabetic nephropathyKouichi Tamura
Department of Medicine II, Yokohama City University School of Medicine, Yokohama, Japan
Clin Exp Hypertens 29:31-42. 2007..Elevated short-term BP variability combined with relative sympathetic prevalence during the night might represent an important risk factor for cardiovascular events in the diabetic population... - Identification of NPC2 protein as interaction molecule with C2 domain of human Nedd4LNaomi Araki
Yokohama City University Graduate School of Medicine, Department of Medical Science and Cardio renal Medicine, Yokohama City, Kanagawa ken 236 0004, Japan
Biochem Biophys Res Commun 388:290-6. 2009..NPC2 might regulate sodium reabsorption in the terminal nephron by interacting with ENaC-Nedd4L system... - Expression, transcription, and possible antagonistic interaction of the human Nedd4L gene variant: implications for essential hypertensionNaomi Araki
Department of Medical Science and Cardio renal Medicine, Yokohama City University Graduate School of Medicine, Kanagawa Ken, Japan
Hypertension 51:773-7. 2008..Such interactions might abnormally increase sodium reabsorption. Taken together, our analyses suggest that the human Nedd4L gene, especially the evolutionarily new isoform I, is a candidate gene for hypertension... - The novel angiotensin II type 1 receptor (AT1R)-associated protein ATRAP downregulates AT1R and ameliorates cardiomyocyte hypertrophyYutaka Tanaka
Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
FEBS Lett 579:1579-86. 2005..These results indicate that ATRAP significantly promotes downregulation of the AT1R and further attenuates certain Ang II-mediated hypertrophic responses in cardiomyocytes... - Transcriptional diversity and expression of NEDD4L gene in distal nephronMasanari Umemura
Department of Internal Medicine and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
Biochem Biophys Res Commun 339:1129-37. 2006..This response was impaired in genetically sodium-sensitive animals. These findings suggested that Nedd4L gene products were involved in the development of salt-sensitive hypertension... - Analysis of factors that affect short-term blood pressure variability in patients with chronic renal failureMasashi Sakai
Department of Medicine II, Yokohama City University School of Medicine, Yokohama, Japan
Clin Exp Hypertens 27:139-47. 2005..Furthermore, sympathetic nerve overactivity may be involved in cardiovascular complications in CRF patients through the increase in nighttime systolic BP variability... - Relationships between diurnal blood pressure variation, physical activity, and health-related QOLYasuko Okano
Second Department of Internal Medicine, Yokohama City University School of Medicine, Yokohama City, Japan
Clin Exp Hypertens 26:145-55. 2004..05, p < 0.05, respectively). In conclusion, physical activity is associated with the nocturnal dip in blood pressure. Moreover, physical activity correlates with some of the factors of HRQOL...