Research Topics
| Yasuko YogiSummaryCountry: Japan Publications
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Detail Information
Publications
[History for animal model of Hansen's disease and characteristics of leprosy in hypertensive nude rat]Yasuko Yogi
Leprosy Research Center, National Institute of Infectious Diseases, 1 6 7 502 Hirose, Sayama, Saitama 350 1319, Japan
Nihon Hansenbyo Gakkai Zasshi 77:197-204. 2008..Also this hypertensive nude rat strain produce high level of IL-10. Therefore, congenic hypertensive nude rat may be useful for an animal model to leprosy...
[Susceptibility to Mycobacterium leprae of congenic hypertensive nude rat (SHR/NCrj-rnu) and production of cytokine from the resident peritoneal macrophages]Yasuko Yogi
Leprosy Research Center, National Institute of Infectious Diseases, 4-2-1 Aobacho, Higasimurayama-shi, Tokyo 189-0002, Japan
Nihon Hansenbyo Gakkai Zasshi 71:39-45. 2002..We also examined the cytokine production. The resident peritoneal macrophages of SHR/NCrj-rnu rats produced IL-1 alpha, IL-6, IL-10 and TNF alpha, whereas those of F344/NJcl-rnu rats produced only TNF alpha...
Effect of hsp65 DNA vaccination carrying immunostimulatory DNA sequences (CpG motifs) against Mycobacterium leprae multiplication in miceHiroko Nomaguchi
Leprosy Research Center, National Institute of Infectious Diseases, 4-2-1-Aobacho, Higashimurayama, Tokyo, Japan
Int J Lepr Other Mycobact Dis 70:182-90. 2002..leprae. These results suggest that a DNA containing M. leprae-derived hsp65 and immunostimulatory sequences might be a potent vaccine candidate against M. leprae infection...
Prevention of diabetes in non-obese diabetic mice by a single immunization with Mycobacterium lepraeHiroko Nomaguchi
Leprosy Research Center, National Institute of Infectious Diseases, 4 2 1 Aobacho, Higashimurayama shi, Tokyo 189 0002, Japan
Nihon Hansenbyo Gakkai Zasshi 71:31-8. 2002..leprae immunized cases in which the IDDM incidence was prevented, and both control and M. leprae immunized groups produced IFN-gamma and IL-10 by stimulation with hsp65...
Recombinant Mycobacterium leprae protein associated with entry into mammalian cells of respiratory and skin componentsNaoya Sato
Department of Dermatology, Graduate School of Medical Science, Kitasato University, 1 15 1 Kitasato, Sagamihara, Kanagawa 228 8555, Japan
J Dermatol Sci 46:101-10. 2007..The M. leprae genome contains mce1A gene, which encodes a putative mammalian cell entry protein. However, to date, there have been no functional analyses of the M. leprae mce1A gene product...
