Research Topics
| R KatohSummaryAffiliation: Yamanashi Medical University Country: Japan Publications
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Detail Information
Publications
Angiogenesis in endocrine glands: special reference to the expression of vascular endothelial growth factorRyohei Katoh
Department of Pathology, Yamanashi Medical University, Yamanashi 409 3898, Japan
Microsc Res Tech 60:181-5. 2003..In this article, recent studies on angiogenic factors, especially on expression of VEGF, are reviewed in the field of endocrine systems...- Accumulated basement membrane material in hyalinizing trabecular tumors of the thyroidR Katoh
Department of Pathology, Yamanashi Medical University, Tamaho, Japan
Mod Pathol 12:1057-61. 1999..From the findings, electron microscopic features of accumulated BM material are very characteristic in hyalinizing trabecular adenomas and can be discernible from other histologic types of BM-producing tumors... - Thyroid transcription factor-1 in normal, hyperplastic, and neoplastic follicular thyroid cells examined by immunohistochemistry and nonradioactive in situ hybridizationR Katoh
Department of Pathology, Yamanashi Medical University School of Medicine, Tamaho, Japan
Mod Pathol 13:570-6. 2000..In conclusion, the investigation of TTF-1 provides useful information on the functional activities and/or differentiation of thyroid tumors and may lead to an increase in our understanding of the biologic nature of thyroid tumors... - Expression of thyroid transcription factor-1 (TTF-1) in human C cells and medullary thyroid carcinomasR Katoh
Department of Pathology, Yamanashi Medical University School of Medicine, Japan
Hum Pathol 31:386-93. 2000..Therefore, TTF-1 expression can be a functional marker not only for follicular cells and follicular cell tumors but also for C cells and medullary C cell carcinomas... - Thyrotropin prevents apoptosis by promoting cell adhesion and cell cycle progression in FRTL-5 cellsX Li
Department of Pathology, Yamanashi Medical University, Nakakoma, Japan
Endocrinology 140:5962-70. 1999..We concluded that in addition to regulating growth and differentiation, TSH may function as a survival factor in thyroid cells by preventing anchorage-dependent apoptosis in FRTL-5 cells partly via the cAMP pathway... - Thyroid stimulating hormone downregulates vascular endothelial growth factor expression in FRTL-5 cellsE Miyagi
Department of Pathology, Yamanashi Medical University, Nakakomagun, Japan
Thyroid 11:539-43. 2001..This observation is contrary to previously published results using the thyroid follicular culture system. Our results suggest that the direct effect of TSH/cAMP is to inhibit the VEGF synthesis in monolayer cells... 
Increased expression of the sodium/iodide symporter in papillary thyroid carcinomasT Saito
Third Department of Internal Medicine, Yamanashi Medical University, Tamaho, Yamanashi 409 38, Japan
J Clin Invest 101:1296-300. 1998..Although considerable patient-to-patient variation was observed, our results indicate that NIS mRNA is elevated, and its protein tends to be more abundant, in a subset of papillary thyroid carcinomas than in normal thyroid tissue...- Incidentally detected liver metastasis of well-differentiated follicular carcinoma of the thyroid, mimicking ectopic thyroidT Kondo
Department of Pathology, Yamanashi Medical University, Tamaho, Japan
Pathol Int 50:509-13. 2000..Subsequent whole-body examination failed to find other metastases. It was determined that the liver tumor was metastasized from well-differentiated follicular carcinoma of the thyroid... - Immunohistochemical estimations of growth activity to predict biological behavior of pheochromocytomasS Nagura
Department of Pathology, Yamanashi Medical University, Tamaho, Japan
Mod Pathol 12:1107-11. 1999..Especially, it is important to note that a high MIB-1-positive cell rate (>2%) is highly suggestive of malignancy... - mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathwayH Kato
Department of Molecular Signaling, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Yamanashi 409 3898, Japan
Cell Death Differ 19:310-20. 2012..These results disclosed that, under ER stress conditions, mTORC1 causes apoptosis through suppression of Akt and consequent induction of the IRE1-JNK pathway... - Autonomic nerve tumour with skeinoid fibres: ultrastructure of skeinoid fibres examined by quick-freezing and deep-etching methodA Hemmi
Department of Pathology and Anatomy, Yamanashi Medical University, Tamaho, Japan
Virchows Arch 434:267-76. 1999..We conclude that SFs are formed by decoration of the granular deposits along pre-existing intercellular meshwork structures... - Endocervical adenocarcinomas associated with lobular endocervical glandular hyperplasia: a report of four cases with histochemical and immunohistochemical analysesTetsuo Kondo
Department of Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
Mod Pathol 18:1199-210. 2005..Histopathological features of the present cases suggest that some endocervical adenocarcinomas may originate from lobular endocervical glandular hyperplasia... - Application of microscopic Forster resonance energy transfer to cytological diagnosis of the thyroid tumorsShin Ichi Murata
University of Yamanashi, Interdisciplinary Graduate School of Medicine and Engineering, Department of Pathology, Yamanashi, Japan
J Biomed Opt 10:034008. 2005..c) 2005 Society of Photo-Optical Instrumentation Engineers... - p16INK4a overexpression independent of human papillomavirus infection in lobular endocervical glandular hyperplasiaAkihiko Hashi
Department of Obstetrics and Gynecology, and Clinical Laboratory, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
Int J Gynecol Pathol 25:187-94. 2006..Overall, p16INK4a overexpression was seen in 87.5% of the cases (21/24). HPV DNA was not detected in any of the 24 LEGH cases. These results suggest that p16INK4a overexpression is independent of HPV infection in LEGH... - Lobular endocervical glandular hyperplasia as a presumed precursor of cervical adenocarcinoma independent of human papillomavirus infectionMasatoshi Nara
Department of Obstetrics and Gynecology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409 3898, Japan
Gynecol Oncol 106:289-98. 2007..The aim of this study was to investigate differences in the process of carcinogenesis between adenocarcinoma coexistent with LEGH and conventional adenocarcinoma. And we intend to describe appropriate treatment plans for LEGH in this study... - Conservation and alteration of chromosome territory arrangements in thyroid carcinoma cell nucleiShin Ichi Murata
Department of Pathology, Saitama Medical University International Medical Center, Saitama, Japan
Thyroid 17:489-96. 2007..These findings indicate that alteration of CT positioning could be related to DNA amplification and, morphologically, may explain the nuclear atypia that accompanies the abnormal chromatin feature... - Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approachMarco Volante
Department of Clinical and Biological Sciences at San Luigi Hospital, University of Turin, Turin, Italy
Am J Surg Pathol 31:1256-64. 2007..An algorithmic approach was devised for practical use in the diagnosis of this tumor... 
Intranuclear cytoplasmic inclusion is a significant diagnostic feature for the differentiation of lobular endocervical glandular hyperplasia from minimal deviation adenocarcinoma of the cervixAkihiko Hashi
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Yamanashi, Japan
Diagn Cytopathol 36:535-44. 2008..The presence of an INCI is a good parameter for the diagnosis of LEGH. Cytology is an effective aid in the differentiation of LEGH from MDA...- Absence of human papillomavirus infection in minimal deviation adenocarcinoma and lobular endocervical glandular hyperplasiaJia-Ying Xu
Department of Obstetrics and Gynecology, University of Yamanashi, Yamanashi 409-3898, Japan
Int J Gynecol Pathol 24:296-302. 2005..However, no HPV DNA was detected in any of the 10 cases of LEGH or in the 3 cases of MDA. These results suggest that MDA and LEGH are probably not related to HPV infection... - Detection of underlying characteristics of nuclear chromatin patterns of thyroid tumor cells using texture and factor analysesShin Ichi Murata
Department of Pathology, University of Yamanashi School of Medicine, Yamanashi, Japan
Cytometry 49:91-5. 2002..In the present report, we investigated how to detect underlying chromatin characteristics of benign and malignant thyroid tumor cells by means of texture and factor analyses... - Morphological abstraction of thyroid tumor cell nuclei using morphometry with factor analysisShin Ichi Murata
Department of Pathology, University of Yamanashi School of Medicine, Nakakoma gun, Yamanashi, Japan
Microsc Res Tech 61:457-62. 2003..Morphological abstraction by morphometry with factor analysis may provide a practical approach to the detection of the underlying characteristics of nuclear morphology in aspiration biopsy cytology... - Thyroid gland: international case conferenceKennichi Kakudo
Deparmtent of Pathology, Wakayama Medical University, Kimiidera, Wakayama, Japan
Endocr Pathol 13:131-4. 2002..In this article, we present two of the cases, attempt to explain the reason for disagreement in their diagnoses, and propose what should be done to obtain better consensus in diagnosis... - Spatial distribution analysis of AT- and GC-rich regions in nuclei using corrected fluorescence resonance energy transferShin Ichi Murata
Department of Pathology, University of Yamanashi School of Medicine, 1110 Shimokato, Tamaho cho Nakakoma gun, Yamanishi, Japan 409 3898
J Histochem Cytochem 51:951-8. 2003..Using the corrected FRET (cFRET) technique, we were able to detect early DNA separation stages in late interphase nuclei... - Expression of thyroid transcription factor-1 in normal and neoplastic lung tissuesNobuki Nakamura
Department of Pathology, Yamanashi Medical University, Yamanashi, Japan
Mod Pathol 15:1058-67. 2002..Thyroid transcription factor-1 expression associates with histologic types and/or differentiation of lung cancers and can be a valuable marker for the better understanding of their biological nature and pathological behavior... - Observer variation of encapsulated follicular lesions of the thyroid glandMitsuyoshi Hirokawa
Department of Pathology, University of Tokushima School of Medicine, Japan
Am J Surg Pathol 26:1508-14. 2002..To reduce observer variation of encapsulated follicular lesions, it will be necessary to provide more explicit criteria for diagnosis... - Estimation of prognoses for cervical intraepithelial neoplasia 2 by p16INK4a immunoexpression and high-risk HPV in situ hybridization signal typesMakiko Omori
Department of Obstetrics and Gynecology, University of Yamanashi, Yamanashi, Japan
Am J Clin Pathol 128:208-17. 2007..CIN 2 cases with moderate to strong immunoexpression of p16INK4a and a high-risk HPV punctate signal should be treated because of the great risk of progression... - Mutation of ras oncogene in di-isopropanolnitrosamine-induced rat thyroid carcinogenesisYoshihiko Kobayashi
Fuji Biomedix Co, Ltd. Kobuchizawa Laboratories 10221, Kobuchizawa-cho, Kitakoma-gun, Yamanashi-ken, 408-0044, Japan
Virchows Arch 441:289-95. 2002..In conclusion, K- ras mutation plays an important role in DIPN-induced rat thyroid tumorigenesis, possibly regarded as an early event in the tumorigenic process... - Enhanced B-Raf protein expression is independent of V600E mutant status in thyroid carcinomasTetsuo Kondo
Department of Pathology, University of Yamanashi, Chuo, Yamanashi 409 3898, Japan
Hum Pathol 38:1810-8. 2007.... - Histopathology of the thyroid in amiodarone-induced hypothyroidismTadao Nakazawa
Department of Human Pathology, University of Yamanashi Interdisciplinary Graduate School of Medicine and Engineering, Yamanashi, Japan
Pathol Int 58:55-8. 2008..This is the first report on the histopathological findings of thyroid tissue from a patient with amiodarone-induced hypothyroidism... - Clinical impact of preoperative screening for gastric mucin secretion in cervical discharge by HIK1083-labeled latex agglutination testMakiko Omori
Obstetrics and Gynecology, National University Corporation University of Yamanashi, Yamanashi, Japan
Am J Clin Pathol 130:585-94. 2008..In 2 cases of LEGH, adenocarcinoma in situ was identified. Screening of gastric mucin in cervical discharge may facilitate preoperative detection of some early cervical adenocarcinoma... - TGF-beta type I receptor kinase inhibitor down-regulates rheumatoid synoviocytes and prevents the arthritis induced by type II collagen antibodyMichitomo Sakuma
Department of Immunology, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409 3898, Japan
Int Immunol 19:117-26. 2007..The blockade of TGF-beta signaling may thus become an additional strategy for the treatment of RA... - Mixed papillary adenocarcinoma and transitional cell carcinoma of the uterine cervixShin Ichi Murata
Department of Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Japan
Pathol Int 54:63-6. 2004..These findings indicate that the TCC component had the cellular character of AC rather than that of TCC or squamous cell carcinomas. This is thought to be the first report of a MAcTcc of the uterine cervix... - Unusual cytologic findings in low grade papillary transitional cell carcinomaShin Ichi Murata
Department of Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Nakakoma gun, Yamanashi, Japan
Acta Cytol 48:492-6. 2004..To describe cases of low grade papillary transitional cell carcinoma (LG-pTCC) with a low nuclear cytoplasmic (N/C) ratio and unusual cytologic patterns with many isolated, single neoplastic cells... - Application of cryotechniques with freeze-substitution for the immunohistochemical demonstration of intranuclear pCREB and chromosome territoryNobuhiko Ohno
Dept. of Anatomy, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 1110 Shimokato, Tamaho, Yamanashi 409-3898, Japan
J Histochem Cytochem 53:55-62. 2005..Because the reduction of routine pretreatments in the present study might reveal more native morphology, the CrT-FS method would be a useful technique for intranuclear immunostaining and FISH... - [Development of severe aplastic anemia in a girl with Hashimoto's thyroiditis and papillary thyroid carcinoma]Hideaki Yagasaki
Department of Pediatrics, University of Yamanashi School of Medicine
Rinsho Ketsueki 44:328-33. 2003.... - Stromal elastosis in papillary thyroid carcinomasTetsuo Kondo
Department of Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Japan
Hum Pathol 36:474-9. 2005..It is, therefore, reasonable to propose that stromal elastosis is an ancillary feature in the histopathological diagnosis of PTCs... - [Hormone production and secretion in thyroid tumors]Ryohei Katoh
Department of Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi
Nippon Rinsho 62:929-33. 2004..In recent years, evidence has been accumulating for the existence of a tumor group with traits of both follicular and medullary carcinoma, designated as mixed follicular and medullary carcinoma... - RET gene rearrangements (RET/PTC1 and RET/PTC3) in papillary thyroid carcinomas from an iodine-rich country (Japan)Tadao Nakazawa
Department of Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan
Cancer 104:943-51. 2005..Therefore, the current results raise questions regarding the belief that the frequency of RET/PTC differs geographically and is especially low in Japan... - Mucinous carcinoma (poorly differentiated carcinoma with extensive extracellular mucin deposition) of the thyroid: a case report with immunohistochemical studiesTetsuo Kondo
Department of Pathology, University of Yamanashi, Yamanashi, Japan
Hum Pathol 36:698-701. 2005..The patient died of multiple metastases 4 years after the initial operation... - Expression of human pendrin in diseased thyroidsTetsuo Kondo
Department of Pathology, Yamanashi Medical University School of Medicine, Japan
J Histochem Cytochem 51:167-73. 2003.... - Expression of aquaporin 3 (AQP3) in normal and neoplastic lung tissuesYa Lan Liu
Department of Pathology, University of Yamanashi Interdisciplinary Graduate School of Medicine and Engineering, Yamanashi 409 3898, Japan
Hum Pathol 38:171-8. 2007....