Research Topics
Species | Shoichi HazamaSummaryAffiliation: Yamaguchi University Country: Japan Publications
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Detail Information
Publications
Efficacy of orally administered superfine dispersed lentinan (beta-1,3-glucan) for the treatment of advanced colorectal cancerShoichi Hazama
Department of Surgery II, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755 8505, Japan
Anticancer Res 29:2611-7. 2009..To investigate the safety and effectiveness of SDL, a multi center clinical study in patients with advanced colorectal cancer was conducted...
Improvement of QOL and prognosis by treatment of superfine dispersed lentinan in patients with advanced gastric cancerShigefumi Yoshino
Department of Surgery II, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan
Hepatogastroenterology 57:172-7. 2010..Recently, superfine dispersed lentinan--an oral formulation--has become clinically available. In order to evaluate the efficacy of superfine dispersed lentinan, was conducted multicenter clinical study...
Suppressive effects of cyclophosphamide and gemcitabine on regulatory T-cell induction in vitroShin Kan
Department of Digestive Surgery and Surgical Oncology, Yamaguchi University Graduate School of Medicine, 1 1 1 Minami kogushi, Ube City, Yamaguchi Prefecture, 755 8505, Japan
Anticancer Res 32:5363-9. 2012..Inhibition of CD4(+)FOXP3(+) regulatory T-cell (Treg) activity may be important for successful cancer immunotherapy. We investigated the suppressive effects of several chemotherapeutic agents on Treg induction in vitro...
Impact of chemotherapy for colorectal cancer on regulatory T-cells and tumor immunityKazunari Maeda
Department of Digestive Surgery and Surgical Oncology, Yamaguchi University Graduate School of Medicine, 1 1 1 Minamikogushi, Ube City, Yamaguchi Prefecture 755 8505, Japan
Anticancer Res 31:4569-74. 2011..The purpose of the present study was to determine how oxaliplatin plus infusional 5-fluorouracil and leucovorin (FOLFOX) and irinotecan plus infusional 5-fluorouracil and leucovorin (FOLFIRI) affect Tregs and other immune effectors...
Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1*28 polymorphismShoichi Hazama
Department of Digestive Surgery and Surgical Oncology Surgery II, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan
Cancer Sci 101:722-7. 2010..The gene polymorphism should be considered when determining the precise recommended doses to be administered in phase I studies...
The importance of evaluation of DNA amplificability in KRAS mutation testing with dideoxy sequencing using formalin-fixed and paraffin-embedded colorectal cancer tissuesNaoko Okayama
Division of Laboratory, Yamaguchi University Hospital, Ube, Yamaguchi, Japan
Jpn J Clin Oncol 41:165-71. 2011..We evaluated DNA amplificability to achieve a 100% success rate in KRAS mutation testing with dideoxy sequencing using formalin-fixed and paraffin-embedded colorectal cancer tissue samples obtained from a recent clinical trial...
