Research Topics
| M TominagaSummaryAffiliation: Yamagata University Country: Japan Publications
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Detail Information
Publications
Japanese standard reference material JDS Lot 2 for haemoglobin A1c. II: Present state of standardization of haemoglobin A1c in Japan using the new reference material in routine clinical assaysMakoto Tominaga
Department of Laboratory Medicine, Yamagata University School of Medicine, 2 2 2 Iida nishi, Yamagata 990 9585, Japan
Ann Clin Biochem 42:47-50. 2005..Therefore, there should be no difference in the measured values no matter which calibrators are used. The Committee conducted a domestic survey in order to confirm this relationship...
Japanese standard reference material for JDS Lot 2 haemoglobin A1c. I: Comparison of Japan Diabetes Society-assigned values to those obtained by the Japanese and USA domestic standardization programmes and by the International Federation of Clinical ChemiMakoto Tominaga
Department of Laboratory Medicine, Yamagata University School of Medicine, 2 2 2 Iida nishi, Yamagata 990 9585, Japan
Ann Clin Biochem 42:41-6. 2005....
Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes StudyM Tominaga
Department of Laboratory Medicine, Yamagata University School of Medicine, Japan
Diabetes Care 22:920-4. 1999..To determine whether the new category of impaired fasting glucose (IFG) recently proposed by the Expert Committee of the American Diabetes Association is a risk factor for cardiovascular disease...
Insulin activates p38 mitogen-activated protein (MAP) kinase via a MAP kinase kinase (MKK) 3/MKK 6 pathway in vascular smooth muscle cellsM Igarashi
Third Department of Internal Medicine, Yamagata University School of Medicine, Japan
Eur J Clin Invest 30:668-77. 2000..In this study, we investigated the effect of insulin on p38 mitogen-activated protein (MAP) kinase activation in cultured rat vascular smooth muscle cells (VSMC)...
Characterization of platelet-derived growth factor-induced p38 mitogen-activated protein kinase activation in vascular smooth muscle cellsH Yamaguchi
Third Department of Internal Medicine, Yamagata University School of Medicine, Yamagata, Japan
Eur J Clin Invest 31:672-80. 2001....
Candesartan inhibits carotid intimal thickening and ameliorates insulin resistance in balloon-injured diabetic ratsM Igarashi
Third Department of Internal Medicine, Yamagata University School of Medicine, Yamagata, Japan
Hypertension 38:1255-9. 2001..We conclude that candesartan could be effective for the suppression of vascular smooth muscle cell growth dose-dependently in Wistar fatty and lean rats. Furthermore, the agent could improve insulin resistance in Wistar fatty rats...
Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-adrenergic receptor is associated with type 2 diabetes and obesity in a large Japanese sampleT Oizumi
Third Department of Internal Medicine, Yamagata University School of Medicine, Yamagata, Japan
Diabetes Care 24:1579-83. 2001..We examined the associations in a large population-based sample...
Characterization of an inhibitory effect of pioglitazone on balloon-injured vascular smooth muscle cell growthM Igarashi
Third Department of Internal Medicine, Yamagata University School of Medicine, Yamagata, Japan
Metabolism 50:955-62. 2001..Pioglitazone also inhibited the phosphorylation of Pyk2. We conclude that pioglitazone itself could be effective for suppressing the growth of VSMC and consequent carotid intimal thickening...
Platelet-derived growth factor BB-induced p38 mitogen-activated protein kinase activation causes cell growth, but not apoptosis, in vascular smooth muscle cellsH Yamaguchi
Third Department of Internal Medicine, Yamagata University School of Medicine, Japan
Endocr J 48:433-42. 2001....
Prevalence of type 2 diabetes mellitus and impaired glucose tolerance in a rural area of Japan. The Funagata diabetes studyA Sekikawa
Third Department of Internal Medicine, Yamagata University School of Medicine, Japan
J Diabetes Complications 14:78-83. 2000....
Acute intermittent porphyria caused by a G to C mutation in exon 12 of the porphobilinogen deaminase gene that results in exon skippingM Daimon
Third Department of Internal Medicine, Yamagata University School of Medicine, Japan
Hum Genet 92:549-53. 1993..Analysis of the cDNA fragments amplified by PCR revealed that the patient has the abnormal PBG-D mRNA, which does not have exon 12 and exists in an approximately equal amount to the normal mRNA...
Pioglitazone reduces smooth muscle cell density of rat carotid arterial intima induced by balloon catheterizationM Igarashi
Department of Laboratory Medicine, Yamagata University School of Medicine, Japan
Horm Metab Res 29:444-9. 1997..Therefore, pioglitazone has an inhibitory effect on the growth of SMCs, and consequently suppressed carotid intimal thickening. Furthermore, this inhibitory effect was enhanced in diabetes...
Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes in balloon-injured diabetic ratsA Hirata
Department of Laboratory Medicine, Yamagata University School of Medicine, Yamagata, Japan
Horm Metab Res 41:213-20. 2009..These findings suggest that miglitol could be effective for the suppression of atherogenic outcomes in diabetic Wistar fatty rat, suggesting that the agent may have clinical benefits and contribute to prevent diabetic macroangiopathy...
A novel missense mutation in exon 4 of the human coproporphyrinogen oxidase gene in two patients with hereditary coproporphyriaM Daimon
Third Department of Internal Medicine, Yamagata University School of Medicine, Japan
Hum Genet 99:199-201. 1997..This mutation results in a glycine to arginine substitution at amino acid 180. Two carriers in the family were successfully diagnosed by detecting the mutation using restriction analysis of the PCR products...
[Standard material for measurement of hemoglobin A1c]M Tominaga
Department of Laboratory Medicine, Yamagata University School of Medicine, Yamagata 990-9585
Rinsho Byori 49:1199-204. 2001..3%. It is likely that the standardization of measurement of HbA1c in the future in Japan will be continued using with JDS Lot 2...
The metabolic syndrome and retinal microvascular signs in a Japanese population: the Funagata studyR Kawasaki
Department of Ophthalmology and Visual Science, Yamagata University Faculty of Medicine, Yamagata, Japan
Br J Ophthalmol 92:161-6. 2008..To determine the relationship of metabolic syndrome and its components with retinopathy and other retinal microvascular signs in a Japanese population...
Nifedipine suppresses neointimal thickening by its inhibitory effect on vascular smooth muscle cell growth via a MEK-ERK pathway coupling with Pyk2A Hirata
Department of Laboratory Medicine, Yamagata University School of Medicine, 2 2 2, Iida Nishi, Yamagata 990 9585, Japan
Br J Pharmacol 131:1521-30. 2000....
Two new polymorphisms in introns 2 and 3 of the human porphobilinogen deaminase geneM Daimon
Third Department of Internal Medicine, Yamagata University School of Medicine, Japan
Hum Genet 92:115-6. 1993..The frequencies of these alleles are presented...
BMI compared with central obesity indicators in relation to diabetes and hypertension in AsiansR Nyamdorj
Obesity (Silver Spring) 16:1622-35. 2008..760 (0.766) than WHR 0.748 (0.751), but their 95% CIs were all overlapped. DISCUSSION: WSR was stronger than BMI in association with diabetes, but these indicators were equally strongly associated with hypertension in Asians...
[Quality control (QC) of CT on rail system (FOCAL Unit) with a micro-multi leaf collimator (mMLC) using new GafChromic film for stereotactic radiotherapy]M Oita
School of Health Sciences, Faculty of Medicine, Tokushima University
Nippon Hoshasen Gijutsu Gakkai Zasshi 62:711-3. 2006..New type radiochromic film would be useful for a verification tool as alternative to conventional film...
Evaluation of the trifluoromethanosulfonic acid/trifluoroacetic acid/thioanisole cleavage procedure for application in solid-phase peptide synthesisG N Jubilut
Department of Biophysics, , SP, Brazil
Chem Pharm Bull (Tokyo) 49:1089-92. 2001..Care should be taken however, as the cleavage efficacy depends on multiple factors including the resin, peptide sequence, the time and temperature of reaction...
Temperament and job stress in Japanese company employeesY Sakai
Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
J Affect Disord 85:101-12. 2005..This study aims to demonstrate the relevance of temperament to job stress...
Legionnaires' disease associated with habitual drinking of hot spring waterM Tominaga
Department of Medicine, Saga Medical School
Intern Med 40:1064-7. 2001..The patient was successfully treated with erythromycin, fluoroquinolone, and rifampicin. This case raises an important issue on public health represented by legionellosis in Japan...
[Effect of caffeine on microcirculation of human ocular fundus]T Okuno
Department of Ophthalmology, Osaka Medical College, 2-7 Daigakucho, Takatsuki 569-8686, Japan
Nippon Ganka Gakkai Zasshi 105:308-13. 2001..IOP, mean BP, PR, OPP and central CFF did not change significantly. CONCLUSIONS: These results suggest that caffeine may increase blood vessel resistance and decrease blood flow in the ONH and choroid-retina in humans...
Urinary N-acetyl-beta-D-glucosaminidase in the patients with hyperthyroidismM Tominaga
First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan
Horm Metab Res 21:438-40. 1989....
