Akimitsu Takagi

Summary

Affiliation: Yakult Central Institute for Microbiological Research
Country: Japan

Publications

  1. doi request reprint Possibility of breast cancer prevention: use of soy isoflavones and fermented soy beverage produced using probiotics
    Akimitsu Takagi
    Pharmaceutical Research Laboratory, Yakult Central Institute, Tokyo 186 8650, Japan
    Int J Mol Sci 16:10907-20. 2015
  2. ncbi request reprint Three-dimensional cellular spheroid formation provides human prostate tumor cells with tissue-like features
    Akimitsu Takagi
    Department of Pathologic Oncology, Institute of Molecular and Experimental Medicine, Mie University Graduate School of Medicine, Tsu, Japan
    Anticancer Res 27:45-53. 2007
  3. pmc PEGylated liposome IHL-305 markedly improved the survival of ovarian cancer peritoneal metastasis in mouse
    Hiroaki Konishi
    Yakult Central Institute for Microbiological Research, 1790 Yaho, Kunitachi, Tokyo 1860 8650, Japan
    BMC Cancer 12:462. 2012
  4. doi request reprint Relationship between the in vitro response of dendritic cells to Lactobacillus and prevention of tumorigenesis in the mouse
    Akimitsu Takagi
    Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi, Tokyo 186 8650, Japan
    J Gastroenterol 43:661-9. 2008
  5. doi request reprint High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
    Yoshifumi S Hirokawa
    Department of Pathological Oncology, Institute of Molecular and Experimental Medicine, Faculty of Medicine, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie, 514 8507, Japan
    Cell Mol Biol Lett 12:370-7. 2007
  6. ncbi request reprint Identification of differentially methylated CpG islands in prostate cancer
    Yasushi Yamada
    Second Department of Pathology, Mie University School of Medicine, Tsu, Japan
    Int J Cancer 112:840-5. 2004
  7. ncbi request reprint Intestinal microflora: probiotics and autoimmunity
    Takeshi Matsuzaki
    Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi shi, Tokyo 186 8650, Japan
    J Nutr 137:798S-802S. 2007
  8. doi request reprint Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models
    Takeshi Matsuzaki
    Yakult Central Institute for Microbiological Research, Pharmaceutical Development Department, Yakult Honsha Co, Ltd, 1796 Yaho, Tokyo 186 8650, Japan
    Oncol Rep 27:189-97. 2012
  9. ncbi request reprint Antitumor activity and action mechanisms of Lactobacillus casei through the regulation of immune responses
    Takeshi Matsuzaki
    Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi shi, Tokyo 186 8650, Japan
    Biofactors 22:63-6. 2004

Collaborators

Detail Information

Publications9

  1. doi request reprint Possibility of breast cancer prevention: use of soy isoflavones and fermented soy beverage produced using probiotics
    Akimitsu Takagi
    Pharmaceutical Research Laboratory, Yakult Central Institute, Tokyo 186 8650, Japan
    Int J Mol Sci 16:10907-20. 2015
    ....
  2. ncbi request reprint Three-dimensional cellular spheroid formation provides human prostate tumor cells with tissue-like features
    Akimitsu Takagi
    Department of Pathologic Oncology, Institute of Molecular and Experimental Medicine, Mie University Graduate School of Medicine, Tsu, Japan
    Anticancer Res 27:45-53. 2007
    ..Alterations in the cellular biological responses were examined in a series of LNCaP human prostate tumor cells growing under different conditions...
  3. pmc PEGylated liposome IHL-305 markedly improved the survival of ovarian cancer peritoneal metastasis in mouse
    Hiroaki Konishi
    Yakult Central Institute for Microbiological Research, 1790 Yaho, Kunitachi, Tokyo 1860 8650, Japan
    BMC Cancer 12:462. 2012
    ..The aim of this study was to clarify aggressive pathology of peritoneal metastasis and examine the therapeutic efficacy of a liposomal agent in the model...
  4. doi request reprint Relationship between the in vitro response of dendritic cells to Lactobacillus and prevention of tumorigenesis in the mouse
    Akimitsu Takagi
    Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi, Tokyo 186 8650, Japan
    J Gastroenterol 43:661-9. 2008
    ..In this study, differences were compared among six representative strains of lactobacilli in regard to their ability to stimulate bone marrow cell-derived dendritic cells (BMDCs) in vitro and tumor suppression in vivo...
  5. doi request reprint High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone
    Yoshifumi S Hirokawa
    Department of Pathological Oncology, Institute of Molecular and Experimental Medicine, Faculty of Medicine, Mie University Graduate School of Medicine, 2 174 Edobashi, Tsu, Mie, 514 8507, Japan
    Cell Mol Biol Lett 12:370-7. 2007
    ..Comparing the two subclones, differentially expressed genes were identified, including E-cadherin, IL-8 and STAG1/PMEPA1. These genes were expressed at higher levels in mr than in M1...
  6. ncbi request reprint Identification of differentially methylated CpG islands in prostate cancer
    Yasushi Yamada
    Second Department of Pathology, Mie University School of Medicine, Tsu, Japan
    Int J Cancer 112:840-5. 2004
    ..The role of NTRK2 within NTRK remains unclear. Our results suggest that these 3 hypermethylated DNA fragments also may be markers of prostate cancer detection...
  7. ncbi request reprint Intestinal microflora: probiotics and autoimmunity
    Takeshi Matsuzaki
    Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi shi, Tokyo 186 8650, Japan
    J Nutr 137:798S-802S. 2007
    ..These results suggest that some probiotic bacteria have the potential to augment or modify the host immune function through the regulation of host immune cells...
  8. doi request reprint Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models
    Takeshi Matsuzaki
    Yakult Central Institute for Microbiological Research, Pharmaceutical Development Department, Yakult Honsha Co, Ltd, 1796 Yaho, Tokyo 186 8650, Japan
    Oncol Rep 27:189-97. 2012
    ..These results indicate that IHL-305 demonstrated superior antitumor activity against a wide range of tumors at lower doses than CPT-11...
  9. ncbi request reprint Antitumor activity and action mechanisms of Lactobacillus casei through the regulation of immune responses
    Takeshi Matsuzaki
    Yakult Central Institute for Microbiological Research, 1796 Yaho, Kunitachi shi, Tokyo 186 8650, Japan
    Biofactors 22:63-6. 2004
    ....