Research Topics
Genomes and GenesSpecies | Xiaojuan WangSummaryAffiliation: Wakayama Medical University Country: Japan Publications
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Detail Information
Publications
Gastrointestinal stromal tumors: clinicopathological study of Chinese casesX Wang
Department of Pathology, Wakayama Medical University, Wakayama, Japan
Pathol Int 51:701-6. 2001....
Metaplastic carcinoma of the breast: p53 analysis identified the same point mutation in the three histologic componentsX Wang
Department of Pathology, Wakayama Medical University, 811 1 Kimiidera, Wakayama City, Japan 641 0012
Mod Pathol 14:1183-6. 2001..Based on the morphologic findings, immunohistochemical findings and the p53 mutation analysis, we concluded that these three components in the tumor originated from the same duct progenitor cells...
Helpful parameter for malignant potential of gastrointestinal stromal tumors (GIST)Xiaojuan Wang
Department of Pathology, Wakayama Medical University, Wakayama City, Japan
Jpn J Clin Oncol 32:347-51. 2002..The older literature called all gastrointestinal stromal tumors smooth muscle tumors or mixed GIST with true smooth muscle tumors. Reports on GIST including homogeneous cases were rare...
Calcitonin receptor gene and breast cancer: quantitative analysis with laser capture microdissectionXiaojuan Wang
Department of Pathology, Wakayama Medical University, Wakayama City, Wakayama, Japan
Breast Cancer Res Treat 83:109-17. 2004..These results suggest that CTR might be of great potential significance in breast cancer progression...
Loss of cell cohesion in breast cytology as a characteristic of neuroendocrine carcinomaWeihua Tang
Department of Pathology, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, Wakayama, 641-8509 Japan
Acta Cytol 46:835-40. 2002..CONCLUSION: Loss of cell cohesion in breast cytology is a good morphologic marker for identifying neuroendocrine breast carcinoma...
Differentiation, proliferation and retinoid receptor status of papillary carcinoma of the thyroidWeihua Tang
Department of Pathology, Wakayama Medical University, Wakayama, Japan
Pathol Int 53:204-13. 2003..Loss of expression for one or more retinoid receptors frequently occurred in groups B and C. These results suggest that the loss of retinoid receptors might occur during the loss of differentiation and tumor progression of PTC...
p63 expression in normal, hyperplastic and malignant breast tissuesXiaojuan Wang
Department of Pathology, Wakayama Medical University, 811 1 Kimiidera, Wakayama City, Wakayama 641 0012, Japan
Breast Cancer 9:216-9. 2002..It has recently been confirmed that p63 is expressed in the basal cells of normal prostate glands but not in prostatic carcinomas. Whether expression of p63 in breast correlates with tumor progression is the focus of this study...
Gastrointestinal stromal tumors: are they of cajal cell origin?Xiaojuan Wang
Department of Pathology, Wakayama Medical University, 811 1 Kimiidera, Wakayama City, Japan 641 0012
Exp Mol Pathol 72:172-7. 2002..We suggest that the concept of GIST should not be used as an umbrella to cover all gastrointestinal mesenchymal tumors, but be defined in a narrow term as differing from true smooth muscle tumors...
Combined small-cell carcinoma of the stomach: p53 and K-ras gene mutational analysis supports a monoclonal origin of three histological componentsBo Han
Department of Pathology, Wakayama Medical University, Wakayama 641 8509, Japan
Int J Exp Pathol 86:213-8. 2005..Our results strongly support a hypothesis that the combined SmCC of stomach in this case was of monoclonal origin...
Myoepithelial carcinoma arising in an adenomyoepithelioma of the breast: case report with immunohistochemical and mutational analysisBo Han
Department of Pathology, Wakayama Medical University, Kimiidera, Wakayama, Japan
Pathol Int 56:211-6. 2006..No mutations in exons 1 and 2 of the K-, H-, and N-ras genes were identified in any of the neoplastic component. To the authors' knowledge this is the first report of a mutation in the p53 gene in a malignant AME of the breast...
Heparanase: a key enzyme in invasion and metastasis of gastric carcinomaWeihua Tang
Department of Pathology, Wakayama Medical University, Japan
Mod Pathol 15:593-8. 2002..It was indicated that patients with heparanase-positive gastric carcinoma would have a greater chance of metastasis with a poor prognosis...
A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosisVasan K Sambandamurthy
Howard Hughes Medical Institute and Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA
Nat Med 8:1171-4. 2002..Our findings highlight the importance of de novo pantothenate biosynthesis in limiting the intracellular survival and pathogenesis of M. tuberculosis without reducing its immunogenicity in vaccinated mice...
Effect of aging on neuroglobin expression in rodent brainYunjuan Sun
Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA
Neurobiol Aging 26:275-8. 2005..Loss of this neuroprotective protein may have a role in increasing susceptibility to age-related neurological disorders...
