Research Topics
Genomes and Genes | Nobuo KanazawaSummaryAffiliation: Wakayama Medical University Country: Japan Publications
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Detail Information
Publications
Cutaneous polyarteritis nodosa: revisiting its definition and diagnostic criteriaTomoyuki Nakamura
Department of Dermatology, School of Medicine, Wakayama Medical University, 811 1, Kimiidera, Wakayama 641 0012, Japan
Arch Dermatol Res 301:117-21. 2009..In conclusion, this study suggests that CPN does not progress to PN, and introduces new drafts for CPN and PN diagnostic criteria...- Effective treatment of intractable skin ulcers using allogeneic cultured dermal substitutes in patients with systemic lupus erythematosusSeiko Toyozawa
Department of Dermatology, School of Medicine, Wakayama Medical University, 811 1, Kimiidera, Wakayama, Japan
Eur J Dermatol 19:594-6. 2009..These results indicate that allogeneic CDSs provide new therapeutic alternatives as topical therapies for intractable skin ulcers in SLE... - Mast cells and histamine metabolism in skin lesions from MRL/MP-lpr/lpr miceFukumi Furukawa
Department of Dermatology, Wakayama Medical University, Wakayama City, Japan
Autoimmun Rev 8:495-9. 2009..The accumulation of mast cells expressing H2R and prolonged effects of histamine may occur to regulate the production of Th1 and Th2 cytokines in the skin lesions of MRL/l mice... - Influence of chemical peeling on the skin stress response systemAyako Kimura
Department of Dermatology, Naga Municipal Hospital, Wakayama, Japan
Exp Dermatol 21:8-10. 2012.... - Influence of trichloroacetic acid peeling on the skin stress response systemAyako Kimura
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
J Dermatol 38:740-7. 2011.... - Severe ulceration with impaired induction of growth factors and cytokines in keratinocytes after trichloroacetic acid application on TRPV1-deficient miceHong Jin Li
Department of Dermatology, Wakayama Medical University, 811 1 Kimiidera, Wakayama 641 0012, Japan
Eur J Dermatol 22:614-21. 2012.... - Nakajo-Nishimura syndrome: an autoinflammatory disorder showing pernio-like rashes and progressive partial lipodystrophyNobuo Kanazawa
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
Allergol Int 61:197-206. 2012.... - Effects of sarpogrelate hydrochloride on skin ulcers and quality of life in patients with systemic sclerosisTakashi Yoshimasu
Department of Dermatology, Arida Municipal Hospital, Arida, Japan
J Dermatol 39:536-40. 2012..The score was significantly improved after 6 months of sarpogrelate intake. There were no obvious side-effects during this study. Sarpogrelate was considered to be a useful drug to improve skin ulcers and QOL in patients with SSc... - Lupus erythematosus tumidus in Japan: a case report and a review of the literatureMizuho Nishiyama
Department of Dermatology, Wakayama Medical University, 811 1 Kimiidera, Wakayama, 641 0012, Japan
Mod Rheumatol 19:567-72. 2009..A review of ten LET cases previously reported in Japan revealed that all of these cases had clinicopathological features similar to those reported for European cases, although not all of the former fully satisfied the European criteria... 
[Genetic involvement of bacterial sensor molecules in Japanese leprosy]Nobuo Kanazawa
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
Nihon Hansenbyo Gakkai Zasshi 78:255-61. 2009..Especially, among those with a particular TLR2 -16934 genotype, frequency of the polymorphisms in DC-SIGN -336 showed significant difference between the patients and the controls, suggesting any cooperation of these SNPs...- Rare hereditary autoinflammatory disorders: towards an understanding of critical in vivo inflammatory pathwaysNobuo Kanazawa
Department of Dermatology, Wakayama Medical University, Wakayama 641 0012, Japan
J Dermatol Sci 66:183-9. 2012..Since there still remain a number of predicted but undefined hereditary autoinflammatory syndromes, further clinical and genetic approaches are required to discover novel in vivo critical inflammatory pathways... - Hydroxychloroquine administration for Japanese lupus erythematosus in Wakayama: a pilot studyTakaharu Ikeda
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
J Dermatol 39:531-5. 2012..An additional effect to improve lipid profiles was also observed in our Japanese cases. It is necessary to confirm that these effects are reproducible when Japanese lupus erythematosus cases are given HCQ... - Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hairTakashi Yoshimasu
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
J Dermatol 38:900-4. 2011..Collectively, it has been suggested that 736T>A transition is highly specific and common in ARWH/hypotrichosis of Japanese origin... 
The protective effects of ultraviolet A1 irradiation on spontaneous lupus erythematosus-like skin lesions in MRL/lpr miceNaoya Mikita
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
Clin Dev Immunol 2009:673952. 2009..Thus, UVA1 might exert its effects, at least in part, through the induction of the apoptosis of pathogenic mast cells. Our results supported the clinical efficacy of UVA1 irradiation for skin lesions of lupus patients...- Case report: a case of pyoderma gangrenosum with intractable leg ulcers treated by allogeneic cultured dermal substitutesSeiko Toyozawa
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
Dermatol Online J 14:17. 2008..Then the subsequent autologous skin graft was successfully performed. This indicates that CDS is one of the useful tools for the treatment of intractable ulcers in patients with PG... - Race differences in immunogenetic features and photosensitivity of cutaneous lupus erythematosus from the aspect of Japanese studiesFukumi Furukawa
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
Ann N Y Acad Sci 1173:552-6. 2009..The incidence and degree of photosensitivity of SCLE and LET are much lower in Japanese than in Caucasians. This discrepancy may lead to investigations of CLE pathogenesis through global collaborations... - [Pathogenesis of cutaneous lupus erythematosus from LE-prone mice]Fukumi Furukawa
Department of Dermatology, Wakayama Medical University
Nihon Rinsho Meneki Gakkai Kaishi 33:169-73. 2010..In this review, based on historical review, we focus on skin lesions from the well-studied MRL/lpr and B/W F1 mouse and discuss how SLE-prone mice can contribute to a better understanding of cutaneous LE pathogenesis... - [Nakajo-Nishimura syndrome]Nobuo Kanazawa
Department of Dermatology, Wakayama Medical University
Nihon Rinsho Meneki Gakkai Kaishi 34:388-400. 2011..S.A., and therefore, it is becoming clear that proteasome deficiency syndromes are globally distributed as a new category of the autoinflammatory diseases... - Autoinflammatory syndromes with a dermatological perspectiveNobuo Kanazawa
Department of Dermatology, Wakayama Medical University, Wakayama, Japan
J Dermatol 34:601-18. 2007..In this review, major autoinflammatory syndromes are summarized and the pathophysiology of related skin disorders is discussed in association with dysregulated innate immune signaling... - Induction of PDGF-B in TCA-treated epidermal keratinocytesNozomi Yonei
Department of Dermatology, School of Medicine, Wakayama Medical University, 811 1, Kimiidera, Wakayama 641 0012, Japan
Arch Dermatol Res 299:433-40. 2007..This effect might contribute to a promotion of re-epithelialization and dermal regeneration without wound contraction and scarring...