Research Topics
Genomes and GenesSpecies | Akihiko YoshidaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Detail Information
Publications
Soft-tissue hemangioblastoma of the retroperitoneum: a case study and review of the literatureAkihiko Yoshida
Clinical Laboratory Division, National Cancer Center Hospital, University of Tokyo, Tokyo, Japan
Appl Immunohistochem Mol Morphol 18:479-82. 2010..The patient is well 4 years after the surgery without any recurrence. A review of the literature revealed that soft-tissue hemangioblastoma is typically a solid tumor found in older females and often involves the retroperitoneum/pelvis...
Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimicsAkihiko Yoshida
Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
Mod Pathol 23:1279-88. 2010..MDM2 and CDK4 immunostains therefore reliably distinguish low-grade osteosarcoma from benign histological mimics, and their combination may serve as a useful adjunct in this difficult differential diagnosis...
Well-differentiated liposarcoma with low-grade osteosarcomatous component: an underrecognized variantAkihiko Yoshida
Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
Am J Surg Pathol 34:1361-6. 2010....
c-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomasKoji Tsuta
Division of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan
J Thorac Oncol 7:331-9. 2012..The aim of this study was to examine the correlations between c-MET/phospho-MET expression as well as MET gene copy number alterations and overall survival (OS) in non-small cell lung carcinomas (NSCLCs)...
Bright-field dual-color chromogenic in situ hybridization for diagnosing echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinomasAkihiko Yoshida
Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Japan
J Thorac Oncol 6:1677-86. 2011..In this study, we explored the potential of the ALK-break-apart chromogenic in situ hybridization (CISH) method to detect ALK-rearranged lung cancer...
Comprehensive histologic analysis of ALK-rearranged lung carcinomasAkihiko Yoshida
Pathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
Am J Surg Pathol 35:1226-34. 2011..ALK-positive cancers commonly showed coexpression of thyroid transcription factor-1 and p63, and its significance is currently unclear...
MDM2 and CDK4 immunohistochemical coexpression in high-grade osteosarcoma: correlation with a dedifferentiated subtypeAkihiko Yoshida
Departments of Pathology and Clinical Laboratories, National Cancer Center Research Institute, Tokyo, Japan
Am J Surg Pathol 36:423-31. 2012....
Utility of 10 immunohistochemical markers including novel markers (desmocollin-3, glypican 3, S100A2, S100A7, and Sox-2) for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the LungKoji Tsuta
Division of Pathology and Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
J Thorac Oncol 6:1190-9. 2011..Recent clinical trials revealed that accurate histologic typing of non-small cell lung cancer, especially squamous cell carcinoma (SCC), is essential...
NKX2.2 is a useful immunohistochemical marker for Ewing sarcomaAkihiko Yoshida
Pathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
Am J Surg Pathol 36:993-9. 2012..All the other non-Ewing tumors tested were negative for this marker. NKX2.2 is a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors...
Steroid receptor expression in thymomas and thymic carcinomasTakahiro Mimae
Pathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan
Cancer 117:4396-405. 2011....
Extraskeletal myxoid chondrosarcoma: a review of 23 patients treated at a single referral center with long-term follow-upKoichi Ogura
Division of Musculoskeletal Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Arch Orthop Trauma Surg 132:1379-86. 2012..The aim of this study was to clarify the long-term clinical features of EMC treated at a single referral center using state-of-the-art techniques...
The usefulness of mutation-specific antibodies in detecting epidermal growth factor receptor mutations and in predicting response to tyrosine kinase inhibitor therapy in lung adenocarcinomaYoshiki Kozu
Division of Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan
Lung Cancer 73:45-50. 2011..The ability to detecting such mutations using immunohistochemistry (IHC) would be advantageous...
Frequent ALK rearrangement and TTF-1/p63 co-expression in lung adenocarcinoma with signet-ring cell componentAkihiko Yoshida
Clinical Laboratory Division, National Cancer Center Hospital, Japan
Lung Cancer 72:309-15. 2011..The characteristic histology, immunoprofile, frequent ALK translocation, and total lack of EGFR or KRAS mutations, may suggest that Ad-SRCC forms a histologically/molecularly coherent subgroup of adenocarcinoma...
Validation study on pfetin and ATP-dependent RNA helicase DDX39 as prognostic biomarkers in gastrointestinal stromal tumourDaisuke Kubota
Division of Pharmacoproteomics, National Cancer Center Research Institute, Tokyo, Japan
Jpn J Clin Oncol 42:730-41. 2012..Prognostic biomarkers have long been required for the optimal use of kinase inhibitors in gastrointestinal stromal tumour...
Alveolar soft part sarcoma: a single-center 26-patient case series and review of the literatureKoichi Ogura
Division of Musculoskeletal Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
Sarcoma 2012:907179. 2012..Conclusions. ASPS is indolent but has a high propensity for metastasis. Early diagnosis and complete excision of the small primary tumor are essential in the treatment of ASPS...
