Kazuya Yamada


Affiliation: University of Fukui
Country: Japan


  1. request reprint
    Yamada K, Osawa H, Granner D. Identification of proteins that interact with NF-YA. FEBS Lett. 1999;460:41-5 pubmed
    ..Two different domains of NF-YA, a glutamine-rich region and a serine/threonine-rich region, are necessary for the interactions with ZHX1 and SRF, respectively. ..
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    Yamada K, Mizutani T, Shou Z, Yazawa T, Sekiguchi T, Yoshino M, et al. Cloning and functional expression of an E box-binding protein from rat granulosa cells. Biol Reprod. 2001;64:1315-9 pubmed
    ..Thus, we report molecular cloning, expression, and functional characterization of full-length rat USF2 cDNA. ..
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    Yamada K, Kawata H, Matsuura K, Shou Z, Hirano S, Mizutani T, et al. Functional analysis and the molecular dissection of zinc-fingers and homeoboxes 1 (ZHX1). Biochem Biophys Res Commun. 2002;297:368-74 pubmed
    ..The acidic region corresponding to the amino acid sequence between 831 and 873 was a repressor domain and dimerization was prerequisited for full repressor activity. ..
  4. Yamada K, Kawata H, Shou Z, Hirano S, Mizutani T, Yazawa T, et al. Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3. Biochem J. 2003;373:167-78 pubmed
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    Yamada K, Kawata H, Shou Z, Mizutani T, Noguchi T, Miyamoto K. Insulin induces the expression of the SHARP-2/Stra13/DEC1 gene via a phosphoinositide 3-kinase pathway. J Biol Chem. 2003;278:30719-24 pubmed
    ..In addition, nuclear run-on assay revealed that transcription of the rat SHARP-2 gene was induced by insulin. Thus, we conclude that insulin induces the transcription of the rat SHARP-2 gene via a phosphoinositide 3-kinase pathway. ..
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    Yamada K, Kawata H, Mizutani T, Arima T, Yazawa T, Matsuura K, et al. Gene expression of basic helix-loop-helix transcription factor, SHARP-2, is regulated by gonadotropins in the rat ovary and MA-10 cells. Biol Reprod. 2004;70:76-82 pubmed
    ..We conclude that the level of SHARP-2 mRNA is regulated by gonadotropins and that SHARP-2 functions as a transcriptional repressor localized in the nucleus. ..
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    Yamada K, Ogata Kawata H, Matsuura K, Miyamoto K. SHARP-2/Stra13/DEC1 as a potential repressor of phosphoenolpyruvate carboxykinase gene expression. FEBS Lett. 2005;579:1509-14 pubmed
    ..Based on these findings, we conclude that SHARP-2 is a potential repressor of PEPCK gene expression. ..
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    Yamada K, Miyamoto K. Basic helix-loop-helix transcription factors, BHLHB2 and BHLHB3; their gene expressions are regulated by multiple extracellular stimuli. Front Biosci. 2005;10:3151-71 pubmed
    ..The structural features, functions, and biological roles of the novel bHLH transcription factors, BHLHB2 and BHLHB3, are discussed along with the mechanisms in which the genes encoding these factors are regulated. ..