Hiroshi Yamada

Summary

Affiliation: University of Shizuoka
Country: Japan

Publications

  1. ncbi request reprint Gargling with tea catechin extracts for the prevention of influenza infection in elderly nursing home residents: a prospective clinical study
    Hiroshi Yamada
    Division of Drug Evaluation and Informatics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
    J Altern Complement Med 12:669-72. 2006
  2. ncbi request reprint A randomized clinical study of tea catechin inhalation effects on methicillin-resistant Staphylococcus aureus in disabled elderly patients
    Hiroshi Yamada
    Division of Drug Evaluation and Informatics, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
    J Am Med Dir Assoc 7:79-83. 2006
  3. ncbi request reprint An artifact derived from a pseudogene led to the discovery of microRNA binding site polymorphism in the 3'-untranslated region of the human dihydrofolate reductase gene
    Hideki Hayashi
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka
    Drug Metab Pharmacokinet 27:263-7. 2012
  4. ncbi request reprint A single nucleotide polymorphism of reduced folate carrier 1 predicts methotrexate efficacy in Japanese patients with rheumatoid arthritis
    Hideki Hayashi
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, and Department of Rheumatology, Shizuoka Kousei Hospital, Shizuoka, Japan
    Drug Metab Pharmacokinet 28:164-8. 2013
  5. ncbi request reprint Dihydrofolate reductase gene intronic 19-bp deletion polymorphisms in a Japanese population
    Hideki Hayashi
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
    Drug Metab Pharmacokinet 25:516-8. 2010
  6. pmc Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: a randomized controlled trial
    Keiji Matsumoto
    Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Yada, Suruga ku, Shizuoka, Japan
    BMC Complement Altern Med 11:15. 2011
  7. doi request reprint Green tea consumption is inversely associated with the incidence of influenza infection among schoolchildren in a tea plantation area of Japan
    Mijong Park
    Department of Drug Evaluation and Informatics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
    J Nutr 141:1862-70. 2011
  8. ncbi request reprint Assessing nonlinearity in compartment models via the relative curvature measure
    Takashi Daimon
    Division of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52 1, Yada, Suruga ku, Shizuoka, 422 8526, Japan
    J Pharmacokinet Pharmacodyn 34:207-27. 2007
  9. doi request reprint Reactive oxygen species assay-based risk assessment of drug-induced phototoxicity: classification criteria and application to drug candidates
    Satomi Onoue
    Department of Pharmacokinetics and Pharmacodynamics and Global Center of Excellence COE Program, School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan
    J Pharm Biomed Anal 47:967-72. 2008
  10. doi request reprint Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis
    Chihiro Fujimaki
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Suruga ku, Shizuoka, Japan
    Biomarkers 14:49-54. 2009

Collaborators

  • Hiroshi Watanabe
  • Yukihiko Hara
  • Shizuo Yamada
  • Takashi Daimon
  • Satomi Onoue
  • Naoko Igarashi
  • Masashi Goto
  • K Umegaki
  • M Takahata
  • Naoyuki Kurokawa
  • Hideki Hayashi
  • Kazuhiro Kosuge
  • Kazuyuki Inoue
  • Taiji Matsuyama
  • Seiji Tsuboi
  • Kunihiko Itoh
  • Yui Tazoe
  • Masato Horino
  • Daiki Tsuji
  • Mariko Morishita
  • Keiji Matsumoto
  • Mijong Park
  • Chihiro Fujimaki
  • Masafumi Motohashi
  • Shinya Uchida
  • Teppei Akiyama
  • Toshinori Nishikimi
  • Kotaro Yamakado
  • Hiroshi Miyazaki
  • Nobuhiko Nomura
  • Teruhisa Arai
  • Motohiro Ohshima
  • Chihiro Fujimaki-Katoh
  • Takahiro Goto
  • Toshiro Kitagawa
  • Shinya Kaji
  • Yuko M Sagesaka
  • Yuko Okada
  • Kumi Matsushita
  • Hitoshi Niino
  • Norikata Takuma
  • Xiao Dong Li
  • Atsuto Sugaya
  • Hideyuki Kato
  • Shuji Maruyama
  • Kyoichi Ohashi
  • Yuki Ohmori
  • Mitsuko Furuta
  • Tomomi Oki
  • Setsuko Sato
  • Toshiko Imai
  • Fujio Genkai
  • Masao Maeno
  • Hiroaki Kobayashi
  • Ryo Ishida
  • Kouji Obata
  • Keisuke Yokoi
  • Katsuro Tomita
  • Katsuhiko Kitaoka
  • Toshiharu Tazawa
  • Ichidai Kudoh
  • Ryuichi Nakamura
  • Maria Ohta
  • Kensaku Hashiba
  • Junichi Fujimoto
  • Junichi Mitsuyama
  • Yousuke Furuta
  • Mitsunori Nakata
  • Shinzaburo Minami
  • Toshiko Fukuda

Detail Information

Publications23

  1. ncbi request reprint Gargling with tea catechin extracts for the prevention of influenza infection in elderly nursing home residents: a prospective clinical study
    Hiroshi Yamada
    Division of Drug Evaluation and Informatics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
    J Altern Complement Med 12:669-72. 2006
    ..To evaluate the effects of gargling tea catechin extracts on the prevention of influenza infection in elderly nursing home residents...
  2. ncbi request reprint A randomized clinical study of tea catechin inhalation effects on methicillin-resistant Staphylococcus aureus in disabled elderly patients
    Hiroshi Yamada
    Division of Drug Evaluation and Informatics, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
    J Am Med Dir Assoc 7:79-83. 2006
    ..To evaluate the effects of tea catechin inhalation on methicillin-resistant Staphylococcus aureus (MRSA) in disabled elderly patients...
  3. ncbi request reprint An artifact derived from a pseudogene led to the discovery of microRNA binding site polymorphism in the 3'-untranslated region of the human dihydrofolate reductase gene
    Hideki Hayashi
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka
    Drug Metab Pharmacokinet 27:263-7. 2012
    ..This study is a reinvestigation of a newly discovered genetic polymorphism...
  4. ncbi request reprint A single nucleotide polymorphism of reduced folate carrier 1 predicts methotrexate efficacy in Japanese patients with rheumatoid arthritis
    Hideki Hayashi
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, and Department of Rheumatology, Shizuoka Kousei Hospital, Shizuoka, Japan
    Drug Metab Pharmacokinet 28:164-8. 2013
    ..The results of this study suggest that the RFC1 G80A polymorphism may be a useful marker for predicting MTX efficacy in Japanese patients with RA...
  5. ncbi request reprint Dihydrofolate reductase gene intronic 19-bp deletion polymorphisms in a Japanese population
    Hideki Hayashi
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
    Drug Metab Pharmacokinet 25:516-8. 2010
    ....
  6. pmc Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: a randomized controlled trial
    Keiji Matsumoto
    Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, Yada, Suruga ku, Shizuoka, Japan
    BMC Complement Altern Med 11:15. 2011
    ..This study was conducted to determine whether taking green tea catechins and theanine can clinically prevent influenza infection...
  7. doi request reprint Green tea consumption is inversely associated with the incidence of influenza infection among schoolchildren in a tea plantation area of Japan
    Mijong Park
    Department of Drug Evaluation and Informatics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
    J Nutr 141:1862-70. 2011
    ..30-0.94); P = 0.03], respectively. However, there was no significant association with the consumption of >5 cups/d. Our findings thus suggest that the consumption of 1-5 cups/d of green tea may prevent influenza infection in children...
  8. ncbi request reprint Assessing nonlinearity in compartment models via the relative curvature measure
    Takashi Daimon
    Division of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52 1, Yada, Suruga ku, Shizuoka, 422 8526, Japan
    J Pharmacokinet Pharmacodyn 34:207-27. 2007
    ..The results showed that the relative curvature measure with the variance function was not affected by heteroscedastic blood drug concentration data and could be utilized for the assessment of the nonlinearity in compartment models...
  9. doi request reprint Reactive oxygen species assay-based risk assessment of drug-induced phototoxicity: classification criteria and application to drug candidates
    Satomi Onoue
    Department of Pharmacokinetics and Pharmacodynamics and Global Center of Excellence COE Program, School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan
    J Pharm Biomed Anal 47:967-72. 2008
    ..These results verify the usefulness of the ROS assay for understanding the phototoxicity risk of pharmaceutical substances, and the ROS assay can be used for screening purposes in the drug discovery stage...
  10. doi request reprint Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis
    Chihiro Fujimaki
    Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Suruga ku, Shizuoka, Japan
    Biomarkers 14:49-54. 2009
    ..Therefore, we conclude that homocysteine might affect the inflammatory status of patients, and the MTHFR 677C>T SNP could be a predictive factor of hyperhomocysteinemia in patients with RA...
  11. ncbi request reprint Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers
    Shinya Uchida
    Department of Pharmacokinetics, Center of Excellence Program in the 21st Century, School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka, 422 8526, Japan
    J Clin Pharmacol 46:1290-8. 2006
    ..Thus, it is suggested that the combination of GBE and drugs should be cautious in terms of the potential interactions, especially in elderly patients or patients treated with drugs exerting relatively narrow therapeutic windows...
  12. ncbi request reprint Employing dmft score as a risk predictor for caries development in the permanent teeth in Japanese primary school girls
    Masafumi Motohashi
    Department of Oral Health Sciences, Nihon University School of Dentistry, Tokyo, Japan
    J Oral Sci 48:233-7. 2006
    ..In both cohorts, the risk ratio for permanent teeth caries was significant for many cut-off levels of dmft. The results indicated that the dmft score is a useful predictor of the permanent teeth caries in Japanese primary school girls...
  13. ncbi request reprint Tea polyphenols in preventing cardiovascular diseases
    Hiroshi Yamada
    Cardiovasc Res 73:439-40. 2007
  14. ncbi request reprint [In order to perform clinical trials efficiently in Japan--important issues in medical institutions raised by the GCP on-site review]
    Teppei Akiyama
    The Office of Conformity Audit, Pharmaceuticals and Medical Devices Agency
    Nihon Kokyuki Gakkai Zasshi 44:541-9. 2006
    ..We hope that our findings at investigational sites will promote the protection of human rights and improve the quality of clinical trials in Japan...
  15. pmc Evaluation of T-3811ME (BMS-284756), a new des-F(6)-quinolone, for treatment of meningitis caused by penicillin-resistant Streptococcus pneumoniae in rabbits
    Masahiro Takahata
    Research Laboratories, Toyama Chemical Co, Ltd, Toyama, Japan
    Antimicrob Agents Chemother 46:1760-5. 2002
    ..T-3811ME (BMS-284756) may be expected to be evaluated for the management of meningitis caused by highly penicillin-resistant pneumococci...
  16. ncbi request reprint [In vitro and in vivo antibacterial activities of pazufloxacin mesilate, a new injectable quinolone]
    Nobuhiko Nomura
    Jpn J Antibiot 55:412-39. 2002
    ..6) Intravenous administration of PZFX with high plasma concentration just after administration, showed more excellent therapeutic effect against the rat intraperitoneal infection, than p.o. and s.c. administration...
  17. ncbi request reprint Influence of stability on range of motion after cruciate-retaining TKA
    Kotaro Yamakado
    Department of Orthopaedic Surgery, School of Medicine, Kanazawa University, 13 1, Takara machi, Kanazawa, 920 8641, Japan
    Arch Orthop Trauma Surg 123:1-4. 2003
    ..A loosely balanced total knee arthroplasty (TKA) is reported to produce a good postoperative range of motion (ROM), but too much laxity is thought to be the cause of persistent pain and worsened functionality...
  18. ncbi request reprint [The effects of inhaled carbon monoxide on lung injury in rats caused by lipopolysaccharide]
    Hiroshi Miyazaki
    Department of Anesthesia, Chigasaki Municipal Hospital, Chigasaki 253 0042
    Masui 52:363-9. 2003
    ..Carbon monoxide (CO) has long been considered a toxic substance. Recent studies have revealed that CO may play an important role in intercellular signaling. We hypothesized that CO modulates the inflammatory mechanisms...
  19. ncbi request reprint New electronic device for monitoring medication compliance
    Hiroshi Yamada
    Am J Health Syst Pharm 60:1910-1. 2003
  20. ncbi request reprint [A case of multiple lung metastases and cervical lymph node metastasis of renal cell carcinoma failing to respond to interferon-alpha (IFN-alpha) but markedly responding to interleukin-2 (IL-2)]
    Toshinori Nishikimi
    Department of Urology, Nagoya Daini Red Cross Hospital
    Nihon Hinyokika Gakkai Zasshi 95:54-8. 2004
    ..Therefore, the tumor response to IL-2 was suggested to depend on NK activity and LAK activity...
  21. ncbi request reprint Lymphocyte and plasma vitamin C levels in type 2 diabetic patients with and without diabetes complications
    Hiroshi Yamada
    General Clinical Research Center, Hamamatsu University School of Medicine, Japan
    Diabetes Care 27:2491-2. 2004
  22. ncbi request reprint Pharmacokinetic and pharmacodynamic interactions between simvastatin and diltiazem in patients with hypercholesterolemia and hypertension
    Hiroshi Watanabe
    Department of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu 431 3192, Japan
    Life Sci 76:281-92. 2004
    ....
  23. ncbi request reprint [In vitro interaction of tazobactam/piperacillin combined with aminoglycosides against Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli AND Staphylococcus aureus]
    Hiroshi Yamada
    Research Laboratories, Toyama Chemical Co, Ltd, 4 1, Shimookui 2 chome, Toyama 930 8508, Japan
    Jpn J Antibiot 55:61-6. 2002
    ..In conclusion, these results suggest that the combination therapies of TAZ/PIPC with aminoglycosides are useful for the clinical treatment of sepsis caused by above four species...