Chiho Watanabe

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint Modification of mercury toxicity by selenium: practical importance?
    Chiho Watanabe
    Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
    Tohoku J Exp Med 196:71-7. 2002
  2. pmc Mutual interaction between nutritional status and chronic arsenic toxicity due to groundwater contamination in an area of Terai, lowland Nepal
    Makhan Maharjan
    Department of Human Ecology, School of International Health, Graduate School of Medicine, Universit of Tokyo, Tokyo, Japan
    J Epidemiol Community Health 61:389-94. 2007
  3. ncbi request reprint Effects of perinatal exposure to low-dose cadmium on thyroid hormone-related and sex hormone receptor gene expressions in brain of offspring
    Hiromi Ishitobi
    Department of Human Ecology, School of International Health, Graduate School of Medicine, The University of Tokyo, Japan
    Neurotoxicology 28:790-7. 2007
  4. ncbi request reprint Gender difference in daily time and space use among Bangladeshi villagers under arsenic hazard: application of the compact spot-check method
    Ryutaro Ohtsuka
    Department of Human Ecology, School of International Health, University of Tokyo, Hongo, Tokyo 113 0033, Japan
    J Biosoc Sci 36:317-32. 2004
  5. ncbi request reprint Arsenic contamination in drinking water and skin manifestations in lowland Nepal: the first community-based survey
    Makhan Maharjan
    Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Am J Trop Med Hyg 73:477-9. 2005
  6. ncbi request reprint Effects of low-dose perinatal cadmium exposure on tissue zinc and copper concentrations in neonatal mice and on the reproductive development of female offspring
    Hiromi Ishitobi
    Department of Human Ecology, School of International Health, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Toxicol Lett 159:38-46. 2005
  7. ncbi request reprint Dermatological and nutritional/growth effects among children living in arsenic-contaminated communities in rural Bangladesh
    Chiho Watanabe
    Department of Human Ecology, Graduate School of Medicine, University of Tokyo
    J Environ Sci Health A Tox Hazard Subst Environ Eng 42:1835-41. 2007
  8. ncbi request reprint Pesticide usage and its association with health symptoms among farmers in rural villages in West Java, Indonesia
    Makiko Sekiyama
    Transdisciplinary Initiative for Global Sustainability, Integrated Research System for Sustainability Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Environ Sci 14:23-33. 2007
  9. ncbi request reprint Water intake in an Asian population living in arsenic-contaminated area
    Chiho Watanabe
    Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Toxicol Appl Pharmacol 198:272-82. 2004
  10. pmc Exposure assessment of phthalate esters in Japanese pregnant women by using urinary metabolite analysis
    Yayoi Suzuki
    Department of Environmental Studies, The University of Tokyo, Kashiwanoha 5 1 5, Kashiwa, Chiba, 270 8563, Japan
    Environ Health Prev Med 14:180-7. 2009

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Modification of mercury toxicity by selenium: practical importance?
    Chiho Watanabe
    Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
    Tohoku J Exp Med 196:71-7. 2002
    ..Compared to the experimental findings, little evidence of the toxicological modification of MeHg by selenium was obtained in epidemiological studies...
  2. pmc Mutual interaction between nutritional status and chronic arsenic toxicity due to groundwater contamination in an area of Terai, lowland Nepal
    Makhan Maharjan
    Department of Human Ecology, School of International Health, Graduate School of Medicine, Universit of Tokyo, Tokyo, Japan
    J Epidemiol Community Health 61:389-94. 2007
    ..To reveal the inter-relationship between nutritional status and arsenic toxicity...
  3. ncbi request reprint Effects of perinatal exposure to low-dose cadmium on thyroid hormone-related and sex hormone receptor gene expressions in brain of offspring
    Hiromi Ishitobi
    Department of Human Ecology, School of International Health, Graduate School of Medicine, The University of Tokyo, Japan
    Neurotoxicology 28:790-7. 2007
    ..Our study indicates that alteration in the gene expressions of RC3 and sex hormone receptors in the brain induced by perinatal Cd and MMI exposure might be one mechanism of developmental toxicity of Cd...
  4. ncbi request reprint Gender difference in daily time and space use among Bangladeshi villagers under arsenic hazard: application of the compact spot-check method
    Ryutaro Ohtsuka
    Department of Human Ecology, School of International Health, University of Tokyo, Hongo, Tokyo 113 0033, Japan
    J Biosoc Sci 36:317-32. 2004
    ..Discussion focuses on the advantages of the compact spot-check method and the possibility that males' larger energy expenditure and longer exposure to sunlight are responsible for their severer skin manifestations...
  5. ncbi request reprint Arsenic contamination in drinking water and skin manifestations in lowland Nepal: the first community-based survey
    Makhan Maharjan
    Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Am J Trop Med Hyg 73:477-9. 2005
    ..9%, which was comparable to those found by the same examiner in arsenic-contaminated areas in Bangladesh, and that males had prevalence a twice as high as females, which could not be explained by the difference in the exposure level...
  6. ncbi request reprint Effects of low-dose perinatal cadmium exposure on tissue zinc and copper concentrations in neonatal mice and on the reproductive development of female offspring
    Hiromi Ishitobi
    Department of Human Ecology, School of International Health, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Toxicol Lett 159:38-46. 2005
    ..These findings suggest that perinatal Cd exposure, even at low levels, affects the Zn and Cu concentrations of neonates and the reproductive functions of female offspring...
  7. ncbi request reprint Dermatological and nutritional/growth effects among children living in arsenic-contaminated communities in rural Bangladesh
    Chiho Watanabe
    Department of Human Ecology, Graduate School of Medicine, University of Tokyo
    J Environ Sci Health A Tox Hazard Subst Environ Eng 42:1835-41. 2007
    ....
  8. ncbi request reprint Pesticide usage and its association with health symptoms among farmers in rural villages in West Java, Indonesia
    Makiko Sekiyama
    Transdisciplinary Initiative for Global Sustainability, Integrated Research System for Sustainability Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Environ Sci 14:23-33. 2007
    ..Preventing such behaviors will be an effective method of reducing health problems among the subject farmers...
  9. ncbi request reprint Water intake in an Asian population living in arsenic-contaminated area
    Chiho Watanabe
    Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Toxicol Appl Pharmacol 198:272-82. 2004
    ....
  10. pmc Exposure assessment of phthalate esters in Japanese pregnant women by using urinary metabolite analysis
    Yayoi Suzuki
    Department of Environmental Studies, The University of Tokyo, Kashiwanoha 5 1 5, Kashiwa, Chiba, 270 8563, Japan
    Environ Health Prev Med 14:180-7. 2009
    ....
  11. ncbi request reprint Low-dose perinatal diethylstilbestrol exposure affected behaviors and hypothalamic estrogen receptor-alpha-positive cells in the mouse
    Mika Tanaka
    Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo, Tokyo, 113 0033, Japan
    Neurotoxicol Teratol 26:261-9. 2004
    ..The relationship between the increase in ER-IR cells and behavioral changes should be further examined...
  12. ncbi request reprint Effects of arsenic on younger generations
    Chiho Watanabe
    Department of Human Ecology, School of International Health, Graduate School of Medical Sciences, University of Tokyo, Japan
    J Environ Sci Health A Tox Hazard Subst Environ Eng 38:129-39. 2003
    ..Considering the public health importance of toxic effects imposed during the early life stages, it is clear that much more scientific efforts should be made to elucidate the possible effects of arsenic on the younger generations...
  13. ncbi request reprint Skin manifestations of arsenicosis in two villages in Bangladesh
    Takafumi Kadono
    Department of Dermatology, Faculty of Medicine, School of International Health, University of Tokyo, Tokyo, Japan
    Int J Dermatol 41:841-6. 2002
    ..As skin manifestations are sensitive markers of arsenicosis, we examined the skin of adults and adolescents in two villages to elucidate the severity of arsenicosis...
  14. doi request reprint Behavioral and nutritional factors and geohelminth infection among two ethnic groups in the Terai region, Nepal
    Rajendra Prasad Parajuli
    Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, 113 0033 Japan
    Am J Hum Biol 21:98-104. 2009
    ....
  15. ncbi request reprint Arsenic in cooked rice in Bangladesh
    Munjoo Bae
    Department of Human Ecology, School of International Health, Graduate School of Medical Sciences, University of Tokyo, Hongo 7 3 1, Bunkyo ku, 113 0033, Tokyo, Japan
    Lancet 360:1839-40. 2002
    ..The method of cooking and water used can affect the amount of arsenic in cooked rice, which will have implications for the assessment of the health risks of arsenic...
  16. ncbi request reprint No difference in serum leptin concentrations between urban-dwelling Austronesians and Non-Austronesians in Papua New Guinea
    Mika Tanaka
    Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Am J Hum Biol 17:696-703. 2005
    ..In conclusion, the NAN populations do not endogenously differ in leptin status from the AN populations, who have been recognized as a typical group with a "thrifty" genotype...
  17. ncbi request reprint Severe toxicity and cyclooxygenase (COX)-2 mRNA increase by lithium in the neonatal mouse kidney
    Wataru Yoshioka
    Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    J Toxicol Sci 34:519-25. 2009
    ..The present results showed that the kidney of mouse neonates is vulnerable to lithium, and suggested the possibility that COX-2 upregulation is responsible for the severe renal toxicity including hydronephrosis...
  18. ncbi request reprint [Estimation of intake level of di (2-ethyhexyl) phthalate (DEHP) in Japanese pregnant women based on measurement of concentrations of three urinary metabolites]
    Kayumi Fujimaki
    Institute of Environmental Studies, University of Tokyo, Tokyo, Japan
    Nihon Eiseigaku Zasshi 61:340-7. 2006
    ..corrected] The daily intake level of di (2-ethyhexyl) phthalate (DEHP) of Japanese pregnant women was estimated on the basis of the measurement of the urinary concentrations of three DEHP metabolites...
  19. ncbi request reprint Impacts of dietary intake and helminth infection on diversity in growth among schoolchildren in rural south China: a four-year longitudinal study
    Huan Zhou
    Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
    Am J Hum Biol 19:96-106. 2007
    ..japonicum...
  20. doi request reprint Twenty years' demographic change in sedentes and migrants of an international migrant-sending community in Tonga
    Shoko Fukuyama
    Department of Human Ecology, School of International Health, University of Tokyo, Japan
    J Biosoc Sci 41:77-87. 2009
    ..If the current trends of international migration and fertility continue, the population of Kolovai will be reduced and its age composition will become cylinder-shaped in the near future...
  21. ncbi request reprint Neurobehavioral changes in metallothionein-null mice prenatally exposed to mercury vapor
    Minoru Yoshida
    Department of Biochemistry, Division of Chemistry, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, Kawasaki 261 8511, Japan
    Toxicol Lett 155:361-8. 2005
    ..From these results, we suggest that the increased susceptibility of MT-null females to behavioral changes caused by prenatal Hg0 exposure is due to a greater retention of mercury and lack of MT-I,-II in the brain...
  22. ncbi request reprint The effects of gestational arsenic exposure and dietary selenium deficiency on selenium and selenoenzymes in maternal and fetal tissues in mice
    Kaori Miyazaki
    Department of Public Health, Division of Environmental Medicine, Gunma University Graduate School of Medicine, 3 39 22, Maebashi City, Gunma 371 8510, Japan
    Toxicology 208:357-65. 2005
    ....
  23. ncbi request reprint Arsenicosis in two villages in Terai, lowland Nepal
    Sk Akhtar Ahmad
    Department of Occupational and Environmental Health, National Institute of Preventive and Social Medicine NIPSOM, Mohakhali, Dhaka 1212, Bangladesh
    Environ Sci 11:179-88. 2004
    ..3% of the identified patients. Only one patient had Bowen's disease. To our knowledge, the current study provides for the first time quantitative information regarding the arsenicosis patients in Nepal...
  24. ncbi request reprint Behavioral changes in metallothionein-null mice after the cessation of long-term, low-level exposure to mercury vapor
    Minoru Yoshida
    Department of Biochemistry, Division of Chemistry, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, Kawasaki 261 8511, Japan
    Toxicol Lett 161:210-8. 2006
    ..Finally, the MT-null mice seemed more susceptible to Hg0-induced neurotoxicity than the wild-type mice, confirming our previous results...
  25. ncbi request reprint Gender differences in food and energy intake among adult villagers in northwestern Bangladesh: a food frequency questionnaire survey
    Noriko Sudo
    Department of Health Promotion and Research, National Institute of Public Health, 2 3 6 minami, Wako Shi, Saitama Prefecture, 351 0197, Japan
    Int J Food Sci Nutr 55:499-509. 2004
    ..8%) and females (37.8%), attributing to males' larger energy expenditure. Females' less-frequent consumption of nutritious foods and smaller energy intake were considered vulnerable to micronutrient deficiency...
  26. ncbi request reprint Prevalence of arsenicosis in terai, Nepal
    Makhan Maharjan
    Environment and Public Health Organization, New Baneshwor, PO Box 4102, Kathmandu, Nepal
    J Health Popul Nutr 24:246-52. 2006
    ..Most patients were identified in the early or mild stage of the disease. They are expected to recover if further exposure to arsenic could be avoided by providing arsenic-safe drinking-water through intervention measures...
  27. ncbi request reprint Effects of perinatal exposure to low doses of cadmium or methylmercury on thyroid hormone metabolism in metallothionein-deficient mouse neonates
    Kouki Mori
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Sendai, Japan
    Toxicology 228:77-84. 2006
    ....
  28. ncbi request reprint Methylmercury inhibition of type II 5'-deiodinase activity resulting in a decrease in growth hormone production in GH3 cells
    Kouki Mori
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Toxicology 237:203-9. 2007
    ..Our results suggest that MeHg inhibition of D2 activity might be involved in the inhibition of GH production in GH3 cells. Thus, D2 inhibition could be a novel mechanism involved in MeHg toxicity...
  29. ncbi request reprint Development of enzyme immunoassay for detection of DDT
    Masashi Hirano
    Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3 1 100 Tsukide, Kumamoto, Japan
    J Environ Sci Health B 43:44-9. 2008
    ..The results indicated that the developed EIA using this antibody could be a convenient and supplemental analytical tool for monitoring DDT...
  30. ncbi request reprint Methylmercury inhibits type II 5'-deiodinase activity in NB41A3 neuroblastoma cells
    Kouki Mori
    Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Miyagi, Japan
    Toxicol Lett 161:96-101. 2006
    ..Further our results suggest that T3 deficiency due to D2 inhibition in the brain may be involved in the neurotoxicity of MeHg...
  31. ncbi request reprint Susceptibility of metallothionein-null mice to the behavioral alterations caused by exposure to mercury vapor at human-relevant concentration
    Minoru Yoshida
    Department of Biochemistry, Division of Chemistry, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, Kawasaki 261 8511, Japan
    Toxicol Sci 80:69-73. 2004
    ....
  32. ncbi request reprint Estrogen and environmental estrogenic chemicals exert developmental effects on rat hypothalamic neurons and glias
    Makoto Yokosuka
    Laboratory for Animal Neuroscience, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
    Toxicol In Vitro 22:1-9. 2008
    ..Therefore, the present results demonstrated that not only E(2) but also the environmental estrogenic chemicals, NP and BPA, affect development of fetal rat hypothalamic cells in vitro...