Research Topics
| Chiho WatanabeSummaryAffiliation: University of Tokyo Country: Japan Publications
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Detail Information
Publications
Modification of mercury toxicity by selenium: practical importance?Chiho Watanabe
Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
Tohoku J Exp Med 196:71-7. 2002..Compared to the experimental findings, little evidence of the toxicological modification of MeHg by selenium was obtained in epidemiological studies...
Mutual interaction between nutritional status and chronic arsenic toxicity due to groundwater contamination in an area of Terai, lowland NepalMakhan Maharjan
Department of Human Ecology, School of International Health, Graduate School of Medicine, Universit of Tokyo, Tokyo, Japan
J Epidemiol Community Health 61:389-94. 2007..To reveal the inter-relationship between nutritional status and arsenic toxicity...- Effects of perinatal exposure to low-dose cadmium on thyroid hormone-related and sex hormone receptor gene expressions in brain of offspringHiromi Ishitobi
Department of Human Ecology, School of International Health, Graduate School of Medicine, The University of Tokyo, Japan
Neurotoxicology 28:790-7. 2007..Our study indicates that alteration in the gene expressions of RC3 and sex hormone receptors in the brain induced by perinatal Cd and MMI exposure might be one mechanism of developmental toxicity of Cd... - Gender difference in daily time and space use among Bangladeshi villagers under arsenic hazard: application of the compact spot-check methodRyutaro Ohtsuka
Department of Human Ecology, School of International Health, University of Tokyo, Hongo, Tokyo 113-0033, Japan
J Biosoc Sci 36:317-32. 2004..Discussion focuses on the advantages of the compact spot-check method and the possibility that males' larger energy expenditure and longer exposure to sunlight are responsible for their severer skin manifestations... - Arsenic contamination in drinking water and skin manifestations in lowland Nepal: the first community-based surveyMakhan Maharjan
Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Am J Trop Med Hyg 73:477-9. 2005..9%, which was comparable to those found by the same examiner in arsenic-contaminated areas in Bangladesh, and that males had prevalence a twice as high as females, which could not be explained by the difference in the exposure level... - Effects of low-dose perinatal cadmium exposure on tissue zinc and copper concentrations in neonatal mice and on the reproductive development of female offspringHiromi Ishitobi
Department of Human Ecology, School of International Health, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Toxicol Lett 159:38-46. 2005..These findings suggest that perinatal Cd exposure, even at low levels, affects the Zn and Cu concentrations of neonates and the reproductive functions of female offspring... - Dermatological and nutritional/growth effects among children living in arsenic-contaminated communities in rural BangladeshChiho Watanabe
Department of Human Ecology, Graduate School of Medicine, University of Tokyo
J Environ Sci Health A Tox Hazard Subst Environ Eng 42:1835-41. 2007.... - Pesticide usage and its association with health symptoms among farmers in rural villages in West Java, IndonesiaMakiko Sekiyama
Transdisciplinary Initiative for Global Sustainability, Integrated Research System for Sustainability Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
Environ Sci 14:23-33. 2007..Preventing such behaviors will be an effective method of reducing health problems among the subject farmers... - Water intake in an Asian population living in arsenic-contaminated areaChiho Watanabe
Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Toxicol Appl Pharmacol 198:272-82. 2004.... - Exposure assessment of phthalate esters in Japanese pregnant women by using urinary metabolite analysisYayoi Suzuki
Department of Environmental Studies, The University of Tokyo, Kashiwanoha 5 1 5, Kashiwa, Chiba, 270 8563, Japan
Environ Health Prev Med 14:180-7. 2009.... - Low-dose perinatal diethylstilbestrol exposure affected behaviors and hypothalamic estrogen receptor-alpha-positive cells in the mouseMika Tanaka
Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo, Tokyo, 113 0033, Japan
Neurotoxicol Teratol 26:261-9. 2004..The relationship between the increase in ER-IR cells and behavioral changes should be further examined... - Effects of arsenic on younger generationsChiho Watanabe
Department of Human Ecology, School of International Health, Graduate School of Medical Sciences, University of Tokyo, Japan
J Environ Sci Health A Tox Hazard Subst Environ Eng 38:129-39. 2003..Considering the public health importance of toxic effects imposed during the early life stages, it is clear that much more scientific efforts should be made to elucidate the possible effects of arsenic on the younger generations... - Skin manifestations of arsenicosis in two villages in BangladeshTakafumi Kadono
Department of Dermatology, Faculty of Medicine, School of International Health, University of Tokyo, Tokyo, Japan
Int J Dermatol 41:841-6. 2002..As skin manifestations are sensitive markers of arsenicosis, we examined the skin of adults and adolescents in two villages to elucidate the severity of arsenicosis... 
Behavioral and nutritional factors and geohelminth infection among two ethnic groups in the Terai region, NepalRajendra Prasad Parajuli
Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, 113 0033 Japan
Am J Hum Biol 21:98-104. 2009....- Arsenic in cooked rice in BangladeshMunjoo Bae
Department of Human Ecology, School of International Health, Graduate School of Medical Sciences, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-0033, Tokyo, Japan
Lancet 360:1839-40. 2002..The method of cooking and water used can affect the amount of arsenic in cooked rice, which will have implications for the assessment of the health risks of arsenic... - No difference in serum leptin concentrations between urban-dwelling Austronesians and Non-Austronesians in Papua New GuineaMika Tanaka
Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Am J Hum Biol 17:696-703. 2005..In conclusion, the NAN populations do not endogenously differ in leptin status from the AN populations, who have been recognized as a typical group with a "thrifty" genotype... - Severe toxicity and cyclooxygenase (COX)-2 mRNA increase by lithium in the neonatal mouse kidneyWataru Yoshioka
Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
J Toxicol Sci 34:519-25. 2009..The present results showed that the kidney of mouse neonates is vulnerable to lithium, and suggested the possibility that COX-2 upregulation is responsible for the severe renal toxicity including hydronephrosis... - [Estimation of intake level of di (2-ethyhexyl) phthalate (DEHP) in Japanese pregnant women based on measurement of concentrations of three urinary metabolites]Kayumi Fujimaki
Institute of Environmental Studies, University of Tokyo, Tokyo, Japan
Nippon Eiseigaku Zasshi 61:340-7. 2006.... - Impacts of dietary intake and helminth infection on diversity in growth among schoolchildren in rural south China: a four-year longitudinal studyHuan Zhou
Department of Human Ecology, School of International Health, Graduate School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
Am J Hum Biol 19:96-106. 2007..japonicum... - Twenty years' demographic change in sedentes and migrants of an international migrant-sending community in TongaShoko Fukuyama
Department of Human Ecology, School of International Health, University of Tokyo, Japan
J Biosoc Sci 41:77-87. 2009..If the current trends of international migration and fertility continue, the population of Kolovai will be reduced and its age composition will become cylinder-shaped in the near future... - Neurobehavioral changes in metallothionein-null mice prenatally exposed to mercury vaporMinoru Yoshida
Department of Biochemistry, Division of Chemistry, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, Kawasaki 261 8511, Japan
Toxicol Lett 155:361-8. 2005..From these results, we suggest that the increased susceptibility of MT-null females to behavioral changes caused by prenatal Hg0 exposure is due to a greater retention of mercury and lack of MT-I,-II in the brain... - The effects of gestational arsenic exposure and dietary selenium deficiency on selenium and selenoenzymes in maternal and fetal tissues in miceKaori Miyazaki
Department of Public Health, Division of Environmental Medicine, Gunma University Graduate School of Medicine, 3 39 22, Maebashi City, Gunma 371 8510, Japan
Toxicology 208:357-65. 2005.... - Arsenicosis in two villages in Terai, lowland NepalSk Akhtar Ahmad
Department of Occupational and Environmental Health, National Institute of Preventive and Social Medicine NIPSOM, Mohakhali, Dhaka 1212, Bangladesh
Environ Sci 11:179-88. 2004..3% of the identified patients. Only one patient had Bowen's disease. To our knowledge, the current study provides for the first time quantitative information regarding the arsenicosis patients in Nepal... - Behavioral changes in metallothionein-null mice after the cessation of long-term, low-level exposure to mercury vaporMinoru Yoshida
Department of Biochemistry, Division of Chemistry, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki 261-8511, Japan
Toxicol Lett 161:210-8. 2006..Finally, the MT-null mice seemed more susceptible to Hg0-induced neurotoxicity than the wild-type mice, confirming our previous results... - Gender differences in food and energy intake among adult villagers in northwestern Bangladesh: a food frequency questionnaire surveyNoriko Sudo
Department of Health Promotion and Research, National Institute of Public Health, 2 3 6 minami, Wako Shi, Saitama Prefecture, 351 0197, Japan
Int J Food Sci Nutr 55:499-509. 2004..8%) and females (37.8%), attributing to males' larger energy expenditure. Females' less-frequent consumption of nutritious foods and smaller energy intake were considered vulnerable to micronutrient deficiency... - Prevalence of arsenicosis in terai, NepalMakhan Maharjan
Environment and Public Health Organization, New Baneshwor, PO Box 4102, Kathmandu, Nepal
J Health Popul Nutr 24:246-52. 2006..Most patients were identified in the early or mild stage of the disease. They are expected to recover if further exposure to arsenic could be avoided by providing arsenic-safe drinking-water through intervention measures... - Effects of perinatal exposure to low doses of cadmium or methylmercury on thyroid hormone metabolism in metallothionein-deficient mouse neonatesKouki Mori
Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Sendai, Japan
Toxicology 228:77-84. 2006.... - Methylmercury inhibition of type II 5'-deiodinase activity resulting in a decrease in growth hormone production in GH3 cellsKouki Mori
Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
Toxicology 237:203-9. 2007..Our results suggest that MeHg inhibition of D2 activity might be involved in the inhibition of GH production in GH3 cells. Thus, D2 inhibition could be a novel mechanism involved in MeHg toxicity... - Development of enzyme immunoassay for detection of DDTMasashi Hirano
Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3 1 100 Tsukide, Kumamoto, Japan
J Environ Sci Health B 43:44-9. 2008..The results indicated that the developed EIA using this antibody could be a convenient and supplemental analytical tool for monitoring DDT... - Methylmercury inhibits type II 5'-deiodinase activity in NB41A3 neuroblastoma cellsKouki Mori
Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Miyagi, Japan
Toxicol Lett 161:96-101. 2006..Further our results suggest that T3 deficiency due to D2 inhibition in the brain may be involved in the neurotoxicity of MeHg... - Susceptibility of metallothionein-null mice to the behavioral alterations caused by exposure to mercury vapor at human-relevant concentrationMinoru Yoshida
Department of Biochemistry, Division of Chemistry, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, Kawasaki 261 8511, Japan
Toxicol Sci 80:69-73. 2004.... - Estrogen and environmental estrogenic chemicals exert developmental effects on rat hypothalamic neurons and gliasMakoto Yokosuka
Laboratory for Animal Neuroscience, Nippon Veterinary and Life Science University, 1 7 1 Kyonancho, Musashino, Tokyo 180 8602, Japan
Toxicol In Vitro 22:1-9. 2008..Therefore, the present results demonstrated that not only E(2) but also the environmental estrogenic chemicals, NP and BPA, affect development of fetal rat hypothalamic cells in vitro...