Y Ueda

Summary

Affiliation: University of Miyazaki
Country: Japan

Publications

  1. ncbi request reprint In vivo evaluation of the effect of zonisamide on the hippocampal redox state during kainic acid-induced seizure status in rats
    Yuto Ueda
    Department of Psychiatry, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki, Japan
    Neurochem Res 30:1117-21. 2005
  2. ncbi request reprint Protective role of pentobarbital pretreatment for NMDA-R activated lipid peroxidation is derived from the synergistic effect on endogenous anti-oxidant in the hippocampus of rats
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Neurosci Lett 417:46-9. 2007
  3. ncbi request reprint Functional role for redox in the epileptogenesis: molecular regulation of glutamate in the hippocampus of FeCl3-induced limbic epilepsy model
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Exp Brain Res 181:571-7. 2007
  4. ncbi request reprint [A new era of anti-epileptic drug (AED): expectation for a new-type medicine and combination therapy with existing AED]
    Yuto Ueda
    Nihon Yakurigaku Zasshi 129:116-8. 2007
  5. ncbi request reprint In vivo EPR estimation of bilateral hippocampal antioxidant ability of rats with epileptogenesis induced by amygdalar FeCl3 microinjection
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, University of Miyazaki, Miyazaki, Japan
    Epilepsia 48:1947-51. 2007
  6. ncbi request reprint In vivo activation of N-methyl-D-aspartate receptors generates free radicals and reduces antioxidant ability in the rat hippocampus: experimental protocol of in vivo ESR spectroscopy and microdialysis for redox status evaluation
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki 5200 Kihara, Kiyotake, Miyazaki, 889 1692, Japan
    Brain Res 1178:20-7. 2007
  7. doi request reprint Levetiracetam enhances endogenous antioxidant in the hippocampus of rats: in vivo evaluation by brain microdialysis combined with ESR spectroscopy
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Brain Res 1266:1-7. 2009
  8. ncbi request reprint Kinetics of extracellular nitroxide radical and glutamate levels in the hippocampus of conscious rats: cautionary note to the application of nitroxide radical on clinical arena
    Yuto Ueda
    Department of Psychiatry, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki 889 1692, Japan
    Neurochem Res 29:1695-701. 2004
  9. doi request reprint Hydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride
    Yuto Ueda
    Department of Clinical Neuroscience, Miyazaki University, Kiyotake, Miyazaki, Japan
    Neurochem Res 35:1510-5. 2010
  10. ncbi request reprint [Functional role of redox for neuronal disease]
    Y Ueda
    No To Hattatsu 40:103-8. 2008

Collaborators

Detail Information

Publications57

  1. ncbi request reprint In vivo evaluation of the effect of zonisamide on the hippocampal redox state during kainic acid-induced seizure status in rats
    Yuto Ueda
    Department of Psychiatry, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki, Japan
    Neurochem Res 30:1117-21. 2005
    ..This study is the first in vivo evaluation of the antioxidant ability of ZNS as neuroprotective role against the free radicals performed under the condition of freely moving rats during seizure status...
  2. ncbi request reprint Protective role of pentobarbital pretreatment for NMDA-R activated lipid peroxidation is derived from the synergistic effect on endogenous anti-oxidant in the hippocampus of rats
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Neurosci Lett 417:46-9. 2007
    ..Our findings, therefore, suggested that PBT anesthesia not only suppresses NMDA-R activated free radical generation but also synergistically enhances the increased basal endogenous anti-oxidant ability in the hippocampus...
  3. ncbi request reprint Functional role for redox in the epileptogenesis: molecular regulation of glutamate in the hippocampus of FeCl3-induced limbic epilepsy model
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Exp Brain Res 181:571-7. 2007
    ....
  4. ncbi request reprint [A new era of anti-epileptic drug (AED): expectation for a new-type medicine and combination therapy with existing AED]
    Yuto Ueda
    Nihon Yakurigaku Zasshi 129:116-8. 2007
  5. ncbi request reprint In vivo EPR estimation of bilateral hippocampal antioxidant ability of rats with epileptogenesis induced by amygdalar FeCl3 microinjection
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, University of Miyazaki, Miyazaki, Japan
    Epilepsia 48:1947-51. 2007
    ....
  6. ncbi request reprint In vivo activation of N-methyl-D-aspartate receptors generates free radicals and reduces antioxidant ability in the rat hippocampus: experimental protocol of in vivo ESR spectroscopy and microdialysis for redox status evaluation
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki 5200 Kihara, Kiyotake, Miyazaki, 889 1692, Japan
    Brain Res 1178:20-7. 2007
    ..These results indicated that NMDA-R activation caused the shift to oxidized condition of the redox state, which subsequently leads to neuron death in the hippocampus in the model of glutamate-associated neuronal disease...
  7. doi request reprint Levetiracetam enhances endogenous antioxidant in the hippocampus of rats: in vivo evaluation by brain microdialysis combined with ESR spectroscopy
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Brain Res 1266:1-7. 2009
    ....
  8. ncbi request reprint Kinetics of extracellular nitroxide radical and glutamate levels in the hippocampus of conscious rats: cautionary note to the application of nitroxide radical on clinical arena
    Yuto Ueda
    Department of Psychiatry, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki 889 1692, Japan
    Neurochem Res 29:1695-701. 2004
    ..More detailed studies on their possible toxicity of nitroxide radicals will be needed before the prospect of moving nitroxide from the experimental to the clinical arena when nitroxide radicals would be used for CNS disease in future...
  9. doi request reprint Hydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride
    Yuto Ueda
    Department of Clinical Neuroscience, Miyazaki University, Kiyotake, Miyazaki, Japan
    Neurochem Res 35:1510-5. 2010
    ..These results clarify the mechanism that CCH may exert antioxidant activity by significantly enhancing the basal endogenous antioxidant ability in the hippocampus through a synergistic effect with α-tocopherol and ascorbic acid...
  10. ncbi request reprint [Functional role of redox for neuronal disease]
    Y Ueda
    No To Hattatsu 40:103-8. 2008
  11. ncbi request reprint Generation of lipid radicals in the hippocampus of neonatal rats after acute hypoxic-ischemic brain damage
    Yuto Ueda
    Department of Psychiatry, Faculty of Medicine, University of Miyazaki, Kihara 5200, 889 1692 Miyazaki, Japan
    Exp Brain Res 169:117-21. 2006
    ..We hypothesize that an increased formation of lipid radicals may participate in the cascade of reactions leading to neuronal damage in the hippocampus following ischemic-hypoxic insult in neonatal rats...
  12. ncbi request reprint Effect of levetiracetam on molecular regulation of hippocampal glutamate and GABA transporters in rats with chronic seizures induced by amygdalar FeCl3 injection
    Yuto Ueda
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Brain Res 1151:55-61. 2007
    ..These observations together demonstrated the critical molecular mechanism of the anti-epileptic activity of LEV...
  13. ncbi request reprint Collapse of extracellular glutamate regulation during epileptogenesis: down-regulation and functional failure of glutamate transporter function in rats with chronic seizures induced by kainic acid
    Y Ueda
    Department of Psychiatry, Miyazaki Medical College, Miyazaki, Japan
    J Neurochem 76:892-900. 2001
    ....
  14. ncbi request reprint Kindling phenomena induced by the repeated short-term high potassium stimuli in the ventral hippocampus of rats: on-line monitoring of extracellular glutamate overflow
    Y Ueda
    Miyazaki Medical College, Department of Psychiatry, Miyazaki gun, Japan
    Exp Brain Res 135:199-203. 2000
    ....
  15. ncbi request reprint Molecular regulation of glutamate and GABA transporter proteins by valproic acid in rat hippocampus during epileptogenesis
    Y Ueda
    Department of Psychiatry, Miyazaki Medical College, Kiyotake, Japan
    Exp Brain Res 133:334-9. 2000
    ....
  16. ncbi request reprint Hippocampal gamma-aminobutyric acid transporter alterations following focal epileptogenesis induced in rat amygdala
    Y Ueda
    Department of Psychiatry, Miyazaki, Miyazaki Medical College, Miyazaki, Japan
    Brain Res Bull 52:357-61. 2000
    ..However, we propose that regulation of the GAT-3 subtype transporter was chronically elevated (at least 30 days), represents an effect of epileptogenesis induced by ferric ion injected into the amygdaloid body...
  17. ncbi request reprint An acute dysfunction of the glutamate transport activity has been shown to generate free radicals and suppress the anti-oxidant ability in the hippocampus of rats
    Keiko Nagatomo
    Section of Psychiatry, Department of Clinical Neuroscience, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, Japan
    Neurosci Res 57:477-80. 2007
    ..This study provides clear evidence for the mechanisms associated with neuronal disorder in relation to glutamate...
  18. ncbi request reprint Glutamate excess and free radical formation during and following kainic acid-induced status epilepticus
    Yuto Ueda
    Department of Psychiatry, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Exp Brain Res 147:219-26. 2002
    ..Further, we propose that the functional failure of glutamate transporters due to oxidative stress results in high levels of extracellular glutamate during sustained generalized seizures induced with KA...
  19. ncbi request reprint Sequential changes in glutamate transporter protein levels during Fe(3+)-induced epileptogenesis
    Y Ueda
    Department of Psychiatry, Miyazaki Medical College, Miyazaki gun, Kihara 5200, Kiyotake cho, Miyazaki, Japan
    Epilepsy Res 39:201-9. 2000
    ..The results suggest that iron-induced epileptogenesis involves alteration in glial glutamate transport that may lead to enhanced excitation within the hippocampus...
  20. ncbi request reprint Age-dependent changes in the hippocampal antioxidant ability of EL mice
    Mayuko Takaki
    Section of Integrative Physiology, Department of Medical Science, University of Miyazaki, Miyazaki 889 1692, Japan
    Neurosci Res 58:336-8. 2007
    ....
  21. ncbi request reprint Antioxidant ability and lipid peroxidation in the hippocampus with epileptogenesis induced by Fe3+ injection into the amygdaloid body of rats
    Yuto Ueda
    Department of Psychiatry, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki, Japan
    Neurochem Res 28:1895-900. 2003
    ..This study revealed that repetitive seizures resulted in the decreased hippocampal antioxidant ability with lipid peroxidation and explained the regional vulnerability to oxidative stress in the limbic system with epileptogenesis...
  22. ncbi request reprint Sequential changes in AMPA and NMDA protein levels during Fe(3+)-induced epileptogenesis
    T Doi
    Miyazaki Medical College, Department of Psychiatry, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan
    Brain Res Mol Brain Res 92:107-14. 2001
    ....
  23. ncbi request reprint Ability of water-soluble biosubstances to eliminate hydroxyl and superoxide radicals examined by spin-trapping ESR measurements: two-dimensional presentation of antioxidative ability
    Akira Nakajima
    Section of Obstetrics and Gynecology, Department of Reproductive and Developmental Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
    Biosci Biotechnol Biochem 77:324-31. 2013
    ..The biosubstances tested were assigned to five separate areas characterized by their functional groups on the diagram. The obtained ROS inhibitory diagram indicates the possibility for screening appropriate antioxidants...
  24. ncbi request reprint EPR evidence of hydroxyl radical generation as an initiator of lipid peroxidation in amyloid beta-protein-stimulated PC12 cells
    Yoshihito Hayashi
    Department of Psychiatry, Miyazaki Medical College, 5200 Kihara, Kiyotake cho, Miyazaki 889 1692, Japan
    Brain Res 1025:29-34. 2004
    ..These analyses showed cell damage induced by Abeta. This study provides EPR evidence that Abeta neurotoxicity is derived from hydrogen abstraction from polyunsaturated lipid acid by hydroxyl radical as a cause of lipid peroxidation...
  25. ncbi request reprint Nitric oxide and hydroxyl radicals initiate lipid peroxidation by NMDA receptor activation
    Yoshihito Hayashi
    Department of Psychiatry, Miyazaki Medical College, 5200 Kihara, Kiyotake cho, Miyazaki 889 1692, Japan
    Brain Res 941:107-12. 2002
    ..NO rather than from Fenton's reaction. This study verified that .OH generation from interactive reactions between .NO and O(2)(-) initiates NMDA-induced lipid peroxidation of PC12 cells...
  26. ncbi request reprint Increase in glutamate-aspartate transporter (GLAST) mRNA during kanamycin-induced cochlear insult in rats
    K Matsuda
    Department of Otorhinolaryngology, Miyazaki Medical College, Japan
    Hear Res 133:10-6. 1999
    ..Increased GLAST mRNA might play an important role in the prevention of the secondary death of spiral ganglion neurons from glutamate neurotoxicity...
  27. ncbi request reprint Cardiovascular changes induced by central hypertonic saline are accompanied by glutamate release in awake rats
    Q H Jin
    Department of Physiology, Miyazaki Medical College, Miyazaki 889 1692, Japan
    Am J Physiol Regul Integr Comp Physiol 281:R1224-31. 2001
    ..Our results show that local perfusion of the hypothalamic PVN region with hypertonic saline elicits a local release of glutamate, which may act via NMDA-type glutamate receptors to produce cardiovascular responses...
  28. doi request reprint Enhancement of in vivo antioxidant ability in the brain of rats fed tannin
    Akira Nakajima
    Section of Obstetrics and Gynecology, Department of Reproductive and Developmental Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889 1692, Japan
    Neurochem Res 38:1360-4. 2013
    ..In vitro study showed that MMT did not reduce PCAM directly but enhanced the reduction of PCAM by ascorbic acid. These results indicate that MMT is a potent antioxidant in vitro and in vivo...
  29. doi request reprint Novel δ1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex
    Shunsuke Tanahashi
    Department of Psychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, 2 174 Edobashi, Tsu, Mie 514 8507, Japan
    Neuropharmacology 62:2057-67. 2012
    ..1-receptor indirectly inhibited GABA release in NAc via activated dopaminergic transmission, while δ1-receptor indirectly enhanced GABA release in mPFC via activated glutamatergic transmission...
  30. ncbi request reprint A case report of refractory obsessive-compulsive disorder improved by risperidone augmentation of clomipramine treatment
    T Kawahara
    Department of Psychiatry, Miyazaki Medical College, Kiyotake, Japan
    Psychiatry Clin Neurosci 54:599-601. 2000
    ..Although the administration of anxiolytic drugs and/or clomipramine did not show curative effects, a combination of clomipramine and risperidone showed much greater effect in improving these symptoms...
  31. ncbi request reprint Mechanism of hexavalent chromium adsorption by persimmon tannin gel
    Akira Nakajima
    Department of Chemistry, Faculty of Medicine, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki 889 1692, Japan
    Water Res 38:2859-64. 2004
    ..Through the treatment of a Cr(VI) solution with the PT gel, chromium should be recovered as a Cr(IV)-tannin complex at pH 3 or a Cr(III) solution at pH 1 or lower pH region...
  32. ncbi request reprint Electron spin resonance study of copper biosorption by bacteria
    Akira Nakajima
    Faculty of Medicine, Department of Chemistry, Miyazaki Medical College, Kiyotake, Japan
    Water Res 36:2091-7. 2002
    ..The variation of spectral patterns among bacteria could explain as the change of ligand circumstances caused by the pH of the cell surface...
  33. ncbi request reprint Mechanism of gold adsorption by persimmon tannin gel
    Akira Nakajima
    Department of Chemistry, Faculty of Medicine, Miyazaki Medical College, Kiyotake, Miyazaki 889 1692, Japan
    Anal Sci 19:1075-7. 2003
    ..The gel could also adsorb colloidal Au(0) prepared independently. A model consisting of ligand exchange, Au(III) reduction to Au(0), and resulting Au(0) adsorption by PT gel was presented for the gold adsorption mechanism...
  34. ncbi request reprint Interleukin-6 protects PC12 cells from 4-hydroxynonenal-induced cytotoxicity by increasing intracellular glutathione levels
    Akira Nakajima
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Japan
    Free Radic Biol Med 32:1324-32. 2002
    ..These results suggest that IL-6 protects PC12 cells from HNE-induced cytotoxicity by increasing intracellular levels of GSH...
  35. ncbi request reprint Learning and memory in two different reward tasks in a radial arm maze in rats
    Jue He
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya 466 8560, Japan
    Behav Brain Res 134:139-48. 2002
    ..These results suggest that different strategies are used between the FPRT and VPRT but the hippocampus plays an important role in performance of rats trained for the VPRT as well as FPRT...
  36. pmc Involvement of BDNF receptor TrkB in spatial memory formation
    Makoto Mizuno
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya 466 8560, Japan
    Learn Mem 10:108-15. 2003
    ..The phosphorylation of Fyn and NR2B, but not TrkB, was diminished by PP2 treatment. Our findings suggest the importance of interaction between BDNF/TrkB signaling and NMDA receptors for spatial memory in the hippocampus...
  37. ncbi request reprint Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity
    Akira Nakajima
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466 8560, Japan
    J Neurosci 24:2212-25. 2004
    ....
  38. ncbi request reprint Effect of grinding and heating on Ni2+ uptake properties of waste paper sludge
    Vinay Kumar Jha
    Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, O Okayama, Meguro, Tokyo, Japan
    J Environ Manage 80:363-71. 2006
    ..The dry-milled and calcined at 600 degrees C sample showed the highest Ni2+ uptake (4.54 mmol/g) and an uptake rate of 3.5 micromol/(gmin)...
  39. ncbi request reprint An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor-alpha protects against methamphetamine-induced rewarding effects and sensitization
    Minae Niwa
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Biol Psychiatry 61:890-901. 2007
    ....
  40. ncbi request reprint Pharmacological action of nobiletin, a component of AURANTII NOBILIS PERICARPIUM with anti-dementia activity, and its application for development of functional foods
    Tohru Yamakuni
    Nihon Yakurigaku Zasshi 132:155-9. 2008
  41. pmc Expression of NR2B in cerebellar granule cells specifically facilitates effect of motor training on motor learning
    Jianwei Jiao
    Department of Psychiatry, University of Chicago, Chicago, Illinois, USA
    PLoS ONE 3:e1684. 2008
    ....
  42. doi request reprint Nobiletin, a citrus flavonoid, improves memory impairment and Abeta pathology in a transgenic mouse model of Alzheimer's disease
    Hiroshi Onozuka
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6 3 Aoba, Aramaki, Aoba ku, Sendai 980 8578, Japan
    J Pharmacol Exp Ther 326:739-44. 2008
    ..These findings suggest that this natural compound has potential to become a novel drug for fundamental treatment of AD...
  43. doi request reprint Utilization of steel-making slag for the uptake of ammonium and phosphate ions from aqueous solution
    Vinay Kumar Jha
    Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, Meguro, Tokyo, Japan
    J Hazard Mater 156:156-62. 2008
    ..91 and 0.65 micro mol/(g min), respectively. It was shown that heating slag composites prior to incorporation into wastewater treatment filters resulted in an increased degree of NH(4)(+) and PO(4)(3-) uptake...
  44. doi request reprint Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse
    Qian Chen
    Department of Psychiatry, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci Res 86:1615-25. 2008
    ..Most important, our results strongly suggest that to develop gamma-secretase inhibitors for the pharmacological treatment of AD may be not a reasonable strategy because antagonism of presenilin function may worsen neurodegeneration...
  45. ncbi request reprint Multi functional uptake behaviour of materials prepared by calcining waste paper sludge
    Vinay Kumar Jha
    Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, O Okayama, Meguro, Tokyo 152 8552, Japan
    J Environ Sci Health A Tox Hazard Subst Environ Eng 41:703-19. 2006
    ..From an economic point of view, paper sludge is the cheapest raw material for preparing adsorbents with high uptake ability for heavy metal, phosphate and ammonium ions...
  46. pmc Adult neurogenesis is functionally associated with AD-like neurodegeneration
    Qian Chen
    Department of Psychiatry, The University of Chicago, USA
    Neurobiol Dis 29:316-26. 2008
    ..Therefore, to enhance endogenous neurogenesis at early stages of neurodegeneration may be a valuable strategy to delay neurodegenerative progress...
  47. ncbi request reprint Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice
    Akira Nakajima
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980 8578, Japan
    J Pharmacol Sci 105:122-6. 2007
    ..These results suggest that nobiletin rescues OBX-induced cholinergic neurodegeneration, accompanied by improvement of impaired memory in OBX mice...
  48. ncbi request reprint Genetic approaches to the molecular/neuronal mechanisms underlying learning and memory in the mouse
    Akira Nakajima
    Department of Psychiatry, Committee on Neurobiology, The University of Chicago, Knapp Medical Research Center, Chicago, IL 60637, USA
    J Pharmacol Sci 99:1-5. 2005
    ..Studies using these techniques may eventually lead to the understanding of how new information is acquired and how learned information is memorized in the brain...
  49. ncbi request reprint Discriminative-stimulus effects of methamphetamine and morphine in rats are attenuated by cAMP-related compounds
    Yijin Yan
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466 8560, Japan
    Behav Brain Res 173:39-46. 2006
    ..These findings suggest that the cAMP signaling cascade may play a key role in the discriminative-stimulus effects of METH and morphine and may be a potential target for the development of therapeutics to counter drugs of abuse...
  50. ncbi request reprint Simultaneous uptake of ammonium and phosphate ions by compounds prepared from paper sludge ash
    Kiyoshi Okada
    Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, O Okayama, Meguro, Tokyo 152 8552, Japan
    J Hazard Mater 141:622-9. 2007
    ....
  51. ncbi request reprint Simultaneous uptake of Ni2+, NH4+ and PO4(3-) by amorphous CaO-Al2O3-SiO2 compounds
    Kiyoshi Okada
    Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, O Okayama, Meguro, Tokyo 152 8552, Japan
    J Colloid Interface Sci 305:229-38. 2007
    ..The optimum uptake properties of the C-A-S can thus be controlled by adjusting the chemical compositions and heating conditions under which the samples are prepared...
  52. ncbi request reprint Tumor necrosis factor-alpha and its inducer inhibit morphine-induced rewarding effects and sensitization
    Minae Niwa
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, 65 Tsuruma cho, Showa Ku, Nagoya 466 8560, Japan
    Biol Psychiatry 62:658-68. 2007
    ..In this study, we investigated the effects of TNF-alpha or Leu-Ile on morphine (MOR)-induced rewarding effects and sensitization...
  53. ncbi request reprint Fos expression associated with the discriminative stimulus effects of methamphetamine in rats
    Nan Zeng
    Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466 8560, Japan
    Ann N Y Acad Sci 1025:236-41. 2004
    ..These results suggest that the VTA and the NAc play an important role in the discriminative stimulus effects of methamphetamine...
  54. ncbi request reprint Purification, characterization, and gene cloning of glycerol dehydrogenase from Hansenula ofunaensis, and its expression for production of optically active diol
    Keiko Yamada-Onodera
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916 5 Takayama, Ikoma 630 0192, Japan
    J Biosci Bioeng 102:545-51. 2006
    ..Glycerol dehydrogenase from H. ofunaensis could be useful for the production of long-chain optically active secondary alcohols...
  55. ncbi request reprint Nobiletin, a citrus flavonoid, reverses learning impairment associated with N-methyl-D-aspartate receptor antagonism by activation of extracellular signal-regulated kinase signaling
    Akira Nakajima
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6 6 11 404 Aoba, Aramaki, Aoba ku, Sendai 980 8579, Japan
    J Pharmacol Exp Ther 321:784-90. 2007
    ....
  56. ncbi request reprint Design of a photocatalyst for bromate decomposition: surface modification of TiO2 by pseudo-boehmite
    Hiroshi Noguchi
    Research Center for Advanced Science and Technology, The University of Tokyo, 4 6 1, Komaba, Meguro ku, Tokyo 153 8904, Japan
    Environ Sci Technol 37:153-7. 2003
    ..This increase is explained by an increase in the amount of adsorbed BrO3- on the photocatalyst surface...
  57. pmc Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse
    Qian Chen
    Department of Psychiatry, University of Chicago, 924 East 57th Street, Chicago, IL 60637, USA
    Proc Natl Acad Sci U S A 103:3881-6. 2006
    ..In addition, our study has validated a robust genetic anxiety model in the mouse in terms of their face, constructive, and predictive validity...