Naoyuki Tsuchiya

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus
    N Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan 113 0033
    Genes Immun 1:501-3. 2000
  2. ncbi request reprint Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility
    Chieko Kyogoku
    University of Tokyo, Tokyo, Japan
    Arthritis Rheum 46:1242-54. 2002
  3. pmc Serum biomarker analysis of collagen disease patients with acute-onset diffuse interstitial lung disease
    Shomi Oka
    Clinical Research Center for Allergy and Rheumatology, Sagamihara Hospital, National Hospital Organization, 18 1 Sakuradai, Minami Ku, Sagamihara, Kanagawa, 252 0392, Japan
    BMC Immunol 14:9. 2013
  4. pmc TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study
    Aya Kawasaki
    Molecular and Genetic Epidemiology Laboratory, Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba 305 8575, Japan
    Arthritis Res Ther 13:R41. 2011
  5. ncbi request reprint Analysis of the association of HLA-DRB1, TNFalpha promoter and TNFR2 (TNFRSF1B) polymorphisms with SLE using transmission disequilibrium test
    N Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Genes Immun 2:317-22. 2001
  6. ncbi request reprint Role of Fc gamma receptor IIb polymorphism in the genetic background of systemic lupus erythematosus: insights from Asia
    Naoyuki Tsuchiya
    Graduate School of Medicine, The University of Tokyo, Department of Human Genetics, Tokyo 113 0033, Japan
    Autoimmunity 38:347-52. 2005
  7. ncbi request reprint Association of HLA-DRB1*0901-DQB1*0303 haplotype with microscopic polyangiitis in Japanese
    N Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Hongo, Tokyo, Japan
    Genes Immun 7:81-4. 2006
  8. ncbi request reprint Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis
    Naoyuki Tsuchiya
    Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Arthritis Rheum 50:4002-7. 2004
  9. ncbi request reprint Genetic background of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis: association of HLA-DRB1*0901 with microscopic polyangiitis
    Naoyuki Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Rheumatol 30:1534-40. 2003
  10. doi request reprint Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: support for a crucial role of intron 1 polymorphisms
    Aya Kawasaki
    University of Tsukuba, Tsukuba, Japan
    Arthritis Rheum 58:826-34. 2008

Detail Information

Publications50

  1. ncbi request reprint New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus
    N Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan 113 0033
    Genes Immun 1:501-3. 2000
    ..Two other cSNPs, nt543 (C-->T) (P181P) and nt694 (G-->A) (E232K), were not significantly associated with SLE. Thus, among the non-synonymous cSNPs, only nt587 (T-->G) (M196R) was found to be significantly associated with SLE in Japanese...
  2. ncbi request reprint Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility
    Chieko Kyogoku
    University of Tokyo, Tokyo, Japan
    Arthritis Rheum 46:1242-54. 2002
    ....
  3. pmc Serum biomarker analysis of collagen disease patients with acute-onset diffuse interstitial lung disease
    Shomi Oka
    Clinical Research Center for Allergy and Rheumatology, Sagamihara Hospital, National Hospital Organization, 18 1 Sakuradai, Minami Ku, Sagamihara, Kanagawa, 252 0392, Japan
    BMC Immunol 14:9. 2013
    ..The prognosis of acute-onset diffuse ILD (AoDILD) occurring in collagen disease patients is very poor. Here, we investigated serum biomarker profiles of AoDILD to find markers predicting outcome in patients with collagen diseases...
  4. pmc TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study
    Aya Kawasaki
    Molecular and Genetic Epidemiology Laboratory, Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba 305 8575, Japan
    Arthritis Res Ther 13:R41. 2011
    ..To test whether additional polymorphisms contribute to SLE in Japanese, we systematically analyzed the association of TLR7 with SLE in a Japanese female population...
  5. ncbi request reprint Analysis of the association of HLA-DRB1, TNFalpha promoter and TNFR2 (TNFRSF1B) polymorphisms with SLE using transmission disequilibrium test
    N Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Genes Immun 2:317-22. 2001
    ..In addition, a possible disease-protective role for TNF haplotype coding for -1031C, -863A, -857C was suggested...
  6. ncbi request reprint Role of Fc gamma receptor IIb polymorphism in the genetic background of systemic lupus erythematosus: insights from Asia
    Naoyuki Tsuchiya
    Graduate School of Medicine, The University of Tokyo, Department of Human Genetics, Tokyo 113 0033, Japan
    Autoimmunity 38:347-52. 2005
    ..These results indicate that FCGR2B is a susceptibility gene to SLE in the context of a genetic background, both in humans and mice...
  7. ncbi request reprint Association of HLA-DRB1*0901-DQB1*0303 haplotype with microscopic polyangiitis in Japanese
    N Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Hongo, Tokyo, Japan
    Genes Immun 7:81-4. 2006
    ....
  8. ncbi request reprint Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis
    Naoyuki Tsuchiya
    Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Arthritis Rheum 50:4002-7. 2004
    ..In this study, we examined whether CD19 polymorphisms are associated with genetic susceptibility to SSc...
  9. ncbi request reprint Genetic background of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis: association of HLA-DRB1*0901 with microscopic polyangiitis
    Naoyuki Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Rheumatol 30:1534-40. 2003
    ..Little is known on the genetic background of AAV in Japanese patients mainly because of the difficulty in collecting a sufficient number of samples for the genetics study...
  10. doi request reprint Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: support for a crucial role of intron 1 polymorphisms
    Aya Kawasaki
    University of Tsukuba, Tsukuba, Japan
    Arthritis Rheum 58:826-34. 2008
    ..To determine whether the IRF5 gene, which encodes interferon regulatory factor 5, is associated with systemic lupus erythematosus (SLE) in a Japanese population...
  11. pmc Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region
    Aya Kawasaki
    Molecular and Genetic Epidemiology Laboratory, Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba 305 8575, Japan
    Arthritis Res Ther 10:R113. 2008
    ..To accomplish these aims, we carried out a comprehensive association analysis of 52 tag single nucleotide polymorphisms (SNPs) encompassing the STAT1-STAT4 region...
  12. doi request reprint Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population
    Ikue Ito
    Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan
    Arthritis Rheum 60:1845-50. 2009
    ..We undertook the present study to determine whether IRF5 polymorphisms are also associated with a predisposition to SSc in Japanese...
  13. pmc Association of TNFAIP3 polymorphism with susceptibility to systemic lupus erythematosus in a Japanese population
    Aya Kawasaki
    Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba 305 8575, Japan
    J Biomed Biotechnol 2010:207578. 2010
    ..013). These results indicated that TNFAIP3 is a susceptibility gene to SLE both in the Caucasian and Asian populations...
  14. doi request reprint Association of the FAM167A-BLK region with systemic sclerosis
    Ikue Ito
    University of Tsukuba, Tsukuba, Japan
    Arthritis Rheum 62:890-5. 2010
    ..We undertook the current study to examine whether the FAM167A-BLK region is also associated with susceptibility to systemic sclerosis (SSc)...
  15. pmc Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study
    Aya Kawasaki
    Molecular and Genetic Epidemiology Laboratory, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8575, Japan
    Arthritis Res Ther 12:R174. 2010
    ..In this study, we investigated whether the association of TNIP1 with SLE was replicated in a Japanese population. In addition, association of TNIP1 with RA was also examined...
  16. ncbi request reprint Association of IRF5, STAT4 and BLK with systemic lupus erythematosus and other rheumatic diseases
    Naoyuki Tsuchiya
    Molecular and Genetic Epidemiology Laboratory, Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba
    Nihon Rinsho Meneki Gakkai Kaishi 33:57-65. 2010
    ..Thus, a substantial proportion of susceptibility genes are shared by multiple autoimmune rheumatic diseases...
  17. doi request reprint Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population
    Ikue Ito
    University of Tsukuba, Tsukuba, Japan
    Arthritis Rheum 60:553-8. 2009
    ..The purpose of this study was to evaluate the significance of this region in the genetic background of Japanese patients with SLE...
  18. ncbi request reprint FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling
    Hajime Kono
    Department of Allergy and Rheumatology, Faculty of Medicine, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Tokyo 113 8655, Japan
    Hum Mol Genet 14:2881-92. 2005
    ..Collectively, the present findings indicate that the Ile232Thr substitution affects the localization and function of FcgammaRIIB and that the molecular mechanism may link the polymorphism and susceptibility to SLE...
  19. ncbi request reprint Association of killer cell immunoglobulin-like receptor genotypes with microscopic polyangiitis
    Risa Miyashita
    University of Tokyo, Hongo, Tokyo, Japan
    Arthritis Rheum 54:992-7. 2006
    ..In this study, we examined possible associations of the presence or absence of KIR loci with a genetic predisposition to MPA...
  20. ncbi request reprint Molecular genetic analyses of human NKG2C (KLRC2) gene deletion
    Risa Miyashita
    Department of Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo 113 0033, Japan
    Int Immunol 16:163-8. 2004
    ..These results indicated that NKG2C deletion is commonly present in Japanese and Dutch, suggesting that NKG2C is not essential for survival and reproduction, and is not associated with rheumatic diseases...
  21. ncbi request reprint CD72 polymorphisms associated with alternative splicing modify susceptibility to human systemic lupus erythematosus through epistatic interaction with FCGR2B
    Yuki Hitomi
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Japan
    Hum Mol Genet 13:2907-17. 2004
    ..These results indicated that the presence of CD72-*2 allele decreases risk for human SLE conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72...
  22. doi request reprint IFNGR1 polymorphisms in Thai malaria patients
    Izumi Naka
    Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305 8575, Japan
    Infect Genet Evol 9:1406-9. 2009
    ..These data also provide useful information for future genetic studies of IFNG polymorphisms in Thai patients...
  23. ncbi request reprint Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer
    Takeshi Tsuchiya
    Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Bunkyo ku, Japan
    Cancer Sci 96:784-90. 2005
    ..Id should be considered an ideal target for the treatment and prevention of gastric cancer, and RNA interference is an attractive and promising strategy to achieve it...
  24. doi request reprint Cumulative association of eight susceptibility genes with systemic lupus erythematosus in a Japanese female population
    Minori Koga
    Molecular and Genetic Epidemiology Laboratory, Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan
    J Hum Genet 56:503-7. 2011
    ..30, CI 1.09-4.83, P=0.025). This study suggested that the cumulative number of risk alleles may efficiently distinguish groups with high and low genetic predisposition to SLE and its severe manifestation...
  25. ncbi request reprint Variations in immune response genes and their associations with multifactorial immune disorders
    Naoyuki Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Immunol Rev 190:169-81. 2002
    ..At the same time, our observations may indicate that the 'classical' candidate gene approach will remain a strong alternative, even in the age of 'post genome-sequence'...
  26. ncbi request reprint Association of Fcgamma receptor IIA, but not IIB and IIIA, polymorphisms with systemic lupus erythematosus: A family-based association study in Caucasians
    Chieko Kyogoku
    University of Tokyo, Tokyo, Japan
    Arthritis Rheum 50:671-3. 2004
  27. ncbi request reprint Role of B cell inhibitory receptor polymorphisms in systemic lupus erythematosus: a negative times a negative makes a positive
    Naoyuki Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo Bunkyo ku, Tokyo, 113 0033, Japan
    J Hum Genet 51:741-50. 2006
    ..These observations emphasize the need to understand human immune system diversity if we are to improve our understanding of the pathogenesis of autoimmune diseases...
  28. pmc A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population
    Izumi Naka
    Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan
    Malar J 8:290. 2009
    ..An IL12B promoter allele, CTCTAA, at rs17860508 has been reported to be associated with susceptibility to cerebral malaria in African populations. However, this association has not so far been replicated in non-African populations...
  29. doi request reprint Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus
    Koki Hikami
    University of Tsukuba, Tsukuba, Japan
    Arthritis Rheum 63:755-63. 2011
    ..In view of the significance of the type I interferon pathway in systemic lupus erythematosus (SLE), this study was undertaken to investigate a possible association between SPI1 polymorphisms and SLE...
  30. pmc Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria
    Izumi Naka
    Doctoral Programme in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan
    Malar J 8:232. 2009
    ....
  31. doi request reprint Association of IL-10 receptor 2 (IL10RB) SNP with systemic sclerosis
    Koki Hikami
    Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8575, Japan
    Biochem Biophys Res Commun 373:403-7. 2008
    ..0019). Serum IL-10 level was significantly associated with the number of rs2834167A allele (P=0.007). These findings suggested that signaling through IL-10R2 may play a causative role in dcSSc...
  32. ncbi request reprint Immunogenetic features in 120 Japanese patients with idiopathic inflammatory myopathy
    Takefumi Furuya
    Institute of Rheumatology and Department of Neurology, Tokyo Women s Medical University, Tokyo, Japan
    J Rheumatol 31:1768-74. 2004
    ..To examine the role of HLA-DRB1 and tumor necrosis factor (TNF) promoter genotypes in the development and the autoantibody profiles of idiopathic inflammatory myopathy (IIM) in Japanese patients...
  33. ncbi request reprint The human histocompatibility leukocyte antigen (HLA) haplotype is associated with the onset of postherpetic neuralgia after herpes zoster
    Masako Sato-Takeda
    Department of Anesthesiology and Pain Relief Center, University of Tokyo Hospital, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Pain 110:329-36. 2004
    ..These results suggest that the HLA-A*3303-B*4403-DRB1*1302 haplotype plays an important role in the development of PHN after herpes zoster, but not in the onset of herpes zoster...
  34. ncbi request reprint Effects of down-regulating the Id genes in human colorectal cancer cells on early steps of haematogenous metastasis
    Yurai Okaji
    Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Eur J Cancer 42:668-73. 2006
    ..The present results indicate important roles of Id genes in tumour cells during early steps of haematogenous metastasis and suggest dual effects from their therapeutic inhibition...
  35. ncbi request reprint [Current studies on susceptibility genes in rheumatoid arthritis]
    Naoyuki Tsuchiya
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo
    Nihon Rinsho 63:111-6. 2005
  36. ncbi request reprint Comparative study of the haplotype structure and linkage disequilibrium of chromosome 1p36.2 region in the Korean and Japanese populations
    Tamao Akesaka
    Department of Human Genetics, University of Tokyo, Tokyo, Japan
    J Hum Genet 49:603-9. 2004
    ..Significant difference in LD strength was present near the TNFR2 region between the Japanese and Korean populations...
  37. doi request reprint The impact of natural selection on an ABCC11 SNP determining earwax type
    Jun Ohashi
    Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Mol Biol Evol 28:849-57. 2011
    ..Our results provide a striking example of how local adaptation has played a significant role in the diversification of human traits...
  38. pmc Association of ADAMTS13 polymorphism with cerebral malaria
    Sirima Kraisin
    Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan
    Malar J 10:366. 2011
    ....
  39. ncbi request reprint Diversity of human immune system multigene families and its implication in the genetic background of rheumatic diseases
    Naoyuki Tsuchiya
    Doctoral Program in Social and Environmental Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8575, Japan
    Curr Med Chem 14:431-9. 2007
    ..These results emphasize the role of multigene families in the diversity of human immune response and susceptibility to diseases...
  40. ncbi request reprint A novel method for isolation of endothelial cells and macrophages from murine tumors based on Ac-LDL uptake and CD16 expression
    Yurai Okaji
    Department of Surgical Oncology, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Immunol Methods 295:183-93. 2004
    ..The present method is hoped to be useful for the evaluation of tumor angiogenesis and antitumor immunity...
  41. pmc Human CD72 splicing isoform responsible for resistance to systemic lupus erythematosus regulates serum immunoglobulin level and is localized in endoplasmic reticulum
    Yuki Hitomi
    Laboratory of Immunology, School of Biomedical Science, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8510, Japan
    BMC Immunol 13:72. 2012
    ..The human CD72 locus generates a splicing isoform that lacks exon 8 (CD72Δex8) as well as full-length CD72 (CD72fl), and the CD72 polymorphism regulates exon 8 skipping...
  42. doi request reprint The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders
    Takuro Furusawa
    Asian Studies Network ASNET, Division for International Relations, The University of Tokyo, Tokyo, Japan
    Hum Genet 127:287-94. 2010
    ..The 223Q allele was widely found among the AN-speaking study subjects, thus suggesting that the LEPR Q223R polymorphism is one of the factors contributing to the high prevalence of obesity in the Pacific Island populations...
  43. ncbi request reprint Crucial role of inhibitor of DNA binding/differentiation in the vascular endothelial growth factor-induced activation and angiogenic processes of human endothelial cells
    Daisuke Sakurai
    Department of Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Immunol 173:5801-9. 2004
    ..Based on these findings, it was proposed that inhibition of expression and/or function of Id1 and Id3 may potentially be of therapeutic value for conditions associated with pathological angiogenesis...
  44. ncbi request reprint Variations in the human Th2-specific chemokine TARC gene
    Takashi Sekiya
    Department of Allergy and Rheumatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Immunogenetics 54:742-5. 2003
    ..However, when the genotypes at the SNP site were determined for 158 healthy individuals, 105 patients with BA and 148 patients with AD, we observed no significant association of the SNP with susceptibility to BA or AD...
  45. ncbi request reprint Evaluation of microsatellite markers in association studies: a search for an immune-related susceptibility gene in sarcoidosis
    Goh Tanaka
    Department of Respiratory Diseases, Research Institute, International Medical Center of Japan, Tokyo 162 8655, Japan
    Immunogenetics 56:861-70. 2005
    ....
  46. ncbi request reprint TNFR2 position 196 polymorphism in Japanese patients with rheumatoid arthritis: comment on the article by Dieudé et al
    Chieko Kyogoku
    Arthritis Rheum 48:273-4. 2003
  47. ncbi request reprint BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex
    Hidenori Hase
    Division of Immunology, Institute for Medical Science, and Department of Pathology, Dokkyo University School of Medicine, Mibu, Tochigi 321 0293, Japan
    Blood 103:2257-65. 2004
    ....
  48. ncbi request reprint Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis
    Kimiko Kuroki
    Division of Structural Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    Hum Mol Genet 14:2469-80. 2005
    ..In addition, these observations suggested that the polymorphisms of LILR family members may be substantially involved in the diversity of human immune responses...
  49. ncbi request reprint Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: an international meta-analysis
    Fotini B Karassa
    University of Ioannina School of Medicine, Ioannina, Greece
    Arthritis Rheum 48:1930-8. 2003
    ..To assess the impact of the FcgammaRIIA-R/H131 polymorphism on the risk for antiphospholipid syndrome (APS), both primary and secondary to systemic lupus erythematosus (SLE)...
  50. ncbi request reprint Association of CYP17 with HLA-B27-negative seronegative spondyloarthropathy in Japanese males
    Kanji Mori
    Department of Orthopaedic Surgery, Shiga University of Medical Science, Tsukinowa cho, Seta, Otsu, Shiga, Japan
    Am J Med Genet A 130:169-71. 2004
    ..Haplotype analysis did not demonstrate more significant association. The CYP17 SNP is associated with SNSA in HLA-B27-negative Japanese males...