Ryu Takizawa

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint Multiple-time replicability of near-infrared spectroscopy recording during prefrontal activation task in healthy men
    Toshiaki Kono
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Neurosci Res 57:504-12. 2007
  2. doi request reprint Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia
    Ryu Takizawa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 33:491-8. 2009
  3. ncbi request reprint Reduced frontopolar activation during verbal fluency task in schizophrenia: a multi-channel near-infrared spectroscopy study
    Ryu Takizawa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Schizophr Res 99:250-62. 2008
  4. pmc Association between catechol-O-methyltrasferase Val108/158Met genotype and prefrontal hemodynamic response in schizophrenia
    Ryu Takizawa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    PLoS ONE 4:e5495. 2009
  5. ncbi request reprint Decreased prefrontal activation during letter fluency task in adults with pervasive developmental disorders: a near-infrared spectroscopy study
    Hitoshi Kuwabara
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Behav Brain Res 172:272-7. 2006
  6. doi request reprint Association of decreased prefrontal hemodynamic response during a verbal fluency task with EGR3 gene polymorphism in patients with schizophrenia and in healthy individuals
    Yukika Nishimura
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Department of Youth Mental Health, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Electronic address
    Neuroimage 85:527-34. 2014
  7. doi request reprint Different hemodynamic response patterns in the prefrontal cortical sub-regions according to the clinical stages of psychosis
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 132:54-61. 2011
  8. doi request reprint Gender difference in right lateral prefrontal hemodynamic response while viewing fearful faces: a multi-channel near-infrared spectroscopy study
    Kohei Marumo
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Neurosci Res 63:89-94. 2009
  9. doi request reprint Association between severe dorsolateral prefrontal dysfunction during random number generation and earlier onset in schizophrenia
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Clin Neurophysiol 122:1533-40. 2011
  10. doi request reprint Potential biomarker of subjective quality of life: Prefrontal activation measurement by near-infrared spectroscopy
    Yoshihiro Satomura
    a Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo Study Site, Bunkyo ku, Tokyo, Japan
    Soc Neurosci 9:63-73. 2014

Detail Information

Publications20

  1. ncbi request reprint Multiple-time replicability of near-infrared spectroscopy recording during prefrontal activation task in healthy men
    Toshiaki Kono
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Neurosci Res 57:504-12. 2007
    ..Further studies using different conditions or assessing sensitivity to longitudinal changes following interventions are necessary...
  2. doi request reprint Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia
    Ryu Takizawa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 33:491-8. 2009
    ..Our findings also suggest that the prefrontal hemodynamic response assessed by noninvasive and less demanding NIRS is a useful intermediate phenotype for translational research in schizophrenia...
  3. ncbi request reprint Reduced frontopolar activation during verbal fluency task in schizophrenia: a multi-channel near-infrared spectroscopy study
    Ryu Takizawa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Schizophr Res 99:250-62. 2008
    ....
  4. pmc Association between catechol-O-methyltrasferase Val108/158Met genotype and prefrontal hemodynamic response in schizophrenia
    Ryu Takizawa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    PLoS ONE 4:e5495. 2009
    ..Here, we investigated spatiotemporal characteristics of the association between prefrontal hemodynamic activation and the COMT genotype using a noninvasive neuroimaging technique, near-infrared spectroscopy (NIRS)...
  5. ncbi request reprint Decreased prefrontal activation during letter fluency task in adults with pervasive developmental disorders: a near-infrared spectroscopy study
    Hitoshi Kuwabara
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Behav Brain Res 172:272-7. 2006
    ..The present results may be also potentially useful for applying NIRS to clinical settings of child psychiatry...
  6. doi request reprint Association of decreased prefrontal hemodynamic response during a verbal fluency task with EGR3 gene polymorphism in patients with schizophrenia and in healthy individuals
    Yukika Nishimura
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Department of Youth Mental Health, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Electronic address
    Neuroimage 85:527-34. 2014
    ..Genetic variation in EGR3 may affect prefrontal function through neurodevelopment. This study illustrates the usefulness of NIRS in imaging genetics investigations on psychiatric disorders. ..
  7. doi request reprint Different hemodynamic response patterns in the prefrontal cortical sub-regions according to the clinical stages of psychosis
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 132:54-61. 2011
    ..Multichannel near-infrared spectroscopy (NIRS), which can easily and noninvasively measure hemodynamics over the prefrontal cortex, is a candidate instrument for clinical use...
  8. doi request reprint Gender difference in right lateral prefrontal hemodynamic response while viewing fearful faces: a multi-channel near-infrared spectroscopy study
    Kohei Marumo
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Neurosci Res 63:89-94. 2009
    ..This observation may help to establish NIRS as a clinical tool for monitoring prefrontal function on an individual basis...
  9. doi request reprint Association between severe dorsolateral prefrontal dysfunction during random number generation and earlier onset in schizophrenia
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Clin Neurophysiol 122:1533-40. 2011
    ..Age at onset is a major factor for predicting social outcome in schizophrenia. In clinical settings, we need an objective assessment tool for evaluating prefrontal function and social outcome...
  10. doi request reprint Potential biomarker of subjective quality of life: Prefrontal activation measurement by near-infrared spectroscopy
    Yoshihiro Satomura
    a Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo Study Site, Bunkyo ku, Tokyo, Japan
    Soc Neurosci 9:63-73. 2014
    ..These findings suggest that subjective QOL has possible involvement in prefrontal function and that NIRS potentially plays a role as a biological marker of subjective QOL. ..
  11. doi request reprint Genetic influences on prefrontal activation during a verbal fluency task in adults: A twin study based on multichannel near-infrared spectroscopy
    Eisuke Sakakibara
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan 2 Department of Psychiatry, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan Electronic address
    Neuroimage 85:508-17. 2014
    ..This implies that the prefrontal hemodynamic dysfunction observed during an executive function task measured by NIRS may be an efficient endophenotype for large-scale imaging genetic studies in psychiatric disorders. ..
  12. pmc Developmental changes of prefrontal activation in humans: a near-infrared spectroscopy study of preschool children and adults
    Yuki Kawakubo
    Department of Child Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    PLoS ONE 6:e25944. 2011
    ..Although the developmental change of the frontopolar PFC was independent of gender from childhood to adolescence, in adulthood a gender difference was shown...
  13. doi request reprint Distinct effects of duration of untreated psychosis on brain cortical activities in different treatment phases of schizophrenia: A multi-channel near-infrared spectroscopy study
    Po Han Chou
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, 113 8655, Japan Department of Psychiatry, Taichung Veterans General Hospital, Taichung City, 40705, Taiwan
    Prog Neuropsychopharmacol Biol Psychiatry 49:63-9. 2014
    ..In the present study, we used near-infrared spectroscopy (NIRS) to investigate the influence of DUP on brain functions during a verbal fluency test (VFT) in patients with schizophrenia...
  14. doi request reprint Functional abnormalities in the left ventrolateral prefrontal cortex during a semantic fluency task, and their association with thought disorder in patients with schizophrenia
    Kohei Marumo
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo 113 8655, Japan
    Neuroimage 85:518-26. 2014
    ....
  15. doi request reprint Differential spatiotemporal characteristics of the prefrontal hemodynamic response and their association with functional impairment in schizophrenia and major depression
    Masaru Kinou
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 150:459-67. 2013
    ..These results suggest a differential brain pathophysiology between SZ and MDD. Future large-scale studies are needed to determine the practical applicability of these findings for clinical diagnosis and evaluation. ..
  16. doi request reprint A multimodal approach to investigate biomarkers for psychosis in a clinical setting: the integrative neuroimaging studies in schizophrenia targeting for early intervention and prevention (IN-STEP) project
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 143:116-24. 2013
    ..0%, and 35.3% (at 6, 12, and 24months, respectively). Through this research project, we expect to clarify the pathophysiological features around the onset of psychosis and improve the prognosis of psychosis through clinical application...
  17. doi request reprint Phonological fluency is uniquely impaired in Japanese-speaking schizophrenia patients: confirmation study
    Motomu Suga
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Psychiatry Clin Neurosci 65:672-5. 2011
    ....
  18. doi request reprint Reduced but broader prefrontal activity in patients with schizophrenia during n-back working memory tasks: a multi-channel near-infrared spectroscopy study
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    J Psychiatr Res 47:1240-6. 2013
    ....
  19. doi request reprint Neuroimaging-aided differential diagnosis of the depressive state
    Ryu Takizawa
    Department of Neuropsychiatry, The University of Tokyo Graduate School of Medicine, Tokyo 113 8655, Japan
    Neuroimage 85:498-507. 2014
    ..Potential confounding effects of clinical (e.g., age, sex) and systemic (e.g., autonomic nervous system indices) variables on brain signals will need to be clarified to improve classification accuracy. ..
  20. doi request reprint Comprehensive DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia
    Masaki Nishioka
    Department of Molecular Psychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Hum Genet 58:91-7. 2013
    ..Our results indicate the site-specific epigenetic alterations in patients with FESZ...