Research Topics
Species | Ryu TakizawaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Detail Information
Publications
Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophreniaRyu Takizawa
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Japan
Prog Neuropsychopharmacol Biol Psychiatry 33:491-8. 2009..Our findings also suggest that the prefrontal hemodynamic response assessed by noninvasive and less demanding NIRS is a useful intermediate phenotype for translational research in schizophrenia...
Reduced frontopolar activation during verbal fluency task in schizophrenia: a multi-channel near-infrared spectroscopy studyRyu Takizawa
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Schizophr Res 99:250-62. 2008....
Association between catechol-O-methyltrasferase Val108/158Met genotype and prefrontal hemodynamic response in schizophreniaRyu Takizawa
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
PLoS ONE 4:e5495. 2009..Here, we investigated spatiotemporal characteristics of the association between prefrontal hemodynamic activation and the COMT genotype using a noninvasive neuroimaging technique, near-infrared spectroscopy (NIRS)...
Multiple-time replicability of near-infrared spectroscopy recording during prefrontal activation task in healthy menToshiaki Kono
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Neurosci Res 57:504-12. 2007..Further studies using different conditions or assessing sensitivity to longitudinal changes following interventions are necessary...
Decreased prefrontal activation during letter fluency task in adults with pervasive developmental disorders: a near-infrared spectroscopy studyHitoshi Kuwabara
Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Behav Brain Res 172:272-7. 2006..The present results may be also potentially useful for applying NIRS to clinical settings of child psychiatry...
Different hemodynamic response patterns in the prefrontal cortical sub-regions according to the clinical stages of psychosisShinsuke Koike
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
Schizophr Res 132:54-61. 2011..Multichannel near-infrared spectroscopy (NIRS), which can easily and noninvasively measure hemodynamics over the prefrontal cortex, is a candidate instrument for clinical use...
Gender difference in right lateral prefrontal hemodynamic response while viewing fearful faces: a multi-channel near-infrared spectroscopy studyKohei Marumo
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Neurosci Res 63:89-94. 2009..This observation may help to establish NIRS as a clinical tool for monitoring prefrontal function on an individual basis...
Association between severe dorsolateral prefrontal dysfunction during random number generation and earlier onset in schizophreniaShinsuke Koike
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Clin Neurophysiol 122:1533-40. 2011..Age at onset is a major factor for predicting social outcome in schizophrenia. In clinical settings, we need an objective assessment tool for evaluating prefrontal function and social outcome...
Developmental changes of prefrontal activation in humans: a near-infrared spectroscopy study of preschool children and adultsYuki Kawakubo
Department of Child Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
PLoS ONE 6:e25944. 2011..Although the developmental change of the frontopolar PFC was independent of gender from childhood to adolescence, in adulthood a gender difference was shown...
Phonological fluency is uniquely impaired in Japanese-speaking schizophrenia patients: confirmation studyMotomu Suga
Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Psychiatry Clin Neurosci 65:672-5. 2011....
A multimodal approach to investigate biomarkers for psychosis in a clinical setting: the integrative neuroimaging studies in schizophrenia targeting for early intervention and prevention (IN-STEP) projectShinsuke Koike
Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
Schizophr Res 143:116-24. 2013..0%, and 35.3% (at 6, 12, and 24months, respectively). Through this research project, we expect to clarify the pathophysiological features around the onset of psychosis and improve the prognosis of psychosis through clinical application...
