H Takeuchi

Summary

Affiliation: University of Fukui
Country: Japan

Publications

  1. ncbi request reprint Mitotic activity of multinucleated giant cells with glial fibrillary acidic protein immunoreactivity in glioblastomas: an immunohistochemical double labeling study
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23 3 Shimoaizuki, 910 1193, Matsuoka, Fukui, Japan
    J Neurooncol 78:15-8. 2006
  2. ncbi request reprint Cervical extradural meningioma with rapidly progressive myelopathy
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23 3 Shimoaizuki, Matsuoka, Fukui 910 1193, Japan
    J Clin Neurosci 13:397-400. 2006
  3. ncbi request reprint Epithelial differentiation and proliferative potential in spinal ependymomas
    Hiroaki Takeuchi
    Department of Neurosurgery, Fukui Medical University, Yoshida gun, Japan
    J Neurooncol 58:13-9. 2002
  4. ncbi request reprint Angiogenesis in primary central nervous system lymphoma (PCNSL)
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuoka Shimoaizuki, Eiheiji, Fukui 910 1193, Japan
    J Neurooncol 84:141-5. 2007
  5. ncbi request reprint Atypical neuronal-glial tumors of cerebral hemispheres in adults with PNET-like component: clinicopathological features of 5 cases
    H Takeuchi
    Department of Neurosurgery, Fukui Medical University, Matsuoka, Fukui, Japan
    Clin Neuropathol 22:47-56. 2003
  6. ncbi request reprint Frameless stereotactic radiosurgery with mobile CT, mask immobilization and micro-multileaf collimators
    H Takeuchi
    Department of Neurosurgery, Fukui Medical University, Fukui, Japan
    Minim Invasive Neurosurg 46:82-5. 2003
  7. doi request reprint A report of supratentorial leptomeningeal hemangioblastoma and a literature review
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan
    Neuropathology 28:98-102. 2008
  8. ncbi request reprint Prognostic value of vascular endothelial growth factor and its receptors Flt-1 and Flk-1 in astrocytic tumours
    Y Yao
    Department of Neurosurgery, Fukui Medical University, Matsuoka, Japan
    Acta Neurochir (Wien) 143:159-66. 2001
  9. ncbi request reprint Perfusion imaging of meningioma by using continuous arterial spin-labeling: comparison with dynamic susceptibility-weighted contrast-enhanced MR images and histopathologic features
    H Kimura
    Department of Radiology, Faculty of Medical Science, University of Fukui, Fukui, Japan
    AJNR Am J Neuroradiol 27:85-93. 2006
  10. ncbi request reprint Successful removal after radiotherapy and vascular embolization in a huge tentorial epithelioid hemangioendothelioma: a case report
    Toshihiko Kubota
    Department of Neurosurgery, Faculty of Medical Sciences, Fukui University, Matsuoka, Fukui, Japan
    J Neurooncol 68:177-83. 2004

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Mitotic activity of multinucleated giant cells with glial fibrillary acidic protein immunoreactivity in glioblastomas: an immunohistochemical double labeling study
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23 3 Shimoaizuki, 910 1193, Matsuoka, Fukui, Japan
    J Neurooncol 78:15-8. 2006
    ..MNGCs identified in glioblastomas may develop via not only the proliferation of abnormal nuclei in a single tumor cell but also other processes...
  2. ncbi request reprint Cervical extradural meningioma with rapidly progressive myelopathy
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23 3 Shimoaizuki, Matsuoka, Fukui 910 1193, Japan
    J Clin Neurosci 13:397-400. 2006
    ..At surgery, the tumour was entirely extradural. Histological examination revealed a meningioma. The patient recovered without neurological deficit with no recurrence 3 years after surgery...
  3. ncbi request reprint Epithelial differentiation and proliferative potential in spinal ependymomas
    Hiroaki Takeuchi
    Department of Neurosurgery, Fukui Medical University, Yoshida gun, Japan
    J Neurooncol 58:13-9. 2002
    ..Regional differences in ependymomas may influence not only clinical features but also histo-pathological characteristics...
  4. ncbi request reprint Angiogenesis in primary central nervous system lymphoma (PCNSL)
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuoka Shimoaizuki, Eiheiji, Fukui 910 1193, Japan
    J Neurooncol 84:141-5. 2007
    ..Angiogenesis is associated with VEGF expression and an absent BBB in the vessels of PCNSL. The BBB may be preserved in lesions with lymphoma cell infiltration, especially in VEGF- PCNSL. VEGF may have a prognostic effect in PCNSL...
  5. ncbi request reprint Atypical neuronal-glial tumors of cerebral hemispheres in adults with PNET-like component: clinicopathological features of 5 cases
    H Takeuchi
    Department of Neurosurgery, Fukui Medical University, Matsuoka, Fukui, Japan
    Clin Neuropathol 22:47-56. 2003
    ..These tumors were characterized as neuronal and astrocytic differentiated tumors with primitive PNET-like component. However, there was little oligodendrocytic or ependymal differentiation in these tumors...
  6. ncbi request reprint Frameless stereotactic radiosurgery with mobile CT, mask immobilization and micro-multileaf collimators
    H Takeuchi
    Department of Neurosurgery, Fukui Medical University, Fukui, Japan
    Minim Invasive Neurosurg 46:82-5. 2003
    ..5) This system can be used on any part of the body. 6) This system can be installed in any irradiation room without any extension or new construction...
  7. doi request reprint A report of supratentorial leptomeningeal hemangioblastoma and a literature review
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan
    Neuropathology 28:98-102. 2008
    ..Immunohistochemistry for epithelial membrane antigen (EMA) and S100 may be helpful to make differential diagnosis. Electron microscopic investigation is essential to differentiate between meningiomas and other leptomeningeal tumors...
  8. ncbi request reprint Prognostic value of vascular endothelial growth factor and its receptors Flt-1 and Flk-1 in astrocytic tumours
    Y Yao
    Department of Neurosurgery, Fukui Medical University, Matsuoka, Japan
    Acta Neurochir (Wien) 143:159-66. 2001
    ....
  9. ncbi request reprint Perfusion imaging of meningioma by using continuous arterial spin-labeling: comparison with dynamic susceptibility-weighted contrast-enhanced MR images and histopathologic features
    H Kimura
    Department of Radiology, Faculty of Medical Science, University of Fukui, Fukui, Japan
    AJNR Am J Neuroradiol 27:85-93. 2006
    ....
  10. ncbi request reprint Successful removal after radiotherapy and vascular embolization in a huge tentorial epithelioid hemangioendothelioma: a case report
    Toshihiko Kubota
    Department of Neurosurgery, Faculty of Medical Sciences, Fukui University, Matsuoka, Fukui, Japan
    J Neurooncol 68:177-83. 2004
    ..The patient is free from the tumor 9 years after the second operation. Thus, E-HE is a highly vascular-rich tumor to excise, and we stress need for preoperative embolization and/or irradiation to remove huge tumor completely...
  11. ncbi request reprint Atlas hypoplasia associated with non-traumatic retro-odontoid mass
    Kazufumi Sato
    Division of Neurosurgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Japan
    Neurol Med Chir (Tokyo) 46:202-5. 2006
    ..No histological confirmation of the retro-odontoid mass was obtained. Clinical manifestations improved after posterior decompression. Decompressive laminectomy of the atlas with or without fusion can achieve a good outcome in such cases...
  12. ncbi request reprint Immunohistochemical and ultrastructural study of chordoid glioma of the third ventricle: its tanycytic differentiation
    Kazufumi Sato
    Department of Neurosurgery, Fukui Medical University, 23 Shimoaizuki, Yoshida gun, Matsuoka cho, 910 1193 Fukui, Japan
    Acta Neuropathol 106:176-80. 2003
    ..This region includes the lamina terminalis, infundibular recess and median eminence, which corresponds to a tanycyte-rich area. These findings suggest a tanycytic origin of chordoid glioma...
  13. ncbi request reprint Proliferation of vascular smooth muscle cells in glioblastoma multiforme
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Japan
    J Neurosurg 113:218-24. 2010
    ....
  14. ncbi request reprint Astroblastoma: immunohistochemical and ultrastructural study of distinctive epithelial and probable tanycytic differentiation
    Toshihiko Kubota
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Matsuoka cho, Yoshida gun, Fukui, Japan
    Neuropathology 26:72-81. 2006
    ..Numerous microvilli protruded and basal lamina abutted on the tumor cell surface. We report these unique histological features, and stress that astroblastoma should be categorized as a specific type of neuroepithelial tumor...
  15. ncbi request reprint Cell-specific but p53-independent regulation of vascular endothelial growth factor expression by interferons in human glioblastoma cells
    Yongxue Yao
    Department of Neurosurgery, University of Fukui, Matsuoka, Fukui, 910 1193, Japan
    J Neurooncol 76:219-25. 2006
    ..These findings suggest that VEGF might be an indirect target gene of IFNs, and might provide insights into therapeutic applications of IFNs against angiogenesis-dependent tumors...
  16. ncbi request reprint Prognostic significance of microvessel density determined by an anti-CD105/endoglin monoclonal antibody in astrocytic tumors: comparison with an anti-CD31 monoclonal antibody
    Yongxue Yao
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
    Neuropathology 25:201-6. 2005
    ..These findings suggest that anti-CD105 mAb may be a better marker than anti-CD31 mAb in evaluation of angiogenesis and prediction of prognosis in astrocytic tumors...
  17. ncbi request reprint CD98 immunoreactivity in multinucleated giant cells of glioblastomas: an immunohistochemical double labeling study
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
    Neuropathology 28:127-31. 2008
    ..8 +/- 2.7%) was significantly lower than that of CD98- MNGCs (91.1 +/- 24.6%) (P < 0001). These results suggest that multinucleated giant cell formation may be developed by fusion among CD98- producing cells in glioblastomas...
  18. doi request reprint Melanocytoma in the orbital apex
    Kazufumi Sato
    Division of Neurosurgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, 23 Shimoaizuki, Matsuoka, Eiheiji cho, Yoshida gun, 910 1193, Fukui, Japan
    J Neurooncol 92:107-10. 2009
    ..To our knowledge, this is the second published case of intraorbital melanocytoma initially confined to the orbital apex. Melanocytoma should be included in the differential diagnosis of intraorbital tumors in such a location...
  19. ncbi request reprint Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma
    S Shimato
    Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Gene Ther 14:1132-42. 2007
    ..Our data suggest that the CD-NSC strategy can also be applied to target leptomeningeal dissemination of medulloblastomas...
  20. doi request reprint Prognostic significance of the immunohistochemical expression of O6-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas
    Takao Nakagawa
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Yoshida gun, Fukui, Japan
    Neuropathology 29:379-88. 2009
    ....
  21. doi request reprint Expression of vascular endothelial growth factor-A and mRNA stability factor HuR in human astrocytic tumors
    Kazunori Ido
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Yoshida gun, Fukui, Japan
    Neuropathology 28:604-11. 2008
    ..These findings suggest that the expression of VEGF-A and cytoplasmic translocation of HuR relates to the histological grade, and that HuR is involved in the upregulation of VEGF-A expression, in human astrocytic tumors...
  22. doi request reprint Nestin expression in astrocytic tumors delineates tumor infiltration
    Ryuhei Kitai
    Department of Neurosurgery, Faculty of Medical Sciences, Fukui University, Matsuoka, Yoshida gun, Fukui 910 1193, Japan
    Brain Tumor Pathol 27:17-21. 2010
    ..Overlaid images showed that nestin immunostaining delineated tumor invasion into adjacent gray and white matter. Nestin is a useful marker for examining the infiltration of malignant cells into surrounding tissue...
  23. doi request reprint Pathology of intracranial germ cell tumors
    Kazufumi Sato
    Division of Neurosurgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan
    Prog Neurol Surg 23:59-75. 2009
    ..Recently, p14 and c-kit gene alterations have been reported, particularly in some intracranial germinomas; however, their importance remains unclear...
  24. ncbi request reprint Epstein-Barr virus-associated primary central nervous system lymphoma in the Japanese population
    Ryuhei Kitai
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Fukui
    Neurol Med Chir (Tokyo) 50:114-8. 2010
    ..Infrequent association suggests a different pathogenetic mechanism in the evolution of these tumors. Geographical differences in the incidence of EBV-associated primary CNS lymphoma may reflect epidemiological factors...
  25. ncbi request reprint Measurement of the vascularity and vascular leakage of gliomas by double-echo dynamic magnetic resonance imaging: a preliminary study
    Hidemasa Uematsu
    Department of Radiology, Fukui Medical University, Fukui, Japan
    Invest Radiol 37:571-6. 2002
    ..To evaluate the vascularity and vascular leakage of well-enhanced gliomas by double-echo dynamic magnetic resonance (MR) imaging...
  26. doi request reprint Chromosome 1p and 19q deletions in malignant glioneuronal tumors with oligodendroglioma-like component
    Hiroaki Takeuchi
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuoka Shimoaizuki, Eiheiji, Fukui, 910 1193, Japan
    J Neurooncol 91:33-8. 2009
    ..It is inappropriate to make a diagnosis of oligodendroglioma based only on morphological resemblance to oligodendroglia...
  27. doi request reprint Tissue characterization of glioma by proton magnetic resonance spectroscopy and perfusion-weighted magnetic resonance imaging: glioma grading and histological correlation
    Mariko Toyooka
    Department of Radiology, University of Fukui, Fukui 910 1193, Japan
    Clin Imaging 32:251-8. 2008
    ..Our intent was to clarify the usefulness of proton magnetic resonance spectroscopy (MRS) and perfusion-weighted magnetic resonance imaging (PW-MRI) in the grading of glioma...
  28. ncbi request reprint Expression of vascular endothelial growth factor-A and mRNA stability factor HuR in human meningiomas
    Takahiro Sakuma
    Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Yoshida gun, Fukui 910 1193, Japan
    J Neurooncol 88:143-55. 2008
    ..These findings suggest that the expression of VEGF-A relates to the development of PTBE with meningiomas and the histological grade, and that HuR is involved in the upregulation of VEGF-A expression in human meningiomas...
  29. ncbi request reprint Grading of brain glioma with 1-11C-acetate PET: comparison with 18F-FDG PET
    Tatsuro Tsuchida
    Department of Radiology, Faculty of Medical Sciences, University of Fukui, Fukui 910 1193, Japan
    Nucl Med Biol 35:171-6. 2008
    ..The objective of this study is to reevaluate the clinical significance of 1-11C-acetate (ACE) positron emission tomography (PET) in patients with brain glioma, in comparison with 18F-fluorodeoxyglucose (FDG) PET...
  30. ncbi request reprint Radiological findings for arterial dissection of the anterior cerebral artery
    Toshiaki Kodera
    Department of Neurosurgery, Fukui General Hospital, Fukui 910 8561, Japan
    J Clin Neurosci 14:77-80. 2007
    ..We presume that the results were based on the velocity of the blood flow in the pseudolumen of the dissected artery, and we believe that CT angiography is a useful and less invasive diagnostic tool for intracranial arterial dissection...
  31. ncbi request reprint Dural sinus thrombosis with marked enlargement of the venous sinus--case report
    Toshiaki Kodera
    Department of Neurosurgery, Sugita Genpaku Memorial Obama Municipal Hospital, Obama, Fukui, Japan
    Neurol Med Chir (Tokyo) 50:59-61. 2010
    ..We believe this condition developed from use of oral contraceptives. Systemic anticoagulant therapy was effective without hemorrhagic complication...
  32. ncbi request reprint Ultrastructure of capillary endothelium in pilocytic astrocytomas
    Hiroaki Takeuchi
    Department of Neurosurgery, Obama Community Hospital, Obama, Fukui 917 8567, Japan
    Brain Tumor Pathol 21:23-6. 2004
    ..Fenestration of the vessels and vascular abnormalities with degeneration are suggested to develop both contrast enhancement on neuroimaging and cystic formation in pilocytic astrocytomas...
  33. ncbi request reprint Thymic mucosa-associated lymphoid tissue lymphoma associated with bilateral orbital pseudotumor
    Ryuhei Kitai
    Department of Neurosurgery, Faculties of Medical Sciences, Fukui University, Yoshida gun, Fukui, Japan
    Gen Thorac Cardiovasc Surg 57:566-9. 2009
    ..Eleven years later, a mediastinal tumor was incidentally discovered. A thymectomy was performed, and histological examination revealed that the mass was a MALT lymphoma. There was no recurrence with no further treatment...
  34. ncbi request reprint [Atrial wall hematoma after mitral valvuloplasty and maze procedure: a case report]
    Ayuko Shimozato
    Department of Cardiovascular Medicine, Japanese Red Cross Medical Center, Hiroo 4 1 22, Shibuya ku, Tokyo 150 8935
    J Cardiol 48:353-8. 2006
    ..This rare case of atrial wall hematoma, especially after the maze procedure, required differential diagnosis from intraatrial thrombus and atrial wall dissection...
  35. pmc Inhibition of human immunodeficiency virus type 1 activity in vitro by a new self-stabilized oligonucleotide with guanosine-thymidine quadruplex motifs
    Jun ichiro Suzuki
    Department of Industrial Chemistry, Chiba Institute of Technology, 2 17 1 Tsudanuma, Narashino, Chiba 275 0016, Japan
    J Virol 76:3015-22. 2002
    ..We also found that dG3T4G3-s specifically inhibits the entry of T-cell line-tropic HIV-1 into cells. This compound is a viable candidate for evaluation as a therapeutic agent against HIV-1 in humans...
  36. ncbi request reprint Cell elongation and cell death of helicobacter pylori is modulated by the disruption of cdrA (cell division-related gene A)
    Hiroaki Takeuchi
    Department of Clinical Laboratory Medicine, Kochi University School of Medicine, Nankoku, Kochi, Japan
    Microbiol Immunol 50:487-97. 2006
    ....
  37. ncbi request reprint Interferons upregulate thymidine phosphorylase expression via JAK-STAT-dependent transcriptional activation and mRNA stabilization in human glioblastoma cells
    Yongxue Yao
    Department of Neurosurgery Department of Microbiology and Immunology, Indiana University School of Medicine and Walther Oncology Center, Indianapolis, IN 46202, USA
    J Neurooncol 72:217-23. 2005
    ..Combined treatment with IFN and 5-fluorouracil may be a useful therapeutic strategy for malignant gliomas...
  38. ncbi request reprint Pretreatments with a novel pure potassium channel blocker, Nifekalant, were effective in the electrical atrial defibrillation: a report of two cases
    Gaku Sekita
    Department of Cardiovascular Medicine, Japanese Red Cross Medical Center, Tokyo
    Cardiovasc Drugs Ther 16:551-2. 2002
  39. ncbi request reprint Assessment of autonomic dysfunction of multiple system atrophy with laryngeal abductor paralysis as an early manifestation
    Kazushi Deguchi
    Department of Gastroenterology and Neurology, Kagawa University School of Medicine, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa 761 0793, Japan
    Clin Neurol Neurosurg 109:892-5. 2007
    ..Diagnosis of atypical MSA with LAP in the early stages might be accelerated by a detailed investigation focused on urinary symptoms and neuroendocrine approaches...
  40. ncbi request reprint [Clinical results of LINAC-based stereotactic radiosurgery for pituitary adenoma]
    Julia Muramatsu
    Department of Radiology, Fukui Medical University School of Medicine
    Nihon Igaku Hoshasen Gakkai Zasshi 63:225-30. 2003
    ..We retrospectively evaluated our clinical results of stereotactic radiosurgery (SRS) for pituitary adenoma...
  41. ncbi request reprint The study of cytopathological aspects induced by human cytomegalovirus infection
    Takako Takeuchi
    Department of Pathology, Shimonosekishi ishikai Hospital, Shimonoseki, Japan
    Diagn Cytopathol 31:289-93. 2004
    ..In FISH, the positive signal highlighted viral particles that became predominant and localized in nuclei. These cytological aspects are dependent on viral replication and contribute to the cytological detection of HCMV infection...
  42. ncbi request reprint [Chronic acquired hepatocerebral degeneration]
    Hiroaki Takeuchi
    School of Nursing, Kagawa Medical University
    Nihon Rinsho 62:419-23. 2004