Research Topics
| T TakayamaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Publications
Segmental liver resections, present and future-caudate lobe resection for liver tumorsT Takayama
Second Department of Surgery, Faculty of Medicine, University of Tokyo, Japan
Hepatogastroenterology 45:20-3. 1998..Resection of the caudate lobe of the liver is difficult to perform because of a deep location and an adjacency to the major vessels...
Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trialT Takayama
Department of Surgery, National Cancer Centre Research Institute, University of Tokyo, Japan
Lancet 356:802-7. 2000..Postsurgical recurrence of hepatocellular carcinoma (HCC) is frequent and fatal. Adoptive immunotherapy is active against HCC. We assessed whether postoperative immunotherapy could lower the frequency of recurrence...
Decreased p27(Kip1) expression and cyclin D1 overexpression, alone and in combination, influence recurrence and survival of patients with resectable extrahepatic bile duct carcinomaA M Hui
Hepato Biliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
Hepatology 30:1167-73. 1999..In conclusion, decreased p27(Kip1) expression and cyclin D1 overexpression, alone and in combination, predict poor prognosis in patients with resectable extrahepatic bile duct carcinoma...
Surgical treatment of intrahepatic cholangiocarcinoma: four patients surviving more than five yearsJ Yamamoto
Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
Surgery 111:617-22. 1992..CONCLUSIONS. An anatomic and extensive liver resection should be performed for mass-forming ICC, whereas a hepatectomy with excision of the extrahepatic bile duct and hilar lymph nodal dissection is recommended for infiltrating ICC...
Liver resection without total vascular exclusion: hazardous or beneficial? An analysis of our experienceG Torzilli
Hepato Biliary Pancreatic Surgery Division, Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Ann Surg 233:167-75. 2001..To evaluate retrospectively the safety and radicality of liver resection performed without total vascular exclusion (TVE)...
p27(Kip1) expression in normal epithelia, precancerous lesions, and carcinomas of the gallbladder: association with cancer progression and prognosisA M Hui
Hepato Biliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Hepatology 31:1068-72. 2000..034; risk ratio, 3.9; 95% confidence interval, 1.1-13.7). In conclusion, decreased p27(Kip1) expression significantly correlates with tumor progression and predicts poor prognosis in gallbladder carcinomas...
Liver transplantation using a right lateral sector graft from a living donor to her granddaughterY Sugawara
Liver Transplant Team, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
Hepatogastroenterology 48:261-3. 2001..Right lateral sector graft obtained by this innovative procedure may be useful for overcoming borderline graft-recipient size and shape differences...
Kinetics of urinary trypsin inhibitor in patients undergoing partial hepatectomyT Noie
Dept. of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Scand J Gastroenterol 36:410-6. 2001..CONCLUSIONS: The postoperative urine UTI level may reflect preoperative liver function and the extent of liver resection after partial hepatectomy...
Tumor angiogenesis in gallbladder carcinomaY Sugawara
Second Department of Surgery, Faculty of Medicine, University of Tokyo, Japan
Hepatogastroenterology 46:1682-6. 1999..Although the microvessel count in some kinds of solid tumor was shown to correlate with clinical outcome, little is known about its significance in gallbladder carcinoma...
Over-expression and lack of retinoblastoma protein are associated with tumor progression and metastasis in hepatocellular carcinomaA M Hui
Hepato Biliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Int J Cancer 84:604-8. 1999..Our observations suggest that elevated and absent Rb protein are closely associated with tumor progression and developing metastatic disease rather than tumor initiation in cases of HCC. Int. J. Cancer (Pred. Oncol.) 84:604-608, 1999...
Primary hepatic carcinoid tumors confirmed with long-term follow-up after resectionK Sano
Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
Hepatogastroenterology 46:2547-50. 1999..Surgery might offer a possible chance of cure for primary hepatic carcinoid tumor, and transcatheter arterial embolization might be a good treatment option when an unresectable disease is confined to the liver...
Prognostic importance of tumour-infiltrating memory T cells in oesophageal squamous cell carcinomaK Enomoto
Department of Surgery, Nara Medical University, Nara, Japan
Clin Exp Immunol 168:186-91. 2012..Our study may provide a rationale for developing a novel immunotherapy in intentional induction of memory T cells for the treatment of oesophageal cancer...
Hepatic resection for hepatocellular carcinoma -- Japanese experienceM Makuuchi
Department of Surgery, Faculty of Medicine, Tokyo, Japan
Hepatogastroenterology 45:1267-74. 1998..Therefore, in patients with small HCCs and good liver function, the first choice treatment should not be ethanol injection, but surgical resection...
US guided biliary drainage during hepatopancreatico-jejunostomy for diffuse bile duct carcinomaG Torzilli
Department of Surgery, University of Tokyo, Faculty of Medicine, Japan
Hepatogastroenterology 46:863-6. 1999..If a nasobiliary catheter is positioned pre-operatively, biliary drainage can be maintained during hepatopancreato-duodenectomy by introducing a transhepatic drain under sonographic guidance. This original technique is described herein...
Lactate is correlated with the indocyanine green elimination rate in liver resection for cirrhotic patientsR Orii
Department of Anesthesiology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
Anesth Analg 92:1064-70. 2001..The blood lactate profile might be a reliable indicator of liver metabolic capacity during surgery...
Telomerase activity as a predictive marker for recurrence of hepatocellular carcinoma after hepatectomyT Kobayashi
Hepato Biliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, 113 0033, Tokyo, Japan
Am J Surg 181:284-8. 2001..Telomerase activity levels in hepatocellular carcinoma (HCC) may serve as a predictive marker for recurrence after surgery...
Reversible hepatofugal portal flow after liver transplantation using a small-for-size graft from a living donorY Kita
Department of Surgery, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Transpl Int 14:217-22. 2001..Liver transplant clinicians should be aware that hepatofugal flow can occur with small-for-size liver grafts, despite sufficient portal venous flow immediately after transplantation...
Hepatic phenylalanine metabolism measured by the [13C]phenylalanine breath testT Kobayashi
Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Eur J Clin Invest 31:356-61. 2001..This study evaluates whether phenylalanine oxidation capacity measured by a breath test could reflect liver functional reserve...
Small-for-size grafts in living-related liver transplantationY Sugawara
Liver Transplant Team, University of Tokyo, Japan
J Am Coll Surg 192:510-3. 2001..0001 for both). CONCLUSIONS: Our surgical results may suggest that a graft weight ratio of 40% or less provides a lower chance of survival after living-related liver transplantation...
Risk factors for acute rejection in pediatric living related liver transplantation: the impact of HLA matchingY Sugawara
Liver Transplantation Team, University of Tokyo, Tokyo, Japan
Liver Transpl 7:769-73. 2001..004) had a significantly lower chance of rejection within 6 weeks after LRLT. Our results show that in LRLT, a graft from an HLA-A zero-mismatched donor may be advantageous because it provides a lower chance of early acute rejection...
Selection criteria for hepatectomy in patients with hepatocellular carcinoma and portal vein tumor thrombusM Minagawa
Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Ann Surg 233:379-84. 2001....
Lactate levels in cirrhotic patients undergoing liver resectionM Kato
Hepatobiliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
Hepatogastroenterology 48:1106-9. 2001..06). CONCLUSIONS: The blood lactate profile might be a reliable indicator of liver function during the perioperative period in cirrhotic patients who undergo liver resection with Pringle's maneuver...
Cyclin D1 overexpression is a critical event in gallbladder carcinogenesis and independently predicts decreased survival for patients with gallbladder carcinomaA M Hui
Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Clin Cancer Res 6:4272-7. 2000..In conclusion, cyclin D1 overexpression is an early event in gallbladder carcinogenesis and independently predicts decreased survival for patients with GBC...
Reduced p21(WAF1/CIP1) protein expression is predominantly related to altered p53 in hepatocellular carcinomasY Z Shi
Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Br J Cancer 83:50-5. 2000....
Loss of p16(INK4) protein, alone and together with loss of retinoblastoma protein, correlate with hepatocellular carcinoma progressionA M Hui
Hepato Biliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
Cancer Lett 154:93-9. 2000..In conclusion, p16(INK4) protein absence, alone and together with loss of retinoblastoma protein, contributes to hepatocellular carcinoma progression...
Liver transplantation from situs inversus to situs inversusY Sugawara
Liver Transplant Team, University of Tokyo, Tokyo, Japan
Liver Transpl 7:829-30. 2001..This case was particularly rare because the donor also had situs inversus, which made the present procedure more feasible...
Appraisal of two-staged pancreatoduodenectomy: its technical aspects and outcomeK Kubota
Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Hepatogastroenterology 47:269-74. 2000..Recently, two-staged pancreatoduodenectomy including exteriorization of the pancreatic juice and second-look pancreaticojejunostomy was performed in high-risk patients...
Living-related liver transplantation for primary biliary cirrhosisY Sugawara
Department of Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
Transplantation 72:1087-91. 2001..To achieve the best possible outcome, further therapeutic tactics are necessary for patients with conventional or updated Mayo risk scores of more than 10 or 12, respectively...
Selective versus total drainage for biliary obstruction in the hepatic hilus: an experimental studyT Noie
Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Surgery 130:74-81. 2001..CONCLUSIONS: SBD is superior to TBD with regard to the functional reserve of the future remnant liver...
A new staging system for mass-forming intrahepatic cholangiocarcinoma: analysis of preoperative and postoperative variablesT Okabayashi
Department of Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
Cancer 92:2374-83. 2001..CONCLUSIONS: The current results support the use of a new staging system for patients with ICC that is simple and predicts well the differences in survival after patients undergo hepatic resection...
Outcomes after open surgery and endovascular aneurysm repair for abdominal aortic aneurysm in patients with massive neck atheromaK Hoshina
Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Eur J Vasc Endovasc Surg 43:257-61. 2012....
Inflammatory pseudotumors of the liver: prevalence and clinical impact in surgical patientsG Torzilli
Hepato Biliary Pancreatic Surgery Division, Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
Hepatogastroenterology 48:1118-23. 2001..To estimate their prevalence and clinical impact in surgical series we evaluate retrospectively our experience...
Randomized comparison of ultrasonic vs clamp transection of the liverT Takayama
Division of Hepato-Biliary-Pancreatic and Transplantation Surgery, Department of Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
Arch Surg 136:922-8. 2001..92; P =.01). CONCLUSIONS: Ultrasonic dissection offers no reduction in blood loss compared with clamp crushing for transection of the liver. Clamp crushing results in a higher quality of hepatectomy and is therefore the option of choice...
Restoration of portal vein flow by splenorenal shunt ligation and splenectomy after living-related liver transplantationM Cescon
Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
Hepatogastroenterology 48:1453-4. 2001..Although the role of splenectomy was controversial, splenectomy provided an increased portal vein flow in the present case. The uneventful postoperative course validated our decision...
Current status of the medical expenses for the treatment of arteriosclerosis obliterans in JapanT Isaji
Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Japan
Int Angiol 29:61-8. 2010..We aimed to determine the current status of the medical expenses for the treatment of arteriosclerosis obliterans (ASO) and evaluate the cost effectiveness of the medical practices employed in ASO treatment in Japan...
Ventral dissection of replaced right hepatic artery during pancreatoduodenectomyT Noie
Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Hepatogastroenterology 48:999-1000. 2001..The periaortic lymph nodes can also be resected en bloc with the main lesion...
Prophylactic pancreatic stent placement and post-ERCP pancreatitis: a systematic review and meta-analysisT Mazaki
Division of Digestive Surgery, Department of Surgery, Nihon University School of Medicine, 2 11 1 Hikarigaoka, Nerima ku, Tokyo, Japan
Endoscopy 42:842-53. 2010..We aimed to provide an up-to-date meta-analysis regarding pancreatic stent placement for prevention of PEP and review the immediate adverse events associated with pancreatic stent placement...
Outcomes of renal transplantation after end-stage renal disease due to diabetic nephropathy: a single-center experienceK Tokodai
Department of Surgery, Sendai Shakaihoken Hospital, Miyagi, Japan
Transplant Proc 44:77-9. 2012..However, data on renal transplantation outcomes in diabetic nephropathy among Japanese remain inadequate. This retrospective study was conducted to summarize our renal transplantation experience in diabetic ESRD patients...
Quadruple cancer including Bowen's disease after arsenic injections 40 years earlier: report of a caseK Murata
Department of Surgery, Kinki Central Hospital of the Mutual Aid Association of Public School Teachers, Itami, Japan
Surg Today 24:1115-8. 1994..A discussion of multiple malignant neoplasms and the possible relationship between arsenic and cancer is presented following this case report...
Reduced p21(WAF1/CIP1) expression is an early event in gallbladder carcinogenesis and is of prognostic significance for patients with carcinomas of the gallbladderX Li
Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Hum Pathol 32:771-7. 2001....
An obstructed venous aneurysm presenting as an abdominal mass: report of a caseY Kishi
Department of Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tokyo, Japan
Surg Today 31:336-9. 2001..This report serves to demonstrate that a venous aneurysm should be considered in the differential diagnosis of an asymptomatic abdominal mass...
Increase in the concentration of carbon 18 monounsaturated fatty acids in the liver with hepatitis C: analysis in transgenic mice and humansK Moriya
Department of Internal Medicine, University of Tokyo, Tokyo, Japan
Biochem Biophys Res Commun 281:1207-12. 2001..These results suggest that HCV may affect a specific pathway in the lipid metabolism and cause steatosis in the liver...
A comparison of surgery and radiation therapy for cT1 esophageal squamous cell carcinomaS Matsumoto
Department of Surgery, Nara Medical University School of Medicine, Nara, Japan
Dis Esophagus 24:411-7. 2011..8%; P= 0.0219). In conclusion, surgery may become a standard treatment for cT1 esophageal cancer that can offer longer relapse-free survival, particularly for patients with tumors that invade the submucosa...
