Affiliation: University of Tokyo
Kimura N, Takahashi Y, Shigematsu H, Imai K, Ikeda H, Ootani H, et al
. Developmental outcome after surgery in focal cortical dysplasia patients with early-onset epilepsy. Epilepsy Res. 2014;108:1845-52 pubmed publisher
..In patients of Engel's class I with lower presurgical DQ-IQ, catch-up increase in mental age was observed after two years following surgery. ..
Takahashi Y, Mori H, Mishina M, Watanabe M, Fujiwara T, Shimomura J, et al
. Autoantibodies to NMDA receptor in patients with chronic forms of epilepsia partialis continua. Neurology. 2003;61:891-6 pubmed
..Patients with Rasmussen's encephalitis may have autoantibodies against several neural molecules, and these autoantibodies may be produced in the CNS after cytotoxic T cell-mediated neuronal damage. ..
Yoshimura M, Zhang S, Ueda Y, Matsuda K, Imai K, Takahashi Y, et al
. An analysis of epileptic negative myoclonus by magnetoencephalography. Epilepsy Res. 2015;110:139-45 pubmed publisher
..ENM was produced by an inhibitory action on the primary sensorimotor cortex corresponding to the body segment in which ENM occurs. ..
Takahashi Y, Mori H, Mishina M, Watanabe M, Kondo N, Shimomura J, et al
. Autoantibodies and cell-mediated autoimmunity to NMDA-type GluRepsilon2 in patients with Rasmussen's encephalitis and chronic progressive epilepsia partialis continua. Epilepsia. 2005;46 Suppl 5:152-8 pubmed
..We speculate that cellular autoimmunity and the subsequent humoral autoimmunity against GluRepsilon2 may contribute to the pathophysiological processes in Rasmussen's encephalitis. ..
Takahashi Y, Matsudaira T, Nakano H, Nasu H, Ikeda H, Nakaoka K, et al
. Immunological studies of cerebrospinal fluid from patients with CNS symptoms after human papillomavirus vaccination. J Neuroimmunol. 2016;298:71-8 pubmed publisher
..Antibodies to GluN2B-NT2, GluN2B-CT and GluN1-NT increased significantly. These results suggest biological, mainly immunological, changes in the CSF of patients after HPV vaccination. ..
Jogamoto T, Yamamoto Y, Fukuda M, Suzuki Y, Imai K, Takahashi Y, et al
. Add-on stiripentol elevates serum valproate levels in patients with or without concomitant topiramate therapy. Epilepsy Res. 2017;130:7-12 pubmed publisher
..Our findings suggest that serum VPA concentrations should be carefully monitored during STP adjunctive therapy, particularly in patients receiving concomitant TPM therapy. ..
Takahashi Y, Mine J, Kubota Y, Yamazaki E, Fujiwara T. A substantial number of Rasmussen syndrome patients have increased IgG, CD4+ T cells, TNFalpha, and Granzyme B in CSF. Epilepsia. 2009;50:1419-31 pubmed publisher
..A crucial cytotoxic process occurs in the early stage, and declines in the progressed stage. ..