Research Topics
| Yasuo SuzukiSummaryAffiliation: University of Shizuoka Country: Japan Publications
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Detail Information
Publications
Chemoenzymatic synthesis and application of a sialoglycopolymer with a chitosan backbone as a potent inhibitor of human influenza virus hemagglutinationYutaka Makimura
Division of Life Science, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Japan
Carbohydr Res 341:1803-8. 2006..These results indicate that a sialoglycopolymer having a multivalent sialo-oligosaccharide could potentially be used for the prevention of influenza virus infection...
Sialobiology of influenza: molecular mechanism of host range variation of influenza virusesYasuo Suzuki
Department of Biochemistry, University of Shizuoka School of Pharmaceutical Sciences, Shizuoka, Japan
Biol Pharm Bull 28:399-408. 2005....
[Virus and glycan--an exhortation of glycovirology]Yasuo Suzuki
University of Shizuoka, School of Pharmaceutical Sciences, 52-1 Yada, Shizuoka-shi 422-8526
Uirusu 53:127-31. 2003
Sialidase activity of influenza A virus in an endocytic pathway enhances viral replicationTakashi Suzuki
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences and COE Program in the 21st Century, Shizuoka 422 8526, Japan
J Virol 79:11705-15. 2005..These results indicate that sialidase activity in late endosome/lysosome traffic enhances influenza A virus replication...
2-Deoxy-2,3-didehydro-N-acetylneuraminic acid analogues structurally modified at the C-4 position: synthesis and biological evaluation as inhibitors of human parainfluenza virus type 1Kiyoshi Ikeda
Department of Organic Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Suruga ku, Shizuoka 422 8526, Japan
Bioorg Med Chem 14:7893-7. 2006..Among compounds 6a-e, the 4-O-ethyl-Neu5Ac2en derivative 6b showed the most potent inhibitory activity (IC50 6.3 microM) against hPIV-1 sialidase...
Human trachea primary epithelial cells express both sialyl(alpha2-3)Gal receptor for human parainfluenza virus type 1 and avian influenza viruses, and sialyl(alpha2-6)Gal receptor for human influenza virusesToshihiro Kogure
Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan
Glycoconj J 23:101-6. 2006..Thus, cultured NHBE cells showed both alpha2-3-linked Sias recognized by hPIV-1 and avian influenza virus receptors, and alpha2-6-linked Sias recognized by human influenza virus receptors...
Clarithromycin inhibits progeny virus production from human influenza virus-infected host cellsDaisei Miyamoto
Department of Biochemistry, University of Shizuoka School of Pharmaceutical Science, Shizuoka, Japan
Biol Pharm Bull 31:217-22. 2008..These findings indicate that CAM acts on a middle to late stage of the viral replication cycle resulting in inhibition of progeny virus production from the infected cells...
[Role of influenza virus sialidase]Tadanobu Takahashi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, COE Program in the 21st Century, CREST, 52-1 Yada Shizuoka 422-8526, Japan
Seikagaku 78:409-13. 2006
Edible bird's nest extract inhibits influenza virus infectionChao-Tan Guo
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences and COE Program in the 21st Century, Suruga-ku, Shizuoka 422-8526, Japan
Antiviral Res 70:140-6. 2006..Fluorometric HPLC indicated that the major molecular species of sialic acid in EBN is N-acetylneuraminic acid. The results suggest that EBN is a safe and valid natural source for the prevention of influenza viruses...
The low-pH stability discovered in neuraminidase of 1918 pandemic influenza A virus enhances virus replicationTadanobu Takahashi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences and Global COE Program for Innovation in Human Health Sciences, Shizuoka, Japan
PLoS ONE 5:e15556. 2010..Our results suggest that the avian-like low-pH stability of sialidase activity in the 1918 pandemic virus NA contributes to the viral replication efficiency...
Evolutional analysis of human influenza A virus N2 neuraminidase genes based on the transition of the low-pH stability of sialidase activityTakashi Suzuki
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, CREST, JST, and COE Program in the 21st Century, Shizuoka 422 8526, Japan
FEBS Lett 557:228-32. 2004..These findings suggest that the prototype of the H3N2 epidemic influenza strains isolated after 1968 probably acquired the NA gene from the H2N2 low-pH-unstable sialidase strain by second genetic reassortment in humans...
Sulfatide is required for efficient replication of influenza A virusTadanobu Takahashi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka 422 8526, Japan
J Virol 82:5940-50. 2008..Our findings provide new insights into IAV replication and suggest new therapeutic strategies...
Chemoenzymatic synthesis, characterization, and application of glycopolymers carrying lactosamine repeats as entry inhibitors against influenza virus infectionKazuya I P J Hidari
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka, Japan
Glycobiology 18:779-88. 2008..The core carbohydrate portion as well as sialyl linkages on the receptor glycoconjugate may affect host cell recognition of human and swine viruses...
An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza virusesChao-Tan Guo
Department of Biochemistry, University of Shizuoka School of Pharmaceutical Sciences, 52-1 Yada, Shizuoka-shi 422-8526, Japan
Glycobiology 12:183-90. 2002..The study suggested that the compound is a new class of bifunctional drug candidates for the future chemotherapy of influenza...
Antiviral activity of chondroitin sulphate E targeting dengue virus envelope proteinDaisuke Kato
Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, and Global COE Program for Innovation in Human Health Sciences, 52 1 Yada, Suruga ku, Shizuoka shi, Shizuoka 422 8526, Japan
Antiviral Res 88:236-43. 2010..In conclusion, CSE showed antiviral activity as an entry inhibitor targeting E protein of dengue virus...
Binding kinetics of influenza viruses to sialic acid-containing carbohydratesKazuya I P J Hidari
Department of Biochemistry, School of Pharmaceutical Sciences, Core Research for Evolutional Science and Technology CREST, Japan Science and Technology Corporation, University of Shizuoka, Shizuoka shi, Shizuoka, Japan
Glycoconj J 24:583-90. 2007..Our findings demonstrated the remarkable distinction in the binding kinetics of sialic acid-containing carbohydrates between avian and human influenza viruses on the lipid bilayer...
Identification of amino acid residues of influenza A virus H3 HA contributing to the recognition of molecular species of sialic acidTadanobu Takahashi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Shizuoka 422 8526, Japan
FEBS Lett 583:3171-4. 2009..We evaluated the binding ability with four types of synthetic sialylglycolipids. The results indicate that the amino acid substitutions Thr155 to Tyr and Glu158 to Gly in H3 HA facilitate virus binding to N-glycolylneuraminic acid...
Purification and characterization of a soluble recombinant human ST6Gal I functionally expressed in Escherichia coliKazuya I P J Hidari
Department of Biochemistry, School of Pharmaceutical Sciences, Core Research for Evolutional Science and Technology CREST, Japan Science and Technology Corporation, University of Shizuoka
Glycoconj J 22:1-11. 2005..In conclusion, soluble recombinant ST6Gal I obtained using our bacterial expression system is a valuable tool to investigate the molecular mechanisms of biological and pathological interactions mediated via carbohydrates...
Suppression of the biosynthesis of cellular sphingolipids results in the inhibition of the maturation of influenza virus particles in MDCK cellsKazuya I P J Hidari
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research for Evolutional Science and Technology CREST, Japan Science and Technology Corporation, Japan
Biol Pharm Bull 29:1575-9. 2006..Our findings strongly suggest that cellular sphingolipids play important roles in the events after viral adsorption to the host cells...
Restricted expression of shiga toxin binding sites on mucosal epithelium of mouse distal colonYasuyuki Imai
Department of Microbiology, University of Shizuoka School of Pharmaceutical Sciences, Japan
Infect Immun 71:985-90. 2003..The results indicate that Stx1B is stricter in the recognition of carbohydrate determinants than GS-I-B4 when examined with biological ligands...
A molecular mechanism for the low-pH stability of sialidase activity of influenza A virus N2 neuraminidasesTadanobu Takahashi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, CREST, JST, and COE Program in the 21st Century, 422-8526, Shizuoka, Japan
FEBS Lett 543:71-5. 2003....
[Receptor binding specificity of influenza virus and its budding from the host cells]Yasuo Suzuki
Tanpakushitsu Kakusan Koso 48:1141-6. 2003
Sulfatide negatively regulates the fusion process of human parainfluenza virus type 3Tadanobu Takahashi
Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka and Global COE Program, Shizuoka 422 8526, Japan
J Biochem 152:373-80. 2012..The results suggest that sulfatide negatively regulates the fusion process of hPIV3, possibly through interaction with HN or F glycoprotein on the cell surface...
2beta,3beta-Difluorosialic acid derivatives structurally modified at the C-4 position: synthesis and biological evaluation as inhibitors of human parainfluenza virus type 1Kiyoshi Ikeda
Department of Organic Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, 52 1 Yada, Shizuoka 422 8526, Japan
Carbohydr Res 339:1367-72. 2004..OEt(2). Among compounds 3a-d, the 4-O-thiocarbamoylmethyl derivative 3c showed the most potent inhibitory activity against sialidase of human parainfluenza virus type 1. [structure: see text]...
Identification and characterization of carbohydrate molecules in mammalian cells recognized by dengue virus type 2Chie Aoki
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research for Evolutional Science and Technology (CREST, Japan Science and Technology Corporation, and COE Program in the 21st Century
J Biochem 139:607-14. 2006..These findings strongly suggested that multivalent nLc4 oligosaccharide could act as a competitive inhibitor against the binding of DEN2 to the host cells...
In vitro and in vivo inhibitory effects of disodium cromoglycate on influenza virus infectionKazuya I P J Hidari
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Yada, Shizuoka, Japan
Biol Pharm Bull 27:825-30. 2004..Our results indicate that treatment of patients including children with DSCG may take advantages for prevention from influenza virus infection...
[Sugar recognition process in viral infection]Yasuo Suzuki
Department of Biochemistry, University of Shizuoka School of Pharmaceutical Sciences, 52-1 Yada, Shizuoka 422-8526, Japan
Seikagaku 76:227-33. 2004
Virus infection and lipid raftsTakashi Suzuki
COE Program in the 21st Century, Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Japan
Biol Pharm Bull 29:1538-41. 2006..In this review, we describe the involvement of membrane lipid rafts in the virus replication cycle with our current findings for understanding the role of membrane lipid rafts in virus infection...
The highly pathogenic avian influenza H5N1 - initial molecular signals for the next influenza pandemicYasuo Suzuki
Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Aichi, Japan Global COE Program for Innovation in Human Health Sciences, University of Shizuoka School of Pharmaceutical Sciences, Shizuoka, Japan
Chang Gung Med J 32:258-63. 2009..This paper describes recent advances in the mechanism of transmission of highly pathogenic avian influenza to humans and measures for control of a new pandemic...
Inhibition of influenza A virus sialidase activity by sulfatideTakashi Suzuki
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, 422 8526 Shizuoka, Japan
FEBS Lett 553:355-9. 2003..The kinetic parameters of the effect of sulfatide on the sialidase activities of human influenza A viruses using fluorometric assay indicated that sulfatide was a powerful and non-competitive type inhibitor in low-pH conditions...
Thiosialoside clusters using carbosilane dendrimer core scaffolds as a new class of influenza neuraminidase inhibitorsJun Ichi Sakamoto
Division of Materials Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338 8570, Japan
Bioorg Med Chem Lett 17:717-21. 2007..The results of a preliminary study on biological responses against influenza virus sialidases using thiosialoside clusters showed that some of the glycodendrimers have inhibitory potencies against the sialidases...
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptorsShinya Yamada
Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan
Nature 444:378-82. 2006..The amino acid changes that we identify might serve as molecular markers for assessing the pandemic potential of H5N1 field isolates...
Synthesis and evaluation of 4-O-alkylated 2-deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives as inhibitors of human parainfluenza virus type-3 sialidase activityDavid J Tindal
Institute for Glycomics, Griffith University Gold Coast Campus, PMB 50 Gold Coast Mail Centre, Queensland 9726, Australia
Bioorg Med Chem Lett 17:1655-8. 2007..This is comparable or improved activity compared to the parent 4-hydroxy compound...
Influenza viral hemagglutinin complicated shape is advantageous to its binding affinity for sialosaccharide receptorToshihiko Sawada
Department of Applied Bioorganic Chemistry, The United Graduate School of Agricultural Science, Gifu University, 1 1 Yanagido, Gifu 501 1193, Japan
Biochem Biophys Res Commun 355:6-9. 2007..3kcal/mol higher than that of the smallest domain-receptor complex. These data provide the consideration of the backyard bulkiness beyond the binding site of protein to the protein-ligand stability...
The quail and chicken intestine have sialyl-galactose sugar chains responsible for the binding of influenza A viruses to human type receptorsChao Tan Guo
Institute of Bioengineering, Zhejiang Academy of Medical Sciences, 182 Tianmushan Road, Hangzhou 310016, China
Glycobiology 17:713-24. 2007....
The expression of sialylated high-antennary N-glycans in edible bird's nestHirokazu Yagi
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan
Carbohydr Res 343:1373-7. 2008..We suggest that the sialylated high-antennary N-glycans of EBN contribute to the inhibition of influenza viral infection...
Novel linear polymers bearing thiosialosides as pendant-type epitopes for influenza neuraminidase inhibitorsKoji Matsuoka
Area for Molecular Function, Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338 8570, Japan
Bioorg Med Chem Lett 17:3826-30. 2007....
Oligosaccharides as receptors for JC virusRika Komagome
Laboratory of Molecular and Cellular Pathology, School of Medicine, Hokkaido University, CREST, JST, N15 W7, Kita-ku, Sapporo 060-8638, Japan
J Virol 76:12992-3000. 2002..These results suggest that the oligosaccharides of glycoproteins and glycolipids work as JCV receptors and may be feasible as anti-JCV agents...
An avian influenza H5N1 virus that binds to a human-type receptorPrasert Auewarakul
Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
J Virol 81:9950-5. 2007..Our data confirm the presence of H5N1 virus with the ability to bind to a human-type receptor in this patient and suggest the selection and expansion of the mutant with human-type receptor specificity in the human host environment...
Chemoenzymatic synthesis and application of glycopolymers containing multivalent sialyloligosaccharides with a poly(L-glutamic acid) backbone for inhibition of infection by influenza virusesKazuhide Totani
Department of Applied Biological Chemistry, Shizuoka University, Ohya 836, Shizuoka 422-8529, Japan
Glycobiology 13:315-26. 2003..Inhibition of infection by viruses was remarkably enhanced by increasing the molecular weight and sialic acid content of glycopolymers...
In vitro inhibition of human influenza A virus infection by fruit-juice concentrate of Japanese plum (Prunus mume SIEB. et ZUCC)Sangchai Yingsakmongkon
Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, 1200 Matsumoto, Kasugai, Aichi 487 8501, Japan
Biol Pharm Bull 31:511-5. 2008....
A simple screening assay for receptor switching of avian influenza virusesOrnpreya Suptawiwat
Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
J Clin Virol 42:186-9. 2008..The currently available assays for receptor-binding preference are complex and not widely available...
Identification of glycosphingolipid receptors for pierisin-1, a guanine-specific ADP-ribosylating toxin from the cabbage butterflyYuko Matsushima-Hibiya
Cancer Prevention Division, National Cancer Center Research Institute, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
J Biol Chem 278:9972-8. 2003..Thus, our results suggest that pierisin-1 binds to Gb3 and Gb4 receptors at the C-terminal region, in a manner similar to ricin, and then exhibits cytotoxicity after incorporation into the cell...
Characterization of a human H5N1 influenza A virus isolated in 2003Kyoko Shinya
Department of Virology, Institute of Medical Science, University of Tokyo, Japan
J Virol 79:9926-32. 2005..This case challenges the view that adaptation to land-based poultry is a prerequisite for the replication of aquatic avian influenza A viruses in humans...
Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virusDarwyn Kobasa
Department of Pathobiological Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA
Nature 431:703-7. 2004....
Sialyl alpha(2-->3) lactose clusters using carbosilane dendrimer core scaffolds as influenza hemagglutinin blockersHiroyuki Oka
Division of Material Science, Graduate School of Science and Engineering, Saitama University, Sakura, Saitama 338 8570, Japan
Bioorg Med Chem Lett 18:4405-8. 2008....
Design of N-acetyl-6-sulfo-beta-d-glucosaminide-based inhibitors of influenza virus sialidaseKenji Sasaki
Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Chikusa-ku, Nagoya 464-8603, Japan
Bioorg Med Chem 12:1367-75. 2004..The activity was enhanced nearly 100-fold when the pNP group of 1a was converted to p-acetamidophenyl one 5 (IC(50)=30 microM) or replaced with 1-naphthyl 6 (IC(50)=10 microM) or n-propyl one 8 (IC(50)=11 microM)...
Antigenic alteration of influenza B virus associated with loss of a glycosylation site due to host-cell adaptationTakehiko Saito
Department of Virology III, National Institute of Infectious Diseases, Tokyo, Japan
J Med Virol 74:336-43. 2004....
Enhanced expression of an alpha2,6-linked sialic acid on MDCK cells improves isolation of human influenza viruses and evaluation of their sensitivity to a neuraminidase inhibitorShuji Hatakeyama
Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
J Clin Microbiol 43:4139-46. 2005..We conclude that the human ST6Gal I-expressing MDCK cell line is useful not only for evaluating their sensitivity to NA inhibitors, but also for isolation of influenza viruses from clinical samples...
Glycotentacles: synthesis of cyclic glycopeptides, toward a tailored blocker of influenza virus hemagglutininTakashi Ohta
Division of Biological Sciences, Graduate School of Science, Frontier Research Center for Post-Genomic Science and Technology, Hokkaido University, Kita 21 Nishi 11, Sapporo 001-0021, Japan
Angew Chem Int Ed Engl 42:5186-9. 2003
Avian flu: isolation of drug-resistant H5N1 virusQ Mai Le
National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
Nature 437:1108. 2005..Further investigation is necessary to determine the prevalence of oseltamivir-resistant H5N1 viruses among patients treated with this drug...
Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organsKatsuyuki Fukuda
Department of Molecular Embryology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
Dev Biol 255:278-89. 2003..Together, the data suggest that Foxl1 might be involved in cellular responses of gut-associated lymphoid tissues dependent upon the Lymphotoxins/Lymphotoxin beta-receptor axis...
The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1Atsushi Jinno-Oue
Department of Virology and Preventive Medicine, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma 371 8511, Japan
J Biol Chem 280:30924-34. 2005....
Functional analysis of mouse 3-phosphoglycerate dehydrogenase (Phgdh) gene promoter in developing brainMotohiro Shimizu
Neuronal Circuit Mechanism Research Group, RIKEN Brain Science Institute, Wako, Saitama, Japan
J Neurosci Res 76:623-32. 2004..These observations suggest the presence of cis-acting elements that confer the cell type specificity of Phgdh transcription in the distal promoter region...
Therapeutic effect of sulphated hyaluronic acid, a potential selectin-blocking agent, on experimental progressive mesangial proliferative glomerulonephritisMitsuhiro Matsuda
Department of Medicine III, Okayama University Medical School, Japan
J Pathol 198:407-14. 2002..Sulphated oligosaccharides may be beneficial for the therapy of mesangial proliferative glomerulonephritis...
Asialo-GM1 and asialo-GM2 are putative adhesion molecules for Moraxella catarrhalisKamruddin Ahmed
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Med Microbiol Immunol 191:5-10. 2002..Our results indicate that Gg4Cer on human pharyngeal epithelial cells, and Gg3Cer,possibly on other cells, could serve as molecules for attachment of M. catarrhalis...
Butyrate reduces colonic paracellular permeability by enhancing PPARgamma activationMako Kinoshita
The Second Department of Internal Medicine, School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 0856, Japan
Biochem Biophys Res Commun 293:827-31. 2002..01). These findings suggest that the effect of butyrate on paracellular permeability has apparently taken place through PPARgamma activation and this effect attributes to preventing inflammation of the colon...
Comprehensive analysis of monoclonal antibodies against detergent-insoluble membrane/lipid rafts of HL60 cellsYasuhiro Yamazaki
Laboratory for Neural Architecture, Advanced Technology Development Group, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan
J Immunol Methods 311:106-16. 2006..Interestingly, MAbs belonging to the former group had the potential to induce cell proliferation/differentiation in vitro. Our MAbs against the DIM fraction of HL60 cells can be valuable tools for the study of membrane microdomains...
Influence of glycosylation on the efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239 in a macaque AIDS modelKazuyasu Mori
AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan
J Virol 79:10386-96. 2005..This study demonstrated that the prime-boost Env vaccine was effective against homologous SIVmac239 challenge. Changes in glycosylation affected both cell-mediated and humoral immune responses and vaccine efficacy...
Regulation of self-incompatibility by acetylcholine and cAMP in Lilium longiflorumTakafumi Tezuka
Division of Life Sciences, Graduate School of Science, Nagoya University, Chikusa ku, Nagoya, 464 8601, Japan
J Plant Physiol 164:878-85. 2007....
Cerebroside sulfotransferase deficiency ameliorates L-selectin-dependent monocyte infiltration in the kidney after ureteral obstructionDaisuke Ogawa
Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8558, Japan
J Biol Chem 279:2085-90. 2004..Our results suggest that sulfatide is a major L-selectin-binding molecule in the kidney and that the interaction between L-selectin and sulfatide plays a critical role in monocyte infiltration into the kidney interstitium...
Chemoenzymatic synthesis of artificial glycopolypeptides containing multivalent sialyloligosaccharides with a gamma-polyglutamic acid backbone and their effect on inhibition of infection by influenza virusesMakoto Ogata
Science of Biological Resource, The United Graduate School of Agricultural Science, Gifu University, Yanagido 1 1, Gifu 501 1193, Japan
Bioorg Med Chem 15:1383-93. 2007..Taken together, these results indicate that the binding of viruses to terminal sialic acids is markedly affected by the structure of the asialo portion, in this case either LacNAc or lactose, in the sugar chain of glycopolypeptides...
Sulfatide and its synthetic analogues recognition by Moraxella catarrhalisPinar Ozcelik
Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
Microbiol Immunol 50:967-70. 2006..catarrhalis significantly at an optimum concentration of 10 microg/ml. Synthetic sulfatides may have the potential to be used as a therapy to prevent M. catarrhalis infections...
Reduction of Smad3 accelerates re-epithelialization in a murine model of colitisAtsuko Tokumasa
Clinical Cell Biology F5, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ward, Chiba City 260 8670, Japan
Biochem Biophys Res Commun 317:377-83. 2004..Suppression of TGF-beta1 induction in the colonic mucosa of the heterozygotes may lead to a higher level of proliferation of intestinal epithelial cells...
Glycobiological study of adult Opisthorchis viverrini: characterization of N-linked oligosaccharidesKrajang Talabnin
Graduate School, Khon Kaen University, 40002 Khon Kaen, Thailand
Mol Biochem Parasitol 147:230-3. 2006
Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayersHidekazu Morita
Clinical Cell Biology F5, Graduate School of Medicine, Chiba University, 260 8670, Chuo Ward, Japan
Exp Cell Res 298:1-8. 2004..These results suggest that Cx26-mediated GJIC may play a crucial role in enhancing the barrier function of Caco-2 cell monolayers...
[Hypolipidemia in malabsorption syndrome]Atsuhito Saiki
Center of Diabetes, Endocrine and Metabolism, Toho University Sakura Medical Center
Nippon Rinsho 65:621-6. 2007
Mouse 3-phosphoglycerate dehydrogenase gene: genomic organization, chromosomal localization, and promoter analysisJunya Mitoma
Glycobiology Program, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA
Gene 334:15-22. 2004....
